{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:03:32Z","timestamp":1784765012507,"version":"3.55.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Liver Disease"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.cld.2026.04.009","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T20:50:25Z","timestamp":1780519825000},"page":"677-699","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intrahepatic Cholestasis of Pregnancy"],"prefix":"10.1016","volume":"30","author":[{"given":"Shital","family":"Gandhi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brianna","family":"Barsanti-Innes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Jolicoeur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ifeyinwa Nwamaka","family":"Nwokoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.cld.2026.04.009_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jogc.2024.102618","article-title":"Guideline No. 452: diagnosis and management of intrahepatic cholestasis of pregnancy","volume":"46","author":"Hobson","year":"2024","journal-title":"J Obstet Gynaecol Can"},{"issue":"5","key":"10.1016\/j.cld.2026.04.009_bib2","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/ajo.13719","article-title":"Intrahepatic cholestasis of pregnancy \u2013 diagnosis and management: a consensus statement of the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ): executive summary","volume":"63","author":"Hague","year":"2023","journal-title":"Aust New Zeal J Obstet Gynaecol"},{"issue":"13","key":"10.1016\/j.cld.2026.04.009_bib3","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.1111\/1471-0528.17206","article-title":"Intrahepatic cholestasis of pregnancy: Green-top Guideline No. 43 June 2022","volume":"129","author":"Girling","year":"2022","journal-title":"BJOG Int J Obstet Gynaecol"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib4","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/AOG.0000000000000346","article-title":"Intrahepatic cholestasis of pregnancy","volume":"124","author":"Williamson","year":"2014","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib5","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/hep.510260216","article-title":"Intrahepatic cholestasis of pregnancy: a French prospective study","volume":"26","author":"Bacq","year":"1997","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.cld.2026.04.009_bib6","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1080\/01443615.2017.1286302","article-title":"Two cases of first onset intrahepatic cholestasis of pregnancy associated with moderate ovarian hyperstimulation syndrome after IVF treatment and review of the literature","volume":"37","author":"Mutlu","year":"2017","journal-title":"J Obstet Gynaecol (Lahore)"},{"issue":"6","key":"10.1016\/j.cld.2026.04.009_bib7","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1002\/hep.27171","article-title":"Transcriptional dynamics of bile salt export pump during pregnancy: mechanisms and implications in intrahepatic cholestasis of pregnancy","volume":"60","author":"Song","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.cld.2026.04.009_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.761255","article-title":"The pathological mechanisms of estrogen-induced cholestasis: current perspectives","volume":"12","author":"Zu","year":"2021","journal-title":"Front Pharmacol"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib9","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/hep.26055","article-title":"Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype","volume":"57","author":"Abu-Hayyeh","year":"2013","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib10","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1034\/j.1399-0004.2001.600106.x","article-title":"Risk of obstetric cholestasis in sisters of index patients","volume":"60","author":"Eloranta","year":"2001","journal-title":"Clin Genet"},{"issue":"47","key":"10.1016\/j.cld.2026.04.009_bib11","doi-asserted-by":"crossref","first-page":"7470","DOI":"10.3748\/wjg.v26.i47.7470","article-title":"Molecular overview of progressive familial intrahepatic cholestasis","volume":"26","author":"Amirneni","year":"2020","journal-title":"World J Gastroenterol"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-11626-x","article-title":"An expanded role for heterozygous mutations of ABCB4, ABCB11, ATP8B1, ABCC2 and TJP2 in intrahepatic cholestasis of pregnancy","volume":"7","author":"Dixon","year":"2017","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib13","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.clinre.2015.12.008","article-title":"The pathophysiology of intrahepatic cholestasis of pregnancy","volume":"40","author":"Dixon","year":"2016","journal-title":"Clin Res Hepatol Gastroenterol"},{"issue":"3","key":"10.1016\/j.cld.2026.04.009_bib14","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.jhep.2023.03.006","article-title":"EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy","volume":"79","author":"Williamson","year":"2023","journal-title":"J Hepatol"},{"issue":"6","key":"10.1016\/j.cld.2026.04.009_bib15","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1007\/s00404-011-2183-4","article-title":"Alteration in placental expression of bile acids transporters OATP1A2, OATP1B1, OATP1B3 in intrahepatic cholestasis of pregnancy","volume":"285","author":"Wang","year":"2012","journal-title":"Arch Gynecol Obstet"},{"issue":"12","key":"10.1016\/j.cld.2026.04.009_bib16","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.placenta.2011.09.006","article-title":"A placental phenotype for intrahepatic cholestasis of pregnancy","volume":"32","author":"Geenes","year":"2011","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib17","doi-asserted-by":"crossref","DOI":"10.1038\/s41572-025-00633-2","article-title":"Intrahepatic cholestasis of pregnancy","volume":"11","author":"Dajti","year":"2025","journal-title":"Nat Rev Dis Primers"},{"issue":"3","key":"10.1016\/j.cld.2026.04.009_bib18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0028-2243(91)90222-7","article-title":"Vasoconstrictive effect of bile acids on isolated human placental chorionic veins","volume":"42","author":"Sep\u00falveda","year":"1991","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"8","key":"10.1016\/j.cld.2026.04.009_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2023.100952","article-title":"Intrahepatic cholestasis of pregnancy and fetal cardiac dysfunction: a systematic review and meta-analysis","volume":"5","author":"Zhan","year":"2023","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"8","key":"10.1016\/j.cld.2026.04.009_bib20","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1111\/j.1471-0528.2004.00166.x","article-title":"Comparison of the arrhythmogenic effects of tauro- and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes","volume":"111","author":"Gorelik","year":"2004","journal-title":"BJOG"},{"issue":"3","key":"10.1016\/j.cld.2026.04.009_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0009689","article-title":"Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes","volume":"5","author":"Sheikh Abdul Kadir","year":"2010","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.cld.2026.04.009_bib22","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.jhep.2020.11.038","article-title":"Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations","volume":"74","author":"Vasavan","year":"2021","journal-title":"J Hepatol"},{"issue":"8","key":"10.1016\/j.cld.2026.04.009_bib23","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1055\/a-1386-3912","article-title":"Management of intrahepatic cholestasis of pregnancy: recommendations of the Working Group on obstetrics and prenatal medicine - section on maternal disorders","volume":"81","author":"Hagenbeck","year":"2021","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib24","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/00016348609158224","article-title":"Effects of cholic acid infusion in fetal lambs","volume":"65","author":"Campos","year":"1986","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"6","key":"10.1016\/j.cld.2026.04.009_bib25","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3109\/00016348609158391","article-title":"Maximal response to oxytocin of the isolated myometrium from pregnant patients with intrahepatic cholestasis","volume":"65","author":"Israel","year":"1986","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1067\/S0002-9378(03)00545-3","article-title":"Bile acids increase response and expression of human myometrial oxytocin receptor","volume":"189","author":"Germain","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.cld.2026.04.009_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms9186","article-title":"Maternal bile acid transporter deficiency promotes neonatal demise","volume":"6","author":"Zhang","year":"2015","journal-title":"Nat Commun"},{"issue":"4","key":"10.1016\/j.cld.2026.04.009_bib28","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1172\/JCI64551","article-title":"The TGR5 receptor mediates bile acid\u2013induced itch and analgesia","volume":"123","author":"Alemi","year":"2013","journal-title":"J Clin Investig"},{"issue":"10174","key":"10.1016\/j.cld.2026.04.009_bib29","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0140-6736(18)31877-4","article-title":"Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses","volume":"393","author":"Ovadia","year":"2019","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib30","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/hep.20336","article-title":"Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates","volume":"40","author":"Glantz","year":"2004","journal-title":"Hepatology"},{"issue":"10","key":"10.1016\/j.cld.2026.04.009_bib31","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1111\/1471-0528.16669","article-title":"Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case\u2013control and cohort study","volume":"128","author":"Mitchell","year":"2021","journal-title":"BJOG Int J Obstet Gynaecol"},{"issue":"5","key":"10.1016\/j.cld.2026.04.009_bib32","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1053\/j.gastro.2024.06.014","article-title":"AGA clinical practice update on pregnancy-related gastrointestinal and liver disease: expert review","volume":"167","author":"Kothari","year":"2024","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib33","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/ajg.2015.430","article-title":"ACG clinical guideline: liver disease and pregnancy","volume":"111","author":"Tran","year":"2016","journal-title":"Am J Gastroenterol"},{"issue":"11\u201312","key":"10.1016\/j.cld.2026.04.009_bib34","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.gofs.2023.09.004","article-title":"La cholestase gravidique : recommandations pour la pratique clinique du Coll\u00e8ge national des gyn\u00e9cologues obst\u00e9triciens fran\u00e7ais","volume":"51","author":"Sentilhes","year":"2023","journal-title":"Gyn\u00e9cologie Obs Fertil S\u00e9nologie"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-023-06209-w","article-title":"Ultrasonographic evaluation of the gallbladder motor function in the diagnosis and prognosis of intrahepatic cholestasis of pregnancy","volume":"24","author":"Tai","year":"2024","journal-title":"BMC Pregnancy Childbirth"},{"issue":"5","key":"10.1016\/j.cld.2026.04.009_bib36","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1515\/jpme.1991.19.5.351","article-title":"Doppler umbilical artery velocimetry in pregnancies complicated by intrahepatic cholestasis","volume":"19","author":"Zimmermann","year":"1991","journal-title":"J Perinat Med"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib37","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3109\/00365521.2015.1064990","article-title":"Pregnancy course in patients with intrahepatic cholestasis of pregnancy treated with very low doses of ursodeoxycholic acid","volume":"51","author":"Grymowicz","year":"2016","journal-title":"Scand J Gastroenterol"},{"issue":"4","key":"10.1016\/j.cld.2026.04.009_bib38","doi-asserted-by":"crossref","first-page":"570.e1","DOI":"10.1016\/j.ajog.2015.06.021","article-title":"Predictors of adverse neonatal outcomes in intrahepatic cholestasis of pregnancy","volume":"213","author":"Kawakita","year":"2015","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib39","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2020.11.002","article-title":"Society for Maternal-Fetal Medicine Consult Series #53: intrahepatic cholestasis of pregnancy: replaces Consult #13, April 2011","volume":"224","author":"Lee","year":"2021","journal-title":"Am J Obstet Gynecol"},{"issue":"13","key":"10.1016\/j.cld.2026.04.009_bib40","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1111\/1471-0528.15926","article-title":"Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study","volume":"126","author":"Manna","year":"2019","journal-title":"BJOG"},{"issue":"S1","key":"10.1016\/j.cld.2026.04.009_bib41","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/j.jhep.2015.02.023","article-title":"New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond","volume":"62","author":"Beuers","year":"2015","journal-title":"J Hepatol"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib42","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/hep.29804","article-title":"Bile acids stimulate cholangiocyte fluid secretion by activation of transmembrane member 16A Cl\u2212 channels","volume":"68","author":"Li","year":"2018","journal-title":"Hepatology"},{"issue":"10201","key":"10.1016\/j.cld.2026.04.009_bib43","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0140-6736(19)31270-X","article-title":"Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial","volume":"394","author":"Chappell","year":"2019","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.cld.2026.04.009_bib44","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S2468-1253(21)00074-1","article-title":"Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis","volume":"6","author":"Ovadia","year":"2021","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.cld.2026.04.009_bib45","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejogrb.2015.03.020","article-title":"Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy","volume":"189","author":"Geenes","year":"2015","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.cld.2026.04.009_bib46","first-page":"14","article-title":"Plasmapheresis in management of severe cholestasis of pregnancy","volume":"2","author":"Polewiczowska","year":"2016","journal-title":"J Case Reports Images Obstet Gynecol"},{"key":"10.1016\/j.cld.2026.04.009_bib47","series-title":"Fetal medicine foundation abstracts","article-title":"Novel use of an ileal bile acid transport inhibitor for severe cholestasis in pregnancy","author":"Martin","year":"2025"},{"key":"10.1016\/j.cld.2026.04.009_bib48","author":"Wium"},{"issue":"S1","key":"10.1016\/j.cld.2026.04.009_bib49","first-page":"S1","article-title":"Efficacy, safety and tolerability of volixibat in patients with intrahepatic cholestasis of pregnancy: a case series of 4 patients. The liver meeting: boston, Massachusetts Nov 10-14, 2023","volume":"78","author":"Ovadia","year":"2023","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib50","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1186\/s12884-025-08168-w","article-title":"Bezafibrate for severe refractory intrahepatic cholestasis of pregnancy: a case report and literature review","volume":"25","author":"Gandelsman","year":"2025","journal-title":"BMC Pregnancy Childbirth"},{"issue":"2","key":"10.1016\/j.cld.2026.04.009_bib51","doi-asserted-by":"crossref","first-page":"e84","DOI":"10.1016\/j.jhep.2023.04.014","article-title":"Use of fenofibrate for intrahepatic cholestasis of pregnancy","volume":"79","author":"Grady","year":"2023","journal-title":"J Hepatol"},{"issue":"7","key":"10.1016\/j.cld.2026.04.009_bib52","article-title":"Pharmacological interventions for treating intrahepatic cholestasis of pregnancy","volume":"7","author":"Walker","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"10.1016\/j.cld.2026.04.009_bib53","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1002\/hep.20952","article-title":"Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid","volume":"42","author":"Glantz","year":"2005","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib54","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0016-5085(93)90035-B","article-title":"Prolonged postpartum course of intrahepatic cholestasis of pregnancy","volume":"105","author":"Olsson","year":"1993","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1016\/j.cld.2026.04.009_bib55","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1111\/aogs.13695","article-title":"Intrahepatic cholestasis of pregnancy and comorbidity: a 44-year follow-up study","volume":"98","author":"H\u00e4m\u00e4l\u00e4inen","year":"2019","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"7","key":"10.1016\/j.cld.2026.04.009_bib56","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1136\/gut.52.7.1025","article-title":"Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy","volume":"52","author":"Savander","year":"2003","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.cld.2026.04.009_bib57","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/S0168-8278(00)80139-7","article-title":"Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management","volume":"33","author":"Lammert","year":"2000","journal-title":"J Hepatol"},{"issue":"7","key":"10.1016\/j.cld.2026.04.009_bib58","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1172\/JCI68927","article-title":"Maternal cholestasis during pregnancy programs metabolic disease in offspring","volume":"123","author":"Papacleovoulou","year":"2013","journal-title":"J Clin Investig"},{"issue":"1","key":"10.1016\/j.cld.2026.04.009_bib59","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1053\/j.gastro.2022.01.060","article-title":"Pregnancy-associated liver diseases","volume":"163","author":"Terrault","year":"2022","journal-title":"Gastroenterology"}],"container-title":["Clinics in Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089326126000437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089326126000437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:34:47Z","timestamp":1784763287000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089326126000437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":59,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1089326126000437"],"URL":"https:\/\/doi.org\/10.1016\/j.cld.2026.04.009","relation":{},"ISSN":["1089-3261"],"issn-type":[{"value":"1089-3261","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intrahepatic Cholestasis of Pregnancy","name":"articletitle","label":"Article Title"},{"value":"Clinics in Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cld.2026.04.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}