{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:17:40Z","timestamp":1789615060403,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinical-genitourinary-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Genitourinary Cancer"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.clgc.2018.05.014","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T17:46:58Z","timestamp":1528134418000},"page":"385-391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Comparison Between 64Cu-PSMA-617 PET\/CT and 18F-Choline PET\/CT Imaging in Early Diagnosis of Prostate Cancer Biochemical Recurrence"],"prefix":"10.1016","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9255-4358","authenticated-orcid":false,"given":"Francesco","family":"Cantiello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Crocerossa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio Ivan","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Gangemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Ferro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihai Dorin","family":"Vartolomei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-1229","authenticated-orcid":false,"given":"Giuseppe","family":"Lucarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Mirabelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Scafuro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Ucciero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottavio","family":"De Cobelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Morgia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocco","family":"Damiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Lucio","family":"Cascini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clgc.2018.05.014_bib1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1001\/jama.294.4.433","article-title":"Risk of prostate cancer\u2013specific mortality following biochemical recurrence after radical prostatectomy","volume":"294","author":"Freedland","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.clgc.2018.05.014_bib2","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1007\/s00259-016-3428-z","article-title":"(11)C-choline PET\/CT for restaging prostate cancer. Results from 4,426 scans in a single-centre patient series","volume":"43","author":"Graziani","year":"2016","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib3","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.eururo.2016.08.002","article-title":"EAU-ESTRO-SIOG guidelines on prostate cancer. Part II: treatment of relapsing, metastatic, and castration-resistant prostate cancer","volume":"71","author":"Cornford","year":"2017","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2018.05.014_bib4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.urology.2015.12.048","volume":"95","author":"Rai","year":"2016","journal-title":"Urology"},{"key":"10.1016\/j.clgc.2018.05.014_bib5","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/s00259-012-2298-2","article-title":"PET imaging with a [68Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions","volume":"40","author":"Afshar-oromieh","year":"2013","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40644-016-0072-6","article-title":"(68)Ga-PSMA ligand PET\/CT in patients with prostate cancer: how we review and report","volume":"16","author":"Rauscher","year":"2016","journal-title":"Cancer Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib7","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.urology.2017.04.019","article-title":"Diagnostic accuracy of (64)copper prostate-specific membrane antigen positron emission tomography\/computed tomography for primary lymph node staging of intermediate- to high-risk prostate cancer: our preliminary experience","volume":"106","author":"Cantiello","year":"2017","journal-title":"Urology"},{"key":"10.1016\/j.clgc.2018.05.014_bib8","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.eururo.2011.10.044","article-title":"Updated nomogram predicting lymph node invasion in patients with prostate cancer undergoing extended pelvic lymph node dissection: the essential importance of percentage of positive cores","volume":"61","author":"Briganti","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2018.05.014_bib9","first-page":"277","article-title":"64Cu-PSMA-617 PET\/CT imaging of prostate adenocarcinoma: first in-human studies","volume":"31","author":"Grubm\u00fcller","year":"2016","journal-title":"Cancer Biother Radiopharm"},{"key":"10.1016\/j.clgc.2018.05.014_bib10","doi-asserted-by":"crossref","first-page":"W361","DOI":"10.2214\/AJR.12.9106","article-title":"Comparative sensitivities of functional MRI sequences in detection of local recurrence of prostate carcinoma after radical prostatectomy or external-beam radiotherapy","volume":"200","author":"Roy","year":"2013","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.clgc.2018.05.014_bib11","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00259-010-1604-0","article-title":"Is there a role for 11C-choline PET\/CT in the early detection of metastatic disease in surgically treated prostate cancer patients with a mild PSA increase\u00a0< 1.5 ng\/mL?","volume":"38","author":"Castellucci","year":"2011","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib12","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.eururo.2013.04.019","article-title":"The role of 11C-choline and 18F-fluorocholine positron emission tomography (PET) and PET\/CT in prostate cancer: a systematic review and meta-analysis","volume":"64","author":"Umbehr","year":"2013","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2018.05.014_bib13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.urolonc.2013.03.006","article-title":"Utility of [11C]choline PET\/CT in guiding lesion-targeted salvage therapies in patients with prostate cancer recurrence localized to a single lymph node at imaging: results from a pathologically validated series","volume":"32","author":"Passoni","year":"2014","journal-title":"Urol Oncol"},{"key":"10.1016\/j.clgc.2018.05.014_bib14","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.radonc.2011.05.005","article-title":"Influence of (11)C-choline PET\/CT on the treatment planning for salvage radiation therapy in patients with biochemical recurrence of prostate cancer","volume":"99","author":"Souvatzoglou","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clgc.2018.05.014_bib15","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.eururo.2012.09.039","article-title":"Utility of choline positron emission tomography\/computed tomography for lymph node involvement identification in intermediate- to highrisk prostate cancer: a systematic literature review and metaanalysis","volume":"63","author":"Evangelista","year":"2013","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2018.05.014_bib16","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1515\/cclm-2013-0675","article-title":"Relationship between prostate-specific antigen kinetics and detection rate of radiolabelled choline PET\/CT in restaging prostate cancer patients: a meta-analysis","volume":"52","author":"Treglia","year":"2014","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.clgc.2018.05.014_bib17","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.eururo.2018.01.006","article-title":"Efficacy, predictive factors, and prediction nomograms for Ga-labeled prostate-specific membrane antigen\u2013ligand positron\u2013emission tomography\/computed tomography in early biochemical recurrent prostate cancer after radical prostatectomy","volume":"73","author":"Rauscher","year":"2018","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2018.05.014_bib18","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/j.eururo.2016.06.021","article-title":"Sensitivity, specificity, and predictors of positive (68)Ga-prostate-specific membrane antigen positron emission tomography in advanced prostate cancer: a systematic review and meta-analysis","volume":"70","author":"Perera","year":"2016","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2018.05.014_bib19","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1007\/s00259-017-3670-z","article-title":"(68)Ga-PSMA PET\/CT: joint EANM and SNMMI procedure guideline for prostate cancer imaging: version 1.0","volume":"44","author":"Fendler","year":"2017","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib20","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.7150\/thno.13348","article-title":"PSMA ligands for radionuclide imaging and therapy of prostate cancer: clinical status","volume":"5","author":"L\u00fctje","year":"2015","journal-title":"Theranostics"},{"key":"10.1016\/j.clgc.2018.05.014_bib21","doi-asserted-by":"crossref","first-page":"668","DOI":"10.2967\/jnumed.115.154153","article-title":"Evaluation of hybrid 68Ga-PSMA ligand PET\/CT in 248 patients with biochemical recurrence after radical prostatectomy","volume":"56","author":"Eiber","year":"2015","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.clgc.2018.05.014_bib22","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s00259-014-2949-6","article-title":"The diagnostic value of PET\/CT imaging with the (68)Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer","volume":"42","author":"Afshar-Oromieh","year":"2015","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib23","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1148\/rg.2016150059","article-title":"Molecular imaging of prostate cancer","volume":"36","author":"Wibmer","year":"2016","journal-title":"Radiographics"},{"key":"10.1016\/j.clgc.2018.05.014_bib24","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1007\/s00259-015-3078-6","article-title":"(68)Ga-PSMA PET\/CT for restaging recurrent prostate cancer: which factors are associated with PET\/CT detection rate?","volume":"42","author":"Ceci","year":"2015","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clgc.2018.05.014_bib25","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00259-015-3240-1","article-title":"Extent of disease in recurrent prostate cancer determined by [(68)Ga]PSMA-HBED-CC PET\/CT in relation to PSA levels, PSA doubling time and Gleason score","volume":"43","author":"Verburg","year":"2016","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["Clinical Genitourinary Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1558767318301812?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1558767318301812?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T11:30:38Z","timestamp":1761564638000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1558767318301812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S1558767318301812"],"URL":"https:\/\/doi.org\/10.1016\/j.clgc.2018.05.014","relation":{},"ISSN":["1558-7673"],"issn-type":[{"value":"1558-7673","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison Between 64Cu-PSMA-617 PET\/CT and 18F-Choline PET\/CT Imaging in Early Diagnosis of Prostate Cancer Biochemical Recurrence","name":"articletitle","label":"Article Title"},{"value":"Clinical Genitourinary Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clgc.2018.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}