{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:46:16Z","timestamp":1793094376694,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinical-genitourinary-cancer.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Genitourinary Cancer"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.clgc.2021.11.016","type":"journal-article","created":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T03:31:20Z","timestamp":1640316680000},"page":"198.e1-198.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Contemporary Trends of Systemic Neoadjuvant and Adjuvant Intravesical Chemotherapy in Patients With Upper Tract Urothelial Carcinomas Undergoing Minimally Invasive or Open Radical Nephroureterectomy: Analysis of US Claims on Perioperative Outcomes and Health Care Costs"],"prefix":"10.1016","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3865-5988","authenticated-orcid":false,"given":"Francesco","family":"Del Giudice","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4484-5489","authenticated-orcid":false,"given":"Stefanie","family":"van Uem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernandino L.","family":"Vilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Sciarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Salciccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7291-0316","authenticated-orcid":false,"given":"Gian Maria","family":"Busetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Maggi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Tiberia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Viscuso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Canale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8466-918X","authenticated-orcid":false,"given":"Valeria","family":"Panebianco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5180-7865","authenticated-orcid":false,"given":"Martina","family":"Pecoraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Ferro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Moschini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Krajewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1625-1077","authenticated-orcid":false,"given":"David","family":"D'Andrea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni E.","family":"Cacciamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9070-5706","authenticated-orcid":false,"given":"Andrea","family":"Mari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Soria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Porpiglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Fiori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5425-5453","authenticated-orcid":false,"given":"Daniele","family":"Amparore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7901-5608","authenticated-orcid":false,"given":"Enrico","family":"Checcucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Autorino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ettore","family":"De Berardinis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9660-2732","authenticated-orcid":false,"given":"Benjamin I.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clgc.2021.11.016_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.urolonc.2018.12.002","article-title":"Preoperative multiplex nomogram for prediction of high-risk nonorgan-confined upper-tract urothelial carcinoma","volume":"37","author":"Petros","year":"2019","journal-title":"Urol Oncol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2147\/OTT.S225301","article-title":"Optimal management of upper tract urothelial carcinoma: current perspectives","volume":"13","author":"Leow","year":"2020","journal-title":"Onco Targets Ther"},{"key":"10.1016\/j.clgc.2021.11.016_bib0003","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.eururo.2020.05.042","article-title":"European Association of Urology Guidelines on upper urinary tract urothelial carcinoma: 2020 update","volume":"79","author":"Roupr\u00eat","year":"2021","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0004","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00345-017-2040-6","article-title":"Minimally invasive vs open nephrectomy in the modern era: does approach matter?","volume":"35","author":"Golombos","year":"2017","journal-title":"World J Urol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0005","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.eururo.2011.12.026","article-title":"Propensity-score-matched comparison of perioperative outcomes between open and laparoscopic nephroureterectomy: a national series","volume":"61","author":"Hanna","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0006","doi-asserted-by":"crossref","first-page":"114","DOI":"10.23736\/S2724-6051.20.03689-9","article-title":"Thulium-laser retrograde intra renal ablation of upper urinary tract transitional cell carcinoma: an ESUT Study","volume":"73","author":"Bozzini","year":"2021","journal-title":"Minerva Urol Nephrol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0007","doi-asserted-by":"crossref","first-page":"245","DOI":"10.23736\/S2724-6051.20.03710-8","article-title":"Conservative treatment of upper urinary tract carcinoma in patients with imperative indications","volume":"73","author":"Proietti","year":"2021","journal-title":"Minerva Urol Nephrol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0008","article-title":"Single-dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma","volume":"5","author":"Hwang","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.clgc.2021.11.016_bib0009","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1159\/000350508","article-title":"Prophylactic intravesical chemotherapy to prevent bladder tumors after nephroureterectomy for primary upper urinary tract urothelial carcinomas: a systematic review and meta-analysis","volume":"91","author":"Fang","year":"2013","journal-title":"Urol Int"},{"key":"10.1016\/j.clgc.2021.11.016_bib0010","doi-asserted-by":"crossref","first-page":"e20184","DOI":"10.1097\/MD.0000000000020184","article-title":"Impact of neoadjuvant chemotherapy on survival prognosis and pathological downstaging in patients presenting with high-risk upper tract urothelial carcinoma: a protocol for systematic review and meta-analysis","volume":"99","author":"Li","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.clgc.2021.11.016_bib0011","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.eururo.2016.01.044","article-title":"Robot-assisted versus open radical prostatectomy: a contemporary analysis of an all-payer discharge database","volume":"70","author":"Leow","year":"2016","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0012","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1056\/NEJMoa041895","article-title":"Perioperative beta-blocker therapy and mortality after major noncardiac surgery","volume":"353","author":"Lindenauer","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clgc.2021.11.016_bib0013","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1001\/jama.2013.186","article-title":"Robotically assisted vs laparoscopic hysterectomy among women with benign gynecologic disease","volume":"309","author":"Wright","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.clgc.2021.11.016_bib0014","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"10.1016\/j.clgc.2021.11.016_bib0015","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","article-title":"Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases","volume":"45","author":"Deyo","year":"1992","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0016","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s12957-021-02236-z","article-title":"Oncological outcomes of laparoscopic versus open nephroureterectomy for the treatment of upper tract urothelial carcinoma: an updated meta-analysis","volume":"19","author":"Piszczek","year":"2021","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0017","article-title":"Comparison of oncological and perioperative outcomes of open, laparoscopic, and robotic nephroureterectomy approaches in patients with non-metastatic upper-tract urothelial carcinoma","volume":"14","author":"Lee","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.clgc.2021.11.016_bib0018","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.eururo.2009.06.013","article-title":"Laparoscopic versus open nephroureterectomy: perioperative and oncologic outcomes from a randomised prospective study","volume":"56","author":"Simone","year":"2009","journal-title":"Eur Urol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0019","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/S0140-6736(20)30415-3","article-title":"Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial","volume":"395","author":"Birtle","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.clgc.2021.11.016_bib0020","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.critrevonc.2019.01.019","article-title":"Effect of neoadjuvant chemotherapy on locally advanced upper tract urothelial carcinoma: a systematic review and meta-analysis","volume":"135","author":"Kim","year":"2019","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0021","doi-asserted-by":"crossref","DOI":"10.1111\/bju.15346","article-title":"Trends in the use of neoadjuvant chemotherapy and oncological outcomes for high-risk upper tract urothelial carcinoma: a multicentre retrospective study","author":"Hamaya","year":"2021","journal-title":"BJU Int"},{"key":"10.1016\/j.clgc.2021.11.016_bib0022","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/j.urolonc.2014.05.001","article-title":"Cost-effectiveness of neoadjuvant chemotherapy before radical cystectomy for muscle-invasive bladder cancer","volume":"32","author":"Stevenson","year":"2014","journal-title":"Urol Oncol"},{"key":"10.1016\/j.clgc.2021.11.016_bib0023","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/bju.15230","article-title":"Two cycles of neoadjuvant chemotherapy improves survival in patients with high-risk upper tract urothelial carcinoma","volume":"127","author":"Zennami","year":"2021","journal-title":"BJU Int"}],"container-title":["Clinical Genitourinary Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1558767321002433?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1558767321002433?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T11:34:18Z","timestamp":1761564858000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1558767321002433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S1558767321002433"],"URL":"https:\/\/doi.org\/10.1016\/j.clgc.2021.11.016","relation":{},"ISSN":["1558-7673"],"issn-type":[{"value":"1558-7673","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contemporary Trends of Systemic Neoadjuvant and Adjuvant Intravesical Chemotherapy in Patients With Upper Tract Urothelial Carcinomas Undergoing Minimally Invasive or Open Radical Nephroureterectomy: Analysis of US Claims on Perioperative Outcomes and Health Care Costs","name":"articletitle","label":"Article Title"},{"value":"Clinical Genitourinary Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clgc.2021.11.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}