{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T11:30:58Z","timestamp":1780918258774,"version":"3.54.1"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.clim.2017.05.010","type":"journal-article","created":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T10:55:06Z","timestamp":1494500106000},"page":"73-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["The association between semaphorin 3A levels and gluten-free diet in patients with celiac disease"],"prefix":"10.1016","volume":"184","author":[{"given":"Aharon","family":"Kessel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahava","family":"Vadasz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina","family":"Peri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasren","family":"Eiza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drora","family":"Berkowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.clim.2017.05.010_bb0005","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/nri3407","article-title":"Triggers and drivers of autoimmunity: lessons from coeliac disease","volume":"2013","author":"Sollid","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0010","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1146\/annurev-immunol-040210-092915","article-title":"Integration of genetic and immunological insights into a model of celiac disease pathogenesis","volume":"29","author":"Abadie","year":"2011","journal-title":"Ann. Rev. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0015","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1586\/eci.09.30","article-title":"Celiac sprue: a unique autoimmune disorder","volume":"5","author":"Rashtak","year":"2009","journal-title":"Expert. Rev. Clin. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0020","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/0092-8674(93)90625-Z","article-title":"The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules","volume":"75","author":"Kolodkin","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.clim.2017.05.010_bb0025","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/ni1553","article-title":"Semaphorins and their receptors in immune cell interactions","volume":"9","author":"Suzuki","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0030","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/nri1003","article-title":"Semaphorins in interactions between T cells and antigen presenting cells","volume":"3","author":"Kikutani","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0035","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/cmi.2009.111","article-title":"Regulation of immune cell responses by semaphorins and their receptors","volume":"7","author":"Takamatsu","year":"2010","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0040","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/eji.200324799","article-title":"Neuropilin-1: a surface marker of regulatory T cells","volume":"34","author":"Bruder","year":"2004","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0045","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1002\/eji.200535601","article-title":"Immunosuppressive role of semaphorin 3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization","volume":"36","author":"Lepelleteir","year":"2006","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0050","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.immuni.2008.01.012","article-title":"Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition","volume":"28","author":"Sarris","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.clim.2017.05.010_bb0055","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1073\/pnas.1008721108","article-title":"Neuropilin-1 attenuates autoreactivity in experimental autoimmune encephalomyelitis","volume":"108","author":"Solomon","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.clim.2017.05.010_bb0060","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.immuni.2009.04.010","article-title":"Mechanisms of foxp3+ T regulatory cell-mediated suppression","volume":"30","author":"Shevach","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.clim.2017.05.010_bb0065","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.immuni.2008.02.012","article-title":"Neuropilin-1: the glue between regulatory T cells and dendritic cells?","volume":"28","author":"Mizui","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.clim.2017.05.010_bb0070","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1097\/00042737-199910000-00019","article-title":"The histopathology of coeliac disease: time for a standardized report scheme for pathologists","volume":"11","author":"Oberhuber","year":"1999","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.clim.2017.05.010_bb0075","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1056\/NEJMra071600","article-title":"Celiac disease","volume":"357","author":"Green","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.clim.2017.05.010_bb0080","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1007\/s00431-012-1714-8","article-title":"Clinical practice: coeliac disease","volume":"171","author":"Kneepkens","year":"2012","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.clim.2017.05.010_bb0085","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0140-6736(09)60254-3","article-title":"Coeliac disease","volume":"373","author":"Di Sabatino","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.clim.2017.05.010_bb0090","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.4049\/jimmunol.170.5.2719","article-title":"Celiac disease association with CD8+ T cell responses: identification of a novel gliadin-derived HLA-A2-restricted epitope","volume":"170","author":"Gianfrani","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0095","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.4049\/jimmunol.167.3.1245","article-title":"CD4+CD25high regulatory cells in human peripheral blood","volume":"167","author":"Baecher-Allan","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0100","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1172\/JCI19441","article-title":"Induction of Foxp3 and acqustion of T regulaotry activity by stimulated human CD4+CD25\u2013 T cells","volume":"112","author":"Walke","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.clim.2017.05.010_bb0105","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1172\/JCI36389","article-title":"Evidence that cytokines play a role in rheumatoid arthritis","volume":"118","author":"Brennan","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.clim.2017.05.010_bb0110","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.2353\/ajpath.2009.080987","article-title":"Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications","volume":"174","author":"Andr\u00e9","year":"2009","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.clim.2017.05.010_bb0115","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/ajg.2011.397","article-title":"Impaired control of effector T cells by regulatory T cells: a clue to loss of oral tolerance and autoimmunity in celiac disease?","volume":"107","author":"Hmida","year":"2012","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.clim.2017.05.010_bb0120","doi-asserted-by":"crossref","first-page":"6373","DOI":"10.4049\/jimmunol.0903527","article-title":"The neuroimmune semaphorin-3A reduces inflammation and progression of experimental autoimmune arthritis","volume":"185","author":"Catalano","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0125","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/383525a0","article-title":"Semaphorin III is needed for normal patterning and growth of nerves, bones and heart","volume":"383","author":"Behar","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.clim.2017.05.010_bb0130","doi-asserted-by":"crossref","first-page":"26294","DOI":"10.1074\/jbc.M609711200","article-title":"Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis","volume":"282","author":"Guttmann-Raviv","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.clim.2017.05.010_bb0135","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1182\/blood-2007-06-096529","article-title":"Semaphorin3A signaling controls Fas (CD95)-mediated apoptosis by promoting Fas translocation into lipid rafts","volume":"111","author":"Moretti","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.05.010_bb0140","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1182\/blood-2004-10-4092","article-title":"Negative regulation of platelet function by a secreted cell repulsive protein, semaphorin 3A","volume":"106","author":"Kashiwagi","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.05.010_bb0145","doi-asserted-by":"crossref","first-page":"4348","DOI":"10.4049\/jimmunol.166.7.4348","article-title":"Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration","volume":"166","author":"Delaire","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0150","first-page":"233","article-title":"Neuropilin-1 mediates collapsin-1\/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165","volume":"146","author":"Miao","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.clim.2017.05.010_bb0155","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1002\/eji.200535601","article-title":"Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization","volume":"36","author":"Lepelletier","year":"2006","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.clim.2017.05.010_bb0160","doi-asserted-by":"crossref","first-page":"3002","DOI":"10.1523\/JNEUROSCI.4963-03.2004","article-title":"Netrin-1 and semaphorin 3A promote or inhibit cortical axon branching, respectively, by reorganization of the cytoskeleton","volume":"24","author":"Dent","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.clim.2017.05.010_bb0165","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1182\/blood-2005-06-2445","article-title":"Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function","volume":"107","author":"Catalano","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.05.010_bb0170","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1002\/eji.200535601","article-title":"Hermine, Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization","volume":"36","author":"Lepelletier","year":"2006","journal-title":"Eur. J. Immunol."}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661616305976?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661616305976?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T19:54:23Z","timestamp":1535831663000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521661616305976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":34,"alternative-id":["S1521661616305976"],"URL":"https:\/\/doi.org\/10.1016\/j.clim.2017.05.010","relation":{},"ISSN":["1521-6616"],"issn-type":[{"value":"1521-6616","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The association between semaphorin 3A levels and gluten-free diet in patients with celiac disease","name":"articletitle","label":"Article Title"},{"value":"Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clim.2017.05.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}