{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T16:07:08Z","timestamp":1761494828100,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP26461570"],"award-info":[{"award-number":["JP26461570"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.clim.2017.08.003","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T09:46:37Z","timestamp":1501753597000},"page":"112-120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Maternal T and B cell engraftment in two cases of X-linked severe combined immunodeficiency with IgG1 gammopathy"],"prefix":"10.1016","volume":"183","author":[{"given":"Tsubasa","family":"Okano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5012-0906","authenticated-orcid":false,"given":"Takuro","family":"Nishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eri","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehiro","family":"Takashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu-Wen","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoi","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2561-2535","authenticated-orcid":false,"given":"Mari","family":"Tanaka-Kubota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Mitsuiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifumi","family":"Kawano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2132-8403","authenticated-orcid":false,"given":"Kohsuke","family":"Imai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Kanegane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Morio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clim.2017.08.003_bb0005","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.0105-2896.2004.00203.x","article-title":"Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways","volume":"202","author":"Kovanen","year":"2004","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.clim.2017.08.003_bb0010","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/S0022-3476(97)70199-9","article-title":"Human severe combined immunodeficiency: genetic, phenotypic, and functional diversity in one hundred eight infants","volume":"130","author":"Buckley","year":"1997","journal-title":"J. Pediatr."},{"key":"10.1016\/j.clim.2017.08.003_bb0015","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/S0022-3476(05)80951-5","article-title":"Severe combined immunodeficiency: a retrospective single-center study of clinical presentation and outcome in 117 patients","volume":"123","author":"Stephan","year":"1993","journal-title":"J. Pediatr."},{"key":"10.1016\/j.clim.2017.08.003_bb0020","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1182\/blood.V98.6.1847","article-title":"Transplacentally acquired maternal T lymphocytes in severe combined immunodeficiency: a study of 121 patients","volume":"98","author":"M\u00fcller","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.08.003_bb0025","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/BF00918661","article-title":"Monoclonal gammopathies in children","volume":"9","author":"Gerritsen","year":"1989","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0030","first-page":"53","article-title":"Monoclonal IgA gammopathy due to maternal B cells in an infant with severe combined immunodeficiency (SCID) prior to hematopoietic stem cell transplantation","volume":"28","author":"Kobrynski","year":"2006","journal-title":"J. Pediatr. Hematol. Oncol."},{"key":"10.1016\/j.clim.2017.08.003_bb0035","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.clim.2012.08.011","article-title":"Monoclonal IgG kappa gammopathy previous to hematopoietic stem cell transplantation in an infant with severe combined immunodeficiency","volume":"145","author":"Sim\u00e3o","year":"2012","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0040","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/1824-7288-36-76","article-title":"Genetics of SCID","volume":"36","author":"Cossu","year":"2010","journal-title":"Ital. J. Pediatr."},{"key":"10.1016\/j.clim.2017.08.003_bb0045","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.bbmt.2008.04.001","article-title":"Recipient-derived cells after cord blood transplantation: dynamics elucidated by multicolor FACS, reflecting graft failure and relapse","volume":"14","author":"Watanabe","year":"2008","journal-title":"Biol. Blood Marrow Transpl."},{"key":"10.1016\/j.clim.2017.08.003_bb0050","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/gene.2010.68","article-title":"The human G1m1 allotype associates with CD4+ T-cell responsiveness to a highly conserved IgG1 constant region peptide and confers an asparaginyl endopeptidase cleavage site","volume":"12","author":"Stickler","year":"2011","journal-title":"Genes Immun."},{"key":"10.1016\/j.clim.2017.08.003_bb0055","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/978-1-61779-842-9_34","article-title":"Human Gm, Km, and Am allotypes and their molecular characterization: a remarkable demonstration of polymorphism","volume":"882","author":"Lefranc","year":"2012","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.clim.2017.08.003_bb0060","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/ni974","article-title":"Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination","volume":"4","author":"Imai","year":"2003","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0065","doi-asserted-by":"crossref","first-page":"D1006","DOI":"10.1093\/nar\/gkn838","article-title":"IMGT, the international ImMunoGeneTics information system","volume":"37","author":"Lefranc","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.clim.2017.08.003_bb0070","doi-asserted-by":"crossref","first-page":"W503","DOI":"10.1093\/nar\/gkn316","article-title":"IMGT\/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis","volume":"36","author":"Brochet","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.clim.2017.08.003_bb0075","first-page":"564","article-title":"Two mutational hotspots in the interleukin-2 receptor gamma chain gene causing human X-linked severe combined immunodeficiency","volume":"57","author":"Pepper","year":"1995","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.clim.2017.08.003_bb0080","first-page":"1968","article-title":"Mutation analysis of IL2RG in human X-linked severe combined immunodeficiency","volume":"89","author":"Puck","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.08.003_bb0085","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1002\/1521-4141(200003)30:3<732::AID-IMMU732>3.0.CO;2-L","article-title":"Intrinsic defects of B cell function in X-linked severe combined immunodeficiency","volume":"30","author":"White","year":"2000","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0090","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s001090100271","article-title":"T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation","volume":"79","author":"Hazenberg","year":"2001","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.clim.2017.08.003_bb0095","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/s10875-017-0405-7","article-title":"Multicolor flow cytometry for the diagnosis of primary immunodeficiency diseases","volume":"37","author":"Takashima","year":"2017","journal-title":"J. Clin. Immunol"},{"key":"10.1016\/j.clim.2017.08.003_bb0100","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1182\/blood.V85.8.2105.bloodjournal8582105","article-title":"Engrafted maternal T cells in a severe combined immunodeficiency patient express T-cell receptor variable beta segments characterized by a restricted V-D-J junctional diversity","volume":"85","author":"Sottini","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.08.003_bb0105","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/354389a0","article-title":"Intraclonal generation of antibody mutants in germinal centres","volume":"354","author":"Jacob","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.clim.2017.08.003_bb0110","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jpeds.2009.05.026","article-title":"Identification of severe combined immunodeficiency by T-cell receptor excision circles quantification using neonatal guthrie cards","volume":"155","author":"Morinishi","year":"2009","journal-title":"J. Pediatr."},{"key":"10.1016\/j.clim.2017.08.003_bb0115","doi-asserted-by":"crossref","first-page":"6824","DOI":"10.1182\/blood-2011-06-362533","article-title":"IL-21 is the primary common \u03b3 chain-binding cytokine required for human B-cell differentiation in vivo","volume":"118","author":"Recher","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.clim.2017.08.003_bb0120","doi-asserted-by":"crossref","first-page":"5154","DOI":"10.4049\/jimmunol.172.9.5154","article-title":"IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells","volume":"172","author":"P\u00e8ne","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0125","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.4049\/jimmunol.181.3.1767","article-title":"IL-21-induced isotype switching to IgG and IgA by human na\u00efve B cells is differentially regulated by IL-4","volume":"181","author":"Avery","year":"2008","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.clim.2017.08.003_bb0130","first-page":"65","article-title":"Cytokine-mediated regulation of plasma cell generation: IL-21 takes center stage","volume":"18","author":"Moens","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0135","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1309\/AJCP2JBDEELPA7HT","article-title":"Evaluation of monoclonal and oligoclonal gammopathies in a pediatric population in a major urban center","volume":"141","author":"Karafin","year":"2014","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.clim.2017.08.003_bb0140","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/ACI.0b013e32834c311a","article-title":"Omenn syndrome does not live by V(D)J recombination alone","volume":"11","author":"Marrella","year":"2011","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"issue":"1","key":"10.1016\/j.clim.2017.08.003_bb0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/gad.1161904","article-title":"The generation of antibody diversity through somatic hypermutation and class switch recombination","volume":"18","author":"Li","year":"2004","journal-title":"Genes Dev."},{"key":"10.1016\/j.clim.2017.08.003_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.biochem.76.061705.090740","article-title":"Molecular mechanisms of antibody somatic hypermutation","volume":"76","author":"Di Noia","year":"2007","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.clim.2017.08.003_bb0155","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1146\/annurev.immunol.26.021607.090248","article-title":"Mechanism and regulation of class switch recombination","volume":"26","author":"Stavnezer","year":"2008","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.clim.2017.08.003_bb0160","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1084\/jem.20012065","article-title":"Visualization of the genesis and fate of isotype-switched B cells during a primary immune response","volume":"197","author":"Pape","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.clim.2017.08.003_bb0165","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4103\/0256-4947.62834","article-title":"Delayed presentation of severe combined immunodeficiency due to prolonged maternal T cell engraftment","volume":"30","author":"Al-Muhsen","year":"2010","journal-title":"Ann. Saudi Med."},{"key":"10.1016\/j.clim.2017.08.003_bb0170","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/sj.bmt.1703128","article-title":"Cutaneous manifestations of maternal engraftment in patients with severe combined immunodeficiency: a clinicopathologic study","volume":"28","author":"Denianke","year":"2001","journal-title":"Bone Marrow Transplant."}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152166161730058X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152166161730058X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T15:58:14Z","timestamp":1761494294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152166161730058X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":34,"alternative-id":["S152166161730058X"],"URL":"https:\/\/doi.org\/10.1016\/j.clim.2017.08.003","relation":{},"ISSN":["1521-6616"],"issn-type":[{"type":"print","value":"1521-6616"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal T and B cell engraftment in two cases of X-linked severe combined immunodeficiency with IgG1 gammopathy","name":"articletitle","label":"Article Title"},{"value":"Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clim.2017.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}