{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:22:11Z","timestamp":1792624931638,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31400792"],"award-info":[{"award-number":["31400792"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31400128"],"award-info":[{"award-number":["31400128"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.clim.2018.05.007","type":"journal-article","created":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T20:31:11Z","timestamp":1528835471000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Mechanisms of fibronectin-binding protein A (FnBPA 110\u2013263 ) vaccine efficacy in Staphylococcus aureus sepsis versus skin infection"],"prefix":"10.1016","volume":"194","author":[{"given":"Rui","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Kai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu-Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-Peng","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan-Ming","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian-Fei","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clim.2018.05.007_bb0005","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/S0140-6736(09)61999-1","article-title":"Community-associated meticillin-resistant Staphylococcus aureus","volume":"375","author":"Deleo","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.clim.2018.05.007_bb0010","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0140-6736(10)61371-2","article-title":"Community-associated meticillin-resistant Staphylococcus aureus","volume":"376","author":"Taccetti","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.clim.2018.05.007_bb0015","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S1473-3099(16)30554-0","article-title":"Community-associated meticillin-resistant Staphylococcus aureus pneumonia in China","volume":"17","author":"Zheng","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.clim.2018.05.007_bb0020","first-page":"221","article-title":"Methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococcus faecalis and enterococcus faecium active dimeric isobutyrylphloroglucinol from Ivesia gordonii","volume":"9","author":"Ahmed","year":"2014","journal-title":"Nat. Prod. Commun."},{"key":"10.1016\/j.clim.2018.05.007_bb0025","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1001\/jama.2014.10142","article-title":"Reconsidering isolation precautions for endemic methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus","volume":"312","author":"Morgan","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.clim.2018.05.007_bb0030","doi-asserted-by":"crossref","first-page":"336","DOI":"10.4161\/hv.18946","article-title":"Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17\/IL17 pathway in a murine sepsis model","volume":"8","author":"Joshi","year":"2012","journal-title":"Hum. Vaccines Immunotherapeutics"},{"key":"10.1016\/j.clim.2018.05.007_bb0035","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1128\/IAI.00700-08","article-title":"The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus","volume":"76","author":"Spellberg","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.clim.2018.05.007_bb0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005226","article-title":"Memory Th1 cells are protective in invasive Staphylococcus aureus infection","volume":"11","author":"Brown","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.clim.2018.05.007_bb0045","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1084\/jem.20080218","article-title":"Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3","volume":"205","author":"Ma","year":"2008","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.clim.2018.05.007_bb0050","doi-asserted-by":"crossref","DOI":"10.1038\/nature06764","article-title":"Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome","volume":"452","author":"Milner","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.clim.2018.05.007_bb0055","doi-asserted-by":"crossref","first-page":"E5555","DOI":"10.1073\/pnas.1415610111","article-title":"Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection","volume":"111","author":"Yeaman","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.clim.2018.05.007_bb0060","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1073\/pnas.1424924112","article-title":"Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus","volume":"112","author":"Bagnoli","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.clim.2018.05.007_bb0065","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1007\/s10096-016-2763-0","article-title":"The remarkably multifunctional fibronectin binding proteins of Staphylococcus aureus","volume":"35","author":"Foster","year":"2016","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.clim.2018.05.007_bb0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0095338","article-title":"Identification of the immunodominant regions of Staphylococcus aureus fibronectin-binding protein A","volume":"9","author":"Zuo","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.clim.2018.05.007_bb0075","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1172\/JCI40891","article-title":"IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice","volume":"120","author":"Cho","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.clim.2018.05.007_bb0080","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.immuni.2008.11.009","article-title":"Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses","volume":"30","author":"Ishigame","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.clim.2018.05.007_bb0085","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00430-017-0499-9","article-title":"IL-17A plays an important role in protection induced by vaccination with fibronectin-binding domain of fibronectin-binding protein A against Staphylococcus aureus infection","volume":"206","author":"Narita","year":"2017","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.clim.2018.05.007_bb0090","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1128\/IAI.00447-10","article-title":"Role of interleukin-17A in cell-mediated protection against Staphylococcus aureus infection in mice immunized with the fibrinogen-binding domain of clumping factor a","volume":"78","author":"Narita","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.clim.2018.05.007_bb0095","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1001\/jama.2013.3010","article-title":"Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial","volume":"309","author":"Fowler","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.clim.2018.05.007_bb0100","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1093\/infdis\/jix096","article-title":"Lethal CD4 T cell responses induced by vaccination against Staphylococcus aureus bacteremia","volume":"215","author":"Karauzum","year":"2017","journal-title":"J. Infect. Dis."}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661618301955?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661618301955?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T07:46:27Z","timestamp":1604389587000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521661618301955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":20,"alternative-id":["S1521661618301955"],"URL":"https:\/\/doi.org\/10.1016\/j.clim.2018.05.007","relation":{},"ISSN":["1521-6616"],"issn-type":[{"value":"1521-6616","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanisms of fibronectin-binding protein A (FnBPA110\u2013263) vaccine efficacy in Staphylococcus aureus sepsis versus skin infection","name":"articletitle","label":"Article Title"},{"value":"Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clim.2018.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}