{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T16:14:03Z","timestamp":1761495243627,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004054","name":"King Abdulaziz University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.clim.2022.109014","type":"journal-article","created":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T11:48:14Z","timestamp":1650282494000},"page":"109014","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Spontaneous resolution of severe idiopathic T cell lymphopenia"],"prefix":"10.1016","volume":"238","author":[{"given":"Saddiq B.","family":"Habiballah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Whangbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan D.","family":"Cardona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig D.","family":"Platt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clim.2022.109014_bb0005","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.jaci.2013.09.044","article-title":"Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: the Primary Immune Deficiency Treatment Consortium experience","volume":"133","author":"Shearer","year":"2014","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0010","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1182\/blood-2018-03-840702","article-title":"SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery","volume":"132","author":"Haddad","year":"2018","journal-title":"Blood."},{"key":"10.1016\/j.clim.2022.109014_bb0015","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1056\/NEJMoa1401177","article-title":"Transplantation outcomes for severe combined immunodeficiency, 2000-2009","volume":"371","author":"Pai","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.clim.2022.109014_bb0020","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1001\/jama.2014.9132","article-title":"Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States","volume":"312","author":"Kwan","year":"2014","journal-title":"JAMA - J. Am. Med. Assoc."},{"key":"10.1016\/j.clim.2022.109014_bb0025","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1016\/j.jaip.2021.02.006","article-title":"Ten years of newborn screening for severe combined immunodeficiency (SCID) in Massachusetts","volume":"9","author":"Hale","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.clim.2022.109014_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2017.01448","article-title":"First year of Israeli newborn screening for severe combined immunodeficiency-clinical achievements and insights","volume":"8","author":"Rechavi","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0035","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s10875-020-00956-7","article-title":"Newborn screening for severe combined immunodeficiency: 10-year experience at a single referral center (2009\u20132018)","volume":"41","author":"Thorsen","year":"2021","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0040","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s10875-014-0006-7","article-title":"Newborn screening for SCID in New York state: experience from the first two years","volume":"34","author":"Vogel","year":"2014","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0045","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1542\/peds.2019-2461JJJJ","article-title":"Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California, 2010-2017","volume":"144","author":"Agyemang","year":"2019","journal-title":"Pediatrics."},{"key":"10.1016\/j.clim.2022.109014_bb0050","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.clim.2017.07.002","article-title":"Idiopathic T cell lymphopenia identified in New York State Newborn Screening","volume":"183","author":"Albin-Leeds","year":"2017","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0055","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1182\/blood-2017-05-781849","article-title":"Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study","volume":"130","author":"Heimall","year":"2017","journal-title":"Blood."},{"key":"10.1016\/j.clim.2022.109014_bb0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s10875-019-00737-x","article-title":"Human Inborn Errors of Immunity: 2019 Update on the classification from the International Union of Immunological Societies Expert Committee","volume":"40","author":"Tangye","year":"2020","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0065","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.clim.2010.02.007","article-title":"Thymus transplantation","volume":"135","author":"Markert","year":"2010","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0070","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.jaip.2015.01.026","article-title":"Positive family history, infection, low absolute lymphocyte count (ALC), and absent thymic shadow: diagnostic clues for all molecular forms of severe combined immunodeficiency (SCID)","volume":"3","author":"McWilliams","year":"2015","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.clim.2022.109014_bb0075","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1038\/ni.1662","article-title":"The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency","volume":"9","author":"Shiow","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0080","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/nature02284","article-title":"Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1","volume":"427","author":"Matloubian","year":"2004","journal-title":"Nature."},{"key":"10.1016\/j.clim.2022.109014_bb0085","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jaci.2016.09.057","article-title":"Janus kinase 3 deficiency caused by a homozygous synonymous exonic mutation that creates a dominant splice site","volume":"140","author":"Platt","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.clim.2022.109014_bb0090","first-page":"35","article-title":"Review of fetal and neonatal immune cytopenias","volume":"13","author":"Lewin","year":"2015","journal-title":"Clin. Adv. Hematol. Oncol."}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152166162200095X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152166162200095X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T16:07:32Z","timestamp":1761494852000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152166162200095X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":18,"alternative-id":["S152166162200095X"],"URL":"https:\/\/doi.org\/10.1016\/j.clim.2022.109014","relation":{},"ISSN":["1521-6616"],"issn-type":[{"type":"print","value":"1521-6616"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spontaneous resolution of severe idiopathic T cell lymphopenia","name":"articletitle","label":"Article Title"},{"value":"Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clim.2022.109014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109014"}}