{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T07:21:26Z","timestamp":1775114486941,"version":"3.50.1"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:00:00Z","timestamp":1674518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.clim.2023.109244","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T12:40:03Z","timestamp":1674650403000},"page":"109244","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["In obese hypertensives cholecalciferol inhibits circulating TH17 cells but not macrophage infiltration on adipose tissue"],"prefix":"10.1016","volume":"247","author":[{"given":"Catarina","family":"Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreia","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Coutinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Filipe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e2ncia","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Castelo","family":"Branco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mafalda","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0005","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20171773","article-title":"The immunology of hypertension","volume":"215","author":"Norlander","year":"2018","journal-title":"J. Exp. Med."},{"issue":"12","key":"10.1016\/j.clim.2023.109244_bb0010","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1111\/bph.14436","article-title":"Hypertension: a new treatment for an old disease? Targeting the immune system","volume":"176","author":"Bomfim","year":"2019","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0015","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1152\/physrev.00031.2016","article-title":"Role of the immune system in hypertension","volume":"97","author":"Rodriguez-Iturbe","year":"2017","journal-title":"Physiol. Rev."},{"issue":"7","key":"10.1016\/j.clim.2023.109244_bb0020","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1161\/CIRCRESAHA.121.318052","article-title":"Hypertension","volume":"128","author":"Madhur","year":"2021","journal-title":"Circ. Res."},{"key":"10.1016\/j.clim.2023.109244_bb0025","series-title":"Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction","author":"Madhur","year":"2010"},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0030","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1161\/HYPERTENSIONAHA.116.07237","article-title":"Activation of human T cells in hypertension: studies of humanized mice and hypertensive humans","volume":"68","author":"Itani","year":"2016","journal-title":"Hypertension (Dallas, Tex\u202f: 1979)"},{"issue":"6","key":"10.1016\/j.clim.2023.109244_bb0035","article-title":"Immune regulation of systemic hypertension, pulmonary arterial hypertension, and preeclampsia: shared disease mechanisms and translational opportunities","volume":"313","author":"Jafri","year":"2017","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"issue":"5","key":"10.1016\/j.clim.2023.109244_bb0040","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/joim.12803","article-title":"Inflammation of brown\/beige adipose tissues in obesity and metabolic disease","volume":"284","author":"Villarroya","year":"2018","journal-title":"J. Intern. Med."},{"issue":"August","key":"10.1016\/j.clim.2023.109244_bb0045","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.3389\/fimmu.2018.01961","article-title":"Regulation, communication, and functional roles of adipose tissue-resident CD4+ T cells in the control of metabolic homeostasis","volume":"9","author":"Zhou","year":"2018","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0050","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1189\/jlb.0210072","article-title":"Adipose tissue macrophages: their role in adipose tissue remodeling","volume":"88","author":"Suganami","year":"2010","journal-title":"J. Leukoc. Biol."},{"issue":"9","key":"10.1016\/j.clim.2023.109244_bb0055","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1002\/term.2836","article-title":"CD8+ T cells are involved in early inflammation before macrophages in a rat adipose tissue engineering chamber model","volume":"13","author":"Yuan","year":"2019","journal-title":"J. Tissue Eng. Regen. Med."},{"key":"10.1016\/j.clim.2023.109244_bb0060","series-title":"Inflammatory Mechanisms in Obesity","author":"Gregor","year":"2011"},{"issue":"JULY","key":"10.1016\/j.clim.2023.109244_bb0065","article-title":"Tissue immune cells fuel obesity-associated inflammation in adipose tissue and beyond","volume":"10","author":"Liu","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.clim.2023.109244_bb0070","first-page":"635","article-title":"Inflammation in hypertension","author":"Xiao","year":"2020","journal-title":"NLM (Medline)"},{"key":"10.1016\/j.clim.2023.109244_bb0075","series-title":"Inflammation, Immunity, and Hypertensive End-Organ Damage","first-page":"1022","author":"McMaster","year":"2015"},{"issue":"4","key":"10.1016\/j.clim.2023.109244_bb0080","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1161\/HYPERTENSIONAHA.113.02883","article-title":"Spironolactone decreases DOCA\u2013salt\u2013induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes","volume":"63","author":"Amador","year":"2014","journal-title":"Hypertension."},{"issue":"2","key":"10.1016\/j.clim.2023.109244_bb0085","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.tem.2014.12.001","article-title":"Lymphocyte roles in metabolic dysfunction: of men and mice","volume":"26","author":"Ip","year":"2015","journal-title":"Trends Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0090","doi-asserted-by":"crossref","DOI":"10.1152\/ajprenal.00454.2010","article-title":"Infiltrating T lymphocytes in the kidney increase oxidative stress and participate in the development of hypertension and renal disease","volume":"300","author":"de Miguel","year":"2011","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"6","key":"10.1016\/j.clim.2023.109244_bb0095","article-title":"Role of T-cell activation in salt-sensitive hypertension","volume":"316","author":"Ren","year":"2019","journal-title":"Am. J. Phys. Heart Circ. Phys."},{"key":"10.1016\/j.clim.2023.109244_bb0100","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1152\/ajpheart.01118.2006","article-title":"Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice","volume":"292","author":"Ko","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"7","key":"10.1016\/j.clim.2023.109244_bb0105","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1172\/JCI60113","article-title":"Immune cells control skin lymphatic electrolyte homeostasis and blood pressure","volume":"123","author":"Wiig","year":"2013","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.clim.2023.109244_bb0110","article-title":"White blood cells and blood pressure: a Mendelian randomization study","volume":"1307-17","author":"Siedlinski","year":"2020","journal-title":"Circulation."},{"key":"10.1016\/j.clim.2023.109244_bb0115","series-title":"Animal Models of Hypertension: A Scientific Statement From the American Heart Association","first-page":"e87","author":"Lerman","year":"2019"},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0120","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3945\/an.115.010207","article-title":"Impact of obesity and metabolic syndrome on immunity","volume":"7","author":"Andersen","year":"2016","journal-title":"Adv. Nutr."},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0125","article-title":"Tregs facilitate obesity and insulin resistance via a Blimp-1\/IL-10 axis. JCI","volume":"6","author":"Beppu","year":"2021","journal-title":"Insight."},{"key":"10.1016\/j.clim.2023.109244_bb0130","series-title":"Obesity and Type 2 Diabetes Mellitus Drive Immune Dysfunction, Infection Development, and sepsis Mortality","first-page":"525","author":"Frydrych","year":"2018"},{"issue":"5","key":"10.1016\/j.clim.2023.109244_bb0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0197178","article-title":"Decreased circulating t regulatory lymphocytes in obese patients undergoing bariatric surgery","volume":"13","author":"Agabiti-Rosei","year":"2018","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0140","doi-asserted-by":"crossref","DOI":"10.1186\/s11658-018-0106-0","article-title":"Increased expression and functionality of the gap junction in peripheral blood lymphocytes is associated with hypertension-mediated inflammation in spontaneously hypertensive rats","volume":"23","author":"Ni","year":"2018","journal-title":"Cell. Mol. Biol. Lett."},{"issue":"2","key":"10.1016\/j.clim.2023.109244_bb0145","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2337\/db11-1065","article-title":"Morbidly obese human subjects have increased peripheral blood CD4 + T cells with skewing toward a Treg- and Th2-dominated phenotype","volume":"61","author":"Van Der Weerd","year":"2012","journal-title":"Diabetes."},{"issue":"2","key":"10.1016\/j.clim.2023.109244_bb0150","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.clim.2015.08.002","article-title":"Cholecalciferol supplementation improves suppressive capacity of regulatory T-cells in young patients with new-onset type 1 diabetes mellitus - a randomized clinical trial","volume":"161","author":"Treiber","year":"2015","journal-title":"Clin. Immunol. (Orlando, Fla)"},{"issue":"7","key":"10.1016\/j.clim.2023.109244_bb0155","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1001\/archpediatrics.2012.164","article-title":"Effect of cholecalciferol as adjunctive therapy with insulin on protective immunologic profile and decline of residual \u03b2-cell function in new-onset type 1 diabetes mellitus","volume":"166","author":"Gabbay","year":"2012","journal-title":"Arch. Pediatr. Adolesc. Med."},{"issue":"12","key":"10.1016\/j.clim.2023.109244_bb0160","doi-asserted-by":"crossref","DOI":"10.1007\/s00415-018-9074-6","article-title":"Vitamin D for the treatment of multiple sclerosis: a meta-analysis","volume":"265","author":"McLaughlin","year":"2018","journal-title":"J. Neurol."},{"key":"10.1016\/j.clim.2023.109244_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2017.07.007","article-title":"Modulation of inflammatory and immune responses by vitamin D","volume":"85","author":"Colotta","year":"2017","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.clim.2023.109244_bb0170","first-page":"7","article-title":"Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential","author":"Dankers","year":"2017","journal-title":"Front. Immunol."},{"issue":"24","key":"10.1016\/j.clim.2023.109244_bb0175","article-title":"Vitamin D release across abdominal adipose tissue in lean and obese men: the effect of \u00df-adrenergic stimulation","volume":"7","author":"Pramono","year":"2019","journal-title":"Phys. Rep."},{"key":"10.1016\/j.clim.2023.109244_bb0180","first-page":"57","article-title":"Renoprotective effects of anti-TGF-antibody and antihypertensive therapies in dahl S rats","volume":"303","author":"Murphy","year":"2012","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"issue":"11","key":"10.1016\/j.clim.2023.109244_bb0185","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.3390\/nu10111656","article-title":"Vitamin D: nutrient, hormone, and immunomodulator","volume":"10","author":"Sassi","year":"2018","journal-title":"Nutrients."},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0190","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1159\/000478044","article-title":"Age-dependent changes in regulatory T lymphocyte development and function: a Mini-review","volume":"64","author":"Darrigues","year":"2017","journal-title":"Gerontology."},{"issue":"5\u20136","key":"10.1016\/j.clim.2023.109244_bb0195","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1242\/dmm.001180","article-title":"A comprehensive definition for metabolic syndrome","volume":"2","author":"Huang","year":"2009","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.clim.2023.109244_bb0200","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/730827","article-title":"Visceral adiposity index: An indicator of adipose tissue dysfunction","volume":"2014","author":"Amato","year":"2014","journal-title":"Int. J. Endocrinol."},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0205","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1365-2249.2005.02798.x","article-title":"The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age","volume":"140","author":"Gregg","year":"2005","journal-title":"Clin. Exp. Immunol."},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0210","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.phrp.2014.04.008","article-title":"Frequencies of CD4+ T regulatory cells and their CD25(high) and FoxP3(high) subsets augment in peripheral blood of patients with acute and chronic brucellosis","volume":"5","author":"Bahador","year":"2014","journal-title":"Osong Publ. Health Res. Perspect."},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0215","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1161\/HYPERTENSIONAHA.114.03512","article-title":"Female spontaneously hypertensive rats have a compensatory increase in renal regulatory T cells in response to elevations in blood pressure","volume":"64","author":"Tipton","year":"2014","journal-title":"Hypertension."},{"issue":"17\u201318","key":"10.1016\/j.clim.2023.109244_bb0220","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1089\/hum.2021.024","article-title":"Regulatory T cells and diabetes mellitus","volume":"32","author":"Qin","year":"2021","journal-title":"Hum. Gene Ther."},{"issue":"2","key":"10.1016\/j.clim.2023.109244_bb0225","first-page":"R284","article-title":"Adipose cell size: importance in health and disease","volume":"315","author":"Stenkula","year":"2018","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"issue":"12","key":"10.1016\/j.clim.2023.109244_bb0230","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.autrev.2011.05.002","article-title":"Effects of vitamin D on the peripheral adaptive immune system: a review","volume":"10","author":"Peelen","year":"2011","journal-title":"Autoimmun. Rev."},{"issue":"APR","key":"10.1016\/j.clim.2023.109244_bb0235","doi-asserted-by":"crossref","first-page":"448","DOI":"10.3389\/fimmu.2017.00448","article-title":"Regulatory T cells and pro-inflammatory responses predominate in children with tuberculosis","volume":"8","author":"Whittaker","year":"2017","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.clim.2023.109244_bb0240","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1084\/jem.20050648","article-title":"The immune paradox of sarcoidosis and regulatory T cells","volume":"203","author":"Miyara","year":"2006","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0245","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1128\/IAI.01128-15","article-title":"Accumulation of regulatory T cells and chronic inflammation in the middle ear in a mouse model of chronic otitis media with effusion induced by combined Eustachian","volume":"84","author":"Hirano","year":"2016","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0250","doi-asserted-by":"crossref","first-page":"19018","DOI":"10.1038\/s41598-020-76038-w","article-title":"Regulatory T cell phenotype and anti-osteoclastogenic function in experimental periodontitis","volume":"10","author":"Alvarez","year":"2020","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0255","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/nm.3432","article-title":"Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis","volume":"20","author":"Komatsu","year":"2014","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.clim.2023.109244_bb0260","article-title":"Pathological conditions re-shape physiological Tregs into pathological Tregs","volume":"3","author":"Yang","year":"2015","journal-title":"Burns Trauma"},{"key":"10.1016\/j.clim.2023.109244_bb0265","article-title":"The role of diverse immune cells in sarcoidosis","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.clim.2023.109244_bb0270","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1161\/ATVBAHA.114.304650","article-title":"Nonclassical patrolling monocyte function in the vasculature","volume":"35","author":"Thomas","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.clim.2023.109244_bb0275","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.clim.2018.09.005","article-title":"Th17 and Treg lymphocytes in obesity and type 2 diabetic patients","volume":"197","author":"Wang","year":"2018","journal-title":"Clin. Immunol. (Orlando, Fla)"},{"issue":"6","key":"10.1016\/j.clim.2023.109244_bb0280","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00005-014-0293-y","article-title":"Heterogeneity in the differentiation and function of CD8+ T cells","volume":"62","author":"Mittr\u00fccker","year":"2014","journal-title":"Arch. Immunol. Ther. Exp."},{"key":"10.1016\/j.clim.2023.109244_bb0285","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2017.00656","article-title":"Vitamin D counteracts mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFN\u03b3 secretion","volume":"8","author":"Rode","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.clim.2023.109244_bb0290","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.molmet.2015.12.001","article-title":"Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss","volume":"5","author":"Schmitz","year":"2016","journal-title":"Mol. Metab."},{"issue":"April","key":"10.1016\/j.clim.2023.109244_bb0295","first-page":"1","article-title":"Macrophages mediate increased CD8 T cell inflammation during weight loss in formerly obese mice","volume":"11","author":"Surendar","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.clim.2023.109244_bb0300","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.metabol.2017.01.030","article-title":"The short-term and long-term effects of bariatric\/metabolic surgery on subcutaneous adipose tissue inflammation in humans","volume":"70","author":"Hagman","year":"2017","journal-title":"Metabolism."},{"issue":"23","key":"10.1016\/j.clim.2023.109244_bb0305","doi-asserted-by":"crossref","first-page":"5516","DOI":"10.3390\/jcm10235516","article-title":"Impact of bariatric surgery on adipose tissue biology","volume":"10","author":"Osorio-Conles","year":"2021","journal-title":"J. Clin. Med."},{"issue":"5","key":"10.1016\/j.clim.2023.109244_bb0310","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1093\/advances\/nmab011","article-title":"Putting ATM to BED: how adipose tissue macrophages are affected by bariatric surgery, exercise, and dietary fatty acids","volume":"12","author":"Turner","year":"2021","journal-title":"Adv. Nutr."},{"issue":"06","key":"10.1016\/j.clim.2023.109244_bb0315","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1055\/s-0032-1331746","article-title":"Investigations of the anti-inflammatory effects of vitamin D in adipose tissue: results from an in vitro study and a randomized controlled trial","volume":"45","author":"Wamberg","year":"2013","journal-title":"Horm. Metab. Res."},{"issue":"7","key":"10.1016\/j.clim.2023.109244_bb0320","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.ejim.2013.03.005","article-title":"Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels; results from a randomized trial","volume":"24","author":"Wamberg","year":"2013","journal-title":"Eur. J. Intern. Med."},{"issue":"11","key":"10.1016\/j.clim.2023.109244_bb0325","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/s41577-018-0056-9","article-title":"Perivascular macrophages in health and disease","volume":"18","author":"Lapenna","year":"2018","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.clim.2023.109244_bb0330","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.cell.2016.07.047","article-title":"Kidney macrophages: unique position solves a complex problem","volume":"166","author":"Berry","year":"2016","journal-title":"Cell."},{"issue":"8","key":"10.1016\/j.clim.2023.109244_bb0335","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1038\/oby.2008.266","article-title":"Abnormal immune responses in fa\/fa Zucker rats and effects of feeding conjugated linoleic acid","volume":"16","author":"Ruth","year":"2008","journal-title":"Obesity."},{"issue":"9","key":"10.1016\/j.clim.2023.109244_bb0340","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0222313","article-title":"The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: a systematic review","volume":"14","author":"Fisher","year":"2019","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.clim.2023.109244_bb0345","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00394-013-0579-6","article-title":"High-dose cholecalciferol supplementation significantly increases peripheral CD4+ Tregs in healthy adults without negatively affecting the frequency of other immune cells","volume":"53","author":"Prietl","year":"2014","journal-title":"Eur. J. Nutr."},{"issue":"12","key":"10.1016\/j.clim.2023.109244_bb0350","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1111\/j.1365-2222.2009.03357.x","article-title":"The effect of oral steroids with and without vitamin D3 on early efficacy of immunotherapy in asthmatic children","volume":"39","author":"Majak","year":"2009","journal-title":"Clin. Exp. Allergy"},{"issue":"2","key":"10.1016\/j.clim.2023.109244_bb0355","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/all.12278","article-title":"Vitamin D as an adjunct to subcutaneous allergen immunotherapy in asthmatic children sensitized to house dust mite","volume":"69","author":"Baris","year":"2014","journal-title":"Allergy."},{"key":"10.1016\/j.clim.2023.109244_bb0360","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.imbio.2012.05.010","article-title":"Dynamic changes of the Th17\/Tc17 and regulatory T cell populations interfere in the experimental autoimmune diabetes pathogenesis","volume":"218","author":"Navarro","year":"2013","journal-title":"Immunobiology."},{"key":"10.1016\/j.clim.2023.109244_bb0365","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2021-066452","article-title":"Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial","author":"Hahn","year":"2022","journal-title":"BMJ."},{"issue":"8","key":"10.1016\/j.clim.2023.109244_bb0370","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1001\/jama.2019.11889","article-title":"Effect of high-dose vitamin D supplementation on volumetric bone density and bone strength","volume":"322","author":"Burt","year":"2019","journal-title":"JAMA."}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661623000232?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661623000232?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T04:06:34Z","timestamp":1738901194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521661623000232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":74,"alternative-id":["S1521661623000232"],"URL":"https:\/\/doi.org\/10.1016\/j.clim.2023.109244","relation":{},"ISSN":["1521-6616"],"issn-type":[{"value":"1521-6616","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In obese hypertensives cholecalciferol inhibits circulating TH17 cells but not macrophage infiltration on adipose tissue","name":"articletitle","label":"Article Title"},{"value":"Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clim.2023.109244","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"109244"}}