{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:00:05Z","timestamp":1758052805470,"version":"3.44.0"},"reference-count":12,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.clinbiochem.2007.11.006","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T15:39:15Z","timestamp":1196177955000},"page":"174-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Distinct association of SLC19A1 polymorphism \u2212 43T>C with red cell folate levels and of MTHFR polymorphism 677C>T with plasma folate levels"],"prefix":"10.1016","volume":"41","author":[{"given":"Anthoula","family":"Chatzikyriakidou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos V.","family":"Vakalis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Kolaitis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Kolios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina K.","family":"Naka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lampros K.","family":"Michalis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Georgiou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinbiochem.2007.11.006_bib1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.18388\/abp.2000_3992","article-title":"Cellular aspects of folate and antifolate membrane transport","volume":"47","author":"Brzezinska","year":"2000","journal-title":"Acta Biochim Pol"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib2","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0021-9150(03)00098-4","article-title":"Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid","volume":"168","author":"Brilakis","year":"2003","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0049-3848(03)00341-4","article-title":"The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case\u2013control study","volume":"110","author":"Klerk","year":"2003","journal-title":"Thromb Res"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/ng0595-111","article-title":"A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase","volume":"10","author":"Frosst","year":"1995","journal-title":"Nat Genet"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib5","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1097\/00019501-200112000-00010","article-title":"Relatively low red cell folate levels and acute coronary syndromes","volume":"12","author":"Michalis","year":"2001","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib6","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1007\/s00296-007-0339-0","article-title":"Transcription regulatory polymorphism \u221243T>C in the 5\u2032-flanking region of SLC19A1 gene could affect rheumatoid arthritis patient response to methotrexate therapy","volume":"27","author":"Chatzikyriakidou","year":"2007","journal-title":"Rheum Int"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0049-3848(01)00352-8","article-title":"Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases","volume":"104","author":"Zhang","year":"2001","journal-title":"Thromb Res"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1006\/mgme.2000.2993","article-title":"Polymorphisms in the CBS gene associated with decreased risk of coronary artery disease and increased responsiveness to total homocysteine lowering by folic acid","volume":"70","author":"Kruger","year":"2000","journal-title":"Mol Gen Metab"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1477-9560-3-13","article-title":"Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B12 in patients with retinal vein occlusion","volume":"3","author":"Terazzi","year":"2005","journal-title":"Thromb J"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib10","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.clnu.2004.07.019","article-title":"Distribution of 5,10-methylenetetrahydrofolate reductase (C667T) polymorphism and its association with red blood cell 5-methyltetrahydrofolate in the healthy Iranians","volume":"24","author":"Golbahar","year":"2005","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib11","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/biof.5520100230","article-title":"Folate status and neural tube defects","volume":"10","author":"Molloy","year":"1999","journal-title":"Biofactors"},{"key":"10.1016\/j.clinbiochem.2007.11.006_bib12","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/S0140-6736(96)12049-3","article-title":"Thermolabile variant 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations","volume":"349","author":"Molloy","year":"1997","journal-title":"Lancet"}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912007004432?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912007004432?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:28:14Z","timestamp":1757863694000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912007004432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S0009912007004432"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2007.11.006","relation":{},"ISSN":["0009-9120"],"issn-type":[{"type":"print","value":"0009-9120"}],"subject":[],"published":{"date-parts":[[2008,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct association of SLC19A1 polymorphism \u221243T>C with red cell folate levels and of MTHFR polymorphism 677C>T with plasma folate levels","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2007.11.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}