{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:02:16Z","timestamp":1758052936782,"version":"3.44.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.clinbiochem.2007.12.009","type":"journal-article","created":{"date-parts":[[2007,12,28]],"date-time":"2007-12-28T10:51:33Z","timestamp":1198839093000},"page":"368-374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Circulating P-, L- and E-selectins in pseudoxanthoma elasticum patients"],"prefix":"10.1016","volume":"41","author":[{"given":"Christian","family":"G\u00f6tting","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Adam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"Szliska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Knut","family":"Kleesiek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinbiochem.2007.12.009_bib1","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1056\/NEJM199310213291705","article-title":"Brief report: occult pseudoxanthoma elasticum in patients with premature cardiovascular disease","volume":"329","author":"Lebwohl","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0190-9622(08)81894-4","article-title":"Classification of pseudoxanthoma elasticum: report of a consensus conference","volume":"30","author":"Lebwohl","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib3","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/labinvest.3780444","article-title":"MRP6 (ABCC6) detection in normal human tissues and tumors","volume":"82","author":"Scheffer","year":"2002","journal-title":"Lab Invest"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/cbf.653","article-title":"Proteoglycan alterations in skin fibroblast cultures from patients affected with pseudoxanthoma elasticum","volume":"14","author":"Passi","year":"1996","journal-title":"Cell Biochem Funct"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib5","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1007\/s00109-005-0693-x","article-title":"Elevated xylosyltransferase I activities in pseudoxanthoma elasticum (PXE) patients as a marker of stimulated proteoglycan biosynthesis","volume":"83","author":"G\u00f6tting","year":"2005","journal-title":"J Mol Med"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib6","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/path.1867","article-title":"Oxidative stress in fibroblasts from patients with pseudoxanthoma elasticum: possible role in the pathogenesis of clinical manifestations","volume":"208","author":"Pasquali-Ronchetti","year":"2006","journal-title":"J Pathol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib7","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1373\/clinchem.2007.088211","article-title":"Pseudoxanthoma elasticum: genetic variations in antioxidant genes are risk factors for early disease onset","volume":"53","author":"Zarbock","year":"2007","journal-title":"Clin Chem"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib8","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1373\/clinchem.2005.059253","article-title":"Role of serum fetuin-A, a major inhibitor of systemic calcification, in pseudoxanthoma elasticum","volume":"52","author":"Hendig","year":"2006","journal-title":"Clin Chem"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib9","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1373\/clinchem.2006.083675","article-title":"SPP1 promoter polymorphisms: identification of the first modifier gene for pseudoxanthoma elasticum","volume":"53","author":"Hendig","year":"2007","journal-title":"Clin Chem"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib10","doi-asserted-by":"crossref","first-page":"ix","DOI":"10.1111\/j.0022-202X.2004.22350.x","article-title":"Pseudoxanthoma elasticum\u2014a connective tissue disease or a metabolic disorder at the genome\/environment interface?","volume":"122","author":"Uitto","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib11","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1515\/CCLM.2004.082","article-title":"The emerging value of P-selectin as a disease marker","volume":"42","author":"Kappelmayer","year":"2004","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib12","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1749-6632.1992.tb51633.x","article-title":"Soluble forms of vascular adhesion molecules, E-selectin, ICAM-1, and VCAM-1: pathological significance","volume":"667","author":"Gearing","year":"1992","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib13","doi-asserted-by":"crossref","first-page":"4219","DOI":"10.1161\/01.CIR.96.12.4219","article-title":"Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study","volume":"96","author":"Hwang","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib14","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1080\/03014460110048530","article-title":"The relationship of soluble ICAM-1, VCAM-1, P-selectin and E-selectin to cardiovascular disease risk factors in healthy men and women","volume":"28","author":"Demerath","year":"2001","journal-title":"Ann Hum Biol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0021-9150(02)00234-4","article-title":"Soluble intercellular adhesion molecule-1 is related to endothelial vasodilatory function in healthy individuals","volume":"165","author":"Holmlund","year":"2002","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib16","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/s001250050930","article-title":"Soluble vascular cell adhesion molecule-1 and E-selectin levels in relation to vascular risk factors and to E-selectin genotype in the first degree relatives of NIDDM patients and in NIDDM patients","volume":"41","author":"Bannan","year":"1998","journal-title":"Diabetologia"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib17","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1182\/blood.V84.4.1249.1249","article-title":"High levels of the shed form of L-selectin are present in patients with acute leukemia and inhibit blast cell adhesion to activated endothelium","volume":"84","author":"Spertini","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib18","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.2337\/diab.41.12.1668","article-title":"Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM","volume":"41","author":"Lampeter","year":"1992","journal-title":"Diabetes"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0140-6736(94)92995-5","article-title":"Role of selectins in development of adult respiratory distress syndrome","volume":"344","author":"Donnelly","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib20","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/0167-5699(93)90267-O","article-title":"Circulating adhesion molecules in disease","volume":"14","author":"Gearing","year":"1993","journal-title":"Immunol Today"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib21","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1083\/jcb.119.1.229","article-title":"Soluble L-selectin is present in human plasma at high levels and retains functional activity","volume":"119","author":"Schleiffenbaum","year":"1992","journal-title":"J Cell Biol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1600-0609.1993.tb01603.x","article-title":"Correlation between serum level of soluble L-selectin and leukocyte count in chronic myeloid and lymphocytic leukemia and during bone marrow transplantation","volume":"51","author":"Zetterberg","year":"1993","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib23","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1055\/s-2007-979114","article-title":"Putative role of adhesion molecules in metabolic disorders","volume":"29","author":"Wagner","year":"1997","journal-title":"Horm Metab Res"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib24","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s001250050888","article-title":"Increased expression of selectins in kidneys of patients with diabetic nephropathy","volume":"41","author":"Hirata","year":"1998","journal-title":"Diabetologia"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib25","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/humu.9444","article-title":"Mutational analysis of the ABCC6 gene and the proximal ABCC6 gene promoter in German patients with pseudoxanthoma elasticum (PXE)","volume":"27","author":"Schulz","year":"2006","journal-title":"Hum Mutat"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib26","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1353\/hub.2005.0054","article-title":"Novel mutations in the ABCC6 gene of German patients with pseudoxanthoma elasticum","volume":"77","author":"Schulz","year":"2005","journal-title":"Hum Biol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib27","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s00109-004-0588-2","article-title":"New ABCC6 gene mutations in German pseudoxanthoma elasticum patients","volume":"83","author":"Hendig","year":"2005","journal-title":"J Mol Med"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib28","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1373\/49.9.1544","article-title":"Age- and sex-related reference values for serum adhesion molecule concentrations in healthy individuals: intercellular adhesion molecule-1 and E-, P-, and L-selectin","volume":"49","author":"Ponthieux","year":"2003","journal-title":"Clin Chem"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib29","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.2307\/2533494","article-title":"From genotypes to genes: doubling the sample size","volume":"53","author":"Sasieni","year":"1997","journal-title":"Biometrics"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib30","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/ng1706","article-title":"Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies","volume":"38","author":"Skol","year":"2006","journal-title":"Nat Genet"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib31","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/0197-2456(90)90005-M","article-title":"Power and sample size calculations. A review and computer program","volume":"11","author":"Dupont","year":"1990","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib32","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/S0039-6257(03)00053-5","article-title":". Pseudoxanthoma elasticum: a clinical, histopathological, and molecular update","volume":"48","author":"Hu","year":"2003","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib33","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/j.0022-202X.2004.22312.x","article-title":"Novel ABCC6 mutations in pseudoxanthoma elasticum","volume":"122","author":"Chassaing","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib34","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1080\/01926230290166724","article-title":"Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification","volume":"30","author":"Kohen","year":"2002","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib35","doi-asserted-by":"crossref","first-page":"25869","DOI":"10.1074\/jbc.274.36.25869","article-title":"Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1","volume":"274","author":"Wenk","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib36","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/380720a0","article-title":"Neutrophil rolling altered by inhibition of L-selectin shedding in vitro","volume":"380","author":"Walcheck","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib37","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0925-4439(00)00007-7","article-title":"Abnormal phenotype of in vitro dermal fibroblasts from patients with pseudoxanthoma elasticum (PXE)","volume":"1501","author":"Quaglino","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib38","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00004872-199816010-00008","article-title":"Progressive vascular damage in hypertension is associated with increased levels of circulating P-selectin","volume":"16","author":"Verhaar","year":"1998","journal-title":"J Hypertens"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib39","doi-asserted-by":"crossref","first-page":"189","DOI":"10.32604\/biocell.2003.27.189","article-title":"Proteoglycans production by aortic vascular smooth muscle cells from hypertensive rats","volume":"27","author":"Risler","year":"2003","journal-title":"Biocell"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib40","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1172\/JCI1509","article-title":"Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents","volume":"101","author":"Koenig","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib41","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1373\/49.3.380","article-title":"Anomalous structure of urinary glycosaminoglycans in patients with pseudoxanthoma elasticum","volume":"49","author":"Maccari","year":"2003","journal-title":"Clin Chem"},{"key":"10.1016\/j.clinbiochem.2007.12.009_bib42","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1007\/s00018-007-7069-z","article-title":"Human xylosyltransferases in health and disease","volume":"64","author":"G\u00f6tting","year":"2007","journal-title":"Cell Mol Life Sci"}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912007004894?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912007004894?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:27:01Z","timestamp":1757863621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912007004894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0009912007004894"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2007.12.009","relation":{},"ISSN":["0009-9120"],"issn-type":[{"type":"print","value":"0009-9120"}],"subject":[],"published":{"date-parts":[[2008,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Circulating P-, L- and E-selectins in pseudoxanthoma elasticum patients","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2007.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}