{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T19:59:23Z","timestamp":1758052763835,"version":"3.44.0"},"reference-count":12,"publisher":"Elsevier BV","issue":"10-11","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["PS\/03\/4","PS\/03\/9"],"award-info":[{"award-number":["PS\/03\/4","PS\/03\/9"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.clinbiochem.2008.03.015","type":"journal-article","created":{"date-parts":[[2008,4,12]],"date-time":"2008-04-12T12:48:03Z","timestamp":1208004483000},"page":"914-916","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?"],"prefix":"10.1016","volume":"41","author":[{"given":"Gloria","family":"Galimberti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Conti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Zini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Fenaroli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Isella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Facheris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vittoria","family":"Perlangeli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Antolini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"DeFilippi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Ferrarese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinbiochem.2008.03.015_bib1","first-page":"389","article-title":"Causes and consequences of hyperhomocysteinemia","volume":"67","author":"Pietrzik","year":"1997","journal-title":"Int J Vitam Nutr Res"},{"issue":"1","key":"10.1016\/j.clinbiochem.2008.03.015_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s10545-006-0106-5","article-title":"Homocysteine metabolism, hyperhomocysteinemia and vascular disease: an overview","volume":"29","author":"Castro","year":"2006","journal-title":"J Inherit Metab Dis."},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib3","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/ajcn\/85.2.511","article-title":"Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study On Aging","volume":"85","author":"Haan","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib4","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1093\/ajcn\/82.3.636","article-title":"Homocysteine and folate as risk factors for dementia and Alzheimer disease","volume":"82","author":"Ravaglia","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib5","doi-asserted-by":"crossref","first-page":"393","DOI":"10.3233\/JAD-2006-9404","article-title":"Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?","volume":"9","author":"Seshadri","year":"2006","journal-title":"J Alzh Dis"},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib6","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jns.2007.01.039","article-title":"Vascular oxidative stress in Alzheimer disease","volume":"257","author":"Zhu","year":"2007","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1191\/1358863x02vm407ra","article-title":"Post-methionine load homocysteine determination for the diagnosis hyperhomocysteinemia and efficacy of homocysteine lowering treatment regimens","volume":"7","author":"van der Griend","year":"2002","journal-title":"Vasc Med"},{"issue":"7","key":"10.1016\/j.clinbiochem.2008.03.015_bib8","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib9","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1258\/0004563001899915","article-title":"Total homocysteine measurement in clinical practice","volume":"37","author":"Rasmussen","year":"2000","journal-title":"Ann Clin Biochem"},{"issue":"9","key":"10.1016\/j.clinbiochem.2008.03.015_bib10","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1515\/CCLM.2004.207","article-title":"Evaluation of a shorter methionine loading test","volume":"42","author":"de Jonge","year":"2004","journal-title":"Clin Chem Lab Med"},{"issue":"10","key":"10.1016\/j.clinbiochem.2008.03.015_bib11","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.clinbiochem.2006.07.005","article-title":"Total plasma homocysteine values among elderly subjects: findings from the Maracaibo Aging Study","volume":"39","author":"Molero","year":"2006","journal-title":"Clin Biochem"},{"key":"10.1016\/j.clinbiochem.2008.03.015_bib12","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1093\/ajcn\/82.4.806","article-title":"Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials","volume":"82","author":"Homocysteine Lowering Trialists' Collaboration","year":"2005","journal-title":"Am J Clin Nutr"}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912008001513?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912008001513?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:28:20Z","timestamp":1757863700000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912008001513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":12,"journal-issue":{"issue":"10-11","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S0009912008001513"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2008.03.015","relation":{},"ISSN":["0009-9120"],"issn-type":[{"type":"print","value":"0009-9120"}],"subject":[],"published":{"date-parts":[[2008,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2008.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}