{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:16:07Z","timestamp":1786986967767,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","issue":"7-8","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.clinbiochem.2013.02.006","type":"journal-article","created":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T19:46:24Z","timestamp":1361821584000},"page":"603-611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Transcript levels of major MMPs and ADAMTS-4 in relation to the clinicopathological profile of patients with tuberculous intervertebral discs and healthy controls"],"prefix":"10.1016","volume":"46","author":[{"given":"Chunxiang","family":"Xiong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinli","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengming","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0005","doi-asserted-by":"crossref","first-page":"138","DOI":"10.4103\/0019-5413.93673","article-title":"Efficacy of directly observed treatment short-course intermittent regimen in spinal tuberculosis","volume":"46","author":"Valsalan","year":"2012","journal-title":"Indian J Orthop"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0010","first-page":"575","article-title":"Anterior radical debridement and reconstruction using titanium mesh cage for the surgical treatment of thoracic and thoracolumbar spinal tuberculosis: minimium five-year follow-up","volume":"21","author":"Wang","year":"2011","journal-title":"Turk Neurosurg"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0015","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1179\/2045772311Y.0000000023","article-title":"Spinal tuberculosis: a review","volume":"34","author":"Garg","year":"2011","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0020","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4103\/0971-3026.73544","article-title":"Role of magnetic resonance diffusion imaging and apparent diffusion coefficient values in the evaluation of spinal tuberculosis in Indian patients","volume":"20","author":"Palle","year":"2010","journal-title":"Indian J Radiol Imaging"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0025","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1600-0765.2009.01218.x","article-title":"Enamel matrix derivative induces the expression of tissue inhibitor of matrix metalloproteinase-3 in human gingival fibroblasts via extracellular signal-regulated kinase","volume":"45","author":"Zeldich","year":"2010","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0030","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.1002\/jcb.23298","article-title":"ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis","volume":"112","author":"Verma","year":"2011","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0035","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1136\/ard.2007.079574","article-title":"Differential Toll-like receptor-dependent collagenase expression in chondrocytes","volume":"67","author":"Zhang","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0040","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.4161\/cc.8.22.9956","article-title":"Protective roles of matrix metalloproteinases: from mouse models to human cancer","volume":"8","author":"L\u00f3pez-Ot\u00edn","year":"2009","journal-title":"Cell Cycle"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0045","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s12291-010-0103-1","article-title":"Role of plasma MMP 9 levels in the pathogenesis of chronic pancreatitis","volume":"26","author":"Venkateshwari","year":"2011","journal-title":"Indian J Clin Biochem"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0050","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ijpharm.2011.02.060","article-title":"Liposomal targeting of glucocorticoids to the inflamed synovium inhibits cartilage matrix destruction during murine antigen-induced arthritis","volume":"416","author":"Hofkens","year":"2011","journal-title":"Int J Pharm"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0055","doi-asserted-by":"crossref","first-page":"320","DOI":"10.22203\/eCM.v023a25","article-title":"Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells","volume":"23","author":"Boeuf","year":"2012","journal-title":"Eur Cell Mater"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0060","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/jor.21507","article-title":"Alterations of ADAMTSs and TIMP-3 in human nucleus pulposus cells subjected to compressive load: implications in the pathogenesis of human intervertebral disc degeneration","volume":"30","author":"Huang","year":"2012","journal-title":"J Orthop Res"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0065","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1007\/s00402-012-1506-7","article-title":"Sequencing-based detection of drug-resistant Mycobacterium tuberculosis in patients with spinal tuberculosis","volume":"132","author":"Si","year":"2012","journal-title":"Arch Orthop Trauma Surg"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0070","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1556\/AMicr.57.2010.2.5","article-title":"Pattern of matrix metalloproteinases-9, P53 and BCL-2 proteins in Egyptian patients with pulmonary Mycobacterium tuberculosis","volume":"57","author":"El-Masry","year":"2010","journal-title":"Acta Microbiol Immunol Hung"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0075","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1172\/JCI45666","article-title":"MMP-1 drives immunopathology in human tuberculosis and transgenic mice","volume":"121","author":"Elkington","year":"2011","journal-title":"J Clin Invest"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0080","doi-asserted-by":"crossref","first-page":"6492","DOI":"10.4049\/jimmunol.0903811","article-title":"Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks","volume":"184","author":"Green","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0085","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1517\/17460441.2011.560936","article-title":"New opportunities in drug design of metalloproteinase inhibitors: combination between structure\u2013function experimental approaches and systems biology","volume":"6","author":"Sela-Passwell","year":"2011","journal-title":"Expert Opin Drug Discov"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0090","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1111\/j.1742-4658.2011.08244.x","article-title":"Matrix metalloproteinase proteolysis of the mycobacterial HSP65 protein as a potential source of immunogenic peptides in human tuberculosis","volume":"278","author":"Shiryaev","year":"2011","journal-title":"FEBS J"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0095","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000163064","article-title":"Mycobacterium tuberculosis effects on fibroblast collagen metabolism","volume":"77","author":"Gonz\u00e1lez-Avila","year":"2009","journal-title":"Respiration"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0100","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s00586-010-1573-9","article-title":"Transcript levels of major MMPs and ADAMTS-4 in relation to the clinicopathological profile of patients with lumbar disc herniation","volume":"20","author":"Tsarouhas","year":"2011","journal-title":"Eur Spine J"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0105","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1756-185X.2011.01656.x","article-title":"Interleukin-6 upregulates expression of ADAMTS-4 in fibroblast-like synoviocytes from patients with rheumatoid arthritis","volume":"15","author":"Mimata","year":"2012","journal-title":"Int J Rheum Dis"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0110","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1002\/art.23638","article-title":"Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis","volume":"58","author":"Kadri","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0115","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1002\/art.22128","article-title":"Role of aggrecanase 1 in lyme arthritis","volume":"54","author":"Behera","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0120","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1002\/jor.21417","article-title":"Differential effects of nicotine and tobacco smoke condensate on human annulus fibrosus cell metabolism","volume":"29","author":"Vo","year":"2011","journal-title":"J Orthop Res"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0125","doi-asserted-by":"crossref","first-page":"R215","DOI":"10.1186\/ar3548","article-title":"Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration","volume":"13","author":"Erwin","year":"2011","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0130","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0736-0266(02)00141-9","article-title":"IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells","volume":"21","author":"Tsuzaki","year":"2003","journal-title":"J Orthop Res"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0135","first-page":"200","article-title":"Variety of ESR and C-reactive protein levels during perioperative period in spinal tuberculosis","volume":"23","author":"Guo","year":"2010","journal-title":"Zhongguo Gu Shang"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0140","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/mi.2011.14","article-title":"Macrophages and control of granulomatous inflammation in tuberculosis","volume":"4","author":"Flynn","year":"2011","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.clinbiochem.2013.02.006_bb0145","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.archoralbio.2011.05.005","article-title":"Interleukin-1 beta affects cyclooxygenase-2 expression and cartilage metabolism in mandibular condyle","volume":"56","author":"Tanimoto","year":"2011","journal-title":"Arch Oral Biol"}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912013000659?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912013000659?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:39:59Z","timestamp":1757864399000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912013000659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":29,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0009912013000659"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2013.02.006","relation":{},"ISSN":["0009-9120"],"issn-type":[{"value":"0009-9120","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcript levels of major MMPs and ADAMTS-4 in relation to the clinicopathological profile of patients with tuberculous intervertebral discs and healthy controls","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2013.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}