{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T20:56:35Z","timestamp":1762808195360,"version":"3.44.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007048","name":"Mayo Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007048","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.clinbiochem.2013.05.041","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T00:50:00Z","timestamp":1368665400000},"page":"1430-1435","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Measurement of urinary TGF-\u03b21 in patients with diabetes mellitus and normal controls"],"prefix":"10.1016","volume":"46","author":[{"given":"Mykola V.","family":"Tsapenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemary E.","family":"Nwoko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy M.","family":"Borland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolay V.","family":"Voskoboev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Pflueger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew D.","family":"Rule","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Lieske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.clinbiochem.2013.05.041_bb0005","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.2337\/diabetes.51.12.3577","article-title":"Cellular basis of diabetic nephropathy: II. The transforming growth factor-beta system and diabetic nephropathy lesions in type 1 diabetes","volume":"51","author":"Huang","year":"2002","journal-title":"Diabetes"},{"issue":"12","key":"10.1016\/j.clinbiochem.2013.05.041_bb0010","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1093\/ndt\/17.12.2145","article-title":"Transforming growth factor-beta(1) in the kidney and urine of patients with glomerular disease and proteinuria","volume":"17","author":"Goumenos","year":"2002","journal-title":"Nephrol Dial Transplant"},{"issue":"9","key":"10.1016\/j.clinbiochem.2013.05.041_bb0015","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/sj.jhh.1001465","article-title":"Relationship between transforming growth factor beta1 and progression of hypertensive renal disease","volume":"16","author":"Scaglione","year":"2002","journal-title":"J Hum Hypertens"},{"issue":"6","key":"10.1016\/j.clinbiochem.2013.05.041_bb0020","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1046\/j.1523-1755.2002.00380.x","article-title":"Proximal tubular cells promote fibrogenesis by TGF-beta1-mediated induction of peritubular myofibroblasts","volume":"61","author":"Abbate","year":"2002","journal-title":"Kidney Int"},{"issue":"10","key":"10.1016\/j.clinbiochem.2013.05.041_bb0025","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1172\/JCI200319270","article-title":"Targeted disruption of TGF-beta1\/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction","volume":"112","author":"Sato","year":"2003","journal-title":"J Clin Invest"},{"issue":"3","key":"10.1016\/j.clinbiochem.2013.05.041_bb0030","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/dmrr.1068","article-title":"Urinary biomarkers involved in type 2 diabetes: a review","volume":"26","author":"Matheson","year":"2010","journal-title":"Diabetes Metab Res Rev"},{"issue":"1","key":"10.1016\/j.clinbiochem.2013.05.041_bb0035","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0022-1759(93)90254-5","article-title":"Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor beta 1","volume":"158","author":"Danielpour","year":"1993","journal-title":"J Immunol Methods"},{"issue":"4","key":"10.1016\/j.clinbiochem.2013.05.041_bb0040","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/ajcp\/100.4.419","article-title":"Protein\u2013osmolality ratio for the quantitative assessment of proteinuria from a random urinalysis sample","volume":"100","author":"Wilson","year":"1993","journal-title":"Am J Clin Pathol"},{"issue":"11\u201312","key":"10.1016\/j.clinbiochem.2013.05.041_bb0045","first-page":"1027","article-title":"Urine TGF-beta1 assay validation: spinning down urine samples could diminish TGF-beta1 signal","volume":"57","author":"Pavlov","year":"2011","journal-title":"Clin Lab"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.05.041_bb0050","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00467-010-1677-9","article-title":"Urinary transforming growth factor beta-1 as a marker of renal dysfunction in sickle cell disease","volume":"26","author":"Mohtat","year":"2011","journal-title":"Pediatr Nephrol"},{"issue":"11","key":"10.1016\/j.clinbiochem.2013.05.041_bb0055","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1161\/01.CIR.0000158483.13093.9D","article-title":"Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation","volume":"111","author":"Dandona","year":"2005","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.clinbiochem.2013.05.041_bb0060","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s11892-004-0055-z","article-title":"Transforming growth factor-beta: a clinical target for the treatment of diabetic nephropathy","volume":"4","author":"McGowan","year":"2004","journal-title":"Curr Diab Rep"},{"issue":"7","key":"10.1016\/j.clinbiochem.2013.05.041_bb0065","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1093\/ndt\/gfh837","article-title":"Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy","volume":"20","author":"Chen","year":"2005","journal-title":"Nephrol Dial Transplant"},{"issue":"3","key":"10.1016\/j.clinbiochem.2013.05.041_bb0070","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/ki.2010.109","article-title":"Regulation of transforming growth factor-beta1 by insulin in prediabetic African Americans","volume":"78","author":"Huan","year":"2010","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.05.041_bb0075","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1046\/j.1523-1755.2001.059002673.x","article-title":"Glycated albumin stimulates TGF-beta 1 production and protein kinase C activity in glomerular endothelial cells","volume":"59","author":"Chen","year":"2001","journal-title":"Kidney Int"},{"issue":"5","key":"10.1016\/j.clinbiochem.2013.05.041_bb0080","doi-asserted-by":"crossref","first-page":"854","DOI":"10.2337\/diab.46.5.854","article-title":"Increased renal production of transforming growth factor-beta1 in patients with type II diabetes","volume":"46","author":"Sharma","year":"1997","journal-title":"Diabetes"},{"issue":"6","key":"10.1016\/j.clinbiochem.2013.05.041_bb0085","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1053\/S0270-9295(03)00132-3","article-title":"Diabetic nephropathy and transforming growth factor-beta: transforming our view of glomerulosclerosis and fibrosis build-up","volume":"23","author":"Chen","year":"2003","journal-title":"Semin Nephrol"},{"issue":"3\u20134","key":"10.1016\/j.clinbiochem.2013.05.041_bb0090","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1081\/JDI-100104730","article-title":"The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy","volume":"23","author":"Chen","year":"2001","journal-title":"Ren Fail"},{"issue":"6","key":"10.1016\/j.clinbiochem.2013.05.041_bb0095","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1016\/j.ajpath.2011.02.039","article-title":"Murphy-Ullrich JE. Blockade of TSP1-dependent TGF-beta activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy","volume":"178","author":"Lu","year":"2011","journal-title":"Am J Pathol"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.05.041_bb0100","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1159\/000093178","article-title":"Accurate measurement and clinical significance of urinary transforming growth factor-beta1","volume":"26","author":"Tsakas","year":"2006","journal-title":"Am J Nephrol"},{"issue":"2 Suppl. 2","key":"10.1016\/j.clinbiochem.2013.05.041_bb0105","first-page":"S2-54-9","article-title":"Prevalence of diabetes mellitus and correlation of urinary transforming growth factor-beta1 with blood hemoglobin A1C in the Atascosa Diabetes Study","volume":"18","author":"Riojas","year":"2008","journal-title":"Ethn Dis"},{"issue":"9","key":"10.1016\/j.clinbiochem.2013.05.041_bb0110","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.biopha.2009.02.002","article-title":"Urinary TGF-beta1 as an indicator of antiproteinuric response to angiotensin II receptor blocker in proteinuric renal diseases","volume":"63","author":"Park","year":"2009","journal-title":"Biomed Pharmacother"},{"issue":"12","key":"10.1016\/j.clinbiochem.2013.05.041_bb0115","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1590\/S0100-879X1999001200011","article-title":"Transforming growth factor beta activity in urine of patients with type 2 diabetes and diabetic nephropathy","volume":"32","author":"Rivarola","year":"1999","journal-title":"Braz J Med Biol Res"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.05.041_bb0120","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.diabres.2004.01.007","article-title":"Elevation of urinary betaig-h3, transforming growth factor-beta-induced protein in patients with type 2 diabetes and nephropathy","volume":"65","author":"Ha","year":"2004","journal-title":"Diabetes Res Clin Pract"},{"issue":"11\u201312","key":"10.1016\/j.clinbiochem.2013.05.041_bb0125","first-page":"1027","article-title":"Urine TGF- beta1 assay validation: spinning down urine samples could diminish TGF-beta1 signal","volume":"57","author":"Pavlov","year":"2011","journal-title":"Clin Lab"},{"issue":"7","key":"10.1016\/j.clinbiochem.2013.05.041_bb0130","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0895-7061(03)00847-1","article-title":"Association between transforming growth factor-beta and hypertension","volume":"16","author":"Lijnen","year":"2003","journal-title":"Am J Hypertens"},{"issue":"9","key":"10.1016\/j.clinbiochem.2013.05.041_bb0135","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1093\/ndt\/gfn159","article-title":"Transforming growth factor-beta1 is associated with kidney damage in patients with essential hypertension: renoprotective effect of ACE inhibitor and\/or angiotensin II receptor blocker","volume":"23","author":"Zhu","year":"2008","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"10.1016\/j.clinbiochem.2013.05.041_bb0140","first-page":"365","article-title":"Effects of losartan on urinary secretion of extracellular matrix and their modulators in type 2 diabetes mellitus patients with microalbuminuria","volume":"29","author":"Woo","year":"2006","journal-title":"Clin Invest Med"}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912013002373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912013002373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:45:34Z","timestamp":1757864734000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912013002373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":28,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0009912013002373"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2013.05.041","relation":{},"ISSN":["0009-9120"],"issn-type":[{"type":"print","value":"0009-9120"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Measurement of urinary TGF-\u03b21 in patients with diabetes mellitus and normal controls","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2013.05.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}