{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T12:45:51Z","timestamp":1778417151810,"version":"3.51.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.clinbiochem.2013.06.023","type":"journal-article","created":{"date-parts":[[2013,7,2]],"date-time":"2013-07-02T12:01:59Z","timestamp":1372766519000},"page":"1405-1409","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["The relationship between intact PTH and biointact PTH (1\u201384) with bone and mineral metabolism in pre-dialysis chronic kidney disease (CKD)"],"prefix":"10.1016","volume":"46","author":[{"given":"D.","family":"O'Flaherty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sankaralingam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Scully","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Manghat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Goldsmith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Hampson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.clinbiochem.2013.06.023_bb0005","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s10157-006-0432-9","article-title":"Regulation of parathyroid function in chronic kidney disease (CKD)","volume":"10","author":"Fukagawa","year":"2006","journal-title":"Clin Exp Nephrol"},{"key":"10.1016\/j.clinbiochem.2013.06.023_bb0010","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1046\/j.1523-1755.1999.07304.x","article-title":"Pathogenesis of secondary hyperparathyroidism","volume":"73","author":"Slatopolsky","year":"1999","journal-title":"Kidney Int Suppl"},{"issue":"4 Suppl. 3","key":"10.1016\/j.clinbiochem.2013.06.023_bb0015","first-page":"1","article-title":"K\/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. National Kidney Foundation","volume":"42","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.clinbiochem.2013.06.023_bb0020","first-page":"S1","article-title":"KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD\u2013MBD)","volume":"113","author":"Moe","year":"2009","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.clinbiochem.2013.06.023_bb0025","article-title":"COSMOS: the dialysisscenario of CKD\u2013MBD in Europe","author":"Fern\u00e1ndez-Mart\u00edn","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"11","key":"10.1016\/j.clinbiochem.2013.06.023_bb0030","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1038\/sj.ki.5000414","article-title":"Definition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)","volume":"69","author":"Moe","year":"2006","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.06.023_bb0035","doi-asserted-by":"crossref","first-page":"299","DOI":"10.2215\/CJN.09580911","article-title":"PTH \u2014 a particularly tricky hormone: why measure it at all in kidney patients?","volume":"8","author":"Garrett","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"4","key":"10.1016\/j.clinbiochem.2013.06.023_bb0040","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/clinchem\/44.4.805","article-title":"A non-(1\u201384) circulating parathyroid hormone (PTH) fragment interferes significantly with intact PTH commercial assay measurements in uremic samples","volume":"44","author":"Lepage","year":"1998","journal-title":"Clin Chem"},{"issue":"5","key":"10.1016\/j.clinbiochem.2013.06.023_bb0045","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/clinchem\/46.5.697","article-title":"Influence of glomerular filtration rate on non-(1\u201384) parathyroid hormone (PTH) detected by intact PTH assays","volume":"46","author":"Brossard","year":"2000","journal-title":"Clin Chem"},{"issue":"4","key":"10.1016\/j.clinbiochem.2013.06.023_bb0050","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1210\/endo.142.4.8093","article-title":"Synthetic carboxyl-terminal fragments of parathyroid hormone (PTH) decrease ionized calcium concentration in rats by acting on a receptor different from the PTH\/PTH-related peptide receptor","volume":"142","author":"Nguyen-Yamamoto","year":"2001","journal-title":"Endocrinology"},{"issue":"9","key":"10.1016\/j.clinbiochem.2013.06.023_bb0055","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1093\/ndt\/gfm268","article-title":"UK consensus conference on early chronic kidney disease \u2014 6 and 7 February 2007","volume":"22","author":"Archibald","year":"2007","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"10.1016\/j.clinbiochem.2013.06.023_bb0060","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1359\/jbmr.071117","article-title":"Effects of growth hormone administration on bone mineral metabolism, PTH sensitivity and PTH secretory rhythm in postmenopausal women with established osteoporosis","volume":"23","author":"Joseph","year":"2008","journal-title":"J Bone Miner Res"},{"issue":"11","key":"10.1016\/j.clinbiochem.2013.06.023_bb0065","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1007\/s00198-009-1142-4","article-title":"Fibroblast growth factor-23 is associated with C-reactive protein, serum phosphate and bone mineral density in chronic kidney disease","volume":"21","author":"Manghat","year":"2010","journal-title":"Osteoporos Int"},{"issue":"11","key":"10.1016\/j.clinbiochem.2013.06.023_bb0070","first-page":"3923","article-title":"Accumulation of a non-(1\u201384) molecular form of parathyroid hormone (PTH) detected by intact PTH assay in renal failure: importance in the interpretation of PTH values","volume":"81","author":"Brossard","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.clinbiochem.2013.06.023_bb0075","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1053\/j.ajkd.2011.12.035","article-title":"Ergocalciferol and cholecalciferol in CKD","volume":"60","author":"Nigwekar","year":"2012","journal-title":"Am J Kidney Dis"},{"issue":"18","key":"10.1016\/j.clinbiochem.2013.06.023_bb0080","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.clinbiochem.2012.08.006","article-title":"Clinical evaluation of two novel biointact PTH(1\u201384) assays in hemodialysis patients","volume":"45","author":"Hecking","year":"2012","journal-title":"Clin Biochem"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.06.023_bb0085","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/ki.2009.374","article-title":"Parathyroid hormone measurement in CKD","volume":"77","author":"Souberbielle","year":"2010","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.06.023_bb0090","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0085-2538(15)47156-X","article-title":"A novel mechanism for skeletal resistance in uremia","volume":"58","author":"Slatopolsky","year":"2000","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.clinbiochem.2013.06.023_bb0095","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1053\/ajkd.2002.34519","article-title":"PTH 1\u201384 and PTH \u201c7\u201384\u201d in the noninvasive diagnosis of renal bone disease","volume":"40","author":"Coen","year":"2002","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"10.1016\/j.clinbiochem.2013.06.023_bb0100","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1046\/j.1523-1755.2001.00949.x","article-title":"Improved assessment of bone turnover by the PTH-(1\u201384)\/large C-PTH fragments ratio in ESRD patients","volume":"60","author":"Monier-Faugere","year":"2001","journal-title":"Kidney Int"},{"issue":"8","key":"10.1016\/j.clinbiochem.2013.06.023_bb0105","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1681\/ASN.2009121208","article-title":"Bone mass and microarchitecture in CKD patients with fracture","volume":"21","author":"Nickolas","year":"2010","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.clinbiochem.2013.06.023_bb0110","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/ndt\/gfr317","article-title":"Diagnostic usefulness of bone mineral density and biochemical markers of bone turnover in predicting fracture in CKD stage 5D patients \u2014 a single-center cohort study","volume":"27","author":"Iimori","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.clinbiochem.2013.06.023_bb0115","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.bone.2008.11.016","article-title":"Serum 25-hydroxyvitamin D as an independent determinant of 1\u201384 PTH and bone mineral density in non-diabetic predialysis CKD patients","volume":"44","author":"Tomida","year":"2009","journal-title":"Bone"},{"key":"10.1016\/j.clinbiochem.2013.06.023_bb0120","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1440-1797.2009.01159.x","article-title":"Review article: bone density in patients with chronic kidney disease stages 4\u20135","volume":"14","author":"OTT","year":"2009","journal-title":"Nephrology"}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912013003007?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912013003007?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:45:12Z","timestamp":1757864712000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912013003007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":24,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0009912013003007"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2013.06.023","relation":{},"ISSN":["0009-9120"],"issn-type":[{"value":"0009-9120","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The relationship between intact PTH and biointact PTH (1\u201384) with bone and mineral metabolism in pre-dialysis chronic kidney disease (CKD)","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2013.06.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}