{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T16:41:28Z","timestamp":1774543288212,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.clinbiochem.2021.04.010","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T22:07:29Z","timestamp":1618524449000},"page":"20-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Mid-regional pro-atrial natriuretic peptide levels before and after hemodialysis predict long-term prognosis"],"prefix":"10.1016","volume":"94","author":[{"given":"Rasmus Bo","family":"Hasselbalch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas Henrik","family":"Kristensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ture Lange","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis Lind","family":"Plesner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7126-8691","authenticated-orcid":false,"given":"Casper","family":"Rydahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten","family":"Schou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens P.","family":"Goetze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Bundgaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasper Karmark","family":"Iversen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10041","key":"10.1016\/j.clinbiochem.2021.04.010_b0005","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0140-6736(16)30508-6","article-title":"The heart and vascular system in dialysis","volume":"388","author":"Wanner","year":"2016","journal-title":"Lancet"},{"issue":"25","key":"10.1016\/j.clinbiochem.2021.04.010_b0010","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1016\/j.jacc.2007.09.021","article-title":"Natriuretic peptides","volume":"50","author":"Daniels","year":"2007","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.clinbiochem.2021.04.010_b0015","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1111\/j.1742-4658.2011.08082.x","article-title":"Natriuretic peptide metabolism, clearance and degradation","volume":"278","author":"Potter","year":"2011","journal-title":"FEBS J."},{"issue":"1","key":"10.1016\/j.clinbiochem.2021.04.010_b0020","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1186\/s12967-019-02165-2","article-title":"Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients","volume":"17","author":"Yagmur","year":"2019","journal-title":"J. Transl. Med."},{"issue":"13","key":"10.1016\/j.clinbiochem.2021.04.010_b0025","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.2217\/bmm-2019-0158","article-title":"ProANP and proBNP in plasma as biomarkers of heart failure","volume":"13","author":"Davidovski","year":"2019","journal-title":"Biomarkers Med."},{"issue":"1","key":"10.1016\/j.clinbiochem.2021.04.010_b0030","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1373\/clinchem.2003.021204","article-title":"Immunoluminometric assay for the midregion of pro-atrial natriuretic peptide in human plasma","volume":"50","author":"Morgenthaler","year":"2004","journal-title":"Clin. Chem."},{"issue":"6","key":"10.1016\/j.clinbiochem.2021.04.010_b0035","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1177\/2047487314538856","article-title":"MR-proANP improves prediction of mortality and cardiovascular events in patients with STEMI","volume":"22","author":"Lindberg","year":"2015","journal-title":"Eur. J. Preventive Cardiol."},{"issue":"3","key":"10.1016\/j.clinbiochem.2021.04.010_b0040","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/dom.13583","article-title":"Prevalence of heart failure and the diagnostic value of MR-proANP in outpatients with type 2 diabetes","volume":"21","author":"Jensen","year":"2019","journal-title":"Diabetes Obes. Metab."},{"issue":"6","key":"10.1016\/j.clinbiochem.2021.04.010_b0045","doi-asserted-by":"crossref","first-page":"e455","DOI":"10.1212\/WNL.0000000000004922","article-title":"Midregional proatrial natriuretic peptide improves risk stratification after ischemic stroke","volume":"90","author":"De Marchis","year":"2018","journal-title":"Neurology"},{"issue":"9","key":"10.1016\/j.clinbiochem.2021.04.010_b0050","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1515\/cclm-2016-0760","article-title":"The natriuretic peptide MR-proANP predicts all-cause mortality and adverse outcome in community patients: a 10-year follow-up study","volume":"55","author":"Odermatt","year":"2017","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.clinbiochem.2021.04.010_b0055","doi-asserted-by":"crossref","unstructured":"F.S. Gaborit, C. Kistorp, T. Kumler, C. Hassager, N. Tonder, K. Iversen, P.M. Hansen, P.R. Kamstrup, J. Faber, L. Kober, M. Schou, Diagnostic utility of MR-proANP and NT-proBNP in elderly outpatients with a high risk of heart failure: the Copenhagen heart failure risk study, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2020) 1-12.","DOI":"10.1080\/1354750X.2020.1732466"},{"issue":"19","key":"10.1016\/j.clinbiochem.2021.04.010_b0060","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1016\/j.jacc.2010.02.025","article-title":"Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea","volume":"55","author":"Maisel","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"issue":"3","key":"10.1016\/j.clinbiochem.2021.04.010_b0065","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1159\/000064100","article-title":"Increased circulating levels of natriuretic peptides predict future cardiac event in patients with chronic hemodialysis","volume":"92","author":"Goto","year":"2002","journal-title":"Nephron"},{"issue":"6","key":"10.1016\/j.clinbiochem.2021.04.010_b0070","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1159\/000073442","article-title":"The prognostic role of atrial natriuretic peptides in hemodialysis patients","volume":"21","author":"Nakatani","year":"2003","journal-title":"Blood Purif."},{"key":"10.1016\/j.clinbiochem.2021.04.010_b0075","doi-asserted-by":"crossref","unstructured":"I. Odar-Cederlof, F. Ericsson, E. Theodorsson, C.M. Kjellstrand, Neuropeptide-Y and atrial natriuretic peptide as prognostic markers in patients on hemodialysis, ASAIO journal (American Society for Artificial Internal Organs : 1992) 49(1) (2003) 74-80.","DOI":"10.1097\/00002480-200301000-00012"},{"issue":"5","key":"10.1016\/j.clinbiochem.2021.04.010_b0080","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1177\/089686080602600515","article-title":"B-type natriuretic peptide and amino-terminal atrial natriuretic peptide predict survival in peritoneal dialysis","volume":"26","author":"Rutten","year":"2006","journal-title":"Peritoneal Dialysis Int."},{"key":"10.1016\/j.clinbiochem.2021.04.010_b0085","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s12882-015-0212-4","article-title":"The role of natriuretic peptides in volume assessment and mortality prediction in Haemodialysis patients","volume":"16","author":"Sivalingam","year":"2015","journal-title":"BMC Nephrol."},{"issue":"3","key":"10.1016\/j.clinbiochem.2021.04.010_b0090","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1111\/j.1523-1755.2005.00534.x","article-title":"Adrenomedullin reflects cardiac dysfunction, excessive blood volume, and inflammation in hemodialysis patients","volume":"68","author":"Yoshihara","year":"2005","journal-title":"Kidney Int."},{"issue":"7","key":"10.1016\/j.clinbiochem.2021.04.010_b0095","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1681\/ASN.V1271508","article-title":"Cardiac natriuretic peptides are related to left ventricular mass and function and predict mortality in dialysis patients","volume":"12","author":"Zoccali","year":"2001","journal-title":"J. Am. Society Nephrol.: JASN"},{"issue":"1","key":"10.1016\/j.clinbiochem.2021.04.010_b0100","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000343406","article-title":"Comparison of the diagnostic performance of three natriuretic peptides in hemodialysis patients: which is the appropriate biomarker?","volume":"36","author":"Artunc","year":"2012","journal-title":"Kidney Blood Pressure Res."},{"issue":"3","key":"10.1016\/j.clinbiochem.2021.04.010_b0105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017803","article-title":"The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort","volume":"6","author":"Gouya","year":"2011","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.clinbiochem.2021.04.010_b0110","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1007\/s10554-019-01619-4","article-title":"Changes in left ventricular filling parameters before and after dialysis in patients with end stage renal disease","volume":"35","author":"Ersboll","year":"2019","journal-title":"Int. J. Cardiovasc. Imaging"},{"issue":"3","key":"10.1016\/j.clinbiochem.2021.04.010_b0115","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.nefro.2018.10.007","article-title":"FGF23 in hemodialysis patients is associated with left ventricular hypertrophy and reduced ejection fraction","volume":"39","author":"Nielsen","year":"2019","journal-title":"Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia"},{"issue":"4","key":"10.1016\/j.clinbiochem.2021.04.010_b0120","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1080\/1354750X.2018.1428359","article-title":"YKL-40 in patients with end-stage renal disease receiving haemodialysis","volume":"23","author":"Nielsen","year":"2018","journal-title":"Biomarkers"},{"issue":"1","key":"10.1016\/j.clinbiochem.2021.04.010_b0125","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/hdi.12342","article-title":"Chronic obstructive pulmonary disease in patients with end-stage kidney disease on hemodialysis, Hemodialysis international","volume":"20","author":"Plesner","year":"2016","journal-title":"Int. Symp. Home Hemodialysis"},{"key":"10.1016\/j.clinbiochem.2021.04.010_b0130","unstructured":"P. Ponikowski, A.A. Voors, S.D. Anker, H. Bueno, J.G.F. Cleland, A.J.S. Coats, V. Falk, J.R. Gonz\u00e1lez-Juanatey, V.-P. Harjola, E.A. Jankowska, M. Jessup, C. Linde, P. Nihoyannopoulos, J.T. Parissis, B. Pieske, J.P. Riley, G.M.C. Rosano, L.M. Ruilope, F. Ruschitzka, F.H. Rutten, P. van der Meer, G. Filippatos, J.J.V. McMurray, V. Aboyans, S. Achenbach, S. Agewall, N. Al-Attar, J.J. Atherton, J. Bauersachs, A. John Camm, S. Carerj, C. Ceconi, A. Coca, P. Elliott, \u00c7. Erol, J. Ezekowitz, C. Fern\u00e1ndez-Golf\u00edn, D. Fitzsimons, M. Guazzi, M. Guenoun, G. Hasenfuss, G. Hindricks, A.W. Hoes, B. Iung, T. Jaarsma, P. Kirchhof, J. Knuuti, P. Kolh, S. Konstantinides, M. Lainscak, P. Lancellotti, G.Y.H. Lip, F. Maisano, C. Mueller, M.C. Petrie, M.F. Piepoli, S.G. Priori, A. Torbicki, H. Tsutsui, D.J. van Veldhuisen, S. Windecker, C. Yancy, J.L. Zamorano, J.L. Zamorano, V. Aboyans, S. Achenbach, S. Agewall, L. Badimon, G. Bar\u00f3n-Esquivias, H. Baumgartner, J.J. Bax, H. Bueno, S. Carerj, V. Dean, \u00c7. Erol, D. Fitzsimons, O. Gaemperli, P. Kirchhof, P. Kolh, P. Lancellotti, G.Y.H. Lip, P. Nihoyannopoulos, M.F. Piepoli, P. Ponikowski, M. Roffi, A. Torbicki, A. Vaz Carneiro, S. Windecker, H.S. Sisakian, E. Isayev, A. Kurlianskaya, W. Mullens, M. Tokmakova, P. Agathangelou, V. Melenovsky, H. Wiggers, M. Hassanein, T. Uuetoa, J. Lommi, E.S. Kostovska, Y. Juilli\u00e8re, A. Aladashvili, A. Luchner, C. Chrysohoou, N. Nyolczas, G. Thorgeirsson, J. Marc Weinstein, A. Di Lenarda, N. Aidargaliyeva, G. Bajraktari, M. Beishenkulov, G. Kamzola, T. Abdel-Massih, J. \u010celutkien\u0117, S. Noppe, A. Cassar, E. Vataman, S. Abir-Khalil, P. van Pol, R. Mo, E. Straburzy\u0144ska-Migaj, C. Fonseca, O. Chioncel, E. Shlyakhto, P. Otasevic, E. Goncalvesov\u00e1, M. Lainscak, B. D\u00edaz Molina, M. Schaufelberger, T. Suter, M.B. Y\u0131lmaz, L. Voronkov, C. Davies, 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failureThe Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC, European heart journal 37(27) (2016) 2129-2200."},{"issue":"30","key":"10.1016\/j.clinbiochem.2021.04.010_b0135","doi-asserted-by":"crossref","first-page":"5381","DOI":"10.1002\/sim.5958","article-title":"Estimating and comparing time-dependent areas under receiver operating characteristic curves for censored event times with competing risks","volume":"32","author":"Blanche","year":"2013","journal-title":"Stat. Med."},{"key":"10.1016\/j.clinbiochem.2021.04.010_b0140","unstructured":"R.C. Team, R: A Language and Eviroment for Statistical Computing, 2016."},{"key":"10.1016\/j.clinbiochem.2021.04.010_b0145","unstructured":"H.W.a.M.A.a.J.B.a.W.C.a.L.D.A.M.a.R.F.a.G.G.a.A.H.a.L.H.a.J.H. and Max Kuhn and Thomas Lin Pedersen and Evan Miller and Stephan Milton Bache and Kirill M\u00fcller and Jeroen Ooms and David Robinson and Dana Paige Seidel and Vitalie Spinu and Kohske Takahashi and Davis Vaughan and Claus Wilke and Kara Woo and Hiroaki Yutani, Welcome to the tidyverse, Journal of Open Source Software (2019)."},{"issue":"16\u201317","key":"10.1016\/j.clinbiochem.2021.04.010_b0150","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.clinbiochem.2015.07.031","article-title":"Plasma concentrations of novel cardiac biomarkers before and after hemodialysis session","volume":"48","author":"Mueller","year":"2015","journal-title":"Clin. Biochem."},{"issue":"20","key":"10.1016\/j.clinbiochem.2021.04.010_b0155","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1016\/j.jacc.2007.08.012","article-title":"Comparison of midregional pro-atrial natriuretic peptide with N-terminal pro-B-type natriuretic peptide in predicting survival in patients with chronic heart failure","volume":"50","author":"von Haehling","year":"2007","journal-title":"J. Am. Coll. Cardiol."},{"issue":"2","key":"10.1016\/j.clinbiochem.2021.04.010_b0160","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/ki.1992.46","article-title":"Immunocytochemical localization of proANF 1\u201330, proANF 31\u201367 and atrial natriuretic factor in the kidney","volume":"41","author":"Ramirez","year":"1992","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.clinbiochem.2021.04.010_b0165","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/ki.1997.152","article-title":"Increased atrial natriuretic peptide mRNA expression in the kidney of diabetic rats","volume":"51","author":"Shin","year":"1997","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.clinbiochem.2021.04.010_b0170","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1046\/j.1523-1755.1998.00163.x","article-title":"Increased renal ANP synthesis, but decreased or unchanged cardiac ANP synthesis in water-deprived and salt-restricted rats","volume":"54","author":"Shin","year":"1998","journal-title":"Kidney Int."},{"issue":"7","key":"10.1016\/j.clinbiochem.2021.04.010_b0175","doi-asserted-by":"crossref","first-page":"513","DOI":"10.5301\/ijao.5000333","article-title":"The effect of hemodialysis on cardiac enzyme levels and echocardiographic parameters","volume":"37","author":"Ingec","year":"2014","journal-title":"Int. J. Artificial Organs"},{"issue":"6","key":"10.1016\/j.clinbiochem.2021.04.010_b0180","doi-asserted-by":"crossref","first-page":"392","DOI":"10.5414\/CNP68392","article-title":"Cardiac biomarkers are influenced by dialysis characteristics","volume":"68","author":"Sommerer","year":"2007","journal-title":"Clin. Nephrol."}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912021001132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009912021001132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:58:11Z","timestamp":1757865491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009912021001132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":36,"alternative-id":["S0009912021001132"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2021.04.010","relation":{},"ISSN":["0009-9120"],"issn-type":[{"value":"0009-9120","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mid-regional pro-atrial natriuretic peptide levels before and after hemodialysis predict long-term prognosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2021.04.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}