{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T08:08:59Z","timestamp":1778400539121,"version":"3.51.4"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Biochemistry"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.clinbiochem.2026.111127","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T15:55:15Z","timestamp":1776873315000},"page":"111127","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Troponin I interference in an 18-year-old patient with bradycardia: a case study"],"prefix":"10.1016","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1110-5666","authenticated-orcid":false,"given":"Huifeng","family":"Qian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyong","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunchang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinbiochem.2026.111127_b0005","article-title":"High-sensitivity point-of-care measurement of cardiac troponin","author":"Cullen","year":"2025","journal-title":"Eur. Heart J."},{"issue":"12","key":"10.1016\/j.clinbiochem.2026.111127_b0010","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.3390\/jcm14124241","article-title":"The pathophysiology of cardiac troponin release and the various circulating cardiac troponin forms-potential clinical implications","volume":"14","author":"Mair","year":"2025","journal-title":"J. Clin. Med."},{"issue":"1","key":"10.1016\/j.clinbiochem.2026.111127_b0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e23788","article-title":"Investigating outlier rates of cardiac troponin I and troponin T assays: a systematic review","volume":"10","author":"Zhang","year":"2024","journal-title":"Heliyon"},{"issue":"24","key":"10.1016\/j.clinbiochem.2026.111127_b0020","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1161\/CIRCULATIONAHA.125.076296","article-title":"Troponin autoantibodies, macrotroponin, and assay interference","volume":"152","author":"Wittfooth","year":"2025","journal-title":"Circulation"},{"issue":"15","key":"10.1016\/j.clinbiochem.2026.111127_b0025","doi-asserted-by":"crossref","first-page":"307","DOI":"10.21037\/atm.2017.07.40","article-title":"Anti-cardiac troponin antibodies in clinical human disease: a systematic review","volume":"5","author":"Vilela","year":"2017","journal-title":"Ann. Transl. Med."},{"issue":"15","key":"10.1016\/j.clinbiochem.2026.111127_b0030","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1161\/CIRCULATIONAHA.123.066565","article-title":"Half-life and clearance of cardiac troponin I and troponin T in humans","volume":"150","author":"Kristensen","year":"2024","journal-title":"Circulation"},{"issue":"14","key":"10.1016\/j.clinbiochem.2026.111127_b0035","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.jacc.2025.02.016","article-title":"Cardiac troponins and cardiovascular disease risk prediction: an individual-participant-data meta-analysis","volume":"85","author":"Shah","year":"2025","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.clinbiochem.2026.111127_b0040","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3343\/alm.2022.42.1.3","article-title":"Hormone immunoassay interference: a 2021 update","volume":"42","author":"Ghazal","year":"2022","journal-title":"Ann. Lab. Med."},{"issue":"6","key":"10.1016\/j.clinbiochem.2026.111127_b0045","doi-asserted-by":"crossref","DOI":"10.1002\/mbo3.70098","article-title":"Resolving heterophile antibody interference in viral serology using blocking tubes","volume":"14","author":"Song","year":"2025","journal-title":"MicrobiologyOpen"},{"issue":"22","key":"10.1016\/j.clinbiochem.2026.111127_b0050","doi-asserted-by":"crossref","first-page":"11937","DOI":"10.3390\/ijms252211937","article-title":"Troponin test, not only a number: an unusual case of false positive","volume":"25","author":"Salvatici","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.clinbiochem.2026.111127_b0055","doi-asserted-by":"crossref","first-page":"e134","DOI":"10.1016\/j.hlc.2025.03.006","article-title":"Macrotroponin: a case series and review of the literature","volume":"34","author":"Makarious","year":"2025","journal-title":"Heart Lung Circ."},{"issue":"8","key":"10.1016\/j.clinbiochem.2026.111127_b0060","first-page":"e955","article-title":"Macrotroponin causing elevation in cardiac troponin I","volume":"30","author":"Wong","year":"2014","journal-title":"Can. J. Cardiol."},{"issue":"7","key":"10.1016\/j.clinbiochem.2026.111127_b0065","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.pathol.2021.04.005","article-title":"Effect of macrotroponin on the utility of cardiac troponin I as a prognostic biomarker for long term total and cardiovascular disease mortality","volume":"53","author":"Lam","year":"2021","journal-title":"Pathology"},{"issue":"12","key":"10.1016\/j.clinbiochem.2026.111127_b0070","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.123.035128","article-title":"Role of antitroponin antibodies and macrotroponin in the clinical interpretation of cardiac troponin","volume":"13","author":"Salaun","year":"2024","journal-title":"J. Am. Heart Assoc."},{"issue":"1","key":"10.1016\/j.clinbiochem.2026.111127_b0075","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1186\/s12879-025-10642-x","article-title":"A rare case of macroamylasemia in a patient with SARS-CoV-2 infection","volume":"25","author":"Aponso","year":"2025","journal-title":"BMC Infect. Dis."},{"issue":"9","key":"10.1016\/j.clinbiochem.2026.111127_b0080","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1093\/clinchem\/hvaf077","article-title":"Exploring the role of cardiac troponin-specific autoantibodies: prolonged cardiac troponin elimination, reduced clearance, and variable interference across 5 commercial assays","volume":"71","author":"Salonen","year":"2025","journal-title":"Clin. Chem."},{"issue":"1","key":"10.1016\/j.clinbiochem.2026.111127_b0085","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1373\/clinchem.2016.261602","article-title":"Anti-cardiac troponin autoantibodies are specific to the conformational epitopes formed by cardiac troponin I and troponin T in the ternary troponin complex","volume":"63","author":"Vylegzhanina","year":"2017","journal-title":"Clin. Chem."}],"container-title":["Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000991202600055X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000991202600055X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T07:49:12Z","timestamp":1778399352000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000991202600055X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":17,"alternative-id":["S000991202600055X"],"URL":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2026.111127","relation":{},"ISSN":["0009-9120"],"issn-type":[{"value":"0009-9120","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Troponin I interference in an 18-year-old patient with bradycardia: a case study","name":"articletitle","label":"Article Title"},{"value":"Clinical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinbiochem.2026.111127","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111127"}}