{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T19:02:20Z","timestamp":1785265340129,"version":"3.55.0"},"reference-count":98,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["patient-research.elsevier.com","cidjournal.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Dermatology"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.clindermatol.2014.04.011","type":"journal-article","created":{"date-parts":[[2014,8,23]],"date-time":"2014-08-23T10:22:00Z","timestamp":1408789320000},"page":"633-645","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["The role of neuropeptides in the control of regional immunity"],"prefix":"10.1016","volume":"32","author":[{"given":"Torello","family":"Lotti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo Massimiliano","family":"D\u2019Erme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Hercogov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clindermatol.2014.04.011_bb0005","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1046\/j.1365-4362.1999.00767.x","article-title":"Neuropeptides and skin disorders. The new frontiers of neuro-endocrine-cutaneous immunology","volume":"38","author":"Lotti","year":"1999","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1046\/j.1529-8019.2003.01621.x","article-title":"The neuro-immuno-cutaneous-endocrine network: Relationship between mind and skin","volume":"16","author":"Brazzini","year":"2003","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0015","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1365-4632.2002.01408.x","article-title":"Can the brain inhibit inflammation generated in the skin? The lesson of gamma-melanocyte-stimulating hormone","volume":"41","author":"Lotti","year":"2002","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0020","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1468-3083.1998.tb00736.x","article-title":"Neuropeptides: Role in inflammatory skin diseases","volume":"10","author":"Luger","year":"1998","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0025","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.det.2005.05.021","article-title":"Psychosomatic factors in dermatology","volume":"23","author":"Urpe","year":"2005","journal-title":"Dermatol Clin"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0030","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.det.2005.05.017","article-title":"Stress and psychoneuroimmunologic factors in dermatology","volume":"23","author":"Urpe","year":"2005","journal-title":"Dermatol Clin"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0035","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1600-0625.1998.tb00307.x","article-title":"Neuropeptides in the skin: Interactions between the neuroendocrine and the skin immune systems","volume":"7","author":"Scholzen","year":"1998","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0040","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0031-6997(25)06664-5","article-title":"Capsaicin: Cellular targets, mechanism of action, and selectivity for thin sensory neurons","volume":"43","author":"Holzer","year":"1991","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0045","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/39807","article-title":"The capsaicin receptor: A heat-activated ion channel in the pain pathway","volume":"389","author":"Caterina","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0050","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0306-3623(94)90049-3","article-title":"The vanilloid (capsaicin) receptor: Receptor types and species differences","volume":"25","author":"Szallasi","year":"1994","journal-title":"Gen Pharmacol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0055","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/0190-9622(95)91395-5","article-title":"Neuropeptides in skin","volume":"33","author":"Lotti","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0060","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1152\/physrev.00026.2005","article-title":"Neuronal control of skin function: The skin as a neuroimmunoendocrine organ","volume":"86","author":"Roosterman","year":"2006","journal-title":"Physiol Rev"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0065","first-page":"83","article-title":"Dermatological and immunological conditions due to nerve lesions","volume":"28","author":"Bove","year":"2013","journal-title":"Funct Neurol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0070","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0738-081X(99)00083-8","article-title":"Neuropeptides and endothelial injury in cutaneous vasculitis","volume":"17","author":"Bianchi","year":"1999","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0075","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/aja.1001910404","article-title":"Animmunocytochemical study of cutaneous innervation and the distribution of neuropeptides and protein gene products 9.5 in man and commonly employed laboratory animals","volume":"191","author":"Karanth","year":"1991","journal-title":"J Anat"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0080","first-page":"121","article-title":"Neuropeptidi e cute","volume":"124","author":"Girolomoni","year":"1989","journal-title":"G Ital Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0085","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1067\/mjd.2002.118362","article-title":"Isotopic response after herpesvirus infection: An update","volume":"46","author":"Ruocco","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0090","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1365-4362.1992.tb03938.x","article-title":"Substance P provokes cutaneous erythema and edema through a histamine-independent pathway","volume":"31","author":"Cappugi","year":"1992","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0095","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.1073\/pnas.88.8.3200","article-title":"Cytokine regulation of substance P expression in sympathetic neurons","volume":"88","author":"Freidin","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0100","first-page":"105","article-title":"Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS","volume":"4","author":"Bost","year":"1992","journal-title":"Reg Immunol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0105","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1749-6632.1999.tb08684.x","article-title":"The role of proopiomelanocortin-derived peptides in skin fibroblast and mast cell functions","volume":"885","author":"Teofoli","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0110","first-page":"403908","article-title":"Psychological stress and the cutaneous immune response: Roles of the HPA axis and the sympathetic nervous system in atopic dermatitis and psoriasis","author":"Hall","year":"2012","journal-title":"Dermatol Res Pract"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0115","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1001\/archderm.137.1.53","article-title":"Psychological stress perturbs epidermal permeability barrier homeostasis: Implications for the pathogenesis of stress-associated skin disorders","volume":"137","author":"Garg","year":"2001","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0120","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.0022-202X.2005.23589.x","article-title":"Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity","volume":"124","author":"Choi","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0125","doi-asserted-by":"crossref","first-page":"R1657","DOI":"10.1152\/ajpregu.00010.2006","article-title":"Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function","volume":"291","author":"Choi","year":"2006","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0130","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1172\/JCI31726","article-title":"Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice","volume":"117","author":"Aberg","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0135","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/jid.2011.334","article-title":"Substance P (SP) induces expression of functional corticotropin-releasing hormone receptor-1 (CRHR-1) in human mast cells","volume":"132","author":"Asadi","year":"2012","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0140","doi-asserted-by":"crossref","first-page":"7665","DOI":"10.4049\/jimmunol.174.12.7665","article-title":"Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor","volume":"174","author":"Cao","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0145","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1006\/brbi.1998.0541","article-title":"Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P: A link to neurogenic skin disorders","volume":"13","author":"Singh","year":"1999","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0150","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/sj.jid.5701079","article-title":"Further exploring the brain-skin connection: Stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice","volume":"128","author":"Pavlovic","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0155","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1177\/120347549800300205","article-title":"Modification of LC phenotype and suppression of contact hypersensitivity response by stress","volume":"3","author":"Hosoi","year":"1998","journal-title":"J Cutan Med Surg"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0160","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1038\/sj.jid.5701144","article-title":"The effects of acute social stress on epidermal Langerhans' cell frequency and expression of cutaneous neuropeptides","volume":"128","author":"Kleyn","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0165","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s004030050194","article-title":"Binding and in vitro modulation of human epidermal Langerhans cell functions by substance P","volume":"289","author":"Staniek","year":"1997","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0170","doi-asserted-by":"crossref","first-page":"6020","DOI":"10.4049\/jimmunol.181.9.6020","article-title":"Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity","volume":"181","author":"Ding","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0175","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S1470-2045(04)01597-9","article-title":"Stress, depression, the immune system, and cancer","volume":"5","author":"Reiche","year":"2004","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0180","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1111\/j.1468-3083.2011.04268.x","article-title":"The importance of stressful family events in psoriatic patients: A retrospective study","volume":"26","author":"Campolmi","year":"2012","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0185","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1046\/j.1365-2230.2001.00834.x","article-title":"Psychological influences in psoriasis","volume":"26","author":"Griffiths","year":"2001","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0190","article-title":"Therapeutic implications of adding the psychotropic drug escitalopram in the treatment of patients suffering from moderate-severe psoriasis and psychiatric comorbidity: A retrospective study","author":"D'Erme","year":"2012","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0195","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1751-1097.1998.tb02490.x","article-title":"A role for neuropeptides in UVB-induced systemic immunosuppression","volume":"68","author":"Garssen","year":"1998","journal-title":"Photochem Photobiol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0200","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/000155598433368","article-title":"Psoriatic keratinocytes express high levels of nerve growth factor","volume":"78","author":"Raychaudhuri","year":"1998","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0205","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1046\/j.1365-2133.2000.03617.x","article-title":"Nerve growth factor and its receptor system in psoriasis","volume":"143","author":"Raychaudhuri","year":"2000","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0210","first-page":"60","article-title":"Psoriasis and the nervous system","volume":"186","author":"Pincelli","year":"1994","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0215","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1365-2230.1995.tb01354.x","article-title":"Neuropeptides and general neuronal marker in psoriasis\u2013an immunohistochemical study","volume":"20","author":"Al'Abadie","year":"1995","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0220","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s004030050249","article-title":"Intraepidermal nerve fiber expression of calcitonin gene-related peptide, vasoactive intestinal peptide and substance P in psoriasis","volume":"289","author":"Chan","year":"1997","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0225","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/1523-1747.ep12499846","article-title":"Substance P is diminished and vasoactive intestinal peptide is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes","volume":"98","author":"Pincelli","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0230","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1046\/j.1365-4362.1998.00533.x","article-title":"Double-labeled immunofluorescence study of cutaneous nerves in psoriasis","volume":"37","author":"Jiang","year":"1998","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0235","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1046\/j.1365-2133.1998.02500.x","article-title":"Expression of nerve growth factor receptors in cutaneous inflammation","volume":"139","author":"Bull","year":"1998","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0240","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1365-4362.1993.tb01442.x","article-title":"Psychoneuroimmunology and dermatology","volume":"32","author":"Farber","year":"1993","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0245","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1056\/NEJMra074081","article-title":"Atopic dermatitis","volume":"358","author":"Bieber","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0250","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1038\/jid.2013.50","article-title":"Recapitulating atopic dermatitis in three dimensions: Cross talk between keratinocytes and nerve fibers","volume":"133","author":"Pincelli","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0255","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4103\/0019-5154.62735","article-title":"Nerve growth factor, neuropeptides and cutaneous nerves in atopic dermatitis","volume":"55","author":"Hodeib","year":"2010","journal-title":"Indian J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0260","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2340\/00015555-1188","article-title":"Psychoneuroimmunology of psychological stress and atopic dermatitis: Pathophysiologic and therapeutic updates","volume":"92","author":"Su\u00e1rez","year":"2012","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0265","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s004280050179","article-title":"Cutaneous nerves in atopic dermatitis. A histological, immunohistochemical and electron microscopic study","volume":"432","author":"Urashima","year":"1998","journal-title":"Virchows Arch"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0270","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/01.all.0000183111.78558.4d","article-title":"Neuroimmunological findings in allergic skin diseases","volume":"5","author":"Raap","year":"2005","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0275","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0091-6749(92)90134-N","article-title":"Increased number of immunoreactive nerve fibers in atopic dermatitis","volume":"90","author":"Tobin","year":"1992","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0280","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1365-2133.2002.04803.x","article-title":"Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis","volume":"147","author":"Toyoda","year":"2002","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0285","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s00403-002-0378-z","article-title":"Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema","volume":"295","author":"J\u03b4rvikallio","year":"2003","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0290","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1038\/jid.2012.464","article-title":"Epidermal nerve fibers modulate keratinocyte growth via neuropeptide signaling in an innervated skin model","volume":"133","author":"Roggenkamp","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0295","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1365-2133.2012.11197.x","article-title":"Guidelines for the management of vitiligo: The European Dermatology Forum consensus","volume":"168","author":"Taieb","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0300","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1111\/dth.12010","article-title":"Classification of vitiligo: A challenging endeavor","volume":"25","author":"Hercogov\u00e1","year":"2012","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0305","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1046\/j.1468-3083.2003.00792_6.x","article-title":"Substance P may play a part during depigmentation in vitiligo. A pilot study","volume":"17","author":"Falabella","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0310","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1001\/archderm.1966.01600270019004","article-title":"Vitiligo and sympathectomy. The effect of sympathectomy and alphamelanocyte stimulating hormone","volume":"94","author":"Lerner","year":"1966","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0315","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jdermsci.2010.08.004","article-title":"Analysis of the expression profile of CRH-POMC system genes in vitiligo skin biopsies","volume":"60","author":"Reimann","year":"2010","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0320","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1365-2133.1994.tb08486.x","article-title":"Neuropeptide and neuronal marker studies in vitiligo","volume":"131","author":"Al\u2019Abadie","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0325","first-page":"53","article-title":"Markers for vitiligo related neuropeptides in human skin nerve fibers","volume":"54","author":"Hristakieva","year":"2000","journal-title":"Acta Med Croatica"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0330","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1177\/120347541201600404","article-title":"Potential role of neurogenic inflammatory factors in the pathogenesis of vitiligo","volume":"16","author":"Yu","year":"2012","journal-title":"J Cutan Med Surg"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0335","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jdermsci.2007.06.004","article-title":"Gene expression analysis of melanocortin system in vitiligo","volume":"48","author":"Kingo","year":"2007","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0340","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-4362.1995.tb03616.x","article-title":"Isotopic response","volume":"34","author":"Wolf","year":"1995","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0345","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1111\/j.1525-1470.2012.01776.x","article-title":"Cutaneous lupus after herpes zoster: Isomorphic, isotopic, or both?","volume":"30","author":"Lee","year":"2013","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0350","doi-asserted-by":"crossref","first-page":"242","DOI":"10.5021\/ad.2011.23.2.242","article-title":"Morphea developing at the site of healed herpes zoster","volume":"23","author":"Noh","year":"2011","journal-title":"Ann Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0355","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2340\/00015555-1290","article-title":"Isotopic response of graft versus host disease following herpes zoster infection: Case report and review of the literature","volume":"92","author":"Mehra","year":"2012","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0360","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1097\/DAD.0b013e3182a67d74","article-title":"Monolesional Kaposi sarcoma at the site of slow healing herpes zoster in an HIV + patient: Immunocompromised district in an immunocompromised patient","volume":"35","author":"Ruocco","year":"2013","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0365","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.clindermatol.2011.03.003","article-title":"Opportunistic localization of skin lesions on vulnerable areas","volume":"29","author":"Ruocco","year":"2011","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0370","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1046\/j.1468-3083.2003.00586.x","article-title":"Isomorphic versus isotopic response: Data and hypotheses","volume":"17","author":"Wolf","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0375","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2340\/00015555-0841","article-title":"Synchronous angiosarcoma, melanoma and morphea of the breast skin 14years after radiotherapy for mammary carcinoma","volume":"90","author":"de Giorgi","year":"2010","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0380","first-page":"673","article-title":"Coexistence of malignancy (skin cancer) and immune disorder (discoid lupus erythematosus) on a burn scar: A concrete example of \u201cimmunocompromised district\u201d","volume":"164","author":"Baroni","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0385","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1111\/j.1440-0960.2011.00786.x","article-title":"Discoid lupus erythematosus at a site of previous injury","volume":"54","author":"Ruocco","year":"2013","journal-title":"Australas J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0390","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1111\/j.1529-8019.2010.01300.x","article-title":"Discoid chronic lupus erythematosus at the site of a previously healed cutaneous leishmaniasis: An example of isotopic response","volume":"23","author":"Bardazzi","year":"2010","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0400","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1192\/bjp.162.5.651","article-title":"Impaired in vivo responses in patients with melancholia","volume":"162","author":"Hickie","year":"1993","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0405","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/00006842-199401000-00005","article-title":"Depression modulates pruritus perception: A study of pruritus in psoriasis, atopic dermatitis, and chronic idiopathic urticaria","volume":"56","author":"Gupta","year":"1994","journal-title":"Psychosom Med"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0410","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1001\/jama.1994.03520010059033","article-title":"Effect of hypnotic suggestion on the delayed-type hypersensitivity response","volume":"272","author":"Locke","year":"1994","journal-title":"JAMA"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0415","doi-asserted-by":"crossref","first-page":"563","DOI":"10.2340\/00015555-1400","article-title":"European guideline on chronic pruritus","volume":"92","author":"Weisshaar","year":"2012","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0420","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0196-9781(91)90135-C","article-title":"Central administration of the peptide a MSH inhibits inflammation in the skin","volume":"12","author":"Lipton","year":"1991","journal-title":"Peptides"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0425","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1523\/JNEUROSCI.14-04-02377.1994","article-title":"Antiinflammatory influence of a MSH molecules: Central neurogenic and peripheral actions","volume":"14","author":"Macaluso","year":"1994","journal-title":"J Neurosci"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0430","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1159\/000126650","article-title":"Central neurogenic antiinflammatory action of a MSH. Modulation of peripheral inflammation induced by cytokines and other mediators of inflammation","volume":"59","author":"Ceriani","year":"1994","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0435","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S0190-9622(97)70122-1","article-title":"Single patch of hair at a denervated site in a patient with alopecia universalis","volume":"37","author":"Atkin","year":"1997","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0440","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1111\/j.1346-8138.1994.tb03325.x","article-title":"Healing of chronic atopic dermatitis lesions in skin areas of paraplegia after trauma","volume":"21","author":"Amon","year":"1999","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0445","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1001\/archdermatol.2011.3199","article-title":"Recurrent blistering of the fingertips as a sign of carpal tunnel syndrome: An effect of nerve compression","volume":"148","author":"Baroni","year":"2012","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0450","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/j.1346-8138.2012.01647.x","article-title":"Unilateral bullous pemphigoid in hemiplegic patients: An instance of immunocompromised district","volume":"40","author":"Piccolo","year":"2013","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0455","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0190-9622(94)70022-2","article-title":"Treatment of aquagenic pruritus with topical capsaicin cream","volume":"30","author":"Lotti","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0460","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1056\/NEJM198908173210714","article-title":"Treatment of painful diabetic neuropathy with topical capsaicin","volume":"321","author":"Ross","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0465","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1365-4362.1994.tb04956.x","article-title":"Treatment of cold urticaria","volume":"33","author":"Husz","year":"1994","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0470","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1468-3083.2010.03794.x","article-title":"Serum measurement of interleukin-31 (IL-31) in paediatric atopic dermatitis: Elevated levels correlate with severity scoring","volume":"25","author":"Ezzat","year":"2011","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0475","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1399-3038.2011.01241.x","article-title":"IL-31 significantly correlates with disease activity and Th2 cytokine levels in children with atopic dermatitis","volume":"23","author":"Raap","year":"2012","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0480","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1111\/j.1365-2133.2012.11047.x","article-title":"Mechanistic correlations between two itch biomarkers, cytokine interleukin-31 and neuropeptide \u03b2-endorphin, via STAT3\/calcium axis in atopic dermatitis","volume":"167","author":"Lee","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0485","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1684\/ejd.2011.1470","article-title":"Effects of cyclosporine on pruritus and serum IL-31 levels in patients with atopic dermatitis","volume":"21","author":"Otsuka","year":"2011","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.clindermatol.2014.04.011_bb0490","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.jaci.2011.10.042","article-title":"IL-31 regulates differentiation and filaggrin expression in human organotypic skin models","volume":"129","author":"Cornelissen","year":"2012","journal-title":"J Allergy Clin Immunol"},{"issue":"13","key":"10.1016\/j.clindermatol.2014.04.011_bb0495","first-page":"70512","article-title":"Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation","author":"Choi","year":"2013","journal-title":"Lancet Oncol"}],"container-title":["Clinics in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0738081X14001023?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0738081X14001023?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T09:48:27Z","timestamp":1746352107000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0738081X14001023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":98,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0738081X14001023"],"URL":"https:\/\/doi.org\/10.1016\/j.clindermatol.2014.04.011","relation":{},"ISSN":["0738-081X"],"issn-type":[{"value":"0738-081X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of neuropeptides in the control of regional immunity","name":"articletitle","label":"Article Title"},{"value":"Clinics in Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clindermatol.2014.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}