{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T03:01:14Z","timestamp":1778036474571,"version":"3.51.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","cidjournal.com","clinicalkey.es","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Dermatology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.clindermatol.2015.05.003","type":"journal-article","created":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T00:37:34Z","timestamp":1432859854000},"page":"527-530","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Pyoderma gangrenosum\u2014a systemic disease?"],"prefix":"10.1016","volume":"33","author":[{"given":"Uwe","family":"Wollina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clindermatol.2015.05.003_bb0005","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1001\/archderm.1930.01440160053009","article-title":"Pyoderma [ecthyma] gangrenosum: clinical and experimental observations in five cases occurring in adults","volume":"22","author":"Brunsting","year":"1930","journal-title":"Arch Dermatol Syphilol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0010","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1750-1172-2-19","article-title":"Pyoderma gangrenosum\u2014a review","volume":"2","author":"Wollina","year":"2007","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0015","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1038\/jid.2012.130","article-title":"Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study","volume":"132","author":"Langan","year":"2012","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0020","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/1750-1172-8-136","article-title":"Associated factors and comorbidities in patients with pyoderma gangrenosum in Germany: a retrospective multicentric analysis in 259 patients","volume":"8","author":"Al Ghazal","year":"2013","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0025","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/j.1365-2133.2011.10565.x","article-title":"Pyoderma gangrenosum: a retrospective review of patient characteristics, comorbidities and therapy in 103 patients","volume":"165","author":"Binus","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0030","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/BOR.0b013e328341152f","article-title":"Pyoderma gangrenosum","volume":"23","author":"Wollina","year":"2011","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0035","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s10354-014-0285-x","article-title":"Pyoderma gangrenosum \u2013 pathogenetic oriented treatment approaches","volume":"164","author":"Wollina","year":"2014","journal-title":"Wien Med Wochenschr"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0040","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1007\/s00108-013-3342-4","article-title":"Ulcus cruris","volume":"54","author":"Wollina","year":"2013","journal-title":"Internist (Berl)"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0045","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1684\/ejd.2013.2018","article-title":"Pyoderma gangrenosum and concomitant hidradenitis suppurativa-rapid response to canakinumab (anti-IL-1 \u03b2)","volume":"23","author":"Jaeger","year":"2013","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0050","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4103\/2229-5178.105454","article-title":"Acne inversa (Hidradenitis suppurativa): a review with a focus on pathogenesis and treatment","volume":"4","author":"Wollina","year":"2013","journal-title":"Indian Dermatol Online J"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0055","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1468-3083.2010.03937.x","article-title":"Acne-associated syndromes: models for better understanding of acne pathogenesis","volume":"25","author":"Chen","year":"2011","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0060","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1111\/1346-8138.12463","article-title":"Pyoderma gangrenosum with corneal perforation by Mooren's ulcer","volume":"41","author":"Nigi","year":"2014","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0065","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3109\/01676830.2013.851250","article-title":"Management of cicatricialectropion secondary to pyoderma gangrenosum","volume":"33","author":"Thampy","year":"2014","journal-title":"Orbit"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0070","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1159\/000356100","article-title":"Facial pyodermagangrenosum in senescence","volume":"5","author":"Kratzsch","year":"2013","journal-title":"Case Rep Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0075","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s12348-012-0083-9","article-title":"Retinal vasculitis associated with pyoderma gangrenosum: a case report","volume":"2","author":"Yuksel","year":"2012","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0080","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3109\/01676830.2011.648810","article-title":"Refractory pyoderma gangrenosum of the orbit and the lacrimal sac","volume":"31","author":"Cordero-Coma","year":"2012","journal-title":"Orbit"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0085","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1684\/ejd.2013.1968","article-title":"Pyoderma gangrenosum with severe cutaneous and oral involvement","volume":"23","author":"Marzano","year":"2013","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0090","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3315\/jdcr.2011.1070","article-title":"Photoletter to the editor: oral ulceration in pyoderma gangrenosum","volume":"5","author":"Verma","year":"2011","journal-title":"J Dermatol Case Rep"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2310\/7750.2014.13196","article-title":"Fatal case of vulvar pyoderma gangrenosum with pulmonary involvement: case presentation and literature review","volume":"18","author":"Mercer","year":"2014","journal-title":"J Cutan Med Surg"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0100","first-page":"4","article-title":"A case of ulcerative colitis presenting as pyoderma gangrenosum and lung nodule","author":"Li","year":"2014","journal-title":"J Community Hosp Intern Med Perspect"},{"issue":"6 Suppl 1","key":"10.1016\/j.clindermatol.2015.05.003_bb0105","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1590\/abd1806-4841.20132448","article-title":"Pyoderma gangrenosum with renal and splenic impairment\u2013case report","volume":"88","author":"Carvalho","year":"2013","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0110","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/pde.12138","article-title":"Pediatric pyoderma gangrenosum with splenic and pulmonary involvement","volume":"30","author":"Allen","year":"2013","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0115","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.annder.2013.12.003","article-title":"Mucocutaneous pyoderma gangrenosum mimicking cervical cellulitis infection","volume":"141","author":"Daoui","year":"2014","journal-title":"Ann Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0120","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.clindermatol.2013.08.024","article-title":"Nonspecific genital ulcers","volume":"32","author":"Sehgal","year":"2014","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0125","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/ans.12394","article-title":"Pyoderma gangrenosum of the penis: an important lesson","volume":"85","author":"Ng","year":"2015","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0130","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1111\/1346-8138.12252","article-title":"Genital pyoderma gangrenosum: report of two cases and published work review of Japanese cases","volume":"40","author":"Satoh","year":"2013","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0135","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00404-012-2692-9","article-title":"Pyoderma gangrenosum of the vaginal vault after vaginal hysterectomy: only the correct diagnosis of a rare entity can prevent long-term morbidity","volume":"288","author":"G\u00fcth","year":"2013","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0140","first-page":"E14","article-title":"Osteomyelitis in association with pyoderma gangrenosum and ulcerative colitis","volume":"93","author":"Maejima","year":"2014","journal-title":"Cutis"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0145","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s13555-014-0044-3","article-title":"Severe back pain in a young patient with pyoderma gangrenosum and Crohn's disease controlled with anti-tumor necrosis factor therapy: sterile osteomyelitis","volume":"4","author":"Felton","year":"2014","journal-title":"Dermatol Ther (Heidelb)"},{"key":"10.1016\/j.clindermatol.2015.05.003_bb0150","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jhsa.2012.10.049","article-title":"Pyoderma gangrenosum with wrist joint destruction: Case report","volume":"38","author":"Choe","year":"2013","journal-title":"J Hand Surg [Am]"}],"container-title":["Clinics in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0738081X15001182?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0738081X15001182?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T07:43:36Z","timestamp":1717919016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0738081X15001182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0738081X15001182"],"URL":"https:\/\/doi.org\/10.1016\/j.clindermatol.2015.05.003","relation":{},"ISSN":["0738-081X"],"issn-type":[{"value":"0738-081X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pyoderma gangrenosum\u2014a systemic disease?","name":"articletitle","label":"Article Title"},{"value":"Clinics in Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clindermatol.2015.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}