{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T11:33:52Z","timestamp":1782473632730,"version":"3.54.5"},"reference-count":170,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Dermatology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.clindermatol.2017.06.004","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T04:15:20Z","timestamp":1498536920000},"page":"421-434","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":96,"title":["Beh\u00e7et disease: New aspects"],"prefix":"10.1016","volume":"35","author":[{"given":"Isil","family":"Bulur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meltem","family":"Onder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clindermatol.2017.06.004_bb0005","first-page":"1152","article-title":"\u00dcber rezidivierende aphth\u00f6se, durch ein Virus verursachte Geschw\u00fcre am Mund, am Auge und an den Genitalien","volume":"105","author":"Beh\u00e7et","year":"1937","journal-title":"Dermatol Monatsschr"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0010","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.berh.2008.08.005","article-title":"Beh\u00e7et\u2019s syndrome","volume":"22","author":"Yurdakul","year":"2008","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0015","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1177\/10454411980090030401","article-title":"Recurrent aphthous stomatitis","volume":"9","author":"Porter","year":"1998","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0020","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/j.1601-0825.2011.01840.x","article-title":"Urban legends: Recurrent aphthous stomatitis","volume":"17","author":"Baccaglini","year":"2011","journal-title":"Oral Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0025","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0190-9622(85)70147-8","article-title":"Complex aphthosis: A forme fruste of Beh\u00e7et\u2019s syndrome?","volume":"13","author":"Jorizzo","year":"1985","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0030","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/MD.0b013e318211bf28","article-title":"Beh\u00e7et disease: Evolution of clinical manifestations","volume":"90","author":"Ideguchi","year":"2011","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0035","doi-asserted-by":"crossref","first-page":"423","DOI":"10.3349\/ymj.1997.38.6.423","article-title":"Clinical manifestations of Beh\u00e7et\u2019s disease. An analysis of 2147 patients","volume":"38","author":"G\u00fcrler","year":"1997","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0040","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1111\/j.1365-2133.2007.08116.x","article-title":"Clinical features and natural course of Beh\u00e7et\u2019s disease in 661 cases: A multicenter study","volume":"157","author":"Alpsoy","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0045","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1046\/j.1365-4362.2003.01893.x","article-title":"Prevalence of Beh\u00e7et\u2019s disease in Istanbul, Turkey","volume":"42","author":"Azizlerli","year":"2003","journal-title":"Int J Dermatol"},{"issue":"4 Suppl. 34","key":"10.1016\/j.clindermatol.2017.06.004_bb0050","first-page":"53","article-title":"Prevalence of Beh\u00e7et\u2019s disease in rural western Turkey: A preliminary report","volume":"22","author":"Cakir","year":"2004","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0055","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1076\/opep.9.5.325.10338","article-title":"The prevalence of Beh\u00e7et\u2019s disease above the age of 10 years: The results of a pilot study conducted at the Park Primary Health Care Center in Ankara, Turkey","volume":"9","author":"Idil","year":"2002","journal-title":"Ophthalmic Epidemiol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0060","first-page":"820","article-title":"The prevalence of Beh\u00e7et\u2019s syndrome in a rural area in northern Turkey","volume":"15","author":"Yurdakul","year":"1988","journal-title":"J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0065","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3349\/ymj.1997.38.6.411","article-title":"Epidemiological features of Adamantiades-Beh\u00e7et\u2019s disease in Germany and in Europe","volume":"38","author":"Zouboulis","year":"1997","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0070","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1136\/ard.43.6.783","article-title":"Influence of age of onset and patient\u2019s sex on the prevalence and severity of manifestations of Beh\u00e7et\u2019s syndrome","volume":"43","author":"Yazici","year":"1984","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0075","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1046\/j.1365-4362.2003.01741.x","article-title":"Evaluation of clinical findings according to sex in 2313 Turkish patients with Beh\u00e7et\u2019s disease","volume":"42","author":"Tursen","year":"2003","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0080","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/0-306-48382-3_11","article-title":"The influence of gender on the frequency of clinical symptoms in Beh\u00e7et\u2019s disease","volume":"528","author":"Davatchi","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0085","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/0-306-48382-3_10","article-title":"Influence of sex on patients with Beh\u00e7et\u2019s disease in Korea","volume":"528","author":"Bang","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0090","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1600-0528.2007.00329.x","article-title":"Risk indicators for recurrent aphthous ulcers among adults in the US","volume":"35","author":"Chattopadhyay","year":"2007","journal-title":"Community Dent Oral Epidemiol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0095","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/S1085-5629(97)80017-X","article-title":"Recurrent aphthous stomatitis: Clinical characteristics and associated systemic disorders","volume":"16","author":"Rogers","year":"1997","journal-title":"Semin Cutan Med Surg"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0100","doi-asserted-by":"crossref","first-page":"200","DOI":"10.14219\/jada.archive.2003.0134","article-title":"The diagnosis and management of recurrent aphthous stomatitis: A consensus approach","volume":"134","author":"Scully","year":"2003","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0105","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00296-006-0281-6","article-title":"Immunopathogenesis of Beh\u00e7et\u2019s disease with special emphasize to the possible role of antigen presenting cells","volume":"27","author":"Pay","year":"2007","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0110","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1007\/s00296-007-0367-9","article-title":"Pro-inflammatory cellular immune response in Beh\u00e7et\u2019s disease","volume":"27","author":"Kulaber","year":"2007","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0115","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.2165\/11641370-000000000-00000","article-title":"Beh\u00e7et\u2019s syndrome","volume":"72","author":"Dalvi","year":"2012","journal-title":"Drugs"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0120","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/RHU.0000000000000100","article-title":"Successful management of refractory pediatric-onset complex aphthosis with lenalidomide","volume":"20","author":"Kalampokis","year":"2014","journal-title":"J Clin Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1601-0825.2005.01143.x","article-title":"Mucosal disease series. Number VI. Recurrent aphthous stomatitis","volume":"12","author":"Jurge","year":"2006","journal-title":"Oral Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0130","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.autrev.2009.10.005","article-title":"Etiopathogenesis of Beh\u00e7et\u2019s disease","volume":"9","author":"Mendoza-Pinto","year":"2010","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0135","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0198-8859(96)00122-X","article-title":"HLA-C genotyping of patients with Beh\u00e7et\u2019s disease in the Japanese population","volume":"50","author":"Mizuki","year":"1996","journal-title":"Hum Immunol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0140","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1399-0039.1981.tb00687.x","article-title":"Beh\u00e7et\u2019s disease: Lack of correlation of clinical manifestations with HLA antigens","volume":"17","author":"Muftuoglu","year":"1981","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0145","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.autrev.2011.11.026","article-title":"New insights into the pathogenesis of Beh\u00e7et\u2019s disease","volume":"11","author":"Pineton de Chambrun","year":"2012","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0150","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1177\/2040622314523062","article-title":"Update on the therapy of Beh\u00e7et disease","volume":"5","author":"Saleh","year":"2014","journal-title":"Ther Adv Chronic Dis"},{"issue":"5 Suppl. 24","key":"10.1016\/j.clindermatol.2017.06.004_bb0155","first-page":"6","article-title":"Beh\u00e7et\u2019s disease: An update on the pathogenesis","volume":"19","author":"G\u00fcl","year":"2001","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0160","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/ar2695","article-title":"Identification of novel genetic susceptibility loci for Beh\u00e7et\u2019s disease using a genome-wide association study","volume":"11","author":"Fei","year":"2009","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0165","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1099\/00222615-34-1-39","article-title":"Detection of HSV-1 DNA in patients with Beh\u00e7et\u2019s syndrome and in patients with recurrent oral ulcers by the polymerase chain reaction","volume":"34","author":"Studd","year":"1991","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0170","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1111\/bjd.12128","article-title":"Serum IgA reactivity against GroEL of Streptococcus sanguinis and human heterogeneous nuclear ribonucleoprotein A2\/B1 in patients with Beh\u00e7et disease","volume":"168","author":"Cho","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0175","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1600-051X.2007.01085.x","article-title":"Relationship between periodontal findings and Beh\u00e7et\u2019s disease: A controlled study","volume":"34","author":"Akman","year":"2007","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0180","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1128\/IAI.59.4.1434-1441.1991","article-title":"Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Beh\u00e7et\u2019s disease","volume":"59","author":"Lehner","year":"1991","journal-title":"Infect Immun"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0185","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00002281-200401000-00008","article-title":"Beh\u00e7et\u2019s syndrome","volume":"16","author":"Yurdakul","year":"2004","journal-title":"Curr Opin Rheumatol"},{"issue":"4 Suppl. 67","key":"10.1016\/j.clindermatol.2017.06.004_bb0190","first-page":"71","article-title":"Th17 cells in Beh\u00e7et\u2019s disease: A new immunoregulatory axis","volume":"29","author":"Hamzaoui","year":"2011","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0195","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s00296-005-0029-8","article-title":"Serum interleukin-18 levels in patients with Beh\u00e7et\u2019s disease. Is its expression associated with disease activity or clinical presentations?","volume":"26","author":"Musabak","year":"2006","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0200","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jaci.2011.05.029","article-title":"Critical role of IL-21 in modulating TH17 and regulatory T cells in Beh\u00e7et disease","volume":"128","author":"Geri","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0205","doi-asserted-by":"crossref","first-page":"3058","DOI":"10.1167\/iovs.07-1390","article-title":"Upregulated IL-23 and IL-17 in Beh\u00e7et patients with active uveitis","volume":"49","author":"Chi","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0210","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.lfs.2012.03.017","article-title":"Interactions between IL17A, IL23R, and STAT4 polymorphisms confer susceptibility to intestinal Beh\u00e7et\u2019s disease in Korean population","volume":"90","author":"Kim","year":"2012","journal-title":"Life Sci"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0215","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/030097402320318387","article-title":"Cytokine profile in Beh\u00e7et\u2019s disease, relationship with disease activity","volume":"31","author":"Hamzaoui","year":"2002","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0220","doi-asserted-by":"crossref","first-page":"554","DOI":"10.4049\/jimmunol.168.2.554","article-title":"Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines","volume":"168","author":"Zarember","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0225","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1365-2230.2004.01684.x","article-title":"Serum interleukin 18 and tumour necrosis factor-alpha levels are increased in Behcet\u2019s disease","volume":"30","author":"Oztas","year":"2005","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0230","doi-asserted-by":"crossref","first-page":"6012","DOI":"10.1167\/iovs.13-12159","article-title":"Higher expression of Toll-like receptors 2,3, 4, and 8 in ocular Behcet\u2019s disease","volume":"54","author":"Liu","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0235","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1365-2230.2004.01488.x","article-title":"Erythrocyte superoxide dismutase, catalase activities and plasma nitrite and nitrate levels in patients with Beh\u00e7et\u2019s disease and recurrent aphthous stomatitis","volume":"29","author":"Gunduz","year":"2004","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0240","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1365-2133.2004.06003.x","article-title":"Increased advanced oxidation protein products in Beh\u00e7et\u2019s disease: A new activity marker?","volume":"151","author":"Yazici","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0245","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1468-3083.2003.t01-1-00574.x","article-title":"Nitric oxide levels in Behcet disease","volume":"17","author":"Sancak","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0250","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/clin.1993.1059","article-title":"Antibodies to endothelial cells in patients with Beh\u00e7et\u2019s disease","volume":"67","author":"Aydintug","year":"1993","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0255","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF02208085","article-title":"Antiendothelial cell antibodies, endothelial proliferation and von Willebrand factor antigen in Beh\u00e7et\u2019s disease","volume":"14","author":"Direskeneli","year":"1995","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0260","first-page":"87","article-title":"Anti-Saccharomyces cerevisiae antibodies in Beh\u00e7et\u2019s disease\u2014a familial study","volume":"24","author":"Monselise","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0265","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/rheumatology\/40.2.192","article-title":"Anticardiolipin antibodies in Beh\u00e7et\u2019s disease: A reassessment","volume":"40","author":"Tokay","year":"2001","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0270","first-page":"80","article-title":"Antikinectin autoantibody in Beh\u00e7et\u2019s disease and several other autoimmune connective tissue diseases","volume":"25","author":"Feng","year":"2007","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0275","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s00296-002-0274-z","article-title":"Antiannexin V autoantibody in thrombophilic Beh\u00e7et\u2019s disease","volume":"24","author":"Aslan","year":"2004","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0280","first-page":"67","article-title":"Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Beh\u00e7et\u2019s disease","volume":"27","author":"Vural","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0285","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0049-3848(02)00006-3","article-title":"Pathological haemostasis and \u201cprothrombotic state\u201d in Beh\u00e7et\u2019s disease","volume":"105","author":"Kiraz","year":"2002","journal-title":"Thromb Res"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0290","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1365-2133.1989.tb08213.x","article-title":"Cutaneous fibrinolytic potential, tPA dependent, is reduced in Beh\u00e7et\u2019s disease","volume":"121","author":"Lotti","year":"1989","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0295","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/01.icu.0000247411.59213.bb","article-title":"Beh\u00e7et\u2019s disease: General concepts and recent advances","volume":"17","author":"Okada","year":"2006","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0300","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jaad.2013.09.013","article-title":"Serum endocan levels as a marker of disease activity in patients with Beh\u00e7et disease","volume":"70","author":"Balta","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0305","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/rheumatology\/keh561","article-title":"Polymorphisms in the endothelial nitric oxide synthase gene are associated with Beh\u00e7et\u2019s disease","volume":"44","author":"Karasneh","year":"2005","journal-title":"Rheumatology"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0310","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jbspin.2014.06.007","article-title":"Ischemia-modified albumin (IMA): A novel marker of vascular involvement in Beh\u00e7et\u2019s disease?","volume":"82","author":"Capkin","year":"2015","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0315","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00005-013-0261-y","article-title":"Etiopathogenesis of recurrent aphthous stomatitis and the role of immunologic aspects: Literature review","volume":"62","author":"Slebioda","year":"2014","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0320","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.0904-2512.2004.00089.x","article-title":"The Th1\/Th2 immunotype response of the recurrent aphthous ulceration analyzed by cDNA microarray","volume":"33","author":"Borra","year":"2004","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0325","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1001\/archderm.134.7.827","article-title":"Elevated levels of interferon gamma, tumor necrosis factor alpha, interleukins 2,4 and 5, but not interleukin 10, are present in recurrent aphthous stomatitis","volume":"134","author":"Buno","year":"1998","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0330","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.imlet.2005.01.002","article-title":"Predominance of type 1 cytokines and decreased number of CD4(+)CD25(+high) T regulatory cells in peripheral blood of patients with recurrent aphthous ulcerations","volume":"99","author":"Lewkowicz","year":"2005","journal-title":"Immunol Lett"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0335","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1080\/03009740600905380","article-title":"Expression of cytokines, chemokines, and chemokine receptors in oral ulcers of patients with Beh\u00e7et\u2019s disease (BD) and recurrent aphthous stomatitis is Th1-associated, although Th2-association is also observed in patients with BD","volume":"35","author":"Dalghous","year":"2006","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0340","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1600-0714.2008.00665.x","article-title":"Immune-expression of HSP27 and IL-10 in recurrent aphthous ulceration","volume":"37","author":"Miyamoto","year":"2008","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0345","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.clindermatol.2013.01.002","article-title":"Beh\u00e7et\u2019s syndrome: facts and controversies","volume":"31","author":"Mat","year":"2013","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0350","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.jaad.2007.10.452","article-title":"Demographic and clinical properties of juvenile-onset Beh\u00e7et\u2019s disease: A controlled multicenter study","volume":"58","author":"Karincaoglu","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0355","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1346-8138.2003.tb00423.x","article-title":"The clinical course of Beh\u00e7et\u2019s disease in pregnancy: A retrospective analysis and review of the literature","volume":"30","author":"Uzun","year":"2003","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0360","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1002\/art.38052","article-title":"Beh\u00e7et\u2019s disease and pregnancy","volume":"65","author":"Noel","year":"2013","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0365","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/0-306-48382-3_17","article-title":"Chronology of clinical manifestations in Beh\u00e7et\u2019s disease. Analysis of 4024 cases","volume":"528","author":"Shahram","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0370","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1756-185X.2010.01549.x","article-title":"Beh\u00e7et\u2019s disease in Iran: Analysis of 6500 cases","volume":"13","author":"Davatchi","year":"2010","journal-title":"Int J Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0375","doi-asserted-by":"crossref","first-page":"637","DOI":"10.3109\/14397595.2013.844400","article-title":"Clinical features of Beh\u00e7et\u2019s disease in patients without oral aphthosis","volume":"24","author":"Faezi","year":"2014","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0380","doi-asserted-by":"crossref","first-page":"573","DOI":"10.3349\/ymj.2007.48.4.573","article-title":"Mucocutaneous lesions of Beh\u00e7et\u2019s disease","volume":"48","author":"Alpsoy","year":"2007","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0385","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/rheumatology\/31.11.767","article-title":"Clinical differentiation of oral ulceration in Beh\u00e7et\u2019s disease","volume":"31","author":"Main","year":"1992","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0390","doi-asserted-by":"crossref","first-page":"428","DOI":"10.3349\/ymj.1997.38.6.428","article-title":"Epidemiological and clinical features of Beh\u00e7et\u2019s disease in Korea","volume":"38","author":"Bang","year":"1997","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0395","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/0-306-48382-3_61","article-title":"Complex aphthosis","volume":"528","author":"Rogers","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0400","first-page":"1078","article-title":"Criteria for diagnosis of Beh\u00e7et\u2019s disease","volume":"335","author":"International Study Group for Beh\u00e7et\u2019s Disease","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0405","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1007\/s100670070020","article-title":"Smoking and Beh\u00e7et\u2019s disease","volume":"19","author":"Soy","year":"2000","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0410","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/0-306-48382-3_64","article-title":"The effect of smoking on the clinical features of Adamantiades-Beh\u00e7et\u2019s disease","volume":"528","author":"Kaklamani","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0415","first-page":"354","article-title":"Review of the chronology of clinical manifestations in 60 patients with Beh\u00e7et\u2019s disease","volume":"2003","author":"Alpsoy","year":"2007","journal-title":"Dermatology"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0420","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1007\/s00296-014-3011-5","article-title":"Genital aphthosis in Beh\u00e7et\u2019s disease: Is it associated with less eye involvement?","volume":"34","author":"Faezi","year":"2014","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0425","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/j.1365-4632.2006.02859.x","article-title":"The frequency of scarring after genital ulcers in Beh\u00e7et\u2019s syndrome: A prospective study","volume":"45","author":"Mat","year":"2006","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0430","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jaad.2009.08.038","article-title":"Reactive nonsexually related acute genital ulcers: review of cases evaluated at Mayo Clinic","volume":"63","author":"Lehman","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0435","doi-asserted-by":"crossref","first-page":"286","DOI":"10.2340\/0001555572286","article-title":"A new kind of skin lesion in Beh\u00e7et\u2019s disease: Extragenital ulcerations","volume":"72","author":"Azizlerli","year":"1992","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0440","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1309\/GCTH-0060-55K8-XCTT","article-title":"Clinicopathologic evaluation of nodular cutaneous lesions of Beh\u00e7et syndrome","volume":"116","author":"Demirkesen","year":"2001","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0445","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1046\/j.1365-4362.1998.00401.x","article-title":"A randomized, controlled and blinded study of papulopustular lesions in Turkish Beh\u00e7et\u2019s patients","volume":"37","author":"Alpsoy","year":"1998","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0450","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1046\/j.1468-3083.2003.00625.x","article-title":"Histological and immunofluorescence findings of non-follicular papulopustular lesions in patients with Beh\u00e7et\u2019s disease","volume":"17","author":"Alpsoy","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0455","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1136\/ard.60.11.1074","article-title":"Papulopustular skin lesions are seen more frequently in patients with Beh\u00e7et\u2019s syndrome who have arthritis: A controlled and masked study","volume":"60","author":"Diri","year":"2001","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0460","first-page":"2393","article-title":"Target organ associations in Turkish patients with Beh\u00e7et\u2019s disease: A cross sectional study by explanatory factor analysis","volume":"29","author":"Tun\u00e7","year":"2002","journal-title":"J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0465","first-page":"4","article-title":"Cutaneous manifestation of Beh\u00e7et\u2019s disease","volume":"4","author":"Bulur","year":"2011","journal-title":"Turkiye Klinikleri J Dermatol-Special Topics"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0470","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/0-306-48382-3_109","article-title":"A case of Beh\u00e7et\u2019s disease with pathergy reaction at interferon injection site","volume":"528","author":"Aral","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0475","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s10067-011-1694-5","article-title":"Diagnostic value of pathergy test in Beh\u00e7et\u2019s disease according to the change of incidence over the time","volume":"30","author":"Davatchi","year":"2011","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0480","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3109\/s10165-012-0626-9","article-title":"Impact of the positive pathergy test on the performance of classification\/diagnosis criteria for Beh\u00e7et\u2019s disease","volume":"23","author":"Davatchi","year":"2013","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0485","doi-asserted-by":"crossref","first-page":"331","DOI":"10.2165\/11310790-000000000-00000","article-title":"Generalized Sweet syndrome lesions associated with Beh\u00e7et disease: A true association or simply co-morbidity?","volume":"10","author":"Karado\u011fan","year":"2009","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0490","first-page":"408","article-title":"Pyoderma gangrenosum associated with Beh\u00e7et\u2019s syndrome\u2014response to thalidomide","volume":"13","author":"Munro","year":"1988","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0495","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2340\/00015555-0221","article-title":"Vegetative pyoderma gangrenosum in Beh\u00e7et\u2019s disease","volume":"87","author":"Kim","year":"2007","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0500","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/archderm.138.5.698","article-title":"Raynaud phenomenon and Beh\u00e7et disease: Diagnosis with technetium Tc 99m methylene diphosphonate bone scan and treatment with continuous sympathetic block","volume":"138","author":"Onder","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0505","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/MD.0b013e3182428f49","article-title":"Spectrum of cardiac lesions in Beh\u00e7et disease: A series of 52 patients and review of the literature","volume":"91","author":"Geri","year":"2012","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0510","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1093\/brain\/122.11.2171","article-title":"Clinical patterns of neurological involvement in Beh\u00e7et\u2019s disease: Evaluation of 200 patients","volume":"122","author":"Akman-Demir","year":"1999","journal-title":"Brain"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0515","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S1474-4422(09)70015-8","article-title":"Neuro-Beh\u00e7et\u2019s disease: epidemiology, clinical characteristics, and management","volume":"8","author":"Al-Araji","year":"2009","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0520","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000051756","article-title":"Depression, anxiety levels and general psychological profile in Beh\u00e7et\u2019s disease","volume":"203","author":"Calikoglu","year":"2001","journal-title":"Dermatology"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0525","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1136\/ard.55.3.208","article-title":"Gastrointestinal involvement in Beh\u00e7et\u2019s syndrome: A controlled study","volume":"55","author":"Yurdakul","year":"1996","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0530","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1053\/gast.2001.22556","article-title":"Anti-tumor necrosis factor monoclonal antibody therapy for gastrointestinal Beh\u00e7et\u2019s disease: A case report","volume":"120","author":"Hassard","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0535","series-title":"Beh\u00e7et\u2019s Syndrome","first-page":"49","article-title":"Locomotor system disease in Beh\u00e7et\u2019s syndrome","author":"Yurdakul","year":"2010"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0540","first-page":"2219","article-title":"Fibromyalgia in Beh\u00e7et\u2019s syndrome","volume":"25","author":"Yavuz","year":"1998","journal-title":"J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0545","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/rheumatology\/40.2.212","article-title":"A reappraisal of amyloidosis in Beh\u00e7et\u2019s syndrome","volume":"40","author":"Melikoglu","year":"2001","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0550","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/MD.0b013e318242ff37","article-title":"Pulmonary artery involvement and associated lung disease in Beh\u00e7et disease: A series of 47 patients","volume":"91","author":"Seyahi","year":"2012","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0555","doi-asserted-by":"crossref","first-page":"607921","DOI":"10.1155\/2012\/607921","article-title":"Diagnosis\/classification criteria for Beh\u00e7et\u2019s disease","volume":"2012","author":"Davatchi","year":"2012","journal-title":"Pathol Res Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0560","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/jdv.12107","article-title":"The International Criteria for Beh\u00e7et\u2019s Disease (ICBD): A collaborative study of 27 countries on the sensitivity and specificity of the new criteria","volume":"28","author":"International Team for the Revision of the International Criteria for Beh\u00e7et\u2019s Disease (ITR-ICBD)","year":"2014","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0565","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.jaad.2004.10.863","article-title":"Complex aphthosis: A large case series with evaluation algorithm and therapeutic ladder from topicals to thalidomide","volume":"52","author":"Letsinger","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0570","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1529-8019.2010.01324.x","article-title":"Aphthous ulcers","volume":"23","author":"Messadi","year":"2010","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0575","first-page":"9","article-title":"New approaches in immunotherapy of beh\u00e7et disease","volume":"3","author":"Zare Shahneh","year":"2013","journal-title":"Adv Pharm Bull"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0580","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s00403-009-0990-2","article-title":"Beh\u00e7et\u2019s disease: An algorithmic approach to its treatment","volume":"301","author":"Alpsoy","year":"2009","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0585","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000182257","article-title":"Randomized trial of pimecrolimus cream plus colchicine tablets versus colchicine tablets in the treatment of genital ulcers in Beh\u00e7et\u2019s disease","volume":"218","author":"K\u00f6se","year":"2009","journal-title":"Dermatology"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0590","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1756-185X.2010.01531.x","article-title":"Pimecrolimus versus placebo in genital aphthous ulcers of Beh\u00e7et\u2019s disease: A randomized double-blind controlled trial","volume":"13","author":"Chams-Davatchi","year":"2010","journal-title":"Int J Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0595","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0030-4220(87)90310-0","article-title":"Clinical evaluation of benzydamine, chlorhexidine, and placebo mouthwashes in the management of recurrent aphthous stomatitis","volume":"63","author":"Matthews","year":"1987","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0600","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.bjoms.2007.07.201","article-title":"Oral mucosal disease: Recurrent aphthous stomatitis","volume":"46","author":"Scully","year":"2008","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0605","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/sj.bdj.4808250","article-title":"A clinical trial of prostaglandin E2 in recurrent aphthous ulceration","volume":"175","author":"Taylor","year":"1993","journal-title":"Br Dent J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0610","doi-asserted-by":"crossref","first-page":"871019","DOI":"10.1155\/2012\/871019","article-title":"New evidence-based treatment approach in Beh\u00e7et\u2019s disease","volume":"2012","author":"Alpsoy","year":"2012","journal-title":"Pathol Res Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0615","first-page":"532","article-title":"Beh\u00e7et\u2019s disease: Treatment of mucocutaneous lesions","volume":"23","author":"Alpsoy","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0620","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5070\/D31658K5FQ","article-title":"Topical minocycline and tetracycline rinses in treatment of recurrent aphthous stomatitis: A randomized cross-over study","volume":"13","author":"Gorsky","year":"2007","journal-title":"Dermatol Online J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0625","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archderm.135.5.529","article-title":"The use of sucralfate suspension in the treatment of oral and genital ulceration of Beh\u00e7et disease: A randomized, placebo-controlled, double-blind study","volume":"135","author":"Alpsoy","year":"1999","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0630","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/pho.2008.2274","article-title":"An evaluation of different treatments for recurrent aphthous stomatitis and patient perceptions: Nd:YAG laser versus medication","volume":"27","author":"Tezel","year":"2009","journal-title":"Photomed Laser Surg"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0635","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1111\/j.1600-0765.2008.01183.x","article-title":"Relationship between periodontal parameters and Beh\u00e7et\u2019s disease and evaluation of different treatments for oral recurrent aphthous stomatitis","volume":"44","author":"Arabaci","year":"2009","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0640","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1136\/ard.2007.080432","article-title":"EULAR recommendations for the management of Beh\u00e7et disease","volume":"67","author":"Hatemi","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0645","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/rheumatology\/kei165","article-title":"A double-blind trial of depot corticosteroids in Beh\u00e7et\u2019s syndrome","volume":"45","author":"Mat","year":"2006","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0650","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.survophthal.2005.04.009","article-title":"Current concepts in the etiology and treatment of Beh\u00e7et\u2019s disease","volume":"50","author":"Evereklioglu","year":"2005","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0655","first-page":"493","article-title":"Inefficacy of azapropazone in the acute arthritis of Beh\u00e7et\u2019s syndrome: A randomized, double blind, placebo controlled study","volume":"13","author":"Moral","year":"1995","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0660","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1365-4362.1991.tb05883.x","article-title":"Treatment of Beh\u00e7et disease with indomethacin","volume":"30","author":"Simsek","year":"1991","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0665","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1002\/1529-0131(200111)44:11<2686::AID-ART448>3.0.CO;2-H","article-title":"A double-blind trial of colchicine in Beh\u00e7et\u2019s syndrome","volume":"44","author":"Yurdakul","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0670","doi-asserted-by":"crossref","first-page":"542","DOI":"10.3109\/s10165-009-0200-2","article-title":"Colchicine versus placebo in Beh\u00e7et\u2019s disease: Randomized, double-blind, controlled crossover trial","volume":"19","author":"Davatchi","year":"2009","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0675","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.rdc.2013.02.010","article-title":"Beh\u00e7et\u2019s syndrome","volume":"39","author":"Hatemi","year":"2013","journal-title":"Rheum Dis Clin N Am"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0680","first-page":"928","article-title":"Interferon alfa combined with azathioprine for the uveitis of Beh\u00e7et\u2019s disease: An open study","volume":"4","author":"Hamuryudan","year":"2002","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0685","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1159\/000051781","article-title":"Mycophenolate mofetil is ineffective in the treatment of mucocutaneous Adamantiades-Beh\u00e7et\u2019s disease","volume":"203","author":"Adler","year":"2001","journal-title":"Dermatology"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0690","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/0-306-48382-3_114","article-title":"Efficacy of corticosteroids and cyclosporin in the treatment of retinal vasculitis inpatients with Beh\u00e7et\u2019s disease","volume":"528","author":"Ermakova","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0695","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1023\/A:1021227019915","article-title":"Long-term therapy with low dose cyclosporin A in ocular Beh\u00e7et\u2019s disease","volume":"105","author":"Ozdal","year":"2002","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0700","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1136\/ard.2008.087957","article-title":"Management of Beh\u00e7et disease: A systematic literature review for the European League Against Rheumatism evidence-based recommendations for the management of Beh\u00e7et disease","volume":"68","author":"Hatemi","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0705","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/ibd.20970","article-title":"Efficacy of oral tacrolimus on intestinal Beh\u00e7et\u2019s disease","volume":"16","author":"Matsumura","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0710","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0753-3322(01)00154-8","article-title":"Thalidomide in Beh\u00e7et\u2019s disease","volume":"56","author":"Shek","year":"2002","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0715","doi-asserted-by":"crossref","first-page":"443","DOI":"10.7326\/0003-4819-128-6-199803150-00004","article-title":"Thalidomide in the treatment of the mucocutaneous lesions of the Beh\u00e7et\u2019s syndrome","volume":"128","author":"Hamuryudan","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0720","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/MD.0b013e3181dfca14","article-title":"Use of thalidomide for severe recurrent aphthous stomatitis: A multicenter cohort analysis","volume":"89","author":"Hello","year":"2010","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0725","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0022-510X(98)00165-8","article-title":"Low-dose weekly methotrexate for progressive neuropsychiatric manifestations in Beh\u00e7et\u2019s disease","volume":"159","author":"Hirohata","year":"1998","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0730","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1346-8138.2002.tb00263.x","article-title":"Dapsone in Beh\u00e7et\u2019s disease: A double-blind, placebo-controlled, crossover study","volume":"29","author":"Sharquie","year":"2002","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0735","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/0-306-48382-3_120","article-title":"Pentoxifylline use for Beh\u00e7et\u2019s disease: The result of a survey among rheumatologist in North America","volume":"528","author":"Liang","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0740","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1136\/bjo.87.4.423","article-title":"Human recombinant interferon alfa-2a for the treatment of Beh\u00e7et\u2019s disease with sight threatening posterior uveitis","volume":"87","author":"K\u00f6tter","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0745","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1136\/bjo.2006.101550","article-title":"Efficacy of interferon alpha in the treatment of refractory and sight threatening uveitis: A retrospective monocentric study of 45 patients","volume":"91","author":"Bodaghi","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0750","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1001\/archderm.138.4.467","article-title":"Interferon alfa-2a in the treatment of Beh\u00e7et disease: A randomized, placebo controlled and double blind study","volume":"138","author":"Alpsoy","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0755","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2165\/00126839-200304010-00002","article-title":"Efficacy of rebamipide as adjunctive therapy in the treatment of recurrent oral aphthous ulcers in patients with Beh\u00e7et\u2019s disease: A randomised, double-blind, placebo-controlled study","volume":"4","author":"Matsuda","year":"2003","journal-title":"Drugs R D"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0760","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1346-8138.2006.00128.x","article-title":"Oral zinc sulfate in the treatment of Beh\u00e7et\u2019s disease: A double blind cross-over study","volume":"33","author":"Sharquie","year":"2006","journal-title":"J Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0765","first-page":"185","article-title":"Combination therapy with infliximab and methotrexate in recalcitrant mucocutaneous Beh\u00e7et disease","volume":"89","author":"Chan","year":"2012","journal-title":"Cutis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0770","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jaad.2009.02.044","article-title":"Infliximab treatment of severe genital ulcers associated with Beh\u00e7et disease","volume":"62","author":"Kasugai","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0775","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3109\/09273948.2013.781655","article-title":"Successful treatment with infliximab for Beh\u00e7et disease during pregnancy","volume":"21","author":"Takayama","year":"2013","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0780","first-page":"98","article-title":"Short-term trial of etanercept in Beh\u00e7et\u2019s disease: A double blind, placebo controlled study","volume":"32","author":"Melikoglu","year":"2005","journal-title":"J Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0785","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s00296-009-1104-3","article-title":"Successful treatment with adalimumab in a patient with coexisting Beh\u00e7et\u2019s disease and ankylosing spondylitis","volume":"30","author":"Yildiz","year":"2010","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0790","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3109\/09273948.2012.741744","article-title":"Beh\u00e7et disease-associated uveitis successfully treated with golimumab","volume":"21","author":"Mesquida","year":"2013","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0795","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1136\/annrheumdis-2011-155143","article-title":"Interleukin-1\u03b2-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Beh\u00e7et\u2019s disease: An open-label pilot study","volume":"71","author":"G\u00fcl","year":"2012","journal-title":"Ann Rheum Dis"},{"issue":"3 Suppl. 72","key":"10.1016\/j.clindermatol.2017.06.004_bb0800","first-page":"115","article-title":"Successful use of canakinumab in a patient with resistant Beh\u00e7et\u2019s disease","volume":"30","author":"Cantarini","year":"2012","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0805","doi-asserted-by":"crossref","first-page":"284","DOI":"10.7326\/0003-4819-149-4-200808190-00018","article-title":"Resistant Beh\u00e7et disease responsive to Anakinra","volume":"149","author":"Botsios","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0810","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.clineuro.2011.10.024","article-title":"Tocilizumab treatment for neuro-Beh\u00e7et\u2019s disease, the first report","volume":"114","author":"Shapiro","year":"2012","journal-title":"Clin Neurol Neurosurg"},{"issue":"3 Suppl. 72","key":"10.1016\/j.clindermatol.2017.06.004_bb0815","first-page":"73","article-title":"Refractory neuro-Beh\u00e7et treated by tocilizumab: A case report","volume":"30","author":"Urbaniak","year":"2012","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0820","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3109\/s10165-011-0497-5","article-title":"A case of Beh\u00e7et\u2019s disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab","volume":"22","author":"Hirano","year":"2012","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0825","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1093\/rheumatology\/ket130","article-title":"Lack of efficacy of tocilizumab in mucocutaneous Behcet`s Syndrome; reported of two cases","volume":"52","author":"Diamantopoulos","year":"2013","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0830","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/j.1756-185X.2010.01546.x","article-title":"Rituximab in intractable ocular lesions of Beh\u00e7et\u2019s disease; randomized single-blind control study (pilot study)","volume":"13","author":"Davatchi","year":"2010","journal-title":"Int J Rheum Dis"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0835","doi-asserted-by":"crossref","first-page":"306","DOI":"10.3109\/s10165-008-0057-9","article-title":"Treatment of retinal vasculitis in Beh\u00e7et\u2019s disease with rituximab","volume":"18","author":"Sadreddini","year":"2008","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0840","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/RHU.0b013e318284735c","article-title":"Remission induction in a case of refractory Beh\u00e7et disease with alemtuzumab","volume":"19","author":"Perez-Pampin","year":"2013","journal-title":"J Clin Rheumatol"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0845","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/09273940701299370","article-title":"A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications","volume":"15","author":"Buggage","year":"2007","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.clindermatol.2017.06.004_bb0850","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1046\/j.1468-3083.2001.00251.x","article-title":"The multiple faces of Beh\u00e7et\u2019s disease and its aetiological factors","volume":"15","author":"Onder","year":"2001","journal-title":"J Eur Acad Dermatol Venereol"}],"container-title":["Clinics in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0738081X17301001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0738081X17301001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T05:06:52Z","timestamp":1692853612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0738081X17301001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":170,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S0738081X17301001"],"URL":"https:\/\/doi.org\/10.1016\/j.clindermatol.2017.06.004","relation":{},"ISSN":["0738-081X"],"issn-type":[{"value":"0738-081X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Beh\u00e7et disease: New aspects","name":"articletitle","label":"Article Title"},{"value":"Clinics in Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clindermatol.2017.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}