{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:51:16Z","timestamp":1788871876251,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["013758"],"award-info":[{"award-number":["013758"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.clineuro.2010.04.018","type":"journal-article","created":{"date-parts":[[2010,5,19]],"date-time":"2010-05-19T02:50:25Z","timestamp":1274237425000},"page":"653-657","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Varicella zoster virus in progressive forms of multiple sclerosis"],"prefix":"10.1016","volume":"112","author":[{"given":"Graciela","family":"Ordo\u00f1ez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"Martinez-Palomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Corona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Pineda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Flores-Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bibiana","family":"Chavez-Munguia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Sotelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clineuro.2010.04.018_bib1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1034\/j.1600-0404.2002.1o077.x","article-title":"Varicella ephemeral breastfeeding and eczema as risk factors for multiple sclerosis in Mexicans","volume":"105","author":"Tarrats","year":"2002","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.clineuro.2010.04.018_bib2","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1600-0404.2005.00491.x","article-title":"Frequent association of multiple sclerosis with varicella and zoster","volume":"112","author":"Perez-Cesari","year":"2005","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.clineuro.2010.04.018_bib3","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s00415-006-0402-x","article-title":"Varicella-zoster virus at relapses of multiple sclerosis","volume":"254","author":"Sotelo","year":"2007","journal-title":"J Neurol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib4","series-title":"Diseases of the nervous system","first-page":"1660","article-title":"Viral diseases of the nervous system","author":"Davis","year":"2002"},{"key":"10.1016\/j.clineuro.2010.04.018_bib5","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/ana.21316","article-title":"Varicella-zoster virus in cerebrospinal fluid at relapses of multiple sclerosis","volume":"63","author":"Sotelo","year":"2008","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib6","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1056\/NEJM200009283431307","article-title":"Multiple sclerosis","volume":"343","author":"Noseworthy","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clineuro.2010.04.018_bib7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jns.2007.07.001","article-title":"On the viral hypothesis of multiple sclerosis: participation of varicella-zoster virus","volume":"262","author":"Sotelo","year":"2007","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.clineuro.2010.04.018_bib8","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archneur.61.4.529","article-title":"Brief presence of varicella zoster viral DNA in mononuclear cells during relapses of multiple sclerosis","volume":"61","author":"Ordo\u00f1ez","year":"2004","journal-title":"Arch Neurol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib9","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.clineuro.2008.07.007","article-title":"Association of a history of varicella virus infection with multiple sclerosis","volume":"111","author":"Rodr\u00edguez-Violante","year":"2009","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.clineuro.2010.04.018_bib10","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1056\/NEJMra020100","article-title":"The effect of infections on susceptibility to autoimmune and allergic diseases","volume":"347","author":"Bach","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clineuro.2010.04.018_bib11","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.4049\/jimmunol.169.3.1550","article-title":"Bystander CD8 T cell-mediated demyelination after viral infection of the central nervous system","volume":"169","author":"Haring","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib12","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S1474-4422(07)70267-3","article-title":"The neurotropic herpes viruses: herpes simplex and varicella-zoster","volume":"6","author":"Steiner","year":"2007","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib13","series-title":"Varicella-zoster virus: virology and clinical management","first-page":"123","article-title":"Pathogenesis of latency and reactivation in varicella-zoster virus virology and clinical management","author":"Silverstein","year":"2000"},{"key":"10.1016\/j.clineuro.2010.04.018_bib14","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1056\/NEJM200003023420906","article-title":"Neurologic complications of the reactivation of varicella-zoster virus","volume":"342","author":"Gilden","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clineuro.2010.04.018_bib15","first-page":"41","article-title":"Human herpes viruses in MS","volume":"14","author":"Christensen","year":"2007","journal-title":"Int MS J"},{"key":"10.1016\/j.clineuro.2010.04.018_bib16","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1353\/pbm.1996.0058","article-title":"Multiple viral pathogenicity. Another paradigm in medical research?","volume":"39","author":"Sotelo","year":"1996","journal-title":"Perspect Biol Med"},{"key":"10.1016\/j.clineuro.2010.04.018_bib17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1600-0404.1997.tb00258.x","article-title":"Multiple sclerosis in the Faroe Islands. 7. Results of a case control questionnaire with multiple controls","volume":"96","author":"Kurtzke","year":"1997","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.clineuro.2010.04.018_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0895-4356(00)00268-7","article-title":"Multiple sclerosis in the Faroe Islands: an epitome","volume":"54","author":"Kurtzke","year":"2001","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib19","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0140-6736(08)60145-2","article-title":"Genes for multiple sclerosis","volume":"371","author":"Ramagopalan","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.clineuro.2010.04.018_bib20","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1056\/NEJMp0708085","article-title":"The new age of molecular diagnostics for microbial agents","volume":"358","author":"Whitley","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clineuro.2010.04.018_bib21","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/ana.21605","article-title":"Varicella zoster virus is not a disease-relevant antigen in multiple sclerosis","volume":"65","author":"Burgoon","year":"2009","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib22","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/jmv.20777","article-title":"Increased prevalence of varicella zoster virus DNA in cerebrospinal fluid from patients with multiple sclerosis","volume":"79","author":"Mancuso","year":"2007","journal-title":"J Med Virol"},{"key":"10.1016\/j.clineuro.2010.04.018_bib23","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jcv.2009.07.014","article-title":"Varicella-zoster virus CNS disease-viral load, clinical manifestations and sequels","volume":"46","author":"Persson","year":"2009","journal-title":"J Clin Virol"}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846710001356?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846710001356?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:27:49Z","timestamp":1759588069000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846710001356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S0303846710001356"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2010.04.018","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Varicella zoster virus in progressive forms of multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurology and Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clineuro.2010.04.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}