{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:16:04Z","timestamp":1783390564703,"version":"3.54.6"},"reference-count":32,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.clineuro.2011.05.002","type":"journal-article","created":{"date-parts":[[2011,6,26]],"date-time":"2011-06-26T00:52:53Z","timestamp":1309049573000},"page":"570-574","source":"Crossref","is-referenced-by-count":25,"title":["Neurologic symptoms and diagnosis in adults with mast cell disease"],"prefix":"10.1016","volume":"113","author":[{"given":"Jonathan H.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph H.","family":"Butterfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Animesh","family":"Pardanani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele C.","family":"DeLuca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Michael","family":"Cutrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clineuro.2011.05.002_bib0005","first-page":"185","article-title":"Regulation of normal and neoplastic human mast cell development in mastocytosis","volume":"116","author":"Metcalfe","year":"2005","journal-title":"Trans Am Clin Climatol Assoc"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0010","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000048188","article-title":"Mastocytosis: mediator-related signs and symptoms","volume":"127","author":"Castells","year":"2002","journal-title":"Int Arch Allergy Immunol"},{"issue":"6","key":"10.1016\/j.clineuro.2011.05.002_bib0015","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00006842-198607000-00006","article-title":"Mixed organic brain syndrome as a manifestation of systemic mastocytosis","volume":"48","author":"Rogers","year":"1986","journal-title":"Psychosom Med"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0020","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1136\/jnnp.51.11.1457-a","article-title":"Chorea: A new manifestation of mastocytosis","volume":"51","author":"Iriarte","year":"1988","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2169\/internalmedicine.33.23","article-title":"Sequential magnetic resonance features of encephalopathy induced by systemic mastocytosis","volume":"33","author":"Tajima","year":"1994","journal-title":"Intern Med"},{"issue":"5","key":"10.1016\/j.clineuro.2011.05.002_bib0030","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s002770000271","article-title":"Complex karyotype and absence of mutation in the c-kit receptor in aggressive mastocytosis presenting with pelvic osteolysis, eosinophilia, and brain damage","volume":"80","author":"Jost","year":"2001","journal-title":"Ann Hematol"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0035","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1212\/01.wnl.0000168897.35545.61","article-title":"Systemic mastocytosis: A potential neurologic emergency","volume":"65","author":"Boncoraglio","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0040","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0303-8467(92)90100-H","article-title":"Generalized mastocytosis and neurological complications in a 71-year-old patient","volume":"94","author":"Frijns","year":"1992","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0045","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1136\/pgmj.52.612.659","article-title":"Systemic mastocytosis \u2013 central nervous system features and lymphographic demonstration of lymph node involvement","volume":"52","author":"Hancock","year":"1976","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0050","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00005792-198811000-00001","article-title":"Systemic mast cell disease. Analysis of 58 cases and review of the literature","volume":"67","author":"Travis","year":"1988","journal-title":"Medicine"},{"issue":"5","key":"10.1016\/j.clineuro.2011.05.002_bib0055","doi-asserted-by":"crossref","first-page":"e2266","DOI":"10.1371\/journal.pone.0002266","article-title":"Case-control cohort study of patients\u2019 perceptions of disability in mastocytosis","volume":"3","author":"Hermine","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0060","series-title":"WHO classification of tumors of hematopoietic and lymphoid tissues","first-page":"54","article-title":"Mastocytosis","author":"Horny","year":"2008"},{"issue":"Suppl. 1","key":"10.1016\/j.clineuro.2011.05.002_bib0065","first-page":"9","article-title":"The international classification of headache disorders: 2nd edition","volume":"24","author":"Headache Classification Subcommittee of the International Headache Society","year":"2004","journal-title":"Cephalalgia"},{"issue":"6","key":"10.1016\/j.clineuro.2011.05.002_bib0070","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/ana.20703","article-title":"Diagnostic criteria for multiple sclerosis: 2005 revisions to the \u201cMcDonald Criteria\u201d","volume":"58","author":"Polman","year":"2005","journal-title":"Ann Neurol"},{"issue":"11","key":"10.1016\/j.clineuro.2011.05.002_bib0075","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1002\/jbmr.5650051104","article-title":"Inhibition of mediator release in systemic mastocytosis is associated with reversal of bone changes","volume":"5","author":"Graves","year":"1990","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0080","doi-asserted-by":"crossref","DOI":"10.1136\/ard.2009.124511","article-title":"Systemic mastocytosis and bone involvement in a cohort of 75 patients","author":"Barete","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0085","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1468-2982.2004.00852.x","article-title":"Headache in systemic mastocytosis: a case report with pathophysiological considerations","volume":"25","author":"Ashina","year":"2004","journal-title":"Cephalalgia"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0090","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.brainresrev.2004.11.006","article-title":"The role of mast cells in Migraine pathophysiology","volume":"49","author":"Theoharides","year":"2005","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0095","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1124\/jpet.107.123745","article-title":"Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators","volume":"322","author":"Zhang","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0100","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.pain.2007.03.012","article-title":"Mast cell degranulation activates a pain pathway underlying migraine headache","volume":"130","author":"Levy","year":"2007","journal-title":"Pain"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0105","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.0333-1024.2001.00204.x","article-title":"Low-dose aspirin for migraine prophylaxis in women","volume":"21","author":"Diener","year":"2001","journal-title":"Cephalalgia"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0110","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1526-4610.1993.hed3310541.x","article-title":"Intravenous acetylsalicylic acid inhibits central trigeminal neurons in the dorsal horn of the upper cervical spinal cord in the cat","volume":"33","author":"Kaube","year":"1993","journal-title":"Headache"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0115","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1042\/CS20010179","article-title":"Prostaglandin F2a metabolite and F2-isoprostane excretion rates in migraine","volume":"102","author":"Helmersson","year":"2002","journal-title":"Clin Sci"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0120","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/j.1526-4610.1989.hed2908498.x","article-title":"Increase in PGE2 and TXA2 in the saliva of common migraine patients. Action of calcium channel blockers","volume":"29","author":"Tuca","year":"1989","journal-title":"Headache"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0125","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1212\/01.WNL.0000094316.90240.EB","article-title":"Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985\u20132000","volume":"61","author":"Mayr","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0130","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jneuroim.2008.01.017","article-title":"Mast cell transcripts are increased within and outside multiple sclerosis lesions","volume":"195","author":"Couturerier","year":"2008","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0135","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0165-5728(96)00102-6","article-title":"The mast cells of the multiple sclerosis brain","volume":"70","author":"Ibrahim","year":"1996","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0140","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.0305-1846.2001.00331.x","article-title":"Mast cells and multiple sclerosis: a quantitative analysis","volume":"27","author":"Kruger","year":"2001","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0145","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/ana.410370112","article-title":"Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients","volume":"37","author":"Rozniecki","year":"1995","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0150","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0165-5728(90)90101-R","article-title":"Identification of IgE-positive cells and mast cells in frozen sections of multiple sclerosis brains","volume":"30","author":"Toms","year":"1990","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.clineuro.2011.05.002_bib0155","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/00005072-199105000-00005","article-title":"An analysis of mast cell frequency in the rodent nervous system: Numbers vary between different strains and can be reconstituted in mast cell-deficient mice","volume":"50","author":"Johnson","year":"1991","journal-title":"J Neuropathol Exp Neurol"},{"issue":"5","key":"10.1016\/j.clineuro.2011.05.002_bib0160","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1084\/jem.191.5.813","article-title":"Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis","volume":"191","author":"Secor","year":"2000","journal-title":"J Exp Med"}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846711001351?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846711001351?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T23:20:42Z","timestamp":1543706442000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846711001351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0303846711001351"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2011.05.002","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}