{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:10:37Z","timestamp":1780103437240,"version":"3.54.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.clineuro.2012.06.013","type":"journal-article","created":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T16:28:25Z","timestamp":1341592105000},"page":"432-437","source":"Crossref","is-referenced-by-count":16,"title":["The predictive value of the presence of different antibodies and thymus pathology to the clinical outcome in patients with generalized myasthenia gravis"],"prefix":"10.1016","volume":"115","author":[{"given":"A.","family":"Nikolic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Djukic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Basta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lj.","family":"Hajdukovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. Rakocevic","family":"Stojanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Stevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Nikolic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bozic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Lavrnic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Lavrnic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clineuro.2012.06.013_bib0005","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/(SICI)1097-4598(200004)23:4<453::AID-MUS3>3.0.CO;2-O","article-title":"Acetylcholine receptors and myasthenia gravis","volume":"23","author":"Lindstrom","year":"2000","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0010","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1111\/j.1749-6632.1987.tb51321.x","article-title":"Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis","volume":"505","author":"Howard","year":"1987","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0015","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1136\/jnnp.48.12.1246","article-title":"Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays","volume":"48","author":"Vincent","year":"1985","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0020","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1056\/NEJM198209233071301","article-title":"Functional activities of autoantibodies to acetylcholine receptors and the clinical severity of myasthenia gravis","volume":"307","author":"Drachman","year":"1982","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0025","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1093\/brain\/awg223","article-title":"Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis","volume":"126","author":"Evoli","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0030","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1212\/01.WNL.0000065882.63904.53","article-title":"Clinical aspects of MuSK antibody positive seronegative MG","volume":"60","author":"Sanders","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0035","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1136\/jnnp.2004.052415","article-title":"The features of myasthenia gravis with autoantibodies to MuSK","volume":"76","author":"Lavrnic","year":"2005","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0040","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1172\/JCI21545","article-title":"Induction of myasthenia by immunization against muscle-specific kinase","volume":"116","author":"Shigemoto","year":"2006","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0045","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1083\/jcb.200307164","article-title":"MuSK is required for anchoring acetylcholinesterase at the neuromuscular junction","volume":"165","author":"Cartaud","year":"2004","journal-title":"Journal of Cell Biology"},{"issue":"7","key":"10.1016\/j.clineuro.2012.06.013_bib0050","first-page":"695","article-title":"Myasthenia gravis with anti-acetylcholine receptor antibody or anti-muscle specific kinase antibody","volume":"63","author":"Konishi","year":"2011","journal-title":"Brain and Nerve"},{"issue":"10","key":"10.1016\/j.clineuro.2012.06.013_bib0055","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1136\/jnnp.2006.109488","article-title":"Myasthenia gravis: a long term follow-up study of Swedish patients with specific reference to thymic histology","volume":"78","author":"Tsinzerling","year":"2007","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0060","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1212\/WNL.55.1.16","article-title":"Myasthenia gravis: recommendations for clinical research standards. Task force of the Medical Scientific Advisory Board of the Myasthenia gravis Foundation of America","volume":"55","author":"Jeretzki","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0065","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/mus.20069","article-title":"Clinical comparison of muscle-specific tyrosine kinase (MuSK) antibody-positive and -negative myasthenic patients","volume":"30","author":"Zhou","year":"2004","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0070","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/85520","article-title":"Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies","volume":"7","author":"Hoch","year":"2001","journal-title":"Nature Medicine"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0075","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s004280050044","article-title":"Pathogenesis of myasthenia gravis","volume":"430","author":"Marx","year":"1997","journal-title":"Virchows Archiv"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0080","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/nri916","article-title":"Unravelling the pathogenesis of myasthenia gravis","volume":"2","author":"Vincent","year":"2002","journal-title":"Nature Reviews Immunology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0085","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.1468-1331.2006.01476.x","article-title":"Guidelines for the treatment of autoimmune neuromuscular transmission disorders","volume":"13","author":"Skeie","year":"2006","journal-title":"European Journal of Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0090","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/jnnp.2007.134130","article-title":"When the patient fails to respond to treatment: myasthenia gravis","volume":"7","author":"Hilton-Jones","year":"2007","journal-title":"Practical Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0095","first-page":"56","article-title":"Immunopathology of the human thymus","volume":"22","author":"Tridente","year":"1985","journal-title":"Seminars in Hematology"},{"issue":"25","key":"10.1016\/j.clineuro.2012.06.013_bib0100","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1056\/NEJM199406233302507","article-title":"Medical progress: myasthenia gravis","volume":"330","author":"Drachman","year":"1994","journal-title":"The New England Journal of Medicine"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0105","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1620\/tjem.169.77","article-title":"Treatment of myasthenia gravis: a comparison of the natural course and current therapies","volume":"169","author":"Seto","year":"1993","journal-title":"Tohoku Journal of Experimental Medicine"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0110","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1212\/WNL.34.1.66","article-title":"Anti-AChR antibodies, thymic histology and T cell subsets in myasthenia gravis","volume":"34","author":"Berrih","year":"1984","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0115","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1212\/01.WNL.0000150587.71497.B6","article-title":"Thymus changes in anti-MuSK-positive and -negative myasthenia gravis","volume":"64","author":"Lauriola","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0120","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/BF00319736","article-title":"The thymus in seronegative myasthenia gravis patients","volume":"238","author":"Willcox","year":"1991","journal-title":"Journal of Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0125","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1212\/WNL.42.3.586","article-title":"Seronegative generalized myasthenia gravis: low frequency of thymic pathology","volume":"42","author":"Verma","year":"1992","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0130","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/j.1749-6632.1993.tb22936.x","article-title":"Seronegative myasthenia gravis. Evidence for plasma factor(s) interfering with acetylcholine receptor function","volume":"681","author":"Vincent","year":"1993","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0135","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/mus.22006","article-title":"Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts","volume":"44","author":"Guptill","year":"2011","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.clineuro.2012.06.013_bib0140","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1034\/j.1600-0404.2003.00209.x","article-title":"Response of thymectomy: clinical and pathological characteristics among seronegative and seropositive myasthenia gravis patients","volume":"109","author":"Guillermo","year":"2004","journal-title":"Acta Neurologica Scandinavica"},{"issue":"8","key":"10.1016\/j.clineuro.2012.06.013_bib0145","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1212\/01.wnl.0000254620.45529.97","article-title":"Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis","volume":"68","author":"Deymeer","year":"2007","journal-title":"Neurology"}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846712003320?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846712003320?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T04:01:16Z","timestamp":1687579276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846712003320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0303846712003320"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2012.06.013","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}