{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T17:48:58Z","timestamp":1759600138096,"version":"3.40.5"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.clineuro.2018.01.001","type":"journal-article","created":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T13:10:42Z","timestamp":1514898642000},"page":"55-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Can vascular risk factors influence number and size of cerebral metastases? A 3D-MRI study in patients with different tumor entities"],"prefix":"10.1016","volume":"165","author":[{"given":"Sandra","family":"Nagel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin-Andreas","family":"Berk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf-Dieter","family":"Kortmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl-Titus","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8178-5089","authenticated-orcid":false,"given":"Clemens","family":"Seidel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.clineuro.2018.01.001_bib0005","doi-asserted-by":"crossref","DOI":"10.1007\/s00415-002-0870-6","article-title":"Management of brain metastases","volume":"249","author":"Soffietti","year":"2002","journal-title":"J. Neurol."},{"issue":"4","key":"10.1016\/j.clineuro.2018.01.001_bib0010","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2011.38.0527","article-title":"Summary report on the graded prognostic assessment: an accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases","volume":"30","author":"Sperduto","year":"2011","journal-title":"J. Clin. Oncol."},{"issue":"6","key":"10.1016\/j.clineuro.2018.01.001_bib0015","first-page":"CD006121","article-title":"Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases","author":"Patil","year":"2010","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.clineuro.2018.01.001_bib0020","first-page":"952345","article-title":"The role of surgery, radiosurgery and whole brain radiation therapy in the management of patients with metastatic brain tumors","author":"Ellis","year":"2012","journal-title":"Int. J. Surg. Oncol."},{"issue":"6","key":"10.1016\/j.clineuro.2018.01.001_bib0025","doi-asserted-by":"crossref","first-page":"e5857","DOI":"10.1371\/journal.pone.0005857","article-title":"The vascular basement membrane as \u201csoil\u201d in brain metastasis","volume":"4","author":"Carbonell","year":"2009","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.clineuro.2018.01.001_bib0030","doi-asserted-by":"crossref","DOI":"10.1001\/archneur.1988.00520310047016","article-title":"Distribution of brain metastases","volume":"45","author":"Delattre","year":"1988","journal-title":"Arch. Neurol."},{"issue":"1","key":"10.1016\/j.clineuro.2018.01.001_bib0035","doi-asserted-by":"crossref","DOI":"10.1007\/s11060-015-1773-6","article-title":"Analysis of frequency of deep white matter metastasis on cerebral MRI","volume":"123","author":"Seidel","year":"2015","journal-title":"J. Neurooncol."},{"issue":"6 Pt. 2","key":"10.1016\/j.clineuro.2018.01.001_bib0040","article-title":"Interdependency of local capillary density, blood flow, and metabolism in rat brains","volume":"251","author":"Klein","year":"1986","journal-title":"Am. J. Physiol."},{"issue":"8","key":"10.1016\/j.clineuro.2018.01.001_bib0045","article-title":"Age-related total gray matter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis","volume":"23","author":"Ge","year":"2002","journal-title":"Am. J. Neuroradiol."},{"issue":"9","key":"10.1016\/j.clineuro.2018.01.001_bib0050","doi-asserted-by":"crossref","first-page":"e7242","DOI":"10.1371\/journal.pone.0007242","article-title":"Small vessel ischemic disease of the brain and brain metastases in lung cancer patients","volume":"4","author":"Mazzone","year":"2009","journal-title":"PLoS One"},{"issue":"Jul","key":"10.1016\/j.clineuro.2018.01.001_bib0055","article-title":"Negative impact of leukoaraiosis on the incidence of brain metastases in patients with lung cancer","volume":"27","author":"Hayashi","year":"2017","journal-title":"J. Neurooncol."},{"issue":"1","key":"10.1016\/j.clineuro.2018.01.001_bib0060","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s11060-016-2235-5","article-title":"White matter lesions reduce number of brain metastases in different cancers - a high-resolution MRI study","volume":"130","author":"Berk","year":"2016","journal-title":"J. Neurooncol."},{"issue":"2","key":"10.1016\/j.clineuro.2018.01.001_bib0065","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2214\/ajr.149.2.351","article-title":"MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging","volume":"149","author":"Fazekas","year":"1987","journal-title":"AJR Am. J. Roentgenol."},{"year":"2016","series-title":"Kolmogorov-Smirnov-Test With SPSS","author":"Ebermann","key":"10.1016\/j.clineuro.2018.01.001_bib0070"},{"issue":"4","key":"10.1016\/j.clineuro.2018.01.001_bib0075","doi-asserted-by":"crossref","DOI":"10.1007\/s00520-015-2928-x","article-title":"The relationship between smoking and quality of life in advanced lung cancer patients: a prospective longitudinal study","volume":"24","author":"Danson","year":"2016","journal-title":"Support Care Cancer"},{"issue":"1","key":"10.1016\/j.clineuro.2018.01.001_bib0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2016.02.006","article-title":"Diabetes and cancer, common threads and missing links","volume":"374","author":"Hua","year":"2016","journal-title":"Cancer Lett."},{"issue":"14","key":"10.1016\/j.clineuro.2018.01.001_bib0085","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.ehj.2004.03.011","article-title":"Atherothrombosis: a widespread disease with unpredictable and life-threatening consequences","volume":"25","author":"Viles-Gonzalez","year":"2004","journal-title":"Eur. Heart J."},{"year":"2014","series-title":"Cerebral Small Vessel Disease","author":"Pantoni","key":"10.1016\/j.clineuro.2018.01.001_bib0090"},{"key":"10.1016\/j.clineuro.2018.01.001_bib0095","doi-asserted-by":"crossref","first-page":"6423","DOI":"10.1038\/362801a0","article-title":"The pathogenesis of atherosclerosis: a perspective for the 1990s","volume":"362","author":"Ross","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.clineuro.2018.01.001_bib0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjmed.2008.10.013","article-title":"The pathology of atherosclerosis: plaque development and plaque responses to medical treatment","volume":"122","author":"Insull","year":"2009","journal-title":"Am. J. Med."},{"issue":"3","key":"10.1016\/j.clineuro.2018.01.001_bib0105","article-title":"The pathogenesis of hyaline arteriolosclerosis","volume":"122","author":"CN","year":"1986","journal-title":"Am. J. Pathol."},{"issue":"16","key":"10.1016\/j.clineuro.2018.01.001_bib0110","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1001\/jama.2012.13415","article-title":"Associations between conventional cardiovascular risk factors and risk of peripheral artery disease in men","volume":"308","author":"Joosten","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.clineuro.2018.01.001_bib0115","first-page":"9901","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis","volume":"382","author":"Fowkes","year":"2012","journal-title":"Lancet"},{"issue":"31","key":"10.1016\/j.clineuro.2018.01.001_bib0120","doi-asserted-by":"crossref","first-page":"5278","DOI":"10.1200\/JCO.2008.19.8481","article-title":"Human epidermal growth factor receptor 2-positive breast cancer and central nervous system metastases","volume":"27","author":"Leyland-Jones","year":"2009","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.clineuro.2018.01.001_bib0125","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1183\/09031936.00195609","article-title":"Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation","volume":"37","author":"Porta","year":"2011","journal-title":"Eur. Respir. J."},{"issue":"5","key":"10.1016\/j.clineuro.2018.01.001_bib0130","doi-asserted-by":"crossref","DOI":"10.1093\/neuonc\/nov266","article-title":"Different spatial distributions of brain metastases from lung cancer by histological subtype and mutation status of epidermal growth factor receptor","volume":"18","author":"Takano","year":"2016","journal-title":"Neuro Oncol."}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846718300015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846718300015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T19:12:03Z","timestamp":1570561923000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846718300015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":26,"alternative-id":["S0303846718300015"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2018.01.001","relation":{},"ISSN":["0303-8467"],"issn-type":[{"type":"print","value":"0303-8467"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Can vascular risk factors influence number and size of cerebral metastases? A 3D-MRI study in patients with different tumor entities","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurology and Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clineuro.2018.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}