{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:25:44Z","timestamp":1792589144087,"version":"4.5.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.clineuro.2019.105480","type":"journal-article","created":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T10:43:29Z","timestamp":1565433809000},"page":"105480","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Spinal epidural lipomatosis is associated with liver fat deposition and dysfunction"],"prefix":"10.1016","volume":"185","author":[{"given":"Tetsutaro","family":"Abe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshinobu","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shozo","family":"Kanezaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Notani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Tsumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clineuro.2019.105480_bib0005","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.spinee.2016.06.022","article-title":"Patient-reported outcome of surgical treatment for lumbar spinal epidural lipomatosis","volume":"16","author":"Ferlic","year":"2016","journal-title":"Spine J."},{"key":"10.1016\/j.clineuro.2019.105480_bib0010","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.spinee.2004.05.252","article-title":"Spinal epidural lipomatosis: case reports, literature review and meta-analysis","volume":"5","author":"Fogel","year":"2005","journal-title":"Spine J."},{"key":"10.1016\/j.clineuro.2019.105480_bib0015","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1097\/00006123-199707000-00015","article-title":"Idiopathic spinal epidural lipomatosis","volume":"41","author":"Robertson","year":"1997","journal-title":"Neurosurgery"},{"key":"10.1016\/j.clineuro.2019.105480_bib0020","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.spinee.2017.02.010","article-title":"The prevalence of spinal epidural lipomatosis on magnetic resonance imaging","volume":"17","author":"Theyskens","year":"2017","journal-title":"Spine J."},{"key":"10.1016\/j.clineuro.2019.105480_bib0025","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/865965","article-title":"Obesity-related metabolic syndrome: mechanisms of sympathetic overactivity","volume":"2013","author":"Canale","year":"2013","journal-title":"Int. J. Endocrinol."},{"key":"10.1016\/j.clineuro.2019.105480_bib0030","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1089\/met.2013.0107","article-title":"The relationship between epicardial fat and indices of obesity and the metabolic syndrome: a systematic review and meta-analysis","volume":"12","author":"Rabkin","year":"2014","journal-title":"Metab. Syndr. Relat. Disord."},{"key":"10.1016\/j.clineuro.2019.105480_bib0035","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s11154-014-9294-8","article-title":"Metabolic syndrome and lifestyle modification","volume":"15","author":"Takahara","year":"2014","journal-title":"Rev. Endocr. Metab. Disord."},{"issue":"742","key":"10.1016\/j.clineuro.2019.105480_bib0040","article-title":"An unusual complication of morbid obesity: epidural lipomatosis","volume":"33","author":"Noh","year":"2015","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.clineuro.2019.105480_bib0045","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S2213-8587(14)70032-4","article-title":"Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome","volume":"2","author":"Yki-Jarvinen","year":"2014","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.clineuro.2019.105480_bib0050","doi-asserted-by":"crossref","first-page":"623","DOI":"10.2214\/AJR.09.2590","article-title":"Hepatic steatosis (fatty liver disease) in asymptomatic adults identified by unenhanced low-dose CT","volume":"194","author":"Boyce","year":"2010","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.clineuro.2019.105480_bib0055","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1007\/s00330-002-1716-4","article-title":"Lumbosacral epidural lipomatosis: MRI grading","volume":"13","author":"Borre","year":"2003","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.clineuro.2019.105480_bib0060","doi-asserted-by":"crossref","first-page":"201","DOI":"10.5694\/j.1326-5377.1975.tb111328.x","article-title":"Spinal cord compression by extradural fat after renal transplantation","volume":"1","author":"Lee","year":"1975","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.clineuro.2019.105480_bib0065","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3171\/spi.2006.4.1.24","article-title":"Decompression of idiopathic lumbar epidural lipomatosis: diagnostic magnetic resonance imaging evaluation and review of the literature","volume":"4","author":"Shimada","year":"2006","journal-title":"J. Neurosurg. Spine"},{"key":"10.1016\/j.clineuro.2019.105480_bib0070","doi-asserted-by":"crossref","first-page":"348","DOI":"10.3171\/jns.1996.85.2.0348","article-title":"Symptomatic epidural lipomatosis secondary to obesity. Case report","volume":"85","author":"Kumar","year":"1996","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.clineuro.2019.105480_bib0075","first-page":"e362","article-title":"Spinal epidural lipomatosis in lumbar magnetic resonance imaging scans","volume":"37","author":"Mishima","year":"2014","journal-title":"Orthopedics"},{"key":"10.1016\/j.clineuro.2019.105480_bib0080","doi-asserted-by":"crossref","first-page":"E1402","DOI":"10.1097\/BRS.0000000000001646","article-title":"Potential involvement of obesity-associated chronic inflammation in the pathogenesis of idiopathic spinal epidural lipomatosis","volume":"41","author":"Hosogane","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.clineuro.2019.105480_bib0085","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1007\/s00586-018-5584-2","article-title":"Lumbar epidural lipomatosis is associated with visceral fat and metabolic disorders","volume":"27","author":"Morishita","year":"2018","journal-title":"Eur. Spine J."},{"key":"10.1016\/j.clineuro.2019.105480_bib0090","doi-asserted-by":"crossref","first-page":"629","DOI":"10.5551\/jat.7922","article-title":"The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism","volume":"18","author":"Matsuzawa","year":"2011","journal-title":"J. Atheroscler. Thromb."},{"key":"10.1016\/j.clineuro.2019.105480_bib0095","first-page":"249","article-title":"Adipose tissue volume determination in males by computed tomography and 40K","volume":"12","author":"Kvist","year":"1988","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.clineuro.2019.105480_bib0100","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s10522-017-9693-9","article-title":"Associations of visceral fat area and physical activity levels with the risk of metabolic syndrome in postmenopausal women","volume":"18","author":"Zajac-Gawlak","year":"2017","journal-title":"Biogerontology"},{"key":"10.1016\/j.clineuro.2019.105480_bib0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2152\/jmi.60.1","article-title":"Ectopic fat deposition and global cardiometabolic risk: new paradigm in cardiovascular medicine","volume":"60","author":"Shimabukuro","year":"2013","journal-title":"J. Med. Invest."},{"key":"10.1016\/j.clineuro.2019.105480_bib0110","doi-asserted-by":"crossref","first-page":"814","DOI":"10.5551\/jat.12294","article-title":"Impact of visceral adipose tissue and subcutaneous adipose tissue on insulin resistance in middle-aged Japanese","volume":"19","author":"Oka","year":"2012","journal-title":"J. Atheroscler. Thromb."}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846719302768?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846719302768?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:30:00Z","timestamp":1759588200000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846719302768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":22,"alternative-id":["S0303846719302768"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2019.105480","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spinal epidural lipomatosis is associated with liver fat deposition and dysfunction","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurology and Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clineuro.2019.105480","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105480"}}