{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:42:53Z","timestamp":1778931773249,"version":"3.51.4"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"China National Key R&D Program during the 13th Five-year Plan Period","award":["2015BAI12B04"],"award-info":[{"award-number":["2015BAI12B04"]}]},{"name":"Beijing Hospital Clinical Research 121 Program","award":["121-2016006"],"award-info":[{"award-number":["121-2016006"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.clineuro.2019.105543","type":"journal-article","created":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T11:24:36Z","timestamp":1569929076000},"page":"105543","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Relationship between cerebrovascular atherosclerotic stenosis and rupture risk of unruptured intracranial aneurysm: A single-center retrospective study"],"prefix":"10.1016","volume":"186","author":[{"given":"Xin","family":"Feng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai Feng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shen","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7298-2571","authenticated-orcid":false,"given":"Daming","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clineuro.2019.105543_bib0005","first-page":"887","article-title":"Endovascular treatment of intracranial unruptured aneurysms: systematic review and meta-analysis of the literature on safety and efficacy","volume":"256","author":"Naggara","year":"2010","journal-title":"Int. J. Med. Radiol."},{"issue":"1","key":"10.1016\/j.clineuro.2019.105543_bib0010","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1136\/jnnp-2011-302068","article-title":"Safety and occlusion rates of surgical treatment of unruptured intracranial aneurysms: a systematic review and meta-analysis of the literature from 1990 to 2011","volume":"84","author":"Kotowski","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatr."},{"issue":"2","key":"10.1016\/j.clineuro.2019.105543_bib0015","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/nrneurol.2017.14","article-title":"Unruptured intracranial aneurysms: development, rupture and preventive management","volume":"13","author":"Etminan","year":"2016","journal-title":"Nat. Rev. Neurol."},{"issue":"1","key":"10.1016\/j.clineuro.2019.105543_bib0020","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1161\/01.STR.29.1.251","article-title":"Prevalence and risk of rupture of intracranial aneurysms\u202f: a systematic review","volume":"29","author":"Rinkel","year":"1998","journal-title":"Stroke"},{"issue":"9","key":"10.1016\/j.clineuro.2019.105543_bib0025","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1038\/jcbfm.2012.84","article-title":"Biology of intracranial aneurysms: role of inflammation","volume":"32","author":"Chalouhi","year":"2012","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"5","key":"10.1016\/j.clineuro.2019.105543_bib0030","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1161\/ATVBAHA.110.207415","article-title":"Recent advances on the role of cytokines in atherosclerosis","volume":"31","author":"Aitoufella","year":"2011","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"9","key":"10.1016\/j.clineuro.2019.105543_bib0035","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.04.019","article-title":"The impact of atherosclerotic factors on cerebral aneurysm is location dependent: aneurysms in stroke patients and healthy controls","volume":"23","author":"Hokari","year":"2014","journal-title":"J. Stroke Cerebrovasc. Dis."},{"issue":"6","key":"10.1016\/j.clineuro.2019.105543_bib0040","first-page":"271582","article-title":"Cigarette smoke and inflammation: role in cerebral aneurysm formation and rupture","author":"Chalouhi","year":"2012","journal-title":"Mediators Inflamm."},{"issue":"4","key":"10.1016\/j.clineuro.2019.105543_bib0045","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.carpath.2011.09.010","article-title":"Histological analysis of clipped human intracranial aneurysms and parent arteries with short-term follow-up","volume":"21","author":"Killeroberpfalzer","year":"2012","journal-title":"Cardiovasc. Pathol."},{"issue":"4","key":"10.1016\/j.clineuro.2019.105543_bib0050","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00005072-199407000-00012","article-title":"Immunocytochemical studies of atherosclerotic lesions of cerebral berry aneurysms","volume":"53","author":"Kosierkiewicz","year":"1994","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"1","key":"10.1016\/j.clineuro.2019.105543_bib0055","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.atherosclerosis.2010.05.012","article-title":"In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate","volume":"212","author":"Sheth","year":"2010","journal-title":"Atherosclerosis"},{"issue":"1","key":"10.1016\/j.clineuro.2019.105543_bib0060","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.yrtph.2014.07.009","article-title":"Evaluating the association between menthol cigarette use and the likelihood of being a former versus current smoker","volume":"70","author":"Sulsky","year":"2014","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.clineuro.2019.105543_bib0065","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0140-6736(03)12228-3","article-title":"Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis","volume":"361","author":"Rothwell","year":"2003","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.clineuro.2019.105543_bib0070","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1212\/WNL.45.8.1488","article-title":"The warfarin-aspirin symptomatic intracranial disease study","volume":"45","author":"Chimowitz","year":"1995","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.clineuro.2019.105543_bib0075","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/cvr\/cvy007","article-title":"Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis","volume":"114","author":"Grootaert","year":"2018","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.clineuro.2019.105543_bib0080","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.atherosclerosis.2017.11.007","article-title":"Lipoprotein-associated phospholipase a 2, and risk of incident peripheral arterial disease: findings from the atherosclerosis risk in communities study (aric)","volume":"268","author":"Garg","year":"2018","journal-title":"Atherosclerosis"},{"issue":"2","key":"10.1016\/j.clineuro.2019.105543_bib0085","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.yexmp.2018.01.008","article-title":"Potential of anti-inflammatory agents for treatment of atherosclerosis","volume":"104","author":"Chistiakov","year":"2018","journal-title":"Exp. Mol. Pathol."},{"issue":"4","key":"10.1016\/j.clineuro.2019.105543_bib0090","first-page":"1","article-title":"Association between hemodynamics, morphology, and rupture risk of intracranial aneurysms: a computational fluid modeling study","volume":"38","author":"Qiu","year":"2017","journal-title":"Neurol. Sci."},{"issue":"1","key":"10.1016\/j.clineuro.2019.105543_bib0095","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1083\/jcb.201412052","article-title":"Recent insights into the cellular biology of atherosclerosis","volume":"209","author":"Tabas","year":"2015","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.clineuro.2019.105543_bib0100","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.yexmp.2018.01.008","article-title":"Potential of anti-inflammatory agents for treatment of atherosclerosis","volume":"104","author":"Chistiakov","year":"2018","journal-title":"Exp. Mol. Pathol."},{"issue":"5","key":"10.1016\/j.clineuro.2019.105543_bib0105","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1093\/neuros\/nyx267","article-title":"Circumferential wall enhancement on magnetic resonance imaging is useful to identify rupture site in patients with multiple cerebral aneurysms","volume":"82","author":"Omodaka","year":"2017","journal-title":"Neurosurgery"},{"key":"10.1016\/j.clineuro.2019.105543_bib0110","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1161\/STROKEAHA.118.021819","article-title":"Clinicopathological insights from vessel wall imaging of unruptured intracranial aneurysms","volume":"49","author":"Shimonaga","year":"2018","journal-title":"Stroke"},{"key":"10.1016\/j.clineuro.2019.105543_bib0115","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1161\/STROKEAHA.118.021819","article-title":"Clinicopathological insights from vessel wall imaging of unruptured intracranial aneurysms","volume":"49","author":"Shimonaga","year":"2018","journal-title":"Stroke"},{"issue":"12","key":"10.1016\/j.clineuro.2019.105543_bib0120","first-page":"e1175","article-title":"Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms","volume":"91","author":"Anil","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.clineuro.2019.105543_bib0125","doi-asserted-by":"crossref","first-page":"3156","DOI":"10.1161\/STROKEAHA.111.619411","article-title":"Aspirin as a promising agent for decreasing incidence of cerebral aneurysm rupture","volume":"42","author":"Hasan","year":"2011","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.clineuro.2019.105543_bib0130","doi-asserted-by":"crossref","DOI":"10.1136\/neurintsurg-2014-011471","article-title":"Interobserver variability of aneurysm morphology: discrimination of the daughter sac","volume":"8","author":"Suh","year":"2016","journal-title":"J. Neurointerv. Surg."}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846719303397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846719303397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:31:54Z","timestamp":1759588314000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846719303397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":26,"alternative-id":["S0303846719303397"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2019.105543","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between cerebrovascular atherosclerotic stenosis and rupture risk of unruptured intracranial aneurysm: A single-center retrospective study","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurology and Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clineuro.2019.105543","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105543"}}