{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:49:40Z","timestamp":1792176580772,"version":"4.4.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.clineuro.2020.106397","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T02:02:03Z","timestamp":1607133723000},"page":"106397","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Molecular mechanisms of trigeminal neuralgia: A systematic review"],"prefix":"10.1016","volume":"200","author":[{"given":"Cynthia A.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Paskhover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonios","family":"Mammis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.clineuro.2020.106397_bib0005","first-page":"91","article-title":"Pathological mechanisms and therapeutic targets for trigeminal neuropathic pain","volume":"6","author":"Bista","year":"2019","journal-title":"Med. Basel"},{"issue":"10","key":"10.1016\/j.clineuro.2020.106397_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11916-019-0810-0","article-title":"A comprehensive review of trigeminal neuralgia","volume":"23","author":"Jones","year":"2019","journal-title":"Curr. Pain Headache Rep."},{"key":"10.1016\/j.clineuro.2020.106397_bib0015","doi-asserted-by":"crossref","DOI":"10.1177\/1744806920901890","article-title":"Trigeminal neuralgia: an overview from pathophysiology to pharmacological treatments","volume":"16","author":"Gambeta","year":"2020","journal-title":"Mol. Pain"},{"issue":"9","key":"10.1016\/j.clineuro.2020.106397_bib0020","first-page":"1291","article-title":"Trigeminal neuralgia","volume":"77","author":"Krafft","year":"2008","journal-title":"Am. Fam. Phys."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0025","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1177\/204946371100500105","article-title":"Trigeminal neuralgia - a debilitating facial pain","volume":"5","author":"McMillan","year":"2011","journal-title":"Rev. Pain"},{"issue":"9","key":"10.1016\/j.clineuro.2020.106397_bib0030","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1212\/WNL.22.9.952","article-title":"Tic douloureux in Rochester, Minnesota, 1945-1969","volume":"22","author":"Yoshimasu","year":"1972","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0035","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/ana.410270114","article-title":"Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945-1984","volume":"27","author":"Katusic","year":"1990","journal-title":"Ann. Neurol."},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0040","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1177\/1756285609359317","article-title":"Treatment options in trigeminal neuralgia","volume":"3","author":"Obermann","year":"2010","journal-title":"Ther. Adv. Neurol. Disord."},{"issue":"4","key":"10.1016\/j.clineuro.2020.106397_bib0045","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.nrleng.2016.12.003","article-title":"Familial classic trigeminal neuralgia","volume":"34","author":"Fern\u00e1ndez Rodr\u00edguez","year":"2019","journal-title":"Neurolog\u00eda (English Edition)."},{"key":"10.1016\/j.clineuro.2020.106397_bib0050","article-title":"Familial trigeminal neuralgia - a systematic clinical study with a genomic screen of the neuronal electrogenisome [published online ahead of print, 2020 Jan 13]","author":"Di Stefano","year":"2020","journal-title":"Cephalalgia"},{"issue":"3","key":"10.1016\/j.clineuro.2020.106397_bib0055","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3171\/jns.2001.95.3.0513","article-title":"Familial trigeminal neuralgia. Case report and review of the literature","volume":"95","author":"Fleetwood","year":"2001","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.clineuro.2020.106397_bib0060","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3389\/fneur.2018.00316","article-title":"Surgical management of familial trigeminal neuralgia with different inheritance patterns: a case report","volume":"9","author":"Cervera-Martinez","year":"2018","journal-title":"Front. Neurol."},{"issue":"8","key":"10.1016\/j.clineuro.2020.106397_bib0065","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1046\/j.1526-4610.2003.03172.x","article-title":"Familial trigeminal neuralgia: case reports and review of the literature","volume":"43","author":"Smyth","year":"2003","journal-title":"Headache"},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0070","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/00000658-193602000-00002","article-title":"Bilateral trigeminal tic: its association with heredity and disseminated sclerosis","volume":"103","author":"Harris","year":"1936","journal-title":"Ann. Surg."},{"issue":"3","key":"10.1016\/j.clineuro.2020.106397_bib0075","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/00007611-198503000-00030","article-title":"Familial trigeminal neuralgia","volume":"78","author":"DiCorato","year":"1985","journal-title":"South. Med. J."},{"issue":"5","key":"10.1016\/j.clineuro.2020.106397_bib0080","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1001\/archneur.1980.00500540063007","article-title":"Familial trigeminal neuralgia","volume":"37","author":"Herzberg","year":"1980","journal-title":"Arch. Neurol."},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0085","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s13566-017-0300-0","article-title":"Familial trigeminal neuralgia treated with stereotactic radiosurgery: a case report and literature review","volume":"6","author":"Denu","year":"2017","journal-title":"J. Radiat. Oncol."},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0090","doi-asserted-by":"crossref","first-page":"70","DOI":"10.5812\/aapm.2164","article-title":"Trigeminal neuralgia: frequency of occurrence in different nerve branches","volume":"1","author":"Bangash","year":"2011","journal-title":"Anesth. Pain Med."},{"key":"10.1016\/j.clineuro.2020.106397_bib0095","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2147\/TCRM.S37592","article-title":"Advances in diagnosis and treatment of trigeminal neuralgia","volume":"11","author":"Montano","year":"2015","journal-title":"Ther. Clin. Risk Manag."},{"issue":"5","key":"10.1016\/j.clineuro.2020.106397_bib0100","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.neurad.2012.08.006","article-title":"Imaging of vascular causes of trigeminal neuralgia","volume":"39","author":"Harsha","year":"2012","journal-title":"J. Neuroradiol."},{"issue":"3","key":"10.1016\/j.clineuro.2020.106397_bib0105","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3171\/jns.2002.96.3.0532","article-title":"Mechanism of trigeminal neuralgia: an ultrastructural analysis of trigeminal root specimens obtained during microvascular decompression surgery","volume":"96","author":"Devor","year":"2002","journal-title":"J. Neurosurg."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0110","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1001\/jamaneurol.2018.3322","article-title":"Familial trigeminal neuralgia cases implicate genetic factors in disease pathogenesis","volume":"76","author":"Panchagnula","year":"2019","journal-title":"JAMA Neurol."},{"issue":"6","key":"10.1016\/j.clineuro.2020.106397_bib0115","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.3171\/2014.2.JNS131288","article-title":"Atrophic changes in the trigeminal nerves of patients with trigeminal neuralgia due to neurovascular compression and their association with the severity of compression and clinical outcomes","volume":"120","author":"Leal","year":"2014","journal-title":"J. Neurosurg."},{"issue":"6","key":"10.1016\/j.clineuro.2020.106397_bib0120","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.3171\/2014.11.JNS141741","article-title":"Trigeminal neuralgia without neurovascular compression presents earlier than trigeminal neuralgia with neurovascular compression","volume":"123","author":"Ko","year":"2015","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.clineuro.2020.106397_bib0125","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3389\/fnana.2016.00095","article-title":"Structural magnetic resonance imaging can identify trigeminal system abnormalities in classical trigeminal neuralgia","volume":"10","author":"DeSouza","year":"2016","journal-title":"Front. Neuroanat."},{"issue":"8","key":"10.1016\/j.clineuro.2020.106397_bib0130","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.pain.2014.04.020","article-title":"Magnetic resonance imaging contribution for diagnosing symptomatic neurovascular contact in classical trigeminal neuralgia: a blinded case-control study and meta-analysis","volume":"155","author":"Antonini","year":"2014","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0135","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/00002508-200201000-00002","article-title":"Pathophysiology of trigeminal neuralgia: the ignition hypothesis","volume":"18","author":"Devor","year":"2002","journal-title":"Clin. J. Pain"},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0140","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0304-3959(94)90086-8","article-title":"Trigeminal neuralgia: the role of self-sustaining discharge in the trigeminal ganglion","volume":"56","author":"Rappaport","year":"1994","journal-title":"Pain"},{"issue":"5","key":"10.1016\/j.clineuro.2020.106397_bib0145","first-page":"872","article-title":"Pathophysiology of trigeminal neuralgia: new evidence from a trigeminal ganglion intraoperative microneurographic recording","volume":"101","author":"Burchiel","year":"2004","journal-title":"Case report. J Neurosurg."},{"key":"10.1016\/j.clineuro.2020.106397_bib0150","doi-asserted-by":"crossref","first-page":"338","DOI":"10.2119\/molmed.2016.00131","article-title":"A gain-of-function mutation in Nav1.6 in a case of trigeminal neuralgia","volume":"22","author":"Tanaka","year":"2016","journal-title":"Mol Med."},{"issue":"Suppl 1","key":"10.1016\/j.clineuro.2020.106397_bib0155","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1097\/j.pain.0000000000000854","article-title":"Sodium channels in pain disorders: pathophysiology and prospects for treatment","volume":"158","author":"Dib-Hajj","year":"2017","journal-title":"Pain"},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0160","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.neuroscience.2009.08.037","article-title":"Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia","volume":"164","author":"Siqueira","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.clineuro.2020.106397_bib0165","first-page":"72","article-title":"The role of Nav1.9 channel in the development of neuropathic orofacial pain associated with trigeminal neuralgia","volume":"11","author":"Luiz","year":"2015","journal-title":"Mol. Pain"},{"issue":"12","key":"10.1016\/j.clineuro.2020.106397_bib0170","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1097\/WNR.0000000000000632","article-title":"Changes in the expression of voltage-gated sodium channels Nav1.3, Nav1.7, Nav1.8, and Nav1.9 in rat trigeminal ganglia following chronic constriction injury","volume":"27","author":"Xu","year":"2016","journal-title":"Neuroreport"},{"issue":"7","key":"10.1016\/j.clineuro.2020.106397_bib0175","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1093\/pm\/pny191","article-title":"No association of polymorphisms in Nav1.7 or nerve growth factor receptor genes with trigeminal neuralgia","volume":"20","author":"Costa","year":"2019","journal-title":"Pain Med."},{"issue":"16","key":"10.1016\/j.clineuro.2020.106397_bib0180","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.1523\/JNEUROSCI.5053-07.2008","article-title":"Silencing the Kir4.1 potassium channel subunit in satellite glial cells of the rat trigeminal ganglion results in pain-like behavior in the absence of nerve injury","volume":"28","author":"Vit","year":"2008","journal-title":"J. Neurosci."},{"issue":"9","key":"10.1016\/j.clineuro.2020.106397_bib0185","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1016\/j.pain.2011.05.023","article-title":"Peripheral inflammation suppresses inward rectifying potassium currents of satellite glial cells in the trigeminal ganglia","volume":"152","author":"Takeda","year":"2011","journal-title":"Pain"},{"issue":"8","key":"10.1016\/j.clineuro.2020.106397_bib0190","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1073\/pnas.1600418113","article-title":"Pathophysiological implication of CaV3.1 T-type Ca2+ channels in trigeminal neuropathic pain","volume":"113","author":"Choi","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"Pt 5","key":"10.1016\/j.clineuro.2020.106397_bib0195","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1093\/brain\/aww038","article-title":"TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes\/macrophages and oxidative stress","volume":"139","author":"Trevisan","year":"2016","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0200","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1129-2377-15-42","article-title":"The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in idiopathic trigeminal neuralgia patients","volume":"15","author":"Cui","year":"2014","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.clineuro.2020.106397_bib0205","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1744-8069-6-8","article-title":"Trigeminal injury causes kappa opioid-dependent allodynic, glial and immune cell responses in mice","volume":"6","author":"Aita","year":"2010","journal-title":"Mol. Pain"},{"issue":"2","key":"10.1016\/j.clineuro.2020.106397_bib0210","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/ALN.0b013e3182604b2b","article-title":"Trigeminal nerve injury ErbB3\/ErbB2 promotes mechanical hypersensitivity","volume":"117","author":"Ma","year":"2012","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1016\/j.clineuro.2020.106397_bib0215","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1111\/jnc.13584","article-title":"Transcriptional repressor DREAM regulates trigeminal noxious perception","volume":"141","author":"Benedet","year":"2017","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst. Rev."},{"issue":"22","key":"10.1016\/j.clineuro.2020.106397_bib0225","first-page":"4825","article-title":"Resurgent current of voltage-gated Na(+) channels","volume":"592","author":"Lewis","year":"2014","journal-title":"J. Physiol. (Paris)"},{"issue":"11","key":"10.1016\/j.clineuro.2020.106397_bib0230","doi-asserted-by":"crossref","first-page":"5148","DOI":"10.1073\/pnas.0913181107","article-title":"Pain perception is altered by a nucleotide polymorphism in SCN9A","volume":"107","author":"Reimann","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0235","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.rmed.2012.09.024","article-title":"Neurotrophin serum concentrations and polymorphisms of neurotrophins and their receptors in children with asthma","volume":"107","author":"Szczepankiewicz","year":"2013","journal-title":"Respir. Med."},{"key":"10.1016\/j.clineuro.2020.106397_bib0240","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.neulet.2017.10.029","article-title":"Associations between single-nucleotide polymorphisms in the NTRK1 gene and basal pain sensitivity in young Han Chinese women","volume":"662","author":"Li","year":"2018","journal-title":"Neurosci. Lett."},{"issue":"4886","key":"10.1016\/j.clineuro.2020.106397_bib0245","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1126\/science.3059497","article-title":"The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function","volume":"242","author":"Llin\u00e1s","year":"1988","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.clineuro.2020.106397_bib0250","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1152\/physrev.1988.68.3.649","article-title":"The functional states of the thalamus and the associated neuronal interplay","volume":"68","author":"Steriade","year":"1988","journal-title":"Physiol. Rev."},{"issue":"4","key":"10.1016\/j.clineuro.2020.106397_bib0255","first-page":"181","article-title":"Spinal cord microglial cells and DRG satellite cells rapidly respond to transection of the rat sciatic nerve","volume":"2","author":"Gehrmann","year":"1991","journal-title":"Restor. Neurol. Neurosci."},{"issue":"5","key":"10.1016\/j.clineuro.2020.106397_bib0260","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1007\/BF01195557","article-title":"Responses of macrophages in rat dorsal root ganglia following peripheral nerve injury","volume":"22","author":"Lu","year":"1993","journal-title":"J. Neurocytol."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106397_bib0265","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0306-4522(02)00065-9","article-title":"Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat","volume":"112","author":"Hu","year":"2002","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.clineuro.2020.106397_bib0270","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s10059-010-0137-5","article-title":"Secretion of EGF-like domain of heregulin\u03b2 promotes axonal growth and functional recovery of injured sciatic nerve","volume":"30","author":"Joung","year":"2010","journal-title":"Mol. Cells"},{"issue":"12","key":"10.1016\/j.clineuro.2020.106397_bib0275","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1038\/nn1797","article-title":"Bace1 modulates myelination in the central and peripheral nervous system","volume":"9","author":"Hu","year":"2006","journal-title":"Nat. Neurosci."},{"issue":"6722","key":"10.1016\/j.clineuro.2020.106397_bib0280","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/18044","article-title":"DREAM is a Ca2+-regulated transcriptional repressor","volume":"398","author":"Carri\u00f3n","year":"1999","journal-title":"Nature"},{"issue":"6769","key":"10.1016\/j.clineuro.2020.106397_bib0285","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/35000592","article-title":"Modulation of A-type potassium channels by a family of calcium sensors","volume":"403","author":"An","year":"2000","journal-title":"Nature"},{"issue":"47","key":"10.1016\/j.clineuro.2020.106397_bib0290","doi-asserted-by":"crossref","first-page":"10822","DOI":"10.1523\/JNEUROSCI.3912-05.2005","article-title":"Downstream regulatory element antagonist modulator regulates Ca2+ homeostasis and viability in cerebellar neurons","volume":"25","author":"Gomez-Villafuertes","year":"2005","journal-title":"J. Neurosci."},{"issue":"20","key":"10.1016\/j.clineuro.2020.106397_bib0295","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1038\/sj.emboj.7600810","article-title":"Transcriptional repressor DREAM regulates T-lymphocyte proliferation and cytokine gene expression","volume":"24","author":"Savignac","year":"2005","journal-title":"EMBO J."},{"issue":"5","key":"10.1016\/j.clineuro.2020.106397_bib0300","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1128\/MCB.00360-13","article-title":"DREAM controls the on\/off switch of specific activity-dependent transcription pathways","volume":"34","author":"Mellstr\u00f6m","year":"2014","journal-title":"Mol. Cell. Biol."},{"issue":"23","key":"10.1016\/j.clineuro.2020.106397_bib0305","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.1523\/JNEUROSCI.1460-04.2004","article-title":"Day-night changes in downstream regulatory element antagonist modulator\/potassium channel interacting protein activity contribute to circadian gene expression in pineal gland","volume":"24","author":"Link","year":"2004","journal-title":"J. Neurosci."}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030384672030740X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030384672030740X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:34:48Z","timestamp":1759588488000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030384672030740X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":61,"alternative-id":["S030384672030740X"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2020.106397","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular mechanisms of trigeminal neuralgia: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurology and Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clineuro.2020.106397","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106397"}}