{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T06:34:05Z","timestamp":1793860445595,"version":"4.6.1"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurology and Neurosurgery"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.clineuro.2020.106435","type":"journal-article","created":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T03:52:28Z","timestamp":1608090748000},"page":"106435","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Hypertonic saline buffered with sodium acetate for intracranial pressure management"],"prefix":"10.1016","volume":"201","author":[{"given":"Devin N.","family":"Holden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine H.","family":"Yung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pouya","family":"Entezami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.clineuro.2020.106435_bib0005","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ncl.2008.02.003","article-title":"Management of intracranial hypertension","volume":"26","author":"Rangel-Castilla","year":"2008","journal-title":"Neurol. Clin."},{"issue":"9","key":"10.1016\/j.clineuro.2020.106435_bib0010","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1097\/00003246-200009000-00032","article-title":"Use of hypertonic saline solutions in treatment of cerebral edema and intracranial hypertension","volume":"28","author":"Qureshi","year":"2000","journal-title":"Crit. Care Med."},{"issue":"3","key":"10.1016\/j.clineuro.2020.106435_bib0015","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1172\/JCI110820","article-title":"Regulation of renal blood flow by plasma chloride","volume":"71","author":"Wilcox","year":"1983","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106435_bib0020","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/SLA.0b013e318256be72","article-title":"A randomized, controlled, double-blind crossover study on the effects of 2-L infusions of 0.9% saline and plasma-lyte(R) 148 on renal blood flow velocity and renal cortical tissue perfusion in healthy volunteers","volume":"256","author":"Chowdhury","year":"2012","journal-title":"Ann. Surg."},{"issue":"9","key":"10.1016\/j.clineuro.2020.106435_bib0025","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/nep.12840","article-title":"Hyperchloremic acidosis is associated with acute kidney injury after abdominal surgery","volume":"22","author":"Toyonaga","year":"2017","journal-title":"Nephrology (Carlton, Vic.)"},{"key":"10.1016\/j.clineuro.2020.106435_bib0030","doi-asserted-by":"crossref","DOI":"10.1093\/ajhp\/zxaa226","article-title":"Errors with extemporaneous compounding of buffered hypertonic saline","author":"Cook","year":"2020","journal-title":"Am. J. Health. Syst. Pharm."},{"issue":"6","key":"10.1016\/j.clineuro.2020.106435_bib0035","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1161\/01.HYP.32.6.1066","article-title":"Chloride regulates afferent arteriolar contraction in response to depolarization","volume":"32","author":"Hansen","year":"1998","journal-title":"Hypertension (Dallas, Tex.: 1979)"},{"issue":"20","key":"10.1016\/j.clineuro.2020.106435_bib0040","first-page":"1950","article-title":"Balanced crystalloids versus saline in critically ill adults","volume":"378","author":"Barea-Mendoza","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106435_bib0045","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13613-019-0506-y","article-title":"Effects of chloride content of intravenous crystalloid solutions in critically ill adult patients: a meta-analysis with trial sequential analysis of randomized trials","volume":"9","author":"Xue","year":"2019","journal-title":"Ann. Intensive Care"},{"issue":"6","key":"10.1016\/j.clineuro.2020.106435_bib0050","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/ki.2014.105","article-title":"Should chloride-rich crystalloids remain the mainstay of fluid resuscitation to prevent\u2019 pre-renal\u2019 acute kidney injury?: con","volume":"86","author":"Lobo","year":"2014","journal-title":"Kidney Int."},{"issue":"8","key":"10.1016\/j.clineuro.2020.106435_bib0055","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1097\/CCM.0000000000002497","article-title":"Hyperchloremia is associated with acute kidney injury in patients with subarachnoid hemorrhage","volume":"45","author":"Sadan","year":"2017","journal-title":"Crit. Care Med."},{"issue":"9","key":"10.1016\/j.clineuro.2020.106435_bib0060","doi-asserted-by":"crossref","first-page":"e947","DOI":"10.1097\/CCM.0000000000002522","article-title":"Impact of moderate hyperchloremia on clinical outcomes in intracerebral hemorrhage patients treated with continuous infusion hypertonic saline: a pilot study","volume":"45","author":"Riha","year":"2017","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.clineuro.2020.106435_bib0065","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3389\/fneur.2018.00485","article-title":"Hyperchloremia is associated with poorer outcome in critically ill stroke patients","volume":"9","author":"Huang","year":"2018","journal-title":"Front. Neurol."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106435_bib0070","first-page":"3","article-title":"Intravenous fluid therapy in traumatic brain injury and decompressive craniectomy","volume":"2","author":"Alvis-Miranda","year":"2014","journal-title":"Bull. Emerg. Trauma"},{"issue":"3","key":"10.1016\/j.clineuro.2020.106435_bib0075","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/00003246-199803000-00011","article-title":"Use of hypertonic (3%) saline\/acetate infusion in the treatment of cerebral edema: effect on intracranial pressure and lateral displacement of the brain","volume":"26","author":"Qureshi","year":"1998","journal-title":"Crit. Care Med."},{"issue":"1","key":"10.1016\/j.clineuro.2020.106435_bib0080","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1186\/s13063-018-3007-7","article-title":"Low-chloride versus high-chloride hypertonic solution for the treatment of subarachnoid hemorrhage-related complications (The ACETatE trial): study protocol for a pilot randomized controlled trial","volume":"19","author":"Sadan","year":"2018","journal-title":"Trials"}],"container-title":["Clinical Neurology and Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846720307782?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303846720307782?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:35:09Z","timestamp":1759588509000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303846720307782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":16,"alternative-id":["S0303846720307782"],"URL":"https:\/\/doi.org\/10.1016\/j.clineuro.2020.106435","relation":{},"ISSN":["0303-8467"],"issn-type":[{"value":"0303-8467","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypertonic saline buffered with sodium acetate for intracranial pressure management","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurology and Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clineuro.2020.106435","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"106435"}}