{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T16:57:17Z","timestamp":1781974637410,"version":"3.54.5"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.clinph.2007.01.001","type":"journal-article","created":{"date-parts":[[2007,2,17]],"date-time":"2007-02-17T07:03:40Z","timestamp":1171695820000},"page":"1144-1148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Is excitation\u2013contraction coupling impaired in myasthenia gravis?"],"prefix":"10.1016","volume":"118","author":[{"given":"Miho","family":"Nakata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Kuwabara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokatsu","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonoko","family":"Misawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Kanai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Setsu","family":"Sawai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakatsu","family":"Motomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Shiraishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaharu","family":"Takamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Maruta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Yoshikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takamichi","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinph.2007.01.001_bib1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1365-2249.1990.tb05440.x","article-title":"Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin","volume":"82","author":"Aarli","year":"1990","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.clinph.2007.01.001_bib2","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1749-6632.1998.tb10971.x","article-title":"Muscle striation antibodies in myasthenia gravis: diagnostic and functional significance","volume":"841","author":"Aarli","year":"1998","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.clinph.2007.01.001_bib3","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1136\/jnnp.43.7.601","article-title":"Mechanisms of acetylcholine receptor loss in myasthenia gravis","volume":"43","author":"Drachman","year":"1980","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.clinph.2007.01.001_bib4","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/BF00712033","article-title":"Junctional feet and particles in the triads of a fast-twitch muscle fibre","volume":"4","author":"Franzini-Armstrong","year":"1983","journal-title":"J Muscle Res Cell Motil"},{"key":"10.1016\/j.clinph.2007.01.001_bib5","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1002\/(SICI)1097-4598(199812)21:12<1655::AID-MUS5>3.0.CO;2-F","article-title":"Spontaneous thymoma rat as a model for myasthenic weakness caused by anti-ryanodine receptor antibodies","volume":"21","author":"Iwasa","year":"1998","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2007.01.001_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1212\/WNL.55.1.16","article-title":"Myasthenia gravis: recommendations for clinical research standards","volume":"55","author":"Jaretzki","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2007.01.001_bib7","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1136\/jnnp.40.3.241","article-title":"Electrical and mechanical responses in the platysma and in the adductor pollicis muscle: in patients with myasthenia gravis","volume":"40","author":"Krarup","year":"1977","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.clinph.2007.01.001_bib8","doi-asserted-by":"crossref","first-page":"7791","DOI":"10.1074\/jbc.273.14.7791","article-title":"A 37-amino acid sequence in the skeletal muscle ryanodine receptor interacts with the cytoplasmic loop between domains II and III in the skeletal muscle dihydropyridine receptor","volume":"273","author":"Leong","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.clinph.2007.01.001_bib9","doi-asserted-by":"crossref","first-page":"29958","DOI":"10.1074\/jbc.273.45.29958","article-title":"The cytoplasmic loops between domains II and III and domains III and IV in the skeletal muscle dihydropyridine receptor bind to a contiguous site in the skeletal muscle ryanodine receptor","volume":"273","author":"Leong","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.clinph.2007.01.001_bib10","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1212\/WNL.26.11.1054","article-title":"Antibody to acetylcholine receptor in myasthenia gravis: prevalence, clinical correlates, and diagnostic value","volume":"26","author":"Lindstrom","year":"1976","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2007.01.001_bib11","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/ana.410320419","article-title":"Ryanodine receptor autoantibodies in myasthenia gravis patients with a thymoma","volume":"32","author":"Mygland","year":"1992","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clinph.2007.01.001_bib12","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1136\/jnnp.2004.043125","article-title":"Patterns and severity of neuromuscular transmission failure in seronegative myasthenia gravis","volume":"76","author":"Nemoto","year":"2005","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.clinph.2007.01.001_bib13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0009-8981(90)90110-E","article-title":"Anti-skeletal muscle antibodies in the sera from myasthenic patients with thymoma: identification of anti-myosin, actomyosin, actin, and \u03b1-actinin antibodies by a solid-phase radioimmunoassay and a Western blotting analysis","volume":"187","author":"Ohta","year":"1990","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.clinph.2007.01.001_bib14","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1136\/jnnp.36.2.244","article-title":"Neurogenic muscle involvement in myasthenia gravis: a clinical and histopathological study","volume":"36","author":"Oosterhuis","year":"1973","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.clinph.2007.01.001_bib15","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0022-510X(83)90096-5","article-title":"Anti-acetylcholine receptor antibodies in myasthenia gravis: clinical and serological follow-up of individual patients","volume":"58","author":"Oosterhuis","year":"1983","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.clinph.2007.01.001_bib16","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1002\/mus.880131103","article-title":"Responses of intercostal muscle biopsies form normal subjects and patients with myasthenia gravis","volume":"13","author":"Pagala","year":"1990","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2007.01.001_bib17","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1002\/mus.880160905","article-title":"Mechanisms of fatigue in normal intercostal muscle and muscle form patients with myasthenia gravis","volume":"16","author":"Pagala","year":"1993","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2007.01.001_bib18","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/mus.880090505","article-title":"Antimuscle and antiacetylcholine receptor antibodies in myasthenia gravis","volume":"9","author":"Penn","year":"1986","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2007.01.001_bib19","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/ana.20341","article-title":"Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis","volume":"57","author":"Shiraishi","year":"2005","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clinph.2007.01.001_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(68)90227-8","article-title":"Electrical and mechanical responses of normal and myasthenic muscle: with particular reference to the staircase phonimenon","volume":"10","author":"Slomi\u0107","year":"1968","journal-title":"Brain Res"},{"key":"10.1016\/j.clinph.2007.01.001_bib21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0168-5597(93)90088-7","article-title":"Neurophysiological evaluation in myasthenia gravis: a comprehensive study of a complete patient population","volume":"89","author":"Somnier","year":"1993","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2007.01.001_bib22","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1046\/j.1468-1331.1999.650555.x","article-title":"EMG evidence of myopathy and the occurrence of titin autoantibodies in patients with myasthenia gravis","volume":"6","author":"Somnier","year":"1999","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.clinph.2007.01.001_bib23","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/j.1749-6632.1965.tb18999.x","article-title":"Immunological concomitants of myasthenia gravis","volume":"124","author":"Strauss","year":"1965","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.clinph.2007.01.001_bib24","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1212\/01.WNL.0000125254.99397.68","article-title":"Anti-ryanodine receptor antibodies and FK506 in myasthenia gravis","volume":"62","author":"Takamori","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2007.01.001_bib25","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/346567a0","article-title":"Regions of the skeletal muscle dihydropyridine receptor critical for excitation\u2013contraction coupling","volume":"346","author":"Tanabe","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.clinph.2007.01.001_bib26","doi-asserted-by":"crossref","first-page":"22992","DOI":"10.1016\/S0021-9258(19)49416-7","article-title":"The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein: dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum","volume":"268","author":"Timerman","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.clinph.2007.01.001_bib27","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1136\/jnnp.48.12.1246","article-title":"Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays","volume":"48","author":"Vincent","year":"1985","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.clinph.2007.01.001_bib28","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1016\/S0021-9258(19)39968-5","article-title":"Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum","volume":"265","author":"Zorzato","year":"1990","journal-title":"J Biol Chem"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245707000053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245707000053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T10:38:53Z","timestamp":1761388733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245707000053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S1388245707000053"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2007.01.001","relation":{},"ISSN":["1388-2457"],"issn-type":[{"value":"1388-2457","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is excitation\u2013contraction coupling impaired in myasthenia gravis?","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2007.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}