{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T02:43:29Z","timestamp":1792205009470,"version":"4.4.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.clinph.2013.05.026","type":"journal-article","created":{"date-parts":[[2013,7,15]],"date-time":"2013-07-15T15:46:09Z","timestamp":1373903169000},"page":"53-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Auditory post-processing in a passive listening task is deficient in Alzheimer\u2019s disease"],"prefix":"10.1016","volume":"125","author":[{"given":"Stephan","family":"Bender","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annet","family":"Bluschke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Dippel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Rupp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Weisbrod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinph.2013.05.026_b0005","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1176\/ajp.161.10.1822","article-title":"Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients","volume":"161","author":"Adler","year":"2004","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.clinph.2013.05.026_b0010","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1177\/1533317506292282","article-title":"Sensory gating in patients with Alzheimer\u2019s disease and their biological children","volume":"21","author":"Ally","year":"2006","journal-title":"Am J Alzheimers Dis Other Demen"},{"key":"10.1016\/j.clinph.2013.05.026_b0015","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.schres.2010.03.007","article-title":"MEG does not reveal impaired sensory gating in first-episode schizophrenia","volume":"121","author":"Bachmann","year":"2010","journal-title":"Schizophr Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0020","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1055\/s-2004-830249","article-title":"Mild cognitive impairment and Alzheimer\u2019s disease: an investigation of the CERAD-NP test battery","volume":"73","author":"Barth","year":"2005","journal-title":"Fortschr Neurol Psychiatr"},{"key":"10.1016\/j.clinph.2013.05.026_b0025","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1016\/j.clinph.2010.05.008","article-title":"Transmodal comparison of auditory, motor, and visual post-processing with and without intentional short-term memory maintenance","volume":"121","author":"Bender","year":"2010","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0030","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1159\/000255240","article-title":"Single- and multiple-domain amnestic mild cognitive impairment: two sides of the same coin?","volume":"28","author":"Brambati","year":"2009","journal-title":"Dement Geriatr Cogn Disord"},{"key":"10.1016\/j.clinph.2013.05.026_b0035","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.neurobiolaging.2008.02.021","article-title":"Disturbance of automatic auditory change detection in dementia associated with Parkinson\u2019s disease: a mismatch negativity study","volume":"31","author":"Br\u00f8nnick","year":"2010","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.clinph.2013.05.026_b0040","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0167-8760(01)00179-9","article-title":"Wait and see","volume":"43","author":"Brunia","year":"2001","journal-title":"Int J Psychophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0045","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0013-4694(88)90132-0","article-title":"Distribution of slow brain potentials related to motor preparation and stimulus anticipation in a time estimation task","volume":"69","author":"Brunia","year":"1988","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0050","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/01.wnp.0000218991.99714.ee","article-title":"Sensory gating deficit assessed by P50\/Pb middle latency event related potential in Alzheimer\u2019s disease","volume":"23","author":"Cancelli","year":"2006","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0055","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.neurobiolaging.2005.03.012","article-title":"Auditory sensory memory and the aging brain: a mismatch negativity study","volume":"27","author":"Cooper","year":"2006","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.clinph.2013.05.026_b0060","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/BF01067637","article-title":"Working memory as a predictor of verbal fluency","volume":"20","author":"Daneman","year":"1991","journal-title":"J Psycholinguist Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0065","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.bandc.2008.12.007","article-title":"Response speed, contingent negative variation and P300 in Alzheimer\u2019s disease and MCI","volume":"69","author":"Van Deursen","year":"2009","journal-title":"Brain Cogn"},{"key":"10.1016\/j.clinph.2013.05.026_b0070","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0022-510X(95)00093-H","article-title":"Utility of auditory P300 in detection of presenile dementia","volume":"131","author":"Filipovi\u0107","year":"1995","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.clinph.2013.05.026_b0075","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0197-4580(96)00072-3","article-title":"Automatic and effortful processing in aging and dementia: event-related brain potentials","volume":"18","author":"Ford","year":"1997","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.clinph.2013.05.026_b0080","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.schres.2010.04.020","article-title":"Relationships between sensory \u201cgating out\u201d and sensory \u201cgating in\u201d of auditory evoked potentials in schizophrenia: a pilot study","volume":"121","author":"Gjini","year":"2010","journal-title":"Schizophr Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0085","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/gerona\/glr067","article-title":"Age effects on preattentive and early attentive auditory processing of redundant stimuli: is sensory gating affected by physiological aging?","volume":"66","author":"Gmehlin","year":"2011","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.clinph.2013.05.026_b0090","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/S1388-2457(00)00332-1","article-title":"Effects of stimulus sequence on event-related potentials and reaction time during target detection in Alzheimer\u2019s disease","volume":"111","author":"Golob","year":"2000","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0095","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/ajmg.b.30318","article-title":"Genetic overlap between P300, P50, and duration mismatch negativity","volume":"141B","author":"Hall","year":"2006","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.clinph.2013.05.026_b0100","doi-asserted-by":"crossref","first-page":"e17482","DOI":"10.1371\/journal.pone.0017482","article-title":"Aging and error processing: age related increase in the variability of the error-negativity is not accompanied by increase in response variability","volume":"6","author":"Hoffmann","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.clinph.2013.05.026_b0105","doi-asserted-by":"crossref","first-page":"S137","DOI":"10.1016\/j.jalz.2007.10.008","article-title":"Electroencephalography and event-related potentials as biomarkers of mild cognitive impairment and mild Alzheimer\u2019s disease","volume":"4","author":"Jackson","year":"2008","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.clinph.2013.05.026_b0110","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1176\/appi.ajp.158.8.1319","article-title":"Sensory gating deficit expressed by a disturbed suppression of the P50 event-related potential in patients with Alzheimer\u2019s disease","volume":"158","author":"Jessen","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.clinph.2013.05.026_b0115","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/WAD.0b013e3182076d31","article-title":"Cortical thinning in verbal, visual, and both memory-predominant mild cognitive impairment","volume":"25","author":"Kim","year":"2011","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"10.1016\/j.clinph.2013.05.026_b0120","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.cogbrainres.2005.09.014","article-title":"Age-related change in neural processing of time-dependent stimulus features","volume":"25","author":"Kisley","year":"2005","journal-title":"Brain Res Cogn Brain Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0125","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1111\/j.1469-8986.2004.00191.x","article-title":"Comparison of sensory gating to mismatch negativity and self-reported perceptual phenomena in healthy adults","volume":"41","author":"Kisley","year":"2004","journal-title":"Psychophysiology"},{"key":"10.1016\/j.clinph.2013.05.026_b0130","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.schres.2004.12.016","article-title":"Tropisetron improves deficits in auditory P50 suppression in schizophrenia","volume":"76","author":"Koike","year":"2005","journal-title":"Schizophr Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0135","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0301-0511(95)05108-2","article-title":"Assessment of mental workload with task-irrelevant auditory probes","volume":"40","author":"Kramer","year":"1995","journal-title":"Biol Psychol"},{"key":"10.1016\/j.clinph.2013.05.026_b0140","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF02252964","article-title":"Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer\u2019s disease: correlation with memory functions","volume":"9","author":"Laakso","year":"1995","journal-title":"J Neural Transm Park Dis Dement Sect"},{"key":"10.1016\/j.clinph.2013.05.026_b0145","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.clinph.2009.11.001","article-title":"The role of event-related potentials in cognitive decline in Alzheimer\u2019s disease","volume":"121","author":"Lai","year":"2010","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0150","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1111\/j.1469-8986.2009.00845.x","article-title":"P50, N100, and P200 sensory gating: relationships with behavioral inhibition, attention, and working memory","volume":"46","author":"Lijffijt","year":"2009","journal-title":"Psychophysiology"},{"key":"10.1016\/j.clinph.2013.05.026_b0155","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0197-4580(02)00154-9","article-title":"Response-monitoring dysfunction in aging and Alzheimer\u2019s disease: an event-related potential study","volume":"24","author":"Mathalon","year":"2003","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.clinph.2013.05.026_b0160","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer\u2019s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer\u2019s disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2013.05.026_b0165","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1212\/WNL.39.9.1159","article-title":"The Consortium to Establish a Registry for Alzheimer\u2019s Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer\u2019s disease","volume":"39","author":"Morris","year":"1989","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2013.05.026_b0170","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1001\/archpsyc.63.6.630","article-title":"Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia","volume":"63","author":"Olincy","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.clinph.2013.05.026_b0175","doi-asserted-by":"crossref","first-page":"295","DOI":"10.2174\/156720510791162421","article-title":"Combination of P300 and CSF \u03b2-amyloid(1\u201342) assays may provide a potential tool in the early diagnosis of Alzheimer\u2019s disease","volume":"7","author":"Papaliagkas","year":"2010","journal-title":"Curr Alzheimer Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0180","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.psychres.2007.02.009","article-title":"P50 sensory gating ratios in schizophrenics and controls: a review and data analysis","volume":"158","author":"Patterson","year":"2008","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0185","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000013883","article-title":"Mismatch negativity in aging and in Alzheimer\u2019s and Parkinson\u2019s diseases","volume":"5","author":"Pekkonen","year":"2000","journal-title":"Audiol Neurootol"},{"key":"10.1016\/j.clinph.2013.05.026_b0190","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1016\/S1388-2457(99)00153-4","article-title":"Impaired preconscious auditory processing and cognitive functions in Alzheimer\u2019s disease","volume":"110","author":"Pekkonen","year":"1999","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0195","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1097\/00001756-199412000-00033","article-title":"Auditory sensory memory impairment in Alzheimer\u2019s disease: an event-related potential study","volume":"5","author":"Pekkonen","year":"1994","journal-title":"Neuroreport"},{"key":"10.1016\/j.clinph.2013.05.026_b0200","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/03610739608254005","article-title":"Aging effects on auditory processing: an event-related potential study","volume":"22","author":"Pekkonen","year":"1996","journal-title":"Exp Aging Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0205","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1093\/brain\/awp075","article-title":"The neural correlates of verbal short-term memory in Alzheimer\u2019s disease: an fMRI study","volume":"132","author":"Peters","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.clinph.2013.05.026_b0210","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1093\/schbul\/sbj050","article-title":"Review of clinical correlates of P50 sensory gating abnormalities in patients with schizophrenia","volume":"32","author":"Potter","year":"2006","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.clinph.2013.05.026_b0215","first-page":"661","article-title":"Global Deterioration Scale (GDS)","volume":"24","author":"Reisberg","year":"1988","journal-title":"Psychopharmacol Bull"},{"key":"10.1016\/j.clinph.2013.05.026_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1751-228X.2011.01135.x","article-title":"Influence of verbal working memory depends on vocabulary: Oral reading fluency in adolescents with dyslexia","volume":"6","author":"Rose","year":"2012","journal-title":"Mind, Brain and Education"},{"key":"10.1016\/j.clinph.2013.05.026_b0225","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1017\/S0140525X03000165","article-title":"Working memory retention systems: a state of activated long-term memory","volume":"26","author":"Ruchkin","year":"2003","journal-title":"Behav Brain Sci"},{"key":"10.1016\/j.clinph.2013.05.026_b0230","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.neurobiolaging.2008.05.002","article-title":"P50 gating deficit in Alzheimer dementia correlates to frontal neuropsychological function","volume":"31","author":"Thomas","year":"2010","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.clinph.2013.05.026_b0235","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.psychres.2008.04.013","article-title":"Profile of auditory information-processing deficits in schizophrenia","volume":"165","author":"Turetsky","year":"2009","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.clinph.2013.05.026_b0240","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ijpsycho.2007.10.008","article-title":"P50 sensory gating and attentional performance","volume":"67","author":"Wan","year":"2008","journal-title":"Int J Psychophysiol"},{"key":"10.1016\/j.clinph.2013.05.026_b0245","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1212\/WNL.44.4.609","article-title":"The Consortium to Establish a Registry for Alzheimer\u2019s Disease (CERAD). Part V. A normative study of the neuropsychological battery","volume":"44","author":"Welsh","year":"1994","journal-title":"Neurology"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245713007049?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245713007049?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T11:18:19Z","timestamp":1761391099000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245713007049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S1388245713007049"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2013.05.026","relation":{},"ISSN":["1388-2457"],"issn-type":[{"value":"1388-2457","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Auditory post-processing in a passive listening task is deficient in Alzheimer\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2013.05.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}