{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:10:52Z","timestamp":1778616652271,"version":"3.51.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006379","name":"Office of Research and Development","doi-asserted-by":"publisher","award":["R13 NS057995"],"award-info":[{"award-number":["R13 NS057995"]}],"id":[{"id":"10.13039\/100006379","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["5U54 RR019498-05"],"award-info":[{"award-number":["5U54 RR019498-05"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["209583\/Z\/17\/Z"],"award-info":[{"award-number":["209583\/Z\/17\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G0601943"],"award-info":[{"award-number":["G0601943"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/M01827X\/1"],"award-info":[{"award-number":["MR\/M01827X\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R13 NS057995"],"award-info":[{"award-number":["R13 NS057995"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5 U54 NS059065-05S2"],"award-info":[{"award-number":["5 U54 NS059065-05S2"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.clinph.2019.12.414","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T11:57:40Z","timestamp":1580126260000},"page":"816-827","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["In vivo assessment of interictal sarcolemmal membrane properties in hypokalaemic and hyperkalaemic periodic paralysis"],"prefix":"10.1016","volume":"131","author":[{"given":"S. Veronica","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Suetterlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roope","family":"M\u00e4nnikk\u00f6","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugh","family":"Bostock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinph.2019.12.414_b0005","doi-asserted-by":"crossref","first-page":"4762","DOI":"10.1523\/JNEUROSCI.19-12-04762.1999","article-title":"Activation and inactivation of the voltage-gated sodium channel: role of segment S5 revealed by a novel hyperkalaemic periodic paralysis mutation","volume":"19","author":"Bendahhou","year":"1999","journal-title":"J Neurosci"},{"key":"10.1016\/j.clinph.2019.12.414_b0010","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1212\/WNL.58.8.1266","article-title":"Impairment of slow inactivation as a common mechanism for periodic paralysis in DIIS4-S5","volume":"58","author":"Bendahhou","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2019.12.414_b0015","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/mus.23267","article-title":"Muscle velocity recovery cycles: effects of repetitive stimulation on two muscles","volume":"46","author":"Boerio","year":"2012","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0020","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/mus.23429","article-title":"Temperature dependency of human muscle velocity recovery cycles","volume":"46","author":"Bostock","year":"2012","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0025","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1002\/j.2040-4603.2015.tb00630.x","article-title":"Channelopathies of skeletal muscle excitability","volume":"5","author":"Cannon","year":"2015","journal-title":"Compr Physiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0030","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0896-6273(93)90321-H","article-title":"Functional expression of sodium channel mutations identified in families with periodic paralysis","volume":"10","author":"Cannon","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.clinph.2019.12.414_b0035","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1093\/brain\/awu292","article-title":"Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis","volume":"137","author":"Corrochano","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.clinph.2019.12.414_b0040","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/0896-6273(93)90168-Q","article-title":"Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis","volume":"10","author":"Cummins","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.clinph.2019.12.414_b0045","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1085\/jgp.200509337","article-title":"Resting potential-dependent regulation of the voltage sensitivity of sodium channel gating in rat skeletal muscle in vivo","volume":"126","author":"Filatov","year":"2005","journal-title":"J Gen Physiol"},{"issue":"1","key":"10.1016\/j.clinph.2019.12.414_b0050","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1113\/jphysiol.2001.013298","article-title":"Effects of chloride transport on bistable behaviour of the membrane potential in mouse skeletal muscle","volume":"542","author":"Foppen","year":"2002","journal-title":"J Physiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0055","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/ana.20241","article-title":"Electromyography guides toward subgroups of mutations in muscle channelopathies","volume":"56","author":"Fournier","year":"2004","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clinph.2019.12.414_b0060","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1152\/jn.1957.20.6.602","article-title":"Negative after-potential of frog's skeletal muscle","volume":"20","author":"Frank","year":"1957","journal-title":"J Neurophysiol"},{"issue":"20","key":"10.1016\/j.clinph.2019.12.414_b0065","doi-asserted-by":"crossref","first-page":"6417","DOI":"10.1113\/JP274638","article-title":"Elevated resting H(+) current in the R1239H type 1 hypokalaemic periodic paralysis mutated Ca(2+) channel","volume":"595","author":"Fuster","year":"2017","journal-title":"J Physiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0070","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S0959-4388(03)00065-5","article-title":"Mechanisms of sodium channel inactivation","volume":"13","author":"Goldin","year":"2003","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0075","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1212\/WNL.52.7.1447","article-title":"Defective slow inactivation of sodium channels contributes to familial periodic paralysis","volume":"52","author":"Hayward","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2019.12.414_b0080","first-page":"1437","article-title":"Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness","volume":"118","author":"Hayward","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1016\/j.clinph.2019.12.414_b0085","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1136\/jnnp-2011-300444","article-title":"Muscle ischaemia in patients with orthostatic hypotension assessed by velocity recovery cycles","volume":"82","author":"Humm","year":"2011","journal-title":"J Neurol Neurosurg Psychiat"},{"key":"10.1016\/j.clinph.2019.12.414_b0090","doi-asserted-by":"crossref","first-page":"4036","DOI":"10.1073\/pnas.0811277106","article-title":"K+-dependent paradoxical membrane depolarization and Na+ overload, major and reversible contributors to weakness by ion channel leaks","volume":"106","author":"Jurkat-Rott","year":"2009","journal-title":"Proc Natl Acad Sci"},{"issue":"4","key":"10.1016\/j.clinph.2019.12.414_b0095","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1085\/jgp.201812231","article-title":"Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis","volume":"151","author":"Mi","year":"2019","journal-title":"J Gen Physiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0100","doi-asserted-by":"crossref","first-page":"C259","DOI":"10.1152\/ajpcell.1999.276.1.C259","article-title":"Hyperkalemic periodic paralysis M1592V mutation modifies activation in human skeletal muscle Na+ channel","volume":"276","author":"Rojas","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0105","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/mus.880070205","article-title":"Hypokalemic periodic paralysis: in vitro investigation of muscle fiber membrane parameters","volume":"7","author":"Rudel","year":"1984","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0110","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/ana.22238","article-title":"Refined exercise testing can aid DNA-based diagnosis in muscle channelopathies","volume":"69","author":"Tan","year":"2011","journal-title":"Ann Neurol"},{"key":"10.1016\/j.clinph.2019.12.414_b0115","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/mus.23293","article-title":"Membrane dysfunction in Andersen-Tawil syndrome assessed by velocity recovery cycles","volume":"46","author":"Tan","year":"2012","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0120","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/mus.24069","article-title":"Chloride channels in myotonia congenita assessed by velocity recovery cycles","volume":"49","author":"Tan","year":"2014","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0125","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/mus.25025","article-title":"In vivo assessment of muscle membrane properties in myotonic dystrophy","volume":"54","author":"Tan","year":"2016","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0130","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/mus.25956","article-title":"In vivo assessment of muscle membrane properties in the sodium channel myotonias","volume":"57","author":"Tan","year":"2018","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0135","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1212\/WNL.33.11.1522","article-title":"Interictal conduction slowing in muscle fibers in hypokalemic periodic paralysis","volume":"33","author":"Troni","year":"1983","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2019.12.414_b0140","doi-asserted-by":"crossref","first-page":"4082","DOI":"10.1172\/JCI57398","article-title":"A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis","volume":"121","author":"Wu","year":"2011","journal-title":"J Clin Invest"},{"key":"10.1016\/j.clinph.2019.12.414_b0145","doi-asserted-by":"crossref","first-page":"4580","DOI":"10.1172\/JCI66091","article-title":"A calcium channel mutant mouse model of hypokalemic periodic paralysis","volume":"122","author":"Wu","year":"2012","journal-title":"J Clin Invest"},{"key":"10.1016\/j.clinph.2019.12.414_b0150","doi-asserted-by":"crossref","first-page":"12785","DOI":"10.1073\/pnas.91.26.12785","article-title":"Sodium channel mutations in paramyotonia congenita exhibit similar biophysical phenotypes in vitro","volume":"91","author":"Yang","year":"1994","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.clinph.2019.12.414_b0155","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/mus.21192","article-title":"Velocity recovery cycles of human muscle action potentials and their sensitivity to ischemia","volume":"39","author":"Z'Graggen","year":"2009","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clinph.2019.12.414_b0160","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.clinph.2010.01.024","article-title":"Velocity recovery cycles of human muscle action potentials in chronic renal failure","volume":"121","author":"Z'Graggen","year":"2010","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0165","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.clinph.2010.09.024","article-title":"Muscle membrane dysfunction in critical illness myopathy assessed by velocity recovery cycles","volume":"122","author":"Z'Graggen","year":"2011","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2019.12.414_b0170","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/mus.880110213","article-title":"The muscle fiber conduction velocity and power spectra in familial hypokalemic periodic paralysis","volume":"11","author":"Zwarts","year":"1988","journal-title":"Muscle Nerve"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245720300286?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245720300286?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T19:17:55Z","timestamp":1778613475000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245720300286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S1388245720300286"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2019.12.414","relation":{},"ISSN":["1388-2457"],"issn-type":[{"value":"1388-2457","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vivo assessment of interictal sarcolemmal membrane properties in hypokalaemic and hyperkalaemic periodic paralysis","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2019.12.414","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}