{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:10:48Z","timestamp":1761394248640,"version":"build-2065373602"},"reference-count":33,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.clinph.2021.07.021","type":"journal-article","created":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T14:00:25Z","timestamp":1629208825000},"page":"2342-2350","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effects of tapentadol and oxycodone on central processing of tonic pain"],"prefix":"10.1016","volume":"132","author":[{"given":"Rasmus Bach","family":"Nedergaard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tine Maria","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas Dahl","family":"Nissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esben Bolvig","family":"Mark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Brock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asbj\u00f8rn Mohr","family":"Drewes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinph.2021.07.021_b0005","first-page":"1999","article-title":"Treatment of neuropathic pain with venlafaxine: A systematic review","volume":"18","author":"Aiyer","year":"2017","journal-title":"Pain Med"},{"key":"10.1016\/j.clinph.2021.07.021_b0010","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ejpain.2004.03.001","article-title":"Visceral pain: Gender differences in response to experimental and clinical pain","volume":"8","author":"Arendt-Nielsen","year":"2004","journal-title":"Eur J Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0015","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/bja\/aet127","article-title":"Sex differences in pain: A brief review of clinical and experimental findings","volume":"111","author":"Bartley","year":"2013","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.clinph.2021.07.021_b0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fninf.2015.00016","article-title":"The PREP pipeline: standardized preprocessing for large-scale EEG analysis","volume":"9","author":"Bigdely-Shamlo","year":"2015","journal-title":"Front Neuroinform"},{"key":"10.1016\/j.clinph.2021.07.021_b0025","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0013-4694(98)00075-3","article-title":"Neurophysiological evaluation of pain","volume":"107","author":"Bromm","year":"1998","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2021.07.021_b0030","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(83)90088-X","article-title":"Assessment of chronic pain. I. Aspects of the reliability and validity of the visual analogue scale","volume":"16","author":"Carlsson","year":"1983","journal-title":"Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0035","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0361-9230(01)00763-8","article-title":"Dynamic changes and spatial correlation of EEG activities during cold pressor test in man","volume":"57","author":"Chang","year":"2002","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.clinph.2021.07.021_b0040","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.15585\/mmwr.mm6736a2","article-title":"Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults \u2014 United States, 2016","volume":"67","author":"Dahlhamer","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.clinph.2021.07.021_b0045","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1365-2125.2012.04317.x","article-title":"Differences between opioids: Pharmacological, experimental, clinical and economical perspectives","volume":"75","author":"Drewes","year":"2013","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.clinph.2021.07.021_b0050","first-page":"104","article-title":"The Effect of Overencapsulation on Disintegration and Dissolution","volume":"34","author":"Esseku","year":"2010","journal-title":"Pharm Technol"},{"key":"10.1016\/j.clinph.2021.07.021_b0055","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-010364","article-title":"Prevalence of chronic pain in the UK: A systematic review and meta-analysis of population studies","volume":"6","author":"Fayaz","year":"2016","journal-title":"BMJ Open"},{"key":"10.1016\/j.clinph.2021.07.021_b0060","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0167-8760(94)90068-X","article-title":"Quantitative EEG modifications during the cold water pressor test: hemispheric and hand differences","volume":"17","author":"Ferracuti","year":"1994","journal-title":"Int J Psychophysiol"},{"key":"10.1016\/j.clinph.2021.07.021_b0065","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10548-006-0011-0","article-title":"Spherical splines and average referencing in scalp electroencephalography","volume":"19","author":"Ferree","year":"2006","journal-title":"Brain Topogr"},{"key":"10.1016\/j.clinph.2021.07.021_b0070","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.jpain.2008.12.001","article-title":"Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings","volume":"10","author":"Fillingim","year":"2009","journal-title":"J Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0075","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.clinph.2014.07.027","article-title":"Dynamic spectral indices of the electroencephalogram provide new insights into tonic pain","volume":"126","author":"Gram","year":"2015","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2021.07.021_b0080","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2466\/pms.2003.96.1.201","article-title":"Pain perception across the menstrual cycle phases in women with chronic pain","volume":"96","author":"Hellstr\u00f6m","year":"2003","journal-title":"Percept Mot Skills"},{"key":"10.1016\/j.clinph.2021.07.021_b0085","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1002\/ejp.714","article-title":"Does pain vary across the menstrual cycle?","volume":"19","author":"Iacovides","year":"2015","journal-title":"A review. Eur J Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0090","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0304-3959(88)90156-X","article-title":"Morphine and ibuprofen compared using the cold pressor test","volume":"34","author":"Jones","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0095","first-page":"S605","article-title":"Selective serotonin re-uptake inhibitors: An overview","volume":"30","author":"Joshi","year":"2018","journal-title":"Psychiatr Danub"},{"key":"10.1016\/j.clinph.2021.07.021_b0100","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1177\/2049463716657363","article-title":"Is tapentadol different from classical opioids? A review of the evidence","volume":"10","author":"Langford","year":"2016","journal-title":"Br J Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0105","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1080\/03009742.2016.1218543","article-title":"Chronic pain in older adults: prevalence, incidence, and risk factors","volume":"46","author":"Larsson","year":"2017","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.clinph.2021.07.021_b0110","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.neuropharm.2017.06.022","article-title":"The effects of analgesics on central processing of tonic pain: A cross-over placebo controlled study","volume":"123","author":"Lelic","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.clinph.2021.07.021_b0115","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.xphs.2018.10.035","article-title":"Effect of Overencapsulation on the Disintegration and Dissolution of Licensed Formulations for Blinding in Randomized Controlled Trials","volume":"108","author":"Maher","year":"2019","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.clinph.2021.07.021_b0120","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/bcp.12137","article-title":"Electroencephalography and analgesics","volume":"77","author":"Malver","year":"2014","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.clinph.2021.07.021_b0125","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1515\/sjpain-2020-0151","article-title":"Although tapentadol and oxycodone both increase colonic volume, tapentadol treatment resulted in softer stools and less constipation: a mechanistic study in healthy volunteers","volume":"21","author":"Mark","year":"2021","journal-title":"Scand J Pain"},{"key":"10.1016\/j.clinph.2021.07.021_b0130","doi-asserted-by":"crossref","DOI":"10.1111\/nmo.14131","article-title":"Tapentadol results in less deterioration of gastrointestinal function and symptoms than standard opioid therapy in healthy male volunteers","author":"Mark","year":"2021","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.clinph.2021.07.021_b0135","first-page":"1","article-title":"Review of Methods for Solving the EEG Inverse Problem","volume":"1","author":"Pascual-Marqui","year":"1999","journal-title":"Int J Bioelectromagn"},{"key":"10.1016\/j.clinph.2021.07.021_b0140","doi-asserted-by":"crossref","first-page":"3768","DOI":"10.1098\/rsta.2011.0081","article-title":"Assessing interactions in the brain with exact low-resolution electromagnetic tomography","volume":"369","author":"Pascual-Marqui","year":"2011","journal-title":"Philos Trans R Soc A Math Phys Eng Sci"},{"key":"10.1016\/j.clinph.2021.07.021_b0145","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0167-8760(84)90014-X","article-title":"Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain","volume":"18","author":"Pascual-Marqui","year":"1994","journal-title":"Int J Psychophysiol"},{"key":"10.1016\/j.clinph.2021.07.021_b0150","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0013-4694(89)90180-6","article-title":"Spherical splines for scalp potential and current density mapping","volume":"72","author":"Perrin","year":"1989","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.clinph.2021.07.021_b0155","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0006-8993(00)02077-1","article-title":"The pain inhibiting pain effect: An electrophysiological study in humans","volume":"862","author":"Reinert","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.clinph.2021.07.021_b0160","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1007\/s11481-012-9378-8","article-title":"Visualizing the Complex Brain Dynamics of Chronic Pain","volume":"8","author":"Saab","year":"2013","journal-title":"J Neuroimmune Pharmacol"},{"key":"10.1016\/j.clinph.2021.07.021_b0165","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2125.2009.03456.x","article-title":"Assessing analgesic actions of opioids by experimental pain models in healthy volunteers - An updated review","volume":"68","author":"Staahl","year":"2009","journal-title":"Br J Clin Pharmacol"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245721006970?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245721006970?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:06:57Z","timestamp":1761394017000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245721006970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S1388245721006970"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2021.07.021","relation":{},"ISSN":["1388-2457"],"issn-type":[{"type":"print","value":"1388-2457"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of tapentadol and oxycodone on central processing of tonic pain","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2021.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}