{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:04:09Z","timestamp":1788455049490,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100018636","name":"Xuzhou Science and Technology Program","doi-asserted-by":"publisher","award":["KC22223"],"award-info":[{"award-number":["KC22223"]}],"id":[{"id":"10.13039\/501100018636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018636","name":"Xuzhou Science and Technology Program","doi-asserted-by":"publisher","award":["KC23151"],"award-info":[{"award-number":["KC23151"]}],"id":[{"id":"10.13039\/501100018636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017962","name":"Jiangsu Commission of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017962","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010854","name":"Jiangsu Provincial Health Commission","doi-asserted-by":"publisher","award":["M2021112"],"award-info":[{"award-number":["M2021112"]}],"id":[{"id":"10.13039\/501100010854","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.clinph.2025.03.021","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T01:58:24Z","timestamp":1742867904000},"page":"205-212","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Specific alterations of anterior cingulate cortex subregions in somatic depression: A resting-state fMRI study"],"prefix":"10.1016","volume":"173","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5089-6134","authenticated-orcid":false,"given":"Tingting","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7966-4400","authenticated-orcid":false,"given":"Liuyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0435-8408","authenticated-orcid":false,"given":"Chaoqi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinph.2025.03.021_b0005","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jad.2016.06.030","article-title":"The impact of somatic symptoms on the course of major depressive disorder","volume":"205","author":"Bekhuis","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.clinph.2025.03.021_b0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.tins.2020.10.007","article-title":"The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self","volume":"44","author":"Chen","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.clinph.2025.03.021_b0015","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/hbm.23843","article-title":"Reproducibility of R-fMRI metrics on the impact of different strategies for multiple comparison correction and sample sizes","volume":"39","author":"Chen","year":"2018","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.clinph.2025.03.021_b0020","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1017\/S0033291712000323","article-title":"Regionally specific alterations in functional connectivity of the anterior cingulate cortex in major depressive disorder","volume":"42","author":"Davey","year":"2012","journal-title":"Psychol. Med."},{"key":"10.1016\/j.clinph.2025.03.021_b0025","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/(SICI)1096-9861(20000529)421:2<172::AID-CNE4>3.0.CO;2-8","article-title":"Subcortical projections of area 25 (subgenual cortex) of the macaque monkey","volume":"421","author":"Freedman","year":"2000","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.clinph.2025.03.021_b0030","first-page":"1517","article-title":"Depression is the leading cause of disability around the world","volume":"317","author":"Friedrich","year":"2017","journal-title":"JAMA-J. Am. Med. Association"},{"key":"10.1016\/j.clinph.2025.03.021_b0035","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.jad.2018.12.066","article-title":"Altered regional homogeneity in patients with somatic depression: A resting-state fMRI study","volume":"246","author":"Geng","year":"2019","journal-title":"J. Affect. Disord."},{"issue":"Suppl 7","key":"10.1016\/j.clinph.2025.03.021_b0040","first-page":"5","article-title":"Physical symptoms of depression: unmet needs","volume":"64","author":"Greden","year":"2003","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.clinph.2025.03.021_b0045","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.clinph.2025.03.021_b0050","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1037\/a0038101","article-title":"Interoceptive dysfunction: toward an integrated framework for understanding somatic and affective disturbance in depression","volume":"141","author":"Harshaw","year":"2015","journal-title":"Psychol. Bull."},{"key":"10.1016\/j.clinph.2025.03.021_b0055","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1186\/s12888-023-04693-0","article-title":"Abnormal functional connectivity of the nucleus accumbens subregions mediates the association between anhedonia and major depressive disorder","volume":"23","author":"Hu","year":"2023","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.clinph.2025.03.021_b0060","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/j.1440-1819.2006.01585.x","article-title":"Depression and somatic symptoms scale: a new scale with both depression and somatic symptoms emphasized","volume":"60","author":"Hung","year":"2006","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.clinph.2025.03.021_b0065","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.scib.2019.05.008","article-title":"RESTplus: an improved toolkit for resting-state functional magnetic resonance imaging data processing","volume":"64","author":"Jia","year":"2019","journal-title":"Science Bulletin"},{"key":"10.1016\/j.clinph.2025.03.021_b0070","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.1591","article-title":"Pregenual or subgenual anterior cingulate cortex as potential effective region for brain stimulation of depression","volume":"10","author":"Jing","year":"2020","journal-title":"Brain Behavior"},{"key":"10.1016\/j.clinph.2025.03.021_b0075","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1523\/JNEUROSCI.2363-17.2017","article-title":"Cortical Connections Position Primate Area 25 as a Keystone for Interoception, Emotion, and Memory","volume":"38","author":"Joyce","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.clinph.2025.03.021_b0080","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.bpsc.2017.12.004","article-title":"Interoception and Mental Health: A Roadmap","volume":"3","author":"Khalsa","year":"2018","journal-title":"Biol. Psychiatry-Cognitive Neurosci. Neuroimaging"},{"key":"10.1016\/j.clinph.2025.03.021_b0085","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1038\/s41598-018-38078-1","article-title":"Anterior cingulate GABA and glutamate concentrations are associated with resting-state network connectivity","volume":"9","author":"Levar","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.clinph.2025.03.021_b0090","article-title":"Predictive potential of somatic symptoms for the identification of subthreshold depression and major depressive disorder in primary care settings","volume":"14","author":"Li","year":"2023","journal-title":"Front. Psych."},{"key":"10.1016\/j.clinph.2025.03.021_b0095","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jad.2020.03.107","article-title":"Brain structural and functional alterations in MDD patient with gastrointestinal symptoms: A resting-state MRI study","volume":"273","author":"Liu","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.clinph.2025.03.021_b0100","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.jad.2021.08.143","article-title":"Brain functional alterations in MDD patients with somatic symptoms: A resting-state fMRI study","volume":"295","author":"Liu","year":"2021","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.clinph.2025.03.021_b0105","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/mp.2014.68","article-title":"Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings","volume":"19","author":"Northoff","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.clinph.2025.03.021_b0110","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1093\/cercor\/bhy124","article-title":"Human Pregenual Anterior Cingulate Cortex: Structural, Functional, and Connectional Heterogeneity","volume":"29","author":"Palomero-Gallagher","year":"2019","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.clinph.2025.03.021_b0115","first-page":"3701","article-title":"Abnormal functional connectivity with mood regulating circuit in unmedicated individual with major depression: a resting-state functional magnetic resonance study","volume":"125","author":"Peng","year":"2012","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.clinph.2025.03.021_b0120","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1017\/S0033291720000434","article-title":"Sub-regional anterior cingulate cortex functional connectivity revealed default network subsystem dysfunction in patients with major depressive disorder","volume":"51","author":"Peng","year":"2021","journal-title":"Psychol. Med."},{"key":"10.1016\/j.clinph.2025.03.021_b0125","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1006\/nimg.2002.1087","article-title":"Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI","volume":"16","author":"Phan","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.clinph.2025.03.021_b0130","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/scan\/nsaa014","article-title":"Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression","volume":"15","author":"Rolls","year":"2020","journal-title":"Soc. Cogn. Affect. Neurosci."},{"key":"10.1016\/j.clinph.2025.03.021_b0135","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.1093\/cercor\/bhy236","article-title":"Functional Connectivity of the Anterior Cingulate Cortex in Depression and in Health","volume":"29","author":"Rolls","year":"2019","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.clinph.2025.03.021_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116189","article-title":"Automated anatomical labelling atlas 3","volume":"206","author":"Rolls","year":"2020","journal-title":"Neuroimage"},{"key":"10.1016\/j.clinph.2025.03.021_b0145","first-page":"875","article-title":"Major depressive disorder: mechanism-based prescribing for personalized medicine","volume":"11","author":"Saltiel","year":"2015","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.clinph.2025.03.021_b0150","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.psychres.2014.07.054","article-title":"Differences in the developmental patterns of depression with and without additional somatic symptoms","volume":"220","author":"Silverstein","year":"2014","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.clinph.2025.03.021_b0155","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1093\/brain\/awr117","article-title":"The contribution of the putamen to sensory aspects of pain: insights from structural connectivity and brain lesions","volume":"134","author":"Starr","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.clinph.2025.03.021_b0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cortex.2014.04.002","article-title":"Submodalities of emotion in the context of cingulate subregions","volume":"59","author":"Vogt","year":"2014","journal-title":"Cortex"},{"key":"10.1016\/j.clinph.2025.03.021_b0165","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jpsychires.2022.09.014","article-title":"Smaller putamen volumes are associated with greater problems in external emotional regulation in depressed adolescents with nonsuicidal self-injury","volume":"155","author":"Wang","year":"2022","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.clinph.2025.03.021_b0170","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.pnpbp.2015.07.006","article-title":"Diminished caudate and superior temporal gyrus responses to effort-based decision making in patients with first-episode major depressive disorder","volume":"64","author":"Yang","year":"2016","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.clinph.2025.03.021_b0175","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1159\/000527276","article-title":"The common neural mechanism of somatic symptoms of depression and anxiety disorders: a resting-state functional magnetic resonance imaging study","volume":"82","author":"Yu","year":"2023","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.clinph.2025.03.021_b0180","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.pnpbp.2017.02.001","article-title":"Intrinsic cerebral activity at resting state in adults with major depressive disorder: A meta-analysis","volume":"75","author":"Zhou","year":"2017","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245725004377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245725004377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:24:52Z","timestamp":1778811892000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245725004377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":36,"alternative-id":["S1388245725004377"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2025.03.021","relation":{},"ISSN":["1388-2457"],"issn-type":[{"value":"1388-2457","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Specific alterations of anterior cingulate cortex subregions in somatic depression: A resting-state fMRI study","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2025.03.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}