{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T12:00:58Z","timestamp":1784980858943,"version":"3.55.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.clinph.2026.2111845","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T17:22:35Z","timestamp":1774545755000},"page":"2111845","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Quantitative sonographic assessment of relaxed and contracted muscle thickness predicts survival in ALS"],"prefix":"10.1016","volume":"187","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4360-8916","authenticated-orcid":false,"given":"David","family":"Kravitz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9180-2708","authenticated-orcid":false,"given":"Tahani Sheikh","family":"Saker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noga","family":"Odess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian E.","family":"Drory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9020-2399","authenticated-orcid":false,"given":"Alon","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0005","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/mus.26758","article-title":"Quantitative sonographic evaluation of muscle thickness and fasciculation prevalence in healthy subjects","volume":"61","author":"Abraham","year":"2020","journal-title":"Muscle Nerve"},{"issue":"7","key":"10.1016\/j.clinph.2026.2111845_b0010","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.clinph.2020.04.003","article-title":"Superiority of sonographic evaluation of contracted versus relaxed muscle thickness in motor neuron diseases","volume":"131","author":"Abraham","year":"2020","journal-title":"Clin. Neurophysiol."},{"issue":"9","key":"10.1016\/j.clinph.2026.2111845_b0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0292123","article-title":"Quantitative sonographic assessment of muscle thickness and fasciculations distribution is a sensitive tool for neuromuscular disorders","volume":"18","author":"Abraham","year":"2023","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.clinph.2026.2111845_b0020","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1136\/jnnp.2009.200519","article-title":"Muscle ultrasonography to predict survival in amyotrophic lateral sclerosis","volume":"82","author":"Arts","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0025","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/mus.27125","article-title":"Fasciculation frequency at the biceps brachii and brachialis muscles is associated with amyotrophic lateral sclerosis disease burden and activity","volume":"63","author":"Avidan","year":"2021","journal-title":"Muscle Nerve"},{"issue":"6","key":"10.1016\/j.clinph.2026.2111845_b0030","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/WNP.0000000000000917","article-title":"The sensitivity of quantitative sonographic assessment of muscle thickness for amyotrophic lateral sclerosis diagnosis","volume":"40","author":"Avidan","year":"2023","journal-title":"J. Clin. Neurophysiol."},{"key":"10.1016\/j.clinph.2026.2111845_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2024.105323","article-title":"Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis","volume":"108","author":"Benatar","year":"2024","journal-title":"EBioMedicine"},{"issue":"5","key":"10.1016\/j.clinph.2026.2111845_b0040","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1080\/146608200300079536","article-title":"El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis","volume":"1","author":"Brooks","year":"2000","journal-title":"Amyotroph. Lateral Scler. Other Motor Neuron Disord."},{"issue":"3","key":"10.1016\/j.clinph.2026.2111845_b0045","doi-asserted-by":"crossref","DOI":"10.1002\/jcsm.13827","article-title":"Quantification of skeletal muscle at the first lumbar level for prognosis in amyotrophic lateral sclerosis","volume":"16","author":"Cao","year":"2025","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"issue":"5","key":"10.1016\/j.clinph.2026.2111845_b0050","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1002\/jcsm.13041","article-title":"The current use of ultrasound to measure skeletal muscle and its ability to predict clinical outcomes: a systematic review","volume":"13","author":"Casey","year":"2022","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"issue":"1\u20132","key":"10.1016\/j.clinph.2026.2111845_b0055","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0022-510X(99)00210-5","article-title":"The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function","volume":"169","author":"Cedarbaum","year":"1999","journal-title":"J. Neurol. Sci."},{"issue":"1","key":"10.1016\/j.clinph.2026.2111845_b0060","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1136\/jnnp-2013-306589","article-title":"Development and evaluation of a clinical staging system for amyotrophic lateral sclerosis","volume":"86","author":"Chi\u00f2","year":"2015","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"3","key":"10.1016\/j.clinph.2026.2111845_b0065","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1136\/jnnp.2005.072660","article-title":"Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population","volume":"77","author":"Czaplinski","year":"2005","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"3","key":"10.1016\/j.clinph.2026.2111845_b0070","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1002\/mus.27344","article-title":"Relative effects of forced vital capacity and ALSFRS\u2010R on survival in ALS","volume":"64","author":"Daghlas","year":"2021","journal-title":"Muscle Nerve"},{"issue":"10360","key":"10.1016\/j.clinph.2026.2111845_b0075","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0140-6736(22)01272-7","article-title":"Amyotrophic lateral sclerosis","volume":"400","author":"Feldman","year":"2022","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0080","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/(SICI)1097-4598(199702)20:2<179::AID-MUS7>3.0.CO;2-9","article-title":"A longitudinal study comparing thenar motor unit number estimates to other quantitative tests in patients with amyotrophic lateral sclerosis","volume":"20","author":"Felice","year":"1997","journal-title":"Muscle Nerve"},{"issue":"4","key":"10.1016\/j.clinph.2026.2111845_b0085","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/bimj.200410135","article-title":"Estimation of the youden index and its associated cutoff point","volume":"47","author":"Fluss","year":"2005","journal-title":"Biom. J."},{"issue":"4","key":"10.1016\/j.clinph.2026.2111845_b0090","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1001\/jamaneurol.2019.4490","article-title":"Development and validation of the rasch-built overall amyotrophic lateral sclerosis disability scale (ROADS)","volume":"77","author":"Fournier","year":"2020","journal-title":"JAMA Neurol."},{"issue":"1","key":"10.1016\/j.clinph.2026.2111845_b0095","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/ana.26933","article-title":"Sex differences in amyotrophic lateral sclerosis survival and progression: a multidimensional analysis","volume":"96","author":"Grassano","year":"2024","journal-title":"Ann. Neurol."},{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0100","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.0006-341X.2000.00337.x","article-title":"Time\u2010dependent ROC curves for censored survival data and a diagnostic marker","volume":"56","author":"Heagerty","year":"2000","journal-title":"Biometrics"},{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0105","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/mus.26487","article-title":"ultrasound in the diagnosis and monitoring of amyotrophic lateral sclerosis: a review","volume":"60","author":"Hobson-Webb","year":"2019","journal-title":"Muscle Nerve"},{"issue":"6","key":"10.1016\/j.clinph.2026.2111845_b0110","doi-asserted-by":"crossref","first-page":"542","DOI":"10.3109\/17482968.2010.482592","article-title":"A decrease in body mass index is associated with faster progression of motor symptoms and shorter survival in ALS","volume":"11","author":"Jawaid","year":"2010","journal-title":"Amyotroph. Lateral Scler."},{"issue":"8","key":"10.1016\/j.clinph.2026.2111845_b0120","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000010235","article-title":"A prospective harmonized multicenter DTI study of cerebral white matter degeneration in ALS","volume":"95","author":"Kalra","year":"2020","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.clinph.2026.2111845_b0125","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1212\/01.WNL.0000148648.38313.64","article-title":"The ALSFRSr predicts survival time in an ALS clinic population","volume":"64","author":"Kaufmann","year":"2005","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0130","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1212\/01.wnl.0000194316.91908.8a","article-title":"Progression rate of ALSFRS-R at time of diagnosis predicts survival time in ALS","volume":"66","author":"Kimura","year":"2006","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/j.clinph.2026.2111845_b0135","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1136\/jnnp-2015-312908","article-title":"A clinical tool for predicting survival in ALS","volume":"87","author":"Knibb","year":"2016","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"6","key":"10.1016\/j.clinph.2026.2111845_b0140","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1002\/ana.27196","article-title":"Regional cerebral atrophy contributes to personalized survival prediction in amyotrophic lateral sclerosis: a multicentre, machine learning, deformation\u2010based morphometry study","volume":"97","author":"Lajoie","year":"2025","journal-title":"Ann. Neurol."},{"issue":"5","key":"10.1016\/j.clinph.2026.2111845_b0145","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1002\/mus.21779","article-title":"Muscle ultrasound quantifies the rate of reduction of muscle thickness in amyotrophic lateral sclerosis","volume":"42","author":"Lee","year":"2010","journal-title":"Muscle Nerve"},{"issue":"1","key":"10.1016\/j.clinph.2026.2111845_b0150","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s00415-024-12743-0","article-title":"Incidence and mortality of ALS: a 42-year population-based nationwide study","volume":"272","author":"Levison","year":"2025","journal-title":"J. Neurol."},{"key":"10.1016\/j.clinph.2026.2111845_b0155","doi-asserted-by":"crossref","first-page":"s10","DOI":"10.1016\/S0022-510X(97)00238-4","article-title":"Amyotrophic lateral sclerosis: mortality risk during the course of the disease and prognostic factors","volume":"152","author":"Louwerse","year":"1997","journal-title":"J. Neurol. Sci."},{"issue":"11","key":"10.1016\/j.clinph.2026.2111845_b0160","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1038\/s41593-021-00936-z","article-title":"Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis","volume":"24","author":"Magen","year":"2021","journal-title":"Nat. Neurosci."},{"issue":"5","key":"10.1016\/j.clinph.2026.2111845_b0165","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/mus.10090","article-title":"Disease progression in amyotrophic lateral sclerosis: predictors of survival","volume":"25","author":"Magnus","year":"2002","journal-title":"Muscle Nerve"},{"issue":"6","key":"10.1016\/j.clinph.2026.2111845_b0170","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/j.ultrasmedbio.2017.02.002","article-title":"Muscular echovariation: a new biomarker in amyotrophic lateral sclerosis","volume":"43","author":"Mart\u00ednez-Pay\u00e1","year":"2017","journal-title":"Ultrasound Med. Biol."},{"issue":"16","key":"10.1016\/j.clinph.2026.2111845_b0175","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1212\/WNL.0b013e318233b36a","article-title":"Ultrasonographic detection of fasciculations markedly increases diagnostic sensitivity of ALS","volume":"77","author":"Misawa","year":"2011","journal-title":"Neurology"},{"issue":"10","key":"10.1016\/j.clinph.2026.2111845_b0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0141500","article-title":"Prognostic factors in amyotrophic lateral sclerosis: a population-based study","volume":"10","author":"Moura","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.clinph.2026.2111845_b0185","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/21678421.2012.735240","article-title":"Premorbid body mass index and risk of amyotrophic lateral sclerosis","volume":"14","author":"O\u2019Reilly","year":"2013","journal-title":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"},{"issue":"2","key":"10.1016\/j.clinph.2026.2111845_b0190","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/ana.24096","article-title":"Long\u2010term survival in amyotrophic lateral sclerosis: a population\u2010based study","volume":"75","author":"Pupillo","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.clinph.2026.2111845_b0195","unstructured":"Ranieri, F., et al., 2025. Cortical excitability as a prognostic and phenotypic stratification biomarker in amyotrophic lateral sclerosis, Ann. Neurol. [Preprint]. 10.1002\/ana.27305."},{"issue":"8","key":"10.1016\/j.clinph.2026.2111845_b0200","doi-asserted-by":"crossref","first-page":"4266","DOI":"10.1007\/s00330-018-5943-8","article-title":"Quantitative neuromuscular ultrasound analysis as biomarkers in amyotrophic lateral sclerosis","volume":"29","author":"R\u00edos-D\u00edaz","year":"2019","journal-title":"Eur. Radiol."},{"issue":"3","key":"10.1016\/j.clinph.2026.2111845_b0205","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/brain\/awr351","article-title":"A proposed staging system for amyotrophic lateral sclerosis","volume":"135","author":"Roche","year":"2012","journal-title":"Brain"},{"issue":"12","key":"10.1016\/j.clinph.2026.2111845_b0215","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1212\/WNL.0000000000003741","article-title":"Urinary P75: a prognostic, disease progression, and pharmacodynamic biomarker in ALS","volume":"88","author":"Shepheard","year":"2017","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.clinph.2026.2111845_b0220","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/17482968.2012.678366","article-title":"Reduction rate of body mass index predicts prognosis for survival in amyotrophic lateral sclerosis: a multicenter study in Japan","volume":"13","author":"Shimizu","year":"2012","journal-title":"Amyotroph. Lateral Scler."},{"issue":"1","key":"10.1016\/j.clinph.2026.2111845_b0225","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1212\/WNL.50.1.66","article-title":"Prognostic indicators of survival in ALS","volume":"50","author":"Stambler","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2026.2111845_b0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103732","article-title":"Predictors of survival in patients with amyotrophic lateral sclerosis: a large meta-analysis","volume":"74","author":"Su","year":"2021","journal-title":"EBioMedicine"},{"issue":"6","key":"10.1016\/j.clinph.2026.2111845_b0235","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.clinph.2017.02.015","article-title":"A muscle ultrasound score in the diagnosis of amyotrophic lateral sclerosis","volume":"128","author":"Tsuji","year":"2017","journal-title":"Clin. Neurophysiol."},{"issue":"11","key":"10.1016\/j.clinph.2026.2111845_b0240","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1080\/01616412.2022.2096004","article-title":"Temporal muscle thickness and survival in patients with amyotrophic lateral sclerosis","volume":"44","author":"Vinciguerra","year":"2022","journal-title":"Neurol. Res."},{"key":"10.1016\/j.clinph.2026.2111845_b0245","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.neuro.2016.06.015","article-title":"Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis","volume":"61","author":"Wang","year":"2017","journal-title":"Neurotoxicology"},{"issue":"5","key":"10.1016\/j.clinph.2026.2111845_b0250","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S1474-4422(18)30089-9","article-title":"Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model","volume":"17","author":"Westeneng","year":"2018","journal-title":"Lancet Neurol."},{"issue":"4","key":"10.1016\/j.clinph.2026.2111845_b0255","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/mus.28064","article-title":"Clinical prognostic factors predicting survival of motor neuron disease patients with gastrostomy: a retrospective analysis","volume":"69","author":"Yang","year":"2024","journal-title":"Muscle Nerve"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245726003445?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245726003445?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T11:27:56Z","timestamp":1784978876000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245726003445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":49,"alternative-id":["S1388245726003445"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2026.2111845","relation":{},"ISSN":["1388-2457"],"issn-type":[{"value":"1388-2457","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantitative sonographic assessment of relaxed and contracted muscle thickness predicts survival in ALS","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2026.2111845","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"2111845"}}