{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T12:01:07Z","timestamp":1784980867943,"version":"3.55.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Neurophysiology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.clinph.2026.2111865","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:45:40Z","timestamp":1774583140000},"page":"2111865","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Vagus nerve hypotrophy in genetically confirmed cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) patients"],"prefix":"10.1016","volume":"187","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8338-1280","authenticated-orcid":false,"given":"Jacopo","family":"Di Giovanni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1950-1468","authenticated-orcid":false,"given":"Gabriella","family":"Silvestri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianmarco","family":"Dalla Zanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiola","family":"Tomasello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Funcis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7102-9180","authenticated-orcid":false,"given":"Salvatore","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Merico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Madia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Granata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinph.2026.2111865_b0005","doi-asserted-by":"crossref","unstructured":"Cortese, A., Simone, R., Sullivan, R., Vandrovcova, J., Tariq, H., Yan Yau, W., et al. 2019. Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia. doi: 10.1038\/s41588-019-0372-4.Epub 2019 Mar 29.","DOI":"10.1038\/s41588-019-0422-y"},{"key":"10.1016\/j.clinph.2026.2111865_b0010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/practneurol-2020-002822","article-title":"Cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS): genetic and clinical aspects","volume":"22","author":"Cortese","year":"2022","journal-title":"Pract. Neurol."},{"issue":"9","key":"10.1016\/j.clinph.2026.2111865_b0015","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1002\/mds.30279","article-title":"Prevalence and clinical correlates of sleep disorders in RFC1-spectrum disorders: a cross-sectional study","volume":"40","author":"Funcis","year":"2025","journal-title":"Mov Disord."},{"key":"10.1016\/j.clinph.2026.2111865_b0020","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/jns.12655","article-title":"Nerve ultrasound in CANVAS-spectrum disease: Reduced nerve size distinguishes genetically confirmed CANVAS from other axonal polyneuropathies","volume":"29","author":"Salvalaggio","year":"2024","journal-title":"J. Peripher. Nerv. Syst."},{"issue":"16","key":"10.1016\/j.clinph.2026.2111865_b0025","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1212\/WNL.0000000000000352","article-title":"Dorsal root ganglionopathy is responsible for the sensory impairment in CANVAS","volume":"82","author":"Szmulewicz","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.clinph.2026.2111865_b0030","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1007\/s00415-023-12001-9","article-title":"Clinical and functional characteristics, possible causes, and impact of chronic cough in patients with CANVAS","volume":"271","author":"Palones","year":"2024","journal-title":"J. Neurol."},{"key":"10.1016\/j.clinph.2026.2111865_b0035","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.clinph.2022.07.501","article-title":"Dysautonomia in RFC1-related disorder: Clinical and neurophysiological evaluation","volume":"142","author":"da Silva Schmitt","year":"2022","journal-title":"Clin Neurophysiol."},{"key":"10.1016\/j.clinph.2026.2111865_b0040","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1183\/09031936.95.08071193","article-title":"Neurophysiology of the cough reflex","volume":"8","author":"Widdicombe","year":"1995","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.clinph.2026.2111865_b0045","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1002\/mus.25993","article-title":"Sonographic evaluation of the vagus nerves: protocol, reference values, and side\u2010to\u2010side differences","volume":"57","author":"Pelz","year":"2018","journal-title":"Muscle Nerve"},{"issue":"2","key":"10.1016\/j.clinph.2026.2111865_b0050","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/jon.12956","article-title":"Vagus nerve ultrasound in transthyretin familial amyloid polyneuropathy: a pilot study","volume":"32","author":"Du","year":"2022","journal-title":"J. Neuroimaging"},{"issue":"12","key":"10.1016\/j.clinph.2026.2111865_b0055","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1007\/s12264-023-01104-y","article-title":"Neural mechanisms underlying the coughing reflex","volume":"39","author":"Lu","year":"2023","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.clinph.2026.2111865_b0060","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/ene.13563","article-title":"Peripheral nerves are pathologically small in cerebellar ataxia neuropathy vestibular areflexia syndrome: a controlled ultrasound study","volume":"25","author":"Pelosi","year":"2018","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.clinph.2026.2111865_b0065","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/WNP.0000000000000856","article-title":"Sonographic reference values of Vagus nerve: a systematic review and meta-analysis","volume":"39","author":"Abdelnaby","year":"2022","journal-title":"J. Clin. Neurophysiol."},{"key":"10.1016\/j.clinph.2026.2111865_b0070","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1093\/brain\/awab449","article-title":"Motor neuron pathology in CANVAS due to RFC1expansions","volume":"145","author":"Huin","year":"2022","journal-title":"Brain"}],"container-title":["Clinical Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245726003640?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388245726003640?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T11:29:20Z","timestamp":1784978960000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388245726003640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":14,"alternative-id":["S1388245726003640"],"URL":"https:\/\/doi.org\/10.1016\/j.clinph.2026.2111865","relation":{},"ISSN":["1388-2457"],"issn-type":[{"value":"1388-2457","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vagus nerve hypotrophy in genetically confirmed cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) patients","name":"articletitle","label":"Article Title"},{"value":"Clinical Neurophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinph.2026.2111865","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"2111865"}}