{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T08:05:58Z","timestamp":1784880358778,"version":"3.55.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics and Research in Hepatology and Gastroenterology"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.clinre.2016.07.005","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T20:22:23Z","timestamp":1473452543000},"page":"31-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":80,"title":["Non-alcoholic fatty liver disease (NAFLD) and 10-year risk of cardiovascular diseases"],"prefix":"10.1016","volume":"41","author":[{"given":"Nima","family":"Motamed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4177-1226","authenticated-orcid":false,"given":"Behnam","family":"Rabiee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Poustchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Dehestani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholam Reza","family":"Hemasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmood Reza","family":"Khonsari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansooreh","family":"Maadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh Sima","family":"Saeedian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhad","family":"Zamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl.","key":"10.1016\/j.clinre.2016.07.005_bib0175","first-page":"S186","article-title":"Non-alcoholic fatty liver disease","volume":"17","author":"Angulo","year":"2002","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0180","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.4254\/wjh.v7.i11.1450","article-title":"Non-alcoholic fatty liver disease in 2015","volume":"7","author":"Ahmed","year":"2015","journal-title":"World J Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0185","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/aje\/kws448","article-title":"Prevalence of nonalcoholic fatty liver disease in the United States: the Third National Health and Nutrition Examination Survey, 1988-1994","volume":"178","author":"Lazo","year":"2013","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0190","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/jgh.12011","article-title":"Nonalcoholic fatty liver disease in Asia: a story of growth","volume":"28","author":"Wong","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0195","first-page":"1275","article-title":"Prevalence of Non-Alcoholic Fatty Liver Disease and Its Predictors in North of Iran","volume":"43","author":"Amirkalali","year":"2014","journal-title":"Iran J Public Health"},{"key":"10.1016\/j.clinre.2016.07.005_bib0200","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1002\/hep.26717","article-title":"Extrahepatic complications of nonalcoholic fatty liver disease","volume":"59","author":"Armstrong","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.clinre.2016.07.005_bib0205","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/nrgastro.2013.41","article-title":"Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis","volume":"10","author":"Anstee","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0210","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/eurheartj\/ehr453","article-title":"Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?","volume":"33","author":"Bhatia","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.clinre.2016.07.005_bib0215","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.arcmed.2011.08.004","article-title":"Treatment of atherogenic liver based on the pathogenesis of nonalcoholic fatty liver disease: a novel approach to reduce cardiovascular risk?","volume":"42","author":"Maurantonio","year":"2011","journal-title":"Arch Med Res"},{"key":"10.1016\/j.clinre.2016.07.005_bib0220","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJMra0912063","article-title":"Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease","volume":"363","author":"Targher","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.clinre.2016.07.005_bib0225","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1007\/s10620-012-2446-3","article-title":"Anthropometric and clinical factors associated with mortality in subjects with nonalcoholic fatty liver disease","volume":"58","author":"Otgonsuren","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.clinre.2016.07.005_bib0230","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.metabol.2012.08.005","article-title":"In patients with non-alcoholic fatty liver disease, metabolically abnormal individuals are at a higher risk for mortality while metabolically normal individuals are not","volume":"62","author":"Younossi","year":"2013","journal-title":"Metabolism"},{"key":"10.1016\/j.clinre.2016.07.005_bib0235","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/CIRCULATIONAHA.107.699579","article-title":"General cardiovascular risk profile for use in primary care: the Framingham Heart Study","volume":"117","author":"D\u2019Agostino","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.clinre.2016.07.005_bib0240","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","article-title":"Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)","volume":"285","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.clinre.2016.07.005_bib0245","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1016\/j.jacc.2013.11.005","article-title":"2013 ACC\/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"63","author":"Goff","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0250","first-page":"750","article-title":"Prevalence and risk factors of cholelithiasis in Amol city, northern Iran: a population-based study","volume":"17","author":"Zamani","year":"2014","journal-title":"Arch Iran Med"},{"key":"10.1016\/j.clinre.2016.07.005_bib0255","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/MEG.0000000000000286","article-title":"Association between liver fibrosis and coronary heart disease risk in patients with nonalcoholic fatty liver disease","volume":"27","author":"Dogan","year":"2015","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0260","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1111\/j.1478-3231.2011.02753.x","article-title":"The Framingham risk score and heart disease in nonalcoholic fatty liver disease","volume":"32","author":"Treeprasertsuk","year":"2012","journal-title":"Liver Int"},{"key":"10.1016\/j.clinre.2016.07.005_bib0265","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1002\/hep.23890","article-title":"Functional and morphological vascular changes in pediatric nonalcoholic fatty liver disease","volume":"52","author":"Pacifico","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.clinre.2016.07.005_bib0270","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1097\/HJH.0b013e32833a7de6","article-title":"Increased arterial stiffness in nonalcoholic fatty liver disease: the Cardio-GOOSE study","volume":"28","author":"Salvi","year":"2010","journal-title":"J Hypertens"},{"key":"10.1016\/j.clinre.2016.07.005_bib0275","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/hep.20781","article-title":"Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease","volume":"42","author":"Villanova","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.clinre.2016.07.005_bib0280","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1016\/j.jhep.2014.12.012","article-title":"NAFLD: a multisystem disease","volume":"62","author":"Byrne","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0285","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.atherosclerosis.2013.07.052","article-title":"A systematic review: burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; should we care?","volume":"230","author":"Oni","year":"2013","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clinre.2016.07.005_bib0290","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1186\/s12944-015-0141-z","article-title":"Research advances in the relationship between nonalcoholic fatty liver disease and atherosclerosis","volume":"14","author":"Xu","year":"2015","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.clinre.2016.07.005_bib0295","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/MEG.0b013e32835a58b1","article-title":"Evaluation of early atherosclerosis markers in patients with nonalcoholic fatty liver disease","volume":"25","author":"Kucukazman","year":"2013","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0300","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.dld.2014.09.020","article-title":"Nonalcoholic fatty liver disease: a precursor of the metabolic syndrome","volume":"47","author":"Lonardo","year":"2015","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.clinre.2016.07.005_bib0305","first-page":"CD008623","article-title":"Statins for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis","volume":"12","author":"Eslami","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.clinre.2016.07.005_bib0310","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.dld.2014.07.170","article-title":"The efficacy and safety of statins for the treatment of non-alcoholic fatty liver disease","volume":"47","author":"Pastori","year":"2015","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.clinre.2016.07.005_bib0315","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1016\/S0140-6736(10)61272-X","article-title":"Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis","volume":"376","author":"Athyros","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.clinre.2016.07.005_bib0320","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1097\/MCG.0b013e31819c392e","article-title":"A pilot study using simvastatin in the treatment of nonalcoholic steatohepatitis: A randomized placebo-controlled trial","volume":"43","author":"Nelson","year":"2009","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0325","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1111\/jgh.12665","article-title":"Single non-invasive model to diagnose non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)","volume":"29","author":"Otgonsuren","year":"2014","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.clinre.2016.07.005_bib0330","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1053\/j.gastro.2005.03.084","article-title":"Sampling variability of liver biopsy in nonalcoholic fatty liver disease","volume":"128","author":"Ratziu","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clinre.2016.07.005_bib0335","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/hep.22742","article-title":"Liver biopsy","volume":"49","author":"Rockey","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.clinre.2016.07.005_bib0340","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1055\/s-0028-1091983","article-title":"Diagnosis of nonalcoholic fatty liver disease: invasive versus noninvasive","volume":"28","author":"Wieckowska","year":"2008","journal-title":"Semin Liver Dis"}],"container-title":["Clinics and Research in Hepatology and Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210740116301048?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210740116301048?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:25:25Z","timestamp":1761895525000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210740116301048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S2210740116301048"],"URL":"https:\/\/doi.org\/10.1016\/j.clinre.2016.07.005","relation":{},"ISSN":["2210-7401"],"issn-type":[{"value":"2210-7401","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-alcoholic fatty liver disease (NAFLD) and 10-year risk of cardiovascular diseases","name":"articletitle","label":"Article Title"},{"value":"Clinics and Research in Hepatology and Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinre.2016.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}