{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:02:57Z","timestamp":1790301777992,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics and Research in Hepatology and Gastroenterology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.clinre.2020.11.014","type":"journal-article","created":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T03:05:40Z","timestamp":1616209540000},"page":"101584","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Duration from the first pale stool to portoenterostomy is prognostic in biliary atresia. Comparison with age at portoenterostomy"],"prefix":"10.1016","volume":"45","author":[{"given":"Hiroki","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momoko","family":"Ara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Koga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Go","family":"Miyano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4997-4485","authenticated-orcid":false,"given":"Manabu","family":"Okawada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Doi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0096-059X","authenticated-orcid":false,"given":"Geoffrey J.","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadaharu","family":"Okazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Urao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6675-4030","authenticated-orcid":false,"given":"Atsuyuki","family":"Yamataka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.clinre.2020.11.014_bib0005","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0022-3468(89)80580-9","article-title":"Surgical limitation for biliary atresia: indication for liver transplantation","volume":"24","author":"Kasai","year":"1989","journal-title":"J Pediatr Surg"},{"issue":"12","key":"10.1016\/j.clinre.2020.11.014_bib0010","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.jpedsurg.2010.08.032","article-title":"Impact of age at Kasai operation on short- and long-term outcomes of type III biliary atresia at a single institution","volume":"45","author":"Nio","year":"2010","journal-title":"J Pediatr Surg"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0015","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/00000658-199709000-00014","article-title":"A multivariable risk factor analysis of the portoenterostomy (Kasai) procedure for biliary atresia: twenty-five years of experience from two centers","volume":"226","author":"Altman","year":"1997","journal-title":"Ann Surg"},{"issue":"4","key":"10.1016\/j.clinre.2020.11.014_bib0020","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/MPG.0b013e318189f2d5","article-title":"Long-term outcome of children with biliary atresia who were not transplanted after the Kasai operation: &20-year experience at a children\u2019s hospital","volume":"48","author":"Shinkai","year":"2009","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"2","key":"10.1016\/j.clinre.2020.11.014_bib0025","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/01.mpg.0000189339.92891.64","article-title":"Long-term prognosis of patients with biliary atresia: a 25 year summary","volume":"42","author":"Hung","year":"2006","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0030","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1034\/j.1600-0676.2001.021003175.x","article-title":"Surgery for biliary atresia","volume":"21","author":"Ohi","year":"2001","journal-title":"Liver"},{"issue":"8","key":"10.1016\/j.clinre.2020.11.014_bib0035","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.jpedsurg.2017.08.048","article-title":"Outcomes of biliary atresia in the Nordic countries - a multicenter study of 158 patients during 2005-2016","volume":"53","author":"Pakarinen","year":"2018","journal-title":"J Pediatr Surg"},{"issue":"5","key":"10.1016\/j.clinre.2020.11.014_bib0040","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1542\/peds.2008-1949","article-title":"Impact of age at Kasai operation on its results in late childhood and adolescence: a rational basis for biliary atresia screening","volume":"123","author":"Serinet","year":"2009","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.clinre.2020.11.014_bib0045","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/SLA.0b013e3181638627","article-title":"Surgical outcome in biliary atresia: etiology affects the influence of age at surgery","volume":"247","author":"Davenport","year":"2008","journal-title":"Ann Surg"},{"issue":"10","key":"10.1016\/j.clinre.2020.11.014_bib0050","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0022-3468(03)00499-8","article-title":"The Kasai portoenterostomy for biliary atresia: a review of a 27-year experience with 81 patients","volume":"38","author":"Wildhaber","year":"2003","journal-title":"J Pediatr Surg"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0055","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/BF01658700","article-title":"Current concept of the treatment of biliary atresia","volume":"17","author":"Miyano","year":"1993","journal-title":"World J Surg"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0060","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.jpeds.2006.05.030","article-title":"The biliary atresia splenic malformation syndrome: a 28-year single-center retrospective study","volume":"149","author":"Davenport","year":"2006","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.clinre.2020.11.014_bib0065","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00383-011-3019-9","article-title":"Reappraising the portoenterostomy procedure according to sound physiologic\/anatomic principles enhances postoperative jaundice clearance in biliary atresia","volume":"28","author":"Nakamura","year":"2012","journal-title":"Pediatr Surg Int"},{"issue":"9","key":"10.1016\/j.clinre.2020.11.014_bib0070","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00383-014-3551-5","article-title":"Experience of treating biliary atresia with three types of portoenterostomy at a single institution: extended, modified Kasai, and laparoscopic modified Kasai","volume":"30","author":"Wada","year":"2014","journal-title":"Pediatr Surg Int"},{"key":"10.1016\/j.clinre.2020.11.014_bib0075","series-title":"Editors. Holcomb and ashcraft\u2019s pediatric surgery","first-page":"679","article-title":"Biliary atresia","author":"Cazares","year":"2020"},{"issue":"2","key":"10.1016\/j.clinre.2020.11.014_bib0080","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1053\/jhep.2003.50346","article-title":"A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C","volume":"38","author":"Wai","year":"2003","journal-title":"Hepatology"},{"issue":"8958","key":"10.1016\/j.clinre.2020.11.014_bib0085","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/S0140-6736(95)91013-1","article-title":"Screening for biliary atresia","volume":"345","author":"Matsui","year":"1995","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.clinre.2020.11.014_bib0090","first-page":"19","article-title":"Maternal and child health: work together and learn together for maternal and child health handbook","volume":"57","author":"Nakamura","year":"2014","journal-title":"Japan Med Assoc J"},{"issue":"12","key":"10.1016\/j.clinre.2020.11.014_bib0095","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1007\/s00383-017-4160-x","article-title":"Japanese biliary atresia registry","volume":"33","author":"Nio","year":"2017","journal-title":"Pediatr Surg Int"},{"issue":"4","key":"10.1016\/j.clinre.2020.11.014_bib0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2014.12.063","article-title":"Stool color card screening for early detection of biliary atresia and long-term native liver survival: a 19-year cohort study in Japan","volume":"166","author":"Gu","year":"2015","journal-title":"J Pediatr"},{"issue":"12","key":"10.1016\/j.clinre.2020.11.014_bib0105","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s00383-017-4175-3","article-title":"Screening for biliary atresia","volume":"33","author":"Matsui","year":"2017","journal-title":"Pediatr Surg Int"},{"issue":"6","key":"10.1016\/j.clinre.2020.11.014_bib0110","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/0168-8278(95)80226-6","article-title":"Histological grading and staging of chronic hepatitis","volume":"22","author":"Ishak","year":"1995","journal-title":"J Hepatol"},{"issue":"4","key":"10.1016\/j.clinre.2020.11.014_bib0115","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1097\/SLA.0b013e318211d7d8","article-title":"Survival with the native liver after laparoscopic versus conventional kasai portoenterostomy in infants with biliary atresia: a prospective trial","volume":"253","author":"Ure","year":"2011","journal-title":"Ann Surg"},{"issue":"2","key":"10.1016\/j.clinre.2020.11.014_bib0120","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jpedsurg.2017.11.016","article-title":"Liver transplantation for deterioration in native liver function after portoenterostomy for biliary atresia in Japan: short- versus long-term survivors","volume":"53","author":"Ochi","year":"2018","journal-title":"J Pediatr Surg"},{"issue":"1","key":"10.1016\/j.clinre.2020.11.014_bib0125","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/lt.24640","article-title":"Biliary atresia: indications and timing of liver transplantation and optimization of pretransplant care","volume":"23","author":"Sundaram","year":"2017","journal-title":"Liver Transpl"},{"issue":"2","key":"10.1016\/j.clinre.2020.11.014_bib0130","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/hep.20547","article-title":"Outcome in adulthood of biliary atresia: a study of 63 patients who survived for over 20 years with their native liver","volume":"41","author":"Lykavieris","year":"2005","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.clinre.2020.11.014_bib0135","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.jpedsurg.2003.12.014","article-title":"The outcome of the older (& or =100 days) infant with biliary atresia","volume":"39","author":"Davenport","year":"2004","journal-title":"J Pediatr Surg"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0140","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s00247-018-4319-1","article-title":"Diagnostic performance of quantitative magnetic resonance imaging biomarkers for predicting portal hypertension in children and young adults with autoimmune liver disease","volume":"49","author":"Dillman","year":"2019","journal-title":"Pediatr Radiol"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0145","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/hep4.1306","article-title":"Noninvasive evaluation of liver fibrosis and portal hypertension after successful portoenterostomy for biliary atresia","volume":"3","author":"Hukkinen","year":"2019","journal-title":"Hepatol Commun"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0150","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1002\/hep.24105","article-title":"Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: an updated meta-analysis","volume":"53","author":"Lin","year":"2011","journal-title":"Hepatology"},{"issue":"11","key":"10.1016\/j.clinre.2020.11.014_bib0155","doi-asserted-by":"crossref","first-page":"807","DOI":"10.7326\/0003-4819-158-11-201306040-00005","article-title":"Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review","volume":"158","author":"Chou","year":"2013","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.clinre.2020.11.014_bib0160","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.jpedsurg.2017.10.001","article-title":"Correlation between gamma-glutamyl transpeptidase activity and outcomes after Kasai portoenterostomy for biliary atresia","volume":"53","author":"Ihn","year":"2018","journal-title":"J Pediatr Surg"},{"issue":"4","key":"10.1016\/j.clinre.2020.11.014_bib0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.sempedsurg.2020.150943","article-title":"Predicting native liver injury and survival in biliary atresia","volume":"29","author":"Hukkinen","year":"2020","journal-title":"Semin Pediatr Surg"},{"issue":"5","key":"10.1016\/j.clinre.2020.11.014_bib0170","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.jpedsurg.2020.01.027","article-title":"The evolution of early liver biopsy findings in babies with jaundice may delay the diagnosis and treatment of biliary atresia","volume":"55","author":"Lemoine","year":"2020","journal-title":"J Pediatr Surg"},{"issue":"9702","key":"10.1016\/j.clinre.2020.11.014_bib0175","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/S0140-6736(09)60946-6","article-title":"Biliary atresia","volume":"374","author":"Hartley","year":"2009","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.clinre.2020.11.014_bib0180","first-page":"662","article-title":"Biliary atresia splenic malformation syndrome: an etiologic and prognostic subgroup","volume":"113","author":"Davenport","year":"1993","journal-title":"Surgery"}],"container-title":["Clinics and Research in Hepatology and Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210740120303508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210740120303508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:31:35Z","timestamp":1761895895000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210740120303508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S2210740120303508"],"URL":"https:\/\/doi.org\/10.1016\/j.clinre.2020.11.014","relation":{},"ISSN":["2210-7401"],"issn-type":[{"value":"2210-7401","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Duration from the first pale stool to portoenterostomy is prognostic in biliary atresia. Comparison with age at portoenterostomy","name":"articletitle","label":"Article Title"},{"value":"Clinics and Research in Hepatology and Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinre.2020.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101584"}}