{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T01:30:41Z","timestamp":1788139841512,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics and Research in Hepatology and Gastroenterology"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.clinre.2024.102468","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T13:13:53Z","timestamp":1727097233000},"page":"102468","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Associations between single and combined exposures to environmental phenols and ulcerative colitis in American adults"],"prefix":"10.1016","volume":"48","author":[{"given":"Fu","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusong","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinre.2024.102468_bib0001","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1016\/j.mayocp.2019.08.009","volume":"94","year":"2019","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.clinre.2024.102468_bib0002","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/s41572-020-0205-x","article-title":"Ulcerative colitis","volume":"6","author":"Kobayashi","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.clinre.2024.102468_bib0003","doi-asserted-by":"crossref","DOI":"10.3390\/nu11071498","article-title":"Diet in the pathogenesis and management of ulcerative colitis; a review of randomized controlled dietary interventions","volume":"11","author":"Keshteli","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.clinre.2024.102468_bib0004","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1217165","article-title":"Oxidative stress, hormones, and effects of natural antioxidants on intestinal inflammation in inflammatory bowel disease","volume":"14","author":"Sahoo","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.clinre.2024.102468_bib0005","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s00204-023-03447-x","article-title":"Excretion kinetics of 1,3-dichlorobenzene and its urinary metabolites after controlled airborne exposure in human volunteers","volume":"97","author":"Schettgen","year":"2023","journal-title":"Arch Toxicol"},{"key":"10.1016\/j.clinre.2024.102468_bib0006","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.aquatox.2019.04.007","article-title":"Pollutants released from the pulp paper industry: aquatic toxicity and their health hazards","volume":"211","author":"Singh","year":"2019","journal-title":"Aquat Toxicol"},{"key":"10.1016\/j.clinre.2024.102468_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118431","article-title":"In vivo toxicity evaluations of halophenolic disinfection byproducts in drinking water: a multi-omics analysis of toxic mechanisms","volume":"218","author":"Jiang","year":"2022","journal-title":"Water Res"},{"key":"10.1016\/j.clinre.2024.102468_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2023.119462","article-title":"Cocktail\" of environmental chemicals and early reproductive outcomes of IVF: the insight from paternal and maternal exposure","volume":"348","author":"Yang","year":"2023","journal-title":"J Environ Manage"},{"key":"10.1016\/j.clinre.2024.102468_bib0009","doi-asserted-by":"crossref","first-page":"78324","DOI":"10.1007\/s11356-023-27876-4","article-title":"Exposure to p-dichlorobenzene and prevalent endocrine-related reproductive cancers among US women","volume":"30","author":"Pridgen","year":"2023","journal-title":"Environ Sci Pollut Res Int"},{"key":"10.1016\/j.clinre.2024.102468_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115793","article-title":"The urinary level of 2,4,5-trichlorophenol was positively associated with both all-cause and cause-specific mortalities in general adult residents of United States","volume":"269","author":"Wang","year":"2024","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.clinre.2024.102468_bib0011","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijheh.2019.10.002","article-title":"Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men; 2009-2017","volume":"223","author":"Frederiksen","year":"2020","journal-title":"Int J Hyg Environ Health"},{"key":"10.1016\/j.clinre.2024.102468_bib0012","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.envpol.2017.09.073","article-title":"Biomonitoring of chlorophenols in human urine from several Asian countries, Greece and the United States","volume":"232","author":"Honda","year":"2018","journal-title":"Environ Pollut"},{"key":"10.1016\/j.clinre.2024.102468_bib0013","first-page":"217","article-title":"[Exposure characteristics and health risk assessment of 97 typical chemical pollutants in human serum]","volume":"42","author":"Zhang","year":"2024","journal-title":"Se Pu"},{"key":"10.1016\/j.clinre.2024.102468_bib0014","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.envpol.2017.06.023","article-title":"Association of urinary phenolic compounds, inflammatory bowel disease and chronic diarrheal symptoms: evidence from the National Health and Nutrition Examination Survey","volume":"229","author":"de Silva","year":"2017","journal-title":"Environ Pollut"},{"key":"10.1016\/j.clinre.2024.102468_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119356","article-title":"A review of practical statistical methods used in epidemiological studies to estimate the health effects of multi-pollutant mixture","volume":"306","author":"Yu","year":"2022","journal-title":"Environ Pollut"},{"key":"10.1016\/j.clinre.2024.102468_bib0016","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s40572-017-0122-7","article-title":"Lipid and creatinine adjustment to evaluate health effects of environmental exposures","volume":"4","author":"O'Brien","year":"2017","journal-title":"Curr Environ Health Rep"},{"key":"10.1016\/j.clinre.2024.102468_bib0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/jes.2015.8","article-title":"Challenges for environmental epidemiology research: are biomarker concentrations altered by kidney function or urine concentration adjustment?","volume":"26","author":"Weaver","year":"2016","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"10.1016\/j.clinre.2024.102468_bib0018","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1002\/sim.9255","article-title":"Bayesian kernel machine regression-causal mediation analysis","volume":"41","author":"Devick","year":"2022","journal-title":"Stat Med"},{"key":"10.1016\/j.clinre.2024.102468_bib0019","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1097\/EDE.0000000000001053","article-title":"Adjustment for urinary creatinine or serum lipids for analytes assayed in pooled specimens","volume":"30","author":"Weinberg","year":"2019","journal-title":"Epidemiology"},{"key":"10.1016\/j.clinre.2024.102468_bib0020","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12940-018-0413-y","article-title":"Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression","volume":"17","author":"Bobb","year":"2018","journal-title":"Environ Health"},{"key":"10.1016\/j.clinre.2024.102468_bib0021","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1111\/1750-3841.15653","article-title":"Occurrence and dietary exposure assessment of pentachlorophenol in livestock, poultry, and aquatic foods marketed in Guangdong Province, China: based on food monitoring data from 2015 to 2018","volume":"86","author":"Zhou","year":"2021","journal-title":"J Food Sci"},{"key":"10.1016\/j.clinre.2024.102468_bib0022","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.envint.2011.04.014","article-title":"Systematic review of pentachlorophenol occurrence in the environment and in humans in China: not a negligible health risk due to the re-emergence of schistosomiasis","volume":"42","author":"Zheng","year":"2012","journal-title":"Environ Int"},{"key":"10.1016\/j.clinre.2024.102468_bib0023","first-page":"262","article-title":"Probabilistic risk assessment of dietary exposure to pentachlorophenol in Guangzhou","volume":"40","author":"Zhang","year":"2023","journal-title":"China. Food Addit Contam Part A Chem Anal Control Expo Risk Assess"},{"key":"10.1016\/j.clinre.2024.102468_bib0024","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1001\/jama.2023.23814","article-title":"What is ulcerative colitis?","volume":"331","author":"Voelker","year":"2024","journal-title":"JAMA"},{"key":"10.1016\/j.clinre.2024.102468_bib0025","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0140-6736(23)00966-2","article-title":"Ulcerative colitis","volume":"402","author":"Le Berre","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.clinre.2024.102468_bib0026","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1289\/ehp.11081","article-title":"Pentachlorophenol and cancer risk: focusing the lens on specific chlorophenols and contaminants","volume":"116","author":"Cooper","year":"2008","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.clinre.2024.102468_bib0027","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1021\/tx500487w","article-title":"ROS-triggered signaling pathways involved in the cytotoxicity and tumor promotion effects of pentachlorophenol and tetrachlorohydroquinone","volume":"28","author":"Chen","year":"2015","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.clinre.2024.102468_bib0028","doi-asserted-by":"crossref","DOI":"10.1289\/EHP11329","article-title":"Immunotoxicity evaluation of trihalophenolic disinfection by-products in mouse and human mononuclear macrophage systems: the role of RNA epitranscriptomic modification in mammalian immunity","volume":"131","author":"Qin","year":"2023","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.clinre.2024.102468_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.138187","article-title":"Evaluation of the inhibition of chlorophenols towards human cytochrome P450 3A4 and differences among various species","volume":"724","author":"Liu","year":"2020","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.clinre.2024.102468_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2023.116401","article-title":"Assessment of the inhibition risk of chlorophenol substances on cytochrome P450 via cocktail inhibition assays","volume":"461","author":"Zhang","year":"2023","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.clinre.2024.102468_bib0031","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.chemosphere.2012.05.015","article-title":"Long-term toxicology and carcinogenicity of 2,4,6-trichlorophenol","volume":"89","author":"Huff","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.clinre.2024.102468_bib0032","doi-asserted-by":"crossref","first-page":"37598","DOI":"10.1007\/s11356-022-24802-y","article-title":"Urinary pentachlorophenol in general population of central China: reproducibility, predictors, and associations with oxidative stress biomarkers","volume":"30","author":"Sun","year":"2023","journal-title":"Environ Sci Pollut Res Int"},{"key":"10.1016\/j.clinre.2024.102468_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.113745","article-title":"Oral administration of curcumin and gallic acid alleviates pentachlorophenol-induced oxidative damage in rat intestine","volume":"176","author":"Maheshwari","year":"2023","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.clinre.2024.102468_bib0034","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0249236","article-title":"Model choice for estimating the association between exposure to chemical mixtures and health outcomes: a simulation study","volume":"16","author":"Hoskovec","year":"2021","journal-title":"PLoS ONE"},{"key":"10.1016\/j.clinre.2024.102468_bib0035","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.annepidem.2011.11.004","article-title":"Estimating the health effects of exposure to multi-pollutant mixture","volume":"22","author":"Billionnet","year":"2012","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.clinre.2024.102468_bib0036","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/biostatistics\/kxu058","article-title":"Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures","volume":"16","author":"Bobb","year":"2015","journal-title":"Biostatistics"}],"container-title":["Clinics and Research in Hepatology and Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221074012400189X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221074012400189X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T06:50:45Z","timestamp":1730530245000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221074012400189X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S221074012400189X"],"URL":"https:\/\/doi.org\/10.1016\/j.clinre.2024.102468","relation":{},"ISSN":["2210-7401"],"issn-type":[{"value":"2210-7401","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations between single and combined exposures to environmental phenols and ulcerative colitis in American adults","name":"articletitle","label":"Article Title"},{"value":"Clinics and Research in Hepatology and Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinre.2024.102468","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102468"}}