{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:45:46Z","timestamp":1775004346790,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"vor","delay-in-days":167,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018693","name":"Horizon 2020","doi-asserted-by":"publisher","award":["734548"],"award-info":[{"award-number":["734548"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88881.504727\/2020-01"],"award-info":[{"award-number":["88881.504727\/2020-01"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.clinsp.2022.100073","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T02:00:19Z","timestamp":1656295219000},"page":"100073","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Impact of SARS-CoV-2 on pregnancy and neonatal outcomes: An open prospective study of pregnant women in Brazil"],"prefix":"10.1016","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2892-438X","authenticated-orcid":false,"given":"Ursula Trovato","family":"Gomez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana Pulcineli Vieira","family":"Francisco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5251-2556","authenticated-orcid":false,"given":"Fernanda Spadotto","family":"Baptista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Augusta B.C.","family":"Gibelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Maria","family":"Ibidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werther Brunow de","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane de Freitas","family":"Paganoti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ester Cerdeira","family":"Sabino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lea Campos de Oliveira da","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9464-571X","authenticated-orcid":false,"given":"Thomas","family":"Jaenisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Mayaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6135-4844","authenticated-orcid":false,"given":"Maria de Lourdes","family":"Brizot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinsp.2022.100073_bib0001","unstructured":"World Health Organization Coronavirus (COVID-19) dashboard. Available online at: https:\/\/covid19.who.int\/ Accessed 6 August 2021."},{"issue":"4","key":"10.1016\/j.clinsp.2022.100073_bib0002","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/AOG.0000000000004320","article-title":"Adverse pregnancy outcomes among individuals with and without Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): a systematic review and meta-analysis","volume":"137","author":"Huntley","year":"2021","journal-title":"Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.clinsp.2022.100073_bib0003","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cmi.2020.10.007","article-title":"Impact of COVID-19 on maternal and neonatal outcomes: a systematic review and meta-analysis","volume":"27","author":"Di Toro","year":"2021","journal-title":"Clin. Microbiol. Infect."},{"issue":"3","key":"10.1016\/j.clinsp.2022.100073_bib0004","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1002\/ijgo.13697","article-title":"Characteristics and outcomes of COVID-19 pneumonia in pregnancy compared with infected nonpregnant women","volume":"153","author":"Vizheh","year":"2021","journal-title":"Int. J. Gynaecol. Obstet."},{"issue":"1","key":"10.1016\/j.clinsp.2022.100073_bib0005","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/ijgo.13700","article-title":"The severity of COVID-19 among pregnant women and the risk of adverse maternal outcomes","volume":"154","author":"Samadi","year":"2021","journal-title":"Int. J. Gynaecol. Obstet."},{"issue":"10","key":"10.1016\/j.clinsp.2022.100073_bib0006","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1093\/cid\/ciab104","article-title":"Impact of severe acute respiratory syndrome coronavirus 2 infection on pregnancy outcomes: a population-based study","volume":"73","author":"Crovetto","year":"2021","journal-title":"Clin. Infect. Dis."},{"issue":"4","key":"10.1016\/j.clinsp.2022.100073_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2021.100329","article-title":"Maternal and perinatal outcomes in high compared to low-risk pregnancies complicated by severe acute respiratory syndrome coronavirus 2 infection (phase 2): the world association of perinatal medicine working group on coronavirus disease 2019","volume":"3","author":"D'Antonio","year":"2021","journal-title":"Am. J. Obstet. Gynecol. MFM"},{"key":"10.1016\/j.clinsp.2022.100073_bib0008","first-page":"1","article-title":"Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile","author":"Haye","year":"2021","journal-title":"J. Matern. Fetal Neonatal Med."},{"issue":"16","key":"10.1016\/j.clinsp.2022.100073_bib0009","doi-asserted-by":"crossref","first-page":"E540","DOI":"10.1503\/cmaj.202604","article-title":"The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis","volume":"193","author":"Wei","year":"2021","journal-title":"CMAJ"},{"issue":"5","key":"10.1016\/j.clinsp.2022.100073_bib0010","doi-asserted-by":"crossref","first-page":"522.e1","DOI":"10.1016\/j.ajog.2021.05.016","article-title":"Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: national cohort study","volume":"225","author":"Gurol-Urganci","year":"2021","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"4","key":"10.1016\/j.clinsp.2022.100073_bib0011","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/AOG.0000000000004339","article-title":"Disease severity and perinatal outcomes of pregnant patients with coronavirus disease 2019 (COVID-19)","volume":"137","author":"Metz","year":"2021","journal-title":"Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.clinsp.2022.100073_bib0012","doi-asserted-by":"crossref","first-page":"e13340","DOI":"10.1111\/aji.13340","article-title":"Clinical manifestations and maternal and perinatal outcomes with COVID-19","volume":"84","author":"Li","year":"2020","journal-title":"Am. J. Reprod. Immunol."},{"issue":"3","key":"10.1016\/j.clinsp.2022.100073_bib0013","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/anae.15313","article-title":"The effect of COVID-19 on general anaesthesia rates for caesarean section. A cross-sectional analysis of six hospitals in the north-west of England","volume":"76","author":"Bhatia","year":"2021","journal-title":"Anaesthesia"},{"issue":"6","key":"10.1016\/j.clinsp.2022.100073_bib0014","doi-asserted-by":"crossref","first-page":"615.e1","DOI":"10.1016\/j.ajog.2020.12.1198","article-title":"Modest reduction in adverse birth outcomes following the COVID-19 lockdown","volume":"224","author":"Caniglia","year":"2021","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"6","key":"10.1016\/j.clinsp.2022.100073_bib0015","doi-asserted-by":"crossref","first-page":"e759","DOI":"10.1016\/S2214-109X(21)00079-6","article-title":"Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis","volume":"9","author":"Chmielewska","year":"2021","journal-title":"Lancet Glob. Health"},{"issue":"1","key":"10.1016\/j.clinsp.2022.100073_bib0016","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00404-021-06049-z","article-title":"A systematic review of pregnant women with COVID-19 and their neonates","volume":"304","author":"Mirbeyk","year":"2021","journal-title":"Arch. Gynecol. Obstet."},{"issue":"8","key":"10.1016\/j.clinsp.2022.100073_bib0017","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1002\/pd.5980","article-title":"Vertical transmission of SARS-CoV2 during pregnancy: a high-risk cohort","volume":"41","author":"Maeda","year":"2021","journal-title":"Prenat. Diagn."},{"issue":"2","key":"10.1016\/j.clinsp.2022.100073_bib0018","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research eletronic data capture (REDCap) \u2013 a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."},{"key":"10.1016\/j.clinsp.2022.100073_bib0019","unstructured":"(HCFMUSP) Hospital das Clinicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo. Guia de Manejo COVID-19. Available online https:\/\/www.hc.fm.usp.br\/index.php?option=com_content&view=article&id=1598&Itemid=754"},{"key":"10.1016\/j.clinsp.2022.100073_bib0020","doi-asserted-by":"crossref","first-page":"m3320","DOI":"10.1136\/bmj.m3320","article-title":"Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis","volume":"370","author":"Allotey","year":"2020","journal-title":"BMJ"},{"issue":"11","key":"10.1016\/j.clinsp.2022.100073_bib0021","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1111\/1471-0528.16779","article-title":"Seasonal and SARS-CoV-2 pandemic changes in the incidence of gestational diabetes","volume":"128","author":"Cauldwell","year":"2021","journal-title":"BJOG"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100073_bib0022","doi-asserted-by":"crossref","first-page":"391.e1","DOI":"10.1016\/j.ajog.2020.10.005","article-title":"Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients","volume":"224","author":"Cosma","year":"2021","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"6","key":"10.1016\/j.clinsp.2022.100073_bib0023","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/uog.23655","article-title":"Increased incidence of first-trimester miscarriage during the COVID-19 pandemic","volume":"57","author":"Sacinti","year":"2021","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.clinsp.2022.100073_bib0024","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0251123","article-title":"The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: a national cohort study using the UK Obstetric Surveillance System (UKOSS)","volume":"16","author":"Vousden","year":"2021","journal-title":"PLoS One"},{"issue":"17","key":"10.1016\/j.clinsp.2022.100073_bib0025","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1001\/jama.2020.19124","article-title":"Association of SARS-CoV-2 test status and pregnancy outcomes","volume":"324","author":"Ahlberg","year":"2020","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.clinsp.2022.100073_bib0026","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/aji.12243","article-title":"New insights into the relationship between viral infection and pregnancy complications","volume":"71","author":"Kwon","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"issue":"11","key":"10.1016\/j.clinsp.2022.100073_bib0027","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1111\/1471-0528.16339","article-title":"Pre-eclampsia-like syndrome induced by severe COVID-19: a prospective observational study","volume":"127","author":"Mendoza","year":"2020","journal-title":"BJOG"},{"issue":"1","key":"10.1016\/j.clinsp.2022.100073_bib0028","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/uog.23642","article-title":"Ultrasound and Doppler findings in pregnant women with SARS-CoV-2 infection","volume":"58","author":"Soto-Torres","year":"2021","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"4","key":"10.1016\/j.clinsp.2022.100073_bib0029","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1055\/s-0040-1721658","article-title":"A review on mode of delivery during COVID-19 between December 2019 and April 2020","volume":"38","author":"Debrabandere","year":"2021","journal-title":"Am. J. Perinatol."},{"issue":"10","key":"10.1016\/j.clinsp.2022.100073_bib0030","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1111\/aogs.14206","article-title":"COVID-19 pandemic and population-level pregnancy and neonatal outcomes: a living systematic review and meta-analysis","volume":"100","author":"Yang","year":"2021","journal-title":"Acta Obstet. Gynecol. Scand."}],"container-title":["Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593222032744?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593222032744?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:59:00Z","timestamp":1761721140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1807593222032744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":30,"alternative-id":["S1807593222032744"],"URL":"https:\/\/doi.org\/10.1016\/j.clinsp.2022.100073","relation":{},"ISSN":["1807-5932"],"issn-type":[{"value":"1807-5932","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of SARS-CoV-2 on pregnancy and neonatal outcomes: An open prospective study of pregnant women in Brazil","name":"articletitle","label":"Article Title"},{"value":"Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinsp.2022.100073","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 HCFMUSP. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"100073"}}