{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T19:41:33Z","timestamp":1788810093902,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"vor","delay-in-days":237,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006704","name":"Ostravsk\u00e1 Univerzita v Ostrav\u011b","doi-asserted-by":"publisher","award":["SGS02\/LF\/2016"],"award-info":[{"award-number":["SGS02\/LF\/2016"]}],"id":[{"id":"10.13039\/501100006704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006704","name":"Ostravsk\u00e1 Univerzita v Ostrav\u011b","doi-asserted-by":"publisher","award":["SGS16\/LF\/2017"],"award-info":[{"award-number":["SGS16\/LF\/2017"]}],"id":[{"id":"10.13039\/501100006704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006443","name":"VSB\u2013Technical University of Ostrava","doi-asserted-by":"publisher","award":["SP2021\/66"],"award-info":[{"award-number":["SP2021\/66"]}],"id":[{"id":"10.13039\/501100006443","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.clinsp.2022.100100","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T14:06:42Z","timestamp":1663596402000},"page":"100100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Evaluation of breast stiffness pathology based on breast compression during mammography: Proposal for novel breast stiffness scale classification"],"prefix":"10.1016","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0039-8672","authenticated-orcid":false,"given":"Ji\u0159\u00ed","family":"Prokop","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4826-0755","authenticated-orcid":false,"given":"Pavel","family":"Mar\u0161\u00e1lek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5217-0755","authenticated-orcid":false,"given":"Ilker","family":"Sengul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4302-9298","authenticated-orcid":false,"given":"Anton","family":"Pelik\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6492-2261","authenticated-orcid":false,"given":"Jana","family":"Janoutov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2423-6766","authenticated-orcid":false,"given":"Petr","family":"Horyl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6739-9966","authenticated-orcid":false,"given":"Jan","family":"Roman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0416-0621","authenticated-orcid":false,"given":"Demet","family":"Sengul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-9404","authenticated-orcid":false,"given":"Jos\u00e9 Maria Soares","family":"Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7261","key":"10.1016\/j.clinsp.2022.100100_bib0001","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1136\/bmj.321.7261.624","article-title":"Breast cancer-epidemiology, risk factors, and genetics","volume":"321","author":"McPherson","year":"2000","journal-title":"BMJ"},{"issue":"12","key":"10.1016\/j.clinsp.2022.100100_bib0002","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1093\/jnci\/djr138","article-title":"Tumor characteristics associated with mammographic detection of breast cancer in the Ontario breast screening program","volume":"103","author":"Kirsh","year":"2011","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100100_bib0003","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/bjc.2011.3","article-title":"Interval cancers in the NHS breast cancer screening programme in England, Wales and Northern Ireland","volume":"104","author":"Bennett","year":"2011","journal-title":"Br J Cancer"},{"issue":"2","key":"10.1016\/j.clinsp.2022.100100_bib0004","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1023\/A:1010627527026","article-title":"The effect of age and density of the breast on the sensitivity of breast cancer diagnostic by mammography and ultasonography","volume":"67","author":"Saarenmaa","year":"2001","journal-title":"Breast Cancer Res Treat"},{"issue":"2","key":"10.1016\/j.clinsp.2022.100100_bib0005","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1158\/1055-9965.EPI-04-0490","article-title":"The association of measured breast tissue characteristics with mammographic density and other risk factors for breast cancer","volume":"14","author":"Li","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"5","key":"10.1016\/j.clinsp.2022.100100_bib0006","doi-asserted-by":"crossref","first-page":"R129","DOI":"10.1186\/bcr622","article-title":"Mammographic density is related to stroma and stromal proteoglycan expression","volume":"5","author":"Alowami","year":"2003","journal-title":"Breast Cancer Res"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100100_bib0007","doi-asserted-by":"crossref","DOI":"10.3747\/co.23.2881","article-title":"Is clinical breast examination important for breast cancer detection?","volume":"23","author":"Provencher","year":"2016","journal-title":"Curr Oncol"},{"issue":"5","key":"10.1016\/j.clinsp.2022.100100_bib0008","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1007\/s10237-016-0763-8","article-title":"Biomechanical properties of breast tissue, a state-of-the-art review","volume":"15","author":"Rami\u00e3o","year":"2016","journal-title":"Biomech Model Mechanobiol"},{"issue":"3","key":"10.1016\/j.clinsp.2022.100100_bib0009","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1056\/NEJMoa062790","article-title":"Mammographic density and the risk and detection of breast cancer","volume":"356","author":"Boyd","year":"2007","journal-title":"N Engl J Med"},{"issue":"1370","key":"10.1016\/j.clinsp.2022.100100_bib0010","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1098\/rstb.1998.0250","article-title":"Tissue architecture: the ultimate regulator of epithelial function?","volume":"353","author":"Hagios","year":"1998","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"6","key":"10.1016\/j.clinsp.2022.100100_bib0011","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1158\/1055-9965.EPI-06-0034","article-title":"Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis","volume":"15","author":"McCormack","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100100_bib0012","doi-asserted-by":"crossref","first-page":"R114","DOI":"10.1186\/bcr3238","article-title":"High-throughput mammographic-density measurement: a tool for risk prediction of breast cancer","volume":"14","author":"Li","year":"2012","journal-title":"Breast Cancer Res"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100100_bib0013","doi-asserted-by":"crossref","first-page":"244","DOI":"10.6061\/clinics\/2017(04)09","article-title":"Breast cancer screening in developing countries","volume":"72","author":"da","year":"2017","journal-title":"Clinics (Sao Paulo)"},{"issue":"10","key":"10.1016\/j.clinsp.2022.100100_bib0014","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1038\/nmat4009","article-title":"Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium","volume":"13","author":"Chaudhuri","year":"2014","journal-title":"Nat Mater"},{"issue":"7","key":"10.1016\/j.clinsp.2022.100100_bib0015","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat Methods"},{"issue":"7","key":"10.1016\/j.clinsp.2022.100100_bib0016","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0100937","article-title":"Evidence that breast tissue stiffness is associated with risk of breast cancer","volume":"9","author":"Boyd","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.clinsp.2022.100100_bib0017","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1741-7015-6-11","article-title":"Collagen density promotes mammary tumor initiation and progression","volume":"6","author":"Provenzano","year":"2008","journal-title":"BMC Med"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100100_bib0018","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s10911-004-1404-x","article-title":"The tension mounts: mechanics meets morphogenesis and malignancy","volume":"9","author":"Paszek","year":"2004","journal-title":"J Mammary Gland Biol Neoplasia"},{"issue":"5","key":"10.1016\/j.clinsp.2022.100100_bib0019","first-page":"e15206","article-title":"Idiopathic granulomatous lobular mastitis: An imitation of breast carcinoma","volume":"13","author":"Aydin","year":"2021","journal-title":"Cureus"},{"issue":"2","key":"10.1016\/j.clinsp.2022.100100_bib0020","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nrc2544","article-title":"A tense situation: forcing tumour progression","author":"Butcher","year":"2009","journal-title":"Nat Rev Cancer"},{"issue":"1370","key":"10.1016\/j.clinsp.2022.100100_bib0021","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1098\/rstb.1998.0250","article-title":"Tissue architecture: the ultimate regulator of epithelial function?","volume":"353","author":"Hagios","year":"1998","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.clinsp.2022.100100_bib0022","first-page":"518","article-title":"The Society of Cells - Cancer and control of cell proliferation","author":"Howard","year":"1999","journal-title":"Oxford: Bios Scientific;"},{"issue":"1","key":"10.1016\/j.clinsp.2022.100100_bib0023","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/joim.12224","article-title":"Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine","volume":"276","author":"Feinberg","year":"2014","journal-title":"J Intern Med"},{"issue":"7","key":"10.1016\/j.clinsp.2022.100100_bib0024","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/nrc3486","article-title":"Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host","volume":"13","author":"Timp","year":"2013","journal-title":"Nat Rev Cancer"},{"issue":"4","key":"10.1016\/j.clinsp.2022.100100_bib0025","doi-asserted-by":"crossref","first-page":"259","DOI":"10.14735\/amko2016259","article-title":"Dva pohledy na v\u00fdvoj n\u00e1dor\u016f","volume":"29","author":"\u0160mardov\u00e1","year":"2016","journal-title":"Klin Onkol"},{"issue":"3","key":"10.1016\/j.clinsp.2022.100100_bib0026","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1088\/0031-9155\/57\/3\/R35","article-title":"Model-based elastography: a survey of approaches to the inverse elasticity problem","volume":"57","author":"Doyley","year":"2012","journal-title":"Phys Med Biol"},{"issue":"3","key":"10.1016\/j.clinsp.2022.100100_bib0027","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1243\/0954411991534933","article-title":"Elastography: ultrasonic estimation and imaging of the elastic properties of tissues","volume":"213","author":"Ophir","year":"1999","journal-title":"Proc Inst Mech Eng H"},{"issue":"Suppl 2","key":"10.1016\/j.clinsp.2022.100100_bib0028","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1046\/j.1524-4741.9.s2.9.x","article-title":"Breast cancer mortality in relation to clinical breast examination and breast self-examination","volume":"9","author":"Weiss","year":"2003","journal-title":"Breast"},{"issue":"19","key":"10.1016\/j.clinsp.2022.100100_bib0029","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1093\/jnci\/94.19.1445","article-title":"Randomized trial of breast self-examination in Shanghai: final results","volume":"94","author":"Thomas","year":"2002","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1016\/j.clinsp.2022.100100_bib0030","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1186\/s12955-020-01591-x","article-title":"Health-related quality of life in brest cacer patients: review of reviewa 2008 to 2018","volume":"18","author":"Mokhatri-Hesari","year":"2020","journal-title":"Health Qual Life Outcomes"},{"issue":"1","key":"10.1016\/j.clinsp.2022.100100_bib0031","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1186\/s12885-020-07521-w","article-title":"Effectiveness of clinical breast examination as a \u2018stand-alone\u2019 screening modality: an overview of systematic reviews","volume":"20","author":"Ngan","year":"2020","journal-title":"BMC Cancer"},{"issue":"10046","key":"10.1016\/j.clinsp.2022.100100_bib0032","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S0140-6736(16)30175-1","article-title":"Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents","volume":"388","author":"Collaboration","year":"2016","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.clinsp.2022.100100_bib0033","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3390\/ma14010140","article-title":"Modeling and testing of flexible structures with selected planar patterns used in biomedical applications","volume":"14","author":"Marsalek","year":"2021","journal-title":"Materials"},{"key":"10.1016\/j.clinsp.2022.100100_bib0034","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.3390\/sym12111837","article-title":"New design procedure of transtibial prosthesis bed stump using topological optimization method","volume":"12","author":"Sotola","year":"2020","journal-title":"Symmetry"}],"container-title":["Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593222033014?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593222033014?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T07:03:10Z","timestamp":1761721390000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1807593222033014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":34,"alternative-id":["S1807593222033014"],"URL":"https:\/\/doi.org\/10.1016\/j.clinsp.2022.100100","relation":{},"ISSN":["1807-5932"],"issn-type":[{"value":"1807-5932","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of breast stiffness pathology based on breast compression during mammography: Proposal for novel breast stiffness scale classification","name":"articletitle","label":"Article Title"},{"value":"Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinsp.2022.100100","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 HCFMUSP. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"100100"}}