{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T11:28:46Z","timestamp":1793964526824,"version":"4.8.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":239,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015401","name":"Shaanxi Province Key Research and Development Projects","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015401","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.clinsp.2026.101121","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:22:17Z","timestamp":1788902537000},"page":"101121","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Population-specific patterns of IgE sensitization in Northwest China"],"prefix":"10.1016","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2844-5084","authenticated-orcid":false,"given":"Jiahao","family":"Guan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zitong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajuan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zifan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.clinsp.2026.101121_bib0001","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/s41392-023-01344-4","article-title":"Pathogenesis of allergic diseases and implications for therapeutic interventions","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"1","key":"10.1016\/j.clinsp.2026.101121_bib0002","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s40413-015-0073-0","article-title":"Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. a statement of the world allergy organization","volume":"8","author":"D\u2019Amato","year":"2015","journal-title":"World Allergy Organ J"},{"issue":"2","key":"10.1016\/j.clinsp.2026.101121_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2018.11.001","article-title":"Trends and prescription patterns of traditional Chinese medicine use among subjects with allergic diseases: a nationwide population-based study","volume":"12","author":"Lin","year":"2019","journal-title":"World Allergy Organ J"},{"issue":"3","key":"10.1016\/j.clinsp.2026.101121_bib0004","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/all.15090","article-title":"The international EAACI\/GA\u00b2LEN\/EuroGuiDerm\/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria","volume":"77","author":"Zuberbier","year":"2022","journal-title":"Allergy"},{"issue":"6","key":"10.1016\/j.clinsp.2026.101121_bib0005","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1111\/all.16596","article-title":"Economic impact of allergic diseases and asthma-The HEAD pan-european registry","volume":"80","author":"Agache","year":"2025","journal-title":"Allergy"},{"issue":"17","key":"10.1016\/j.clinsp.2026.101121_bib0006","doi-asserted-by":"crossref","first-page":"2764","DOI":"10.3390\/cells11172764","article-title":"Current understanding of asthma pathogenesis and biomarkers","volume":"11","author":"Habib","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.clinsp.2026.101121_bib0007","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.3389\/fimmu.2018.02997","article-title":"Sex bias in asthma prevalence and pathogenesis","volume":"9","author":"Shah","year":"2018","journal-title":"Front Immunol."},{"issue":"5","key":"10.1016\/j.clinsp.2026.101121_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2020.100118","article-title":"The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources","volume":"13","author":"Caraballo","year":"2020","journal-title":"World Allergy Organ J"},{"issue":"10","key":"10.1016\/j.clinsp.2026.101121_bib0009","article-title":"Efficacy of biologic therapies in the management of allergic rhinitis: a systematic review","volume":"16","author":"Yamani","year":"2024","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.clinsp.2026.101121_bib0010","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.jaci.2017.02.007","article-title":"The microbiome in allergic disease: current understanding and future opportunities-2017 PRACTALL document of the american academy of allergy, asthma & immunology and the european academy of allergy and clinical immunology","volume":"139","author":"Huang","year":"2017","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.clinsp.2026.101121_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2020.100105","article-title":"IgE responses to multiple allergen components among school-aged children in a general population birth cohort in Tokyo","volume":"13","author":"Yamamoto-Hanada","year":"2020","journal-title":"World Allergy Organ J"},{"issue":"5","key":"10.1016\/j.clinsp.2026.101121_bib0012","doi-asserted-by":"crossref","first-page":"5025","DOI":"10.3390\/ijms24055025","article-title":"Current practice in pediatric cow's milk protein allergy-immunological features and beyond","volume":"24","author":"Emmert","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.clinsp.2026.101121_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2020.100491","article-title":"Recent advances in the management of nut allergy","volume":"14","author":"Midun","year":"2021","journal-title":"World Allergy Organ J"},{"issue":"5","key":"10.1016\/j.clinsp.2026.101121_bib0014","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.anai.2020.01.024","article-title":"Prevalence and natural history of tree nut allergy","volume":"124","author":"McWilliam","year":"2020","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"11","key":"10.1016\/j.clinsp.2026.101121_bib0015","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.3390\/nu10111706","article-title":"Almond allergy: an overview on prevalence, thresholds, regulations and allergen detection","volume":"10","author":"Mandalari","year":"2018","journal-title":"Nutrients"},{"issue":"9","key":"10.1016\/j.clinsp.2026.101121_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2023.100813","article-title":"Prevalence of self-reported food allergy in tunisia: general trends and probabilistic modeling","volume":"16","author":"Belmabrouk","year":"2023","journal-title":"World Allergy Organ J"},{"issue":"2","key":"10.1016\/j.clinsp.2026.101121_bib0017","doi-asserted-by":"crossref","DOI":"10.1172\/JCI141935","article-title":"Fecal microbiome and metabolome differ in healthy and food-allergic twins","volume":"131","author":"Bao","year":"2021","journal-title":"J Clin Invest"},{"issue":"4","key":"10.1016\/j.clinsp.2026.101121_bib0018","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.iac.2023.04.004","article-title":"Effect of gender and special considerations for women in mastocytosis and anaphylaxis","volume":"43","author":"Ellingwood","year":"2023","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.clinsp.2026.101121_bib0019","article-title":"Trends and research foci in immunoregulatory mechanisms of allergic rhinitis: a bibliometric analysis (2014-2024)","volume":"15","author":"Wang","year":"2024","journal-title":"Front Immunol"},{"key":"10.1016\/j.clinsp.2026.101121_bib0020","doi-asserted-by":"crossref","DOI":"10.3389\/falgy.2023.1173540","article-title":"Early inhalant allergen sensitization at component level: an analysis in atopic Dutch children","volume":"4","author":"Landzaat","year":"2023","journal-title":"Front Allergy"},{"key":"10.1016\/j.clinsp.2026.101121_bib0021","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1159\/000371669","article-title":"Food allergy in adolescence and adulthood","volume":"101","author":"Ballmer-Weber","year":"2015","journal-title":"Chem Immunol Allergy"},{"issue":"11","key":"10.1016\/j.clinsp.2026.101121_bib0022","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1111\/j.1398-9995.2008.01880.x","article-title":"Gender difference, sex hormones, and immediate type hypersensitivity reactions","volume":"63","author":"Chen","year":"2008","journal-title":"Allergy"},{"issue":"12","key":"10.1016\/j.clinsp.2026.101121_bib0023","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1111\/all.14908","article-title":"The role of allergen-specific IgE, IgG and IgA in allergic disease","volume":"76","author":"Shamji","year":"2021","journal-title":"Allergy"},{"issue":"10","key":"10.1016\/j.clinsp.2026.101121_bib0024","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/nri.2016.90","article-title":"Sex differences in immune responses","volume":"16","author":"Klein","year":"2016","journal-title":"Nat Rev Immunol"},{"issue":"157","key":"10.1016\/j.clinsp.2026.101121_bib0025","first-page":"39","article-title":"IgE-mediated food hypersensitivity disorders","author":"Gotua","year":"2008","journal-title":"Georgian Med News"},{"issue":"10","key":"10.1016\/j.clinsp.2026.101121_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2022.100704","article-title":"Allergic rhinitis in Chinese young adults from the Singapore\/Malaysia cross-sectional genetics epidemiology study (SMCGES) cohort: Prevalence, patterns, and epidemiology of allergic rhinitis","volume":"15","author":"Wong","year":"2022","journal-title":"World Allergy Organ J"},{"issue":"1","key":"10.1016\/j.clinsp.2026.101121_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.waojou.2022.100727","article-title":"Utility of biomarkers in the diagnosis and monitoring of asthmatic children","volume":"16","author":"Xepapadaki","year":"2023","journal-title":"World Allergy Organ J"},{"issue":"1","key":"10.1016\/j.clinsp.2026.101121_bib0028","article-title":"Cesarean section and the risk of allergic rhinitis in children: a systematic review and meta-analysis","volume":"13","author":"Liu","year":"2023","journal-title":"Sci Rep"},{"issue":"Suppl 86","key":"10.1016\/j.clinsp.2026.101121_bib0029","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","article-title":"Allergic rhinitis and its impact on asthma (ARIA) 2008","volume":"63","author":"Bousquet","year":"2008","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.clinsp.2026.101121_bib0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41572-020-00227-0","article-title":"Allergic rhinitis","volume":"6","author":"Bousquet","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.clinsp.2026.101121_bib0031","doi-asserted-by":"crossref","DOI":"10.1186\/1939-4551-6-21","article-title":"A global survey of changing patterns of food allergy burden in children","volume":"6","author":"Prescott","year":"2013","journal-title":"World Allergy Organ J"},{"issue":"12","key":"10.1016\/j.clinsp.2026.101121_bib0032","article-title":"Relationship between immune parameters and organ involvement in children with Henoch-Schonlein purpura","volume":"9","author":"Pan","year":"2017","journal-title":"PLoS ONE"},{"issue":"3","key":"10.1016\/j.clinsp.2026.101121_bib0033","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1046\/j.1523-1755.2001.059003823.x","article-title":"What is the difference between IgA nephropathy and Henoch-Sch\u00f6nlein purpura nephritis?","volume":"59","author":"Davin","year":"2001","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.clinsp.2026.101121_bib0034","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.jaci.2020.07.007","article-title":"Rhinitis 2020: a practice parameter update","volume":"146","author":"Dykewicz","year":"2020","journal-title":"J Allergy Clin Immunol"}],"container-title":["Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593226002486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593226002486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T11:13:53Z","timestamp":1793963633000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1807593226002486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":34,"alternative-id":["S1807593226002486"],"URL":"https:\/\/doi.org\/10.1016\/j.clinsp.2026.101121","relation":{},"ISSN":["1807-5932"],"issn-type":[{"value":"1807-5932","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Population-specific patterns of IgE sensitization in Northwest China","name":"articletitle","label":"Article Title"},{"value":"Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinsp.2026.101121","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 HCFMUSP. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"101121"}}