{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T09:21:34Z","timestamp":1766136094805,"version":"3.44.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicaltherapeutics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Therapeutics"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1016\/j.clinthera.2009.11.007","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T04:59:17Z","timestamp":1264481957000},"page":"2574-2583","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Association between previous health care use and initiation of inhaled corticosteroid and long-acting \u03b22-adrenergic agonist combination therapy among US patients with asthma"],"prefix":"10.1016","volume":"31","author":[{"given":"Christopher M.","family":"Blanchette","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Culler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Ershoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"2009","series-title":"Trends in asthma morbidity and mortality","key":"10.1016\/j.clinthera.2009.11.007_bib1"},{"key":"10.1016\/j.clinthera.2009.11.007_bib2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/02770900802503107","article-title":"Incremental direct expenditure of treating asthma in the United States","volume":"46","author":"Kamble","year":"2009","journal-title":"J Asthma."},{"key":"10.1016\/j.clinthera.2009.11.007_bib3","first-page":"12","article-title":"Asthma: An analysis of high-cost patients","volume":"20","author":"Malone","year":"2000","journal-title":"Pharm Pract Manag Q."},{"year":"2007","journal-title":"Full report","article-title":"Expert Panel Report 3: Guidelines for the diagnosis and management of asthma","key":"10.1016\/j.clinthera.2009.11.007_bib4"},{"key":"10.1016\/j.clinthera.2009.11.007_bib5","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.rmed.2006.03.001","article-title":"EXCEL: A randomised trial comparing salmeterol\/fluticasone propionate and formoterol\/budesonide combinations in adults with persistent asthma","volume":"100","author":"Dahl","year":"2006","journal-title":"Respir Med."},{"key":"10.1016\/j.clinthera.2009.11.007_bib6","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.2165\/00003495-200666170-00006","article-title":"Efficacy and safety of budesonide and formoterol in one pressurised metered-dose inhaler in adults and adolescents with moderate to severe asthma: A randomised clinical trial [published correction appears in Drugs. 2007;67:759]","volume":"66","author":"Noonan","year":"2006","journal-title":"Drugs"},{"key":"10.1016\/j.clinthera.2009.11.007_bib7","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1185\/030079907X210769","article-title":"Budesonide\/ formoterol maintenance and reliever therapy: A new treatment approach for adult patients with asthma","volume":"23","author":"Buhl","year":"2007","journal-title":"Curr Med Res Opin."},{"key":"10.1016\/j.clinthera.2009.11.007_bib8","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1378\/chest.129.1.15","article-title":"The Salmeterol Multicenter Asthma Research Trial: A comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol [published correction appears in Chest. 2006;129:1393]","volume":"129","author":"Nelson","year":"2006","journal-title":"Chest."},{"key":"10.1016\/j.clinthera.2009.11.007_bib9","doi-asserted-by":"crossref","first-page":"904","DOI":"10.7326\/0003-4819-144-12-200606200-00126","article-title":"Meta-analysis: Effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths","volume":"144","author":"Salpeter","year":"2006","journal-title":"Ann Intern Med."},{"year":"2009","series-title":"Symbicort inhalation aerosol [package insert]","key":"10.1016\/j.clinthera.2009.11.007_bib11"},{"year":"2009","series-title":"Advair Diskus [package insert]","key":"10.1016\/j.clinthera.2009.11.007_bib12"},{"key":"10.1016\/j.clinthera.2009.11.007_bib13","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1016\/j.clinthera.2008.10.002","article-title":"A retrospective study of the use of fluticasone propionate\/salmeterol combination as initial asthma controller therapy in a commercially insured population","volume":"30","author":"Friedman","year":"2008","journal-title":"Clin Ther."},{"key":"10.1016\/j.clinthera.2009.11.007_bib14","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1185\/03007990903155915","article-title":"Appropriate use of inhaled corticosteroid and long-acting beta(2)-adrenergic agonist combination among asthma patients in a US commercially insured population","volume":"25","author":"Ye","year":"2009","journal-title":"Curr Med Res Opin."},{"key":"10.1016\/j.clinthera.2009.11.007_bib15","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1378\/chest.130.1.8","article-title":"Followup after an asthma hospitalization: Who can prevent subsequent exacerbations?","volume":"130","author":"Schatz","year":"2006","journal-title":"Chest."},{"key":"10.1016\/j.clinthera.2009.11.007_bib16","first-page":"478","article-title":"Development and validation of a medication intensity scale derived from computerized pharmacy data that predicts emergency hospital utilization for persistent asthma","volume":"12","author":"Schatz","year":"2006","journal-title":"Am J Manag Care."},{"key":"10.1016\/j.clinthera.2009.11.007_bib17","first-page":"25","article-title":"Asthma population management: Development and validation of a practical 3-level risk stratification scheme","volume":"10","author":"Schatz","year":"2004","journal-title":"Am J Manag Care."},{"key":"10.1016\/j.clinthera.2009.11.007_bib18","first-page":"538","article-title":"Risk factors for asthma hospitalizations in a managed care organization: Development of a clinical prediction rule","volume":"9","author":"Schatz","year":"2003","journal-title":"Am J Manag Care."},{"key":"10.1016\/j.clinthera.2009.11.007_bib19","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1136\/thorax.55.7.566","article-title":"Factors associated with hospital admissions and repeat emergency department visits for adults with asthma","volume":"55","author":"Adams","year":"2000","journal-title":"Thorax."},{"key":"10.1016\/j.clinthera.2009.11.007_bib20","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S0736-4679(99)00122-5","article-title":"The identification of high risk asthmatic children using the emergency department asthma visit count","volume":"17","author":"Taylor","year":"1999","journal-title":"J Emerg Med."},{"key":"10.1016\/j.clinthera.2009.11.007_bib21","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1136\/thx.50.5.520","article-title":"Risk factors for recurrent emergency department visits for asthma","volume":"50","author":"Dales","year":"1995","journal-title":"Thorax."},{"key":"10.1016\/j.clinthera.2009.11.007_bib22","first-page":"625","article-title":"Double trouble: Impact of inappropriate use of asthma medication on the use of health care resources","volume":"164","author":"Anis","year":"2001","journal-title":"CMAJ."},{"key":"10.1016\/j.clinthera.2009.11.007_bib23","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1378\/chest.128.4.1968","article-title":"Asthma quality-of-care markers using administrative data","volume":"128","author":"Schatz","year":"2005","journal-title":"Chest."},{"key":"10.1016\/j.clinthera.2009.11.007_bib24","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1047-2797(03)00240-0","article-title":"Trends in use of inhaled corticosteroids for asthma management: 1994\u20131998","volume":"14","author":"Allen-Ramey","year":"2004","journal-title":"Ann Epidemiol."},{"key":"10.1016\/j.clinthera.2009.11.007_bib25","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.amjmed.2006.03.007","article-title":"Exploring the generalist-subspecialist interface in internal medicine","volume":"119","author":"Linzer","year":"2006","journal-title":"Am J Med."},{"key":"10.1016\/j.clinthera.2009.11.007_bib26","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1001\/archinte.161.21.2554","article-title":"Quality of care and outcomes of adults with asthma treated by specialists and generalists in managed care","volume":"161","author":"Wu","year":"2001","journal-title":"Arch Intern Med."},{"key":"10.1016\/j.clinthera.2009.11.007_bib27","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S1081-1206(10)60445-0","article-title":"Physician adherence to the national asthma prescribing guidelines: Evidence from national outpatient survey data in the United States","volume":"100","author":"Navaratnam","year":"2008","journal-title":"Ann Allergy Asthma Immunol."}],"container-title":["Clinical Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014929180900397X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014929180900397X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T08:48:26Z","timestamp":1758962906000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014929180900397X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["S014929180900397X"],"URL":"https:\/\/doi.org\/10.1016\/j.clinthera.2009.11.007","relation":{},"ISSN":["0149-2918"],"issn-type":[{"type":"print","value":"0149-2918"}],"subject":[],"published":{"date-parts":[[2009,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between previous health care use and initiation of inhaled corticosteroid and long-acting \u03b22-adrenergic agonist combination therapy among US patients with asthma","name":"articletitle","label":"Article Title"},{"value":"Clinical Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clinthera.2009.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Excerpta Medica Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}