{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T18:38:59Z","timestamp":1715711939901},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Therapeutics"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.clinthera.2010.06.001","type":"journal-article","created":{"date-parts":[[2010,7,16]],"date-time":"2010-07-16T04:53:18Z","timestamp":1279255998000},"page":"1001-1014","source":"Crossref","is-referenced-by-count":9,"title":["Review of the efficacy and tolerability of the diclofenac epolamine topical patch 1.3% in patients with acute pain due to soft tissue injuries"],"prefix":"10.1016","volume":"32","author":[{"given":"Kerry S.","family":"Kuehl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinthera.2010.06.001_bib1","first-page":"1","article-title":"Injury episodes and circumstances: National Health Interview Survey, 1997\u20132007","volume":"10","author":"Chen","year":"2009","journal-title":"Vital Health Stat"},{"key":"10.1016\/j.clinthera.2010.06.001_bib2","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1249\/00005768-199008000-00003","article-title":"Muscle strain injuries: Clinical and basic aspects","volume":"22","author":"Garrett","year":"1990","journal-title":"Med Sci Sports Exerc."},{"key":"10.1016\/j.clinthera.2010.06.001_bib3","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/00002281-199903000-00009","article-title":"Ankle sprains and other soft tissue injuries","volume":"11","author":"Liu","year":"1999","journal-title":"Curr Opin Rheumatol."},{"key":"10.1016\/j.clinthera.2010.06.001_bib4","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2165\/00007256-199928060-00001","article-title":"Anti-inflammatory treatment of muscular injuries in sport. An update of recent studies","volume":"28","author":"Almekinders","year":"1999","journal-title":"Sports Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib5","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1177\/036354659702500419","article-title":"A randomized controlled trial of piroxicam in the management of acute ankle sprain in Australian Regular Army recruits. The Kapooka Ankle Sprain Study","volume":"25","author":"Slatyer","year":"1997","journal-title":"Am J Sports Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/00042752-200407000-00005","article-title":"Efficacy of cele-coxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: Results of a doubleblind, randomized controlled trial","volume":"14","author":"Petrella","year":"2004","journal-title":"Clin J Sport Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib7","first-page":"537","article-title":"A group randomized trial to improve safe use of nonsteroidal anti-inflammatory drugs","volume":"11","author":"Curtis","year":"2005","journal-title":"Am J Manag Care."},{"key":"10.1016\/j.clinthera.2010.06.001_bib8","doi-asserted-by":"crossref","first-page":"b2538","DOI":"10.1136\/bmj.b2538","article-title":"Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis","volume":"339","author":"Latimer","year":"2009","journal-title":"BMJ."},{"key":"10.1016\/j.clinthera.2010.06.001_bib9","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1471-2474-7-79","article-title":"Nonsteroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: Review of clinical trials and clinical practice","volume":"7","author":"Moore","year":"2006","journal-title":"BMC Musculoskelet Disord."},{"key":"10.1016\/j.clinthera.2010.06.001_bib10_1","doi-asserted-by":"crossref","first-page":"65S","DOI":"10.1016\/S0002-9343(99)00369-1","article-title":"Effects of nonsteroidal anti-inflammatory drugs on renal function: Focus on cyclooxygenase-2-selective inhibition","volume":"107","author":"Brater","year":"1999","journal-title":"Am J Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib10_2","doi-asserted-by":"crossref","first-page":"70S","DOI":"10.1016\/S0002-9343(99)00369-1","article-title":"Effects of nonsteroidal anti-inflammatory drugs on renal function: Focus on cyclooxygenase-2-selective inhibition","volume":"107","author":"Brater","year":"1999","journal-title":"Am J Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib11","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1001\/jama.286.8.954","article-title":"Risk of cardiovascular events associated with selective COX-2 inhibitors","volume":"286","author":"Mukherjee","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.clinthera.2010.06.001_bib12","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0885-3924(00)00125-1","article-title":"Topical diclofenac patch relieves minor sports injury pain: Results of a multicenter controlled clinical trial","volume":"19","author":"Galer","year":"2000","journal-title":"J Pain Symptom Manage."},{"key":"10.1016\/j.clinthera.2010.06.001_bib13","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.jpainsymman.2006.11.005","article-title":"Topical agents for the management of muscu-loskeletal pain","volume":"33","author":"Stanos","year":"2007","journal-title":"J Pain Symptom Manage."},{"key":"10.1016\/j.clinthera.2010.06.001_bib14","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1136\/bmj.316.7128.333","article-title":"Quantitative systematic review of topically applied non-steroidal antiinflammatory drugs [published correction appears in BMJ. 1998;316:1059]","volume":"316","author":"Moore","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.clinthera.2010.06.001_bib15","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1055\/s-2007-1024825","article-title":"Topical indomethacin in overuse injuries in athletes. A randomized double-blind study comparing Elmetacin with oral indomethacin and placebo","volume":"11","author":"Akermark","year":"1990","journal-title":"Int J Sports Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib16","first-page":"198","article-title":"Reducing the dose of oral NSAIDs by use of Feldene Gel: An open study in elderly patients with osteoarthritis","volume":"11","author":"Browning","year":"1994","journal-title":"Adv Ther."},{"key":"10.1016\/j.clinthera.2010.06.001_bib17","first-page":"524","article-title":"A double-blind comparison of orally ingested aspirin and a topically applied salicylate cream in the relief of rheumatic pain","volume":"24","author":"Golden","year":"1978","journal-title":"Curr Ther Res Clin Exp"},{"key":"10.1016\/j.clinthera.2010.06.001_bib18","first-page":"5","article-title":"The topical NSAID felbinac versus oral ibuprofen: A comparison of efficacy in the treatment of acute lower back injury","volume":"4","author":"Hosie","year":"1993","journal-title":"Br J Clin Res."},{"key":"10.1016\/j.clinthera.2010.06.001_bib19","first-page":"139","article-title":"Study on the effect of etofenamate 10% cream in comparison with an oral NSAID in strains and sprains due to sports injuries","volume":"13","author":"Vanderstraeten","year":"1990","journal-title":"Acta Belg Med Phys."},{"key":"10.1016\/j.clinthera.2010.06.001_bib20","first-page":"567","article-title":"Pennsaid therapy for osteoarthritis of the knee: A systematic review and metaanalysis of randomized controlled trials","volume":"33","author":"Towheed","year":"2006","journal-title":"J Rheumatol."},{"key":"10.1016\/j.clinthera.2010.06.001_bib21","first-page":"2002","article-title":"Equivalence study of a topical diclofenac solution (Pennsaid) compared with oral diclofenac in symptomatic treatment of osteoarthritis of the knee: A randomized controlled trial","volume":"31","author":"Tugwell","year":"2004","journal-title":"J Rheumatol."},{"key":"10.1016\/j.clinthera.2010.06.001_bib22","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1185\/030079908X273066","article-title":"Topical diclofenac and its role in pain and inflammation: An evidence-based review","volume":"24","author":"Zacher","year":"2008","journal-title":"Curr Med Res Opin."},{"key":"10.1016\/j.clinthera.2010.06.001_bib23","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1136\/bmj.311.6996.22","article-title":"Topical non-steroidal anti-inflammatory drugs and admission to hospital for upper gastrointestinal bleeding and perforation: A record linkage case-control study","volume":"311","author":"Evans","year":"1995","journal-title":"BMJ."},{"key":"10.1016\/j.clinthera.2010.06.001_bib25","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0002-9343(86)90083-5","article-title":"Use of diclofenac in analgesia","volume":"80","author":"Kantor","year":"1986","journal-title":"Am J Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib26","first-page":"204","article-title":"Research and development of a pharmaceutical technique allowing for improvement in clinical efficacy and simplicity of use of known drugs","volume":"61","author":"Rovati","year":"2000","journal-title":"Tribuna Medi Ticinese."},{"key":"10.1016\/j.clinthera.2010.06.001_bib27","first-page":"89","article-title":"Local tolerability and pharmaco-kinetic profile of a new transdermal delivery system, diclofenac hydroxy-ethylpyrrolidine plaster","volume":"19","author":"Assandri","year":"1993","journal-title":"Drugs Exp Clin Res."},{"key":"10.1016\/j.clinthera.2010.06.001_bib28","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0378-5173(99)00180-5","article-title":"Formation of ion-pairs in aqueous solutions of diclofenac salts","volume":"187","author":"Fini","year":"1999","journal-title":"Int J Pharm."},{"key":"10.1016\/j.clinthera.2010.06.001_bib29","first-page":"81","article-title":"Diclofenac\/N-(2-hydroxyethyl)pyrrolidine: A new salt for an old drug","volume":"19","author":"Fini","year":"1993","journal-title":"Drugs Exp Clin Res."},{"key":"10.1016\/j.clinthera.2010.06.001_bib30","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1185\/03007990802381364","article-title":"Review of the pharmaceutical properties and clinical effects of the topical NSAID formulation, diclofenac epolamine","volume":"24","author":"Rainsford","year":"2008","journal-title":"Curr Med Res Opin."},{"key":"10.1016\/j.clinthera.2010.06.001_bib31","first-page":"201","article-title":"Chemical properties-dissolution relationship. IV. Behaviour in solution of the diclofenac\/N-(2-hydroxyethyl) pyrrolidine salt (DHEP)","volume":"66","author":"Fini","year":"1991","journal-title":"Pharm Acta Helv."},{"key":"10.1016\/j.clinthera.2010.06.001_bib32","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1503\/cmaj.1031793","article-title":"Effect of a topical diclofenac solution for relieving symptoms of primary osteoarthritis of the knee: A randomized controlled trial","volume":"171","author":"Bookman","year":"2004","journal-title":"CMAJ."},{"key":"10.1016\/j.clinthera.2010.06.001_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/0044011-200929010-00001","article-title":"Diclofenac epolamine (Flector) patch: Evidence for topical activity","volume":"29","author":"Petersen","year":"2009","journal-title":"Clin Drug Investig."},{"key":"10.1016\/j.clinthera.2010.06.001_bib34","first-page":"285","article-title":"Multicenter, double-blind, controlled clinical study of diclofenac Tissugel plaster in patients with epicondylitis","volume":"50","author":"Jenoure","year":"1997","journal-title":"Med Sport (Roma)."},{"key":"10.1016\/j.clinthera.2010.06.001_bib35","first-page":"1","article-title":"Study comparing the efficacy and tolerability of Flector Tissugel to that of a placebo in the treatment of benign ankle sprain","volume":"72","author":"Saillant","year":"1998","journal-title":"Sports Med."},{"key":"10.1016\/j.clinthera.2010.06.001_bib36","article-title":"Flector Tissugel in the treatment of painful ankle sprain","volume":"20","author":"Joussellin","year":"2003","journal-title":"J Traumatol Sport."},{"key":"10.1016\/j.clinthera.2010.06.001_bib37","article-title":"Flector Tissugel: Efficacy and safety in the treatment of minor sports injuries. Data from a controlled trial in the United States","volume":"20","author":"Rowbotham","year":"2003","journal-title":"J Traumatol Sport."},{"key":"10.1016\/j.clinthera.2010.06.001_bib38","series-title":"Presented at: American Pain Society 27th Annual Scientific Meeting","article-title":"Efficacy and tolerability of Flector Patch (diclofenac epolamine topical patch) in the treatment of minor soft tissue injury pain","author":"Carr","year":"2008"},{"key":"10.1016\/j.clinthera.2010.06.001_bib39","first-page":"99","article-title":"A controlled clinical study on the new topical dosage form of DHEP plasters in patients suffering from localized inflammatory diseases","volume":"19","author":"Rosenthal","year":"1993","journal-title":"Drugs Exp Clin Res."},{"key":"10.1016\/j.clinthera.2010.06.001_bib40","first-page":"125","article-title":"A trial with diclofenac HEP plaster as topical treatment in minor sport injuries","volume":"19","author":"Jenoure","year":"1993","journal-title":"Drugs Exp Clin Res."},{"key":"10.1016\/j.clinthera.2010.06.001_bib41","series-title":"Presented at: International Association for the Study of Pain (IASP) 12th World Congress on Pain","article-title":"Safety of diclofenac epolamine topical patch 1.3% evaluated in clinical trials and postmarketing surveillance","author":"Yanchick","year":"2008"},{"key":"10.1016\/j.clinthera.2010.06.001_bib42","series-title":"Presented at: The American Geriatrics Society 2009 Annual Scientific Meeting","article-title":"The safety profile of diclofenac epolamine 1.3% topical patch in elderly and non-elderly patients: Pooled analysis of 10 studies","author":"Fuller","year":"2009"},{"key":"10.1016\/j.clinthera.2010.06.001_bib43","first-page":"275","article-title":"Minor sports injuries in children: A new, safe, topical preparation containing DHEP (diclofenac epolamine)","volume":"53","author":"Polieri","year":"2000","journal-title":"Med Sport."}],"container-title":["Clinical Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014929181000192X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014929181000192X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T00:09:38Z","timestamp":1559261378000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014929181000192X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S014929181000192X"],"URL":"https:\/\/doi.org\/10.1016\/j.clinthera.2010.06.001","relation":{},"ISSN":["0149-2918"],"issn-type":[{"value":"0149-2918","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}