{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:36:03Z","timestamp":1792506963913,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Therapeutics"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.clinthera.2011.11.023","type":"journal-article","created":{"date-parts":[[2011,12,11]],"date-time":"2011-12-11T15:35:15Z","timestamp":1323617715000},"page":"124-137","source":"Crossref","is-referenced-by-count":88,"title":["Antimicrobial Susceptibility Among Gram-Negative Isolates Collected From Intensive Care Units in North America, Europe, the Asia-Pacific Rim, Latin America, the Middle East, and Africa Between 2004 and 2009 as Part of the Tigecycline Evaluation and Surveillance Trial"],"prefix":"10.1016","volume":"34","author":[{"given":"Xavier","family":"Bertrand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Dowzicky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.clinthera.2011.11.023_bib1","doi-asserted-by":"crossref","first-page":"i29","DOI":"10.1093\/jac\/dkp255","article-title":"Has the era of untreatable infections arrived?","volume":"64","author":"Livermore","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.clinthera.2011.11.023_bib2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jhin.2009.02.021","article-title":"Extended-spectrum \u03b2-lactamase-producing organisms","volume":"73","author":"Falagas","year":"2009","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.clinthera.2011.11.023_bib3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1086\/653120","article-title":"Treatment of Acinetobacter infections","volume":"51","author":"Fishbain","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.clinthera.2011.11.023_bib4","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1097\/CCM.0b013e31819ced02","article-title":"Review of studies of the impact on Gram-negative bacterial resistance on outcomes in the intensive care unit","volume":"37","author":"Shorr","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.clinthera.2011.11.023_bib5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1179\/joc.2009.21.1.16","article-title":"Antimicrobial susceptibility among bacterial isolates from ICU and non-ICU setting and different age groups: results from the Tigecycline Evaluation and Surveillance Trial in North America","volume":"21","author":"Low","year":"2009","journal-title":"J Chemother"},{"key":"10.1016\/j.clinthera.2011.11.023_bib6","series-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard","year":"2009"},{"key":"10.1016\/j.clinthera.2011.11.023_bib7","series-title":"Performance Standards for Antimicrobial Susceptibility Testing","year":"2010"},{"key":"10.1016\/j.clinthera.2011.11.023_bib8","series-title":"Performance Standards for Antimicrobial Susceptibility Testing","year":"2010"},{"key":"10.1016\/j.clinthera.2011.11.023_bib10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.diagmicrobio.2006.05.009","article-title":"Contemporary causes of skin and soft tissue infections in North America, Latin America, and Europe: report from the SENTRY antimicrobial surveillance program (1998-2004)","volume":"57","author":"Moet","year":"2007","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.clinthera.2011.11.023_bib11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/jac\/dkl199","article-title":"In vitro susceptibilities of aerobic and facultatively anaerobic Gram-negative bacilli isolates from patients with intra-abdominal infections worldwide: 2004 results from SMART (Study for Monitoring Antimicrobial Resistance Trends)","volume":"58","author":"Rossi","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.clinthera.2011.11.023_bib12","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.jinf.2010.03.024","article-title":"The in vitro evaluation of tigecycline tested against pathogens isolated in eight countries in the Asia-Western Pacific region (2008)","volume":"60","author":"Farrell","year":"2010","journal-title":"J Infect"},{"key":"10.1016\/j.clinthera.2011.11.023_bib13","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.ijantimicag.2010.09.001","article-title":"Surveillance of antimicrobial susceptibility of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections in China: the 2002\u20132009 Study for Monitoring Antimicrobial Resistance Trends (SMART)","volume":"36","author":"Yang","year":"2010","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.clinthera.2011.11.023_bib14","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.diagmicrobio.2010.10.020","article-title":"Tigecycline activity tested against multidrug-resistant Enterobacteriaceae and Acinetobacter spp. isolated in US medical centers (2005\u20132009)","volume":"69","author":"Sader","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.clinthera.2011.11.023_bib15","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.ijantimicag.2009.06.021","article-title":"Minocycline\u2014an old drug for a new century: emphasis on methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii","volume":"34","author":"Bishburg","year":"2009","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.clinthera.2011.11.023_bib16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/jac\/dkn165","article-title":"Tigecycline for the treatment of multidrug-resistant (including carbapenem-resistant) Acinetobacter infections: a review of the scientific evidence","volume":"62","author":"Karageorgopoulos","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.clinthera.2011.11.023_bib17","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1093\/jac\/dkn555","article-title":"A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline","volume":"63","author":"Gordon","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.clinthera.2011.11.023_bib18","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.diagmicrobio.2009.06.022","article-title":"Antipseudomonal activity of piperacillin\/tazobactam: more than a decade of experience from the SENTRY Antimicrobial Surveillance Program (1997\u20132007)","volume":"65","author":"Jones","year":"2009","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.clinthera.2011.11.023_bib19","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1128\/AAC.49.4.1636-1638.2005","article-title":"Presence of tetracycline resistance determinants and susceptibility to tigecycline and minocycline","volume":"49","author":"Fluit","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.clinthera.2011.11.023_bib20","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1086\/432940","article-title":"Association between fluoroquinolone resistance and mortality in Escherichia coli and Klebsiella pneumoniae infections: the role of inadequate empirical antimicrobial therapy","volume":"41","author":"Lautenbach","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.clinthera.2011.11.023_bib21","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.ijantimicag.2010.07.002","volume":"36","author":"Hsueh","year":"2010","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.clinthera.2011.11.023_bib22","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.diagmicrobio.2010.07.003","article-title":"Comprehensive assessment of tigecycline activity tested against a worldwide collection of Acinetobacter spp. (2005\u20132009)","volume":"68","author":"Mendes","year":"2010","journal-title":"Diagn Microbiol Infect Dis"}],"container-title":["Clinical Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149291811007752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149291811007752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T23:52:16Z","timestamp":1543362736000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149291811007752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S0149291811007752"],"URL":"https:\/\/doi.org\/10.1016\/j.clinthera.2011.11.023","relation":{},"ISSN":["0149-2918"],"issn-type":[{"value":"0149-2918","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}