{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:06:06Z","timestamp":1758816366621},"reference-count":23,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Therapeutics"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.clinthera.2014.06.009","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T21:00:42Z","timestamp":1404334842000},"page":"1211-1222","source":"Crossref","is-referenced-by-count":22,"title":["Comparison of the Lipid-Lowering Effects of Pitavastatin 4 mg Versus Pravastatin 40 mg in Adults With Primary Hyperlipidemia or Mixed (Combined) Dyslipidemia: A Phase IV, Prospective, US, Multicenter, Randomized, Double-blind, Superiority Trial"],"prefix":"10.1016","volume":"36","clinical-trial-number":[{"clinical-trial-number":"nct01256476","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Craig A.","family":"Sponseller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger E.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir A.","family":"Kryzhanovski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart E.","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H.","family":"Davidson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clinthera.2014.06.009_bib1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2147\/VHRM.S23113","article-title":"Lipid-lowering therapy: who can benefit?","volume":"7","author":"Lewis","year":"2011","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.clinthera.2014.06.009_bib2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1161\/01.CIR.0000133317.49796.0E","article-title":"Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines [Published correction appears in Circulation. 2004;110:763]","volume":"110","author":"Grundy","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.clinthera.2014.06.009_bib3","series-title":"Prevalence of uncontrolled risk factors for cardiovascular disease: United States, 1999\u20132010. NCHS data brief, no 103","author":"Fryar","year":"2012"},{"key":"10.1016\/j.clinthera.2014.06.009_bib4","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","article-title":"Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report","volume":"106","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.clinthera.2014.06.009_bib5","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1161\/CIRCULATIONAHA.105.169180","article-title":"Managing abnormal blood lipids: a collaborative approach","volume":"112","author":"Fletcher","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.clinthera.2014.06.009_bib6","first-page":"551","article-title":"Pharmacologic treatment of hyperlipidemia","volume":"84","author":"Last","year":"2011","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.clinthera.2014.06.009_bib7","first-page":"w13515","article-title":"Statins: have we found the Holy Grail?","volume":"142","author":"Jeger","year":"2012","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.clinthera.2014.06.009_bib8","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/CRD.0b013e3181ebdb2f","article-title":"Pitavastatin: a new HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia","volume":"18","author":"Ahmad","year":"2010","journal-title":"Cardiol Rev"},{"key":"10.1016\/j.clinthera.2014.06.009_bib9","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1021\/tx700079z","article-title":"Cytochrome P450 and chemical toxicology","volume":"21","author":"Guengerich","year":"2008","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.clinthera.2014.06.009_bib10","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1185\/03007995.2011.589433","article-title":"Drug-drug interactions with statins: will pitavastatin overcome the statins\u2019 Achilles\u2019 heel?","volume":"27","author":"Corsini","year":"2011","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.clinthera.2014.06.009_bib11","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2174\/157016112799305021","article-title":"Statin-induced myotoxicity: pharmacokinetic differences among statins and the risk of rhabdomyolysis, with particular reference to pitavastatin","volume":"10","author":"Catapano","year":"2012","journal-title":"Curr Vasc Pharmacol"},{"key":"10.1016\/j.clinthera.2014.06.009_bib12","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2165\/11207180-000000000-00000","article-title":"Pitavastatin: a review of its use in the management of hypercholesterolaemia or mixed dyslipidaemia","volume":"72","author":"Duggan","year":"2012","journal-title":"Drugs"},{"key":"10.1016\/j.clinthera.2014.06.009_bib13","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1185\/03007990903290886","article-title":"Comparison of pitavastatin with simvastatin in primary hypercholesterolaemia or combined dyslipidaemia [Published correction appears in Curr Med Res Opin. 2010;26:1046. Dosage error in article text]","volume":"25","author":"Ose","year":"2009","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.clinthera.2014.06.009_bib14","doi-asserted-by":"crossref","first-page":"291","DOI":"10.2217\/clp.09.20","article-title":"Pitavastatin compared with atorvastatin in primary hypercholesterolemia or combined dyslipidemia","volume":"4","author":"Budinski","year":"2009","journal-title":"Clin Lipidol"},{"key":"10.1016\/j.clinthera.2014.06.009_bib15","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1111\/j.1463-1326.2011.01477.x","article-title":"Comparative long-term efficacy and tolerability of pitavastatin 4 mg and atorvastatin 20-40 mg in patients with type 2 diabetes mellitus and combined (mixed) dyslipidaemia","volume":"13","author":"Gumprecht","year":"2011","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.clinthera.2014.06.009_bib16","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1253\/circj.CJ-10-1281","article-title":"for the PATROL Trial Investigators. Randomized head-to-head comparison of pitavastatin, atorvastatin, and rosuvastatin for safety and efficacy (quantity and quality of LDL): the PATROL trial","volume":"75","author":"Saku","year":"2011","journal-title":"Circ J"},{"key":"10.1016\/j.clinthera.2014.06.009_bib17","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/2047487312451251","article-title":"Pitavastatin shows greater lipid-lowering efficacy over 12 weeks than pravastatin in elderly patients with primary hypercholesterolaemia or combined (mixed) dyslipidaemia","volume":"20","author":"Stender","year":"2013","journal-title":"Eur J Prev Cardiol"},{"issue":"Suppl 13","key":"10.1016\/j.clinthera.2014.06.009_bib18","doi-asserted-by":"crossref","first-page":"E1692","DOI":"10.1016\/S0735-1097(12)61693-3","volume":"59","author":"Kryzhanovski","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"4 Suppl 1","key":"10.1016\/j.clinthera.2014.06.009_bib19","first-page":"89","article-title":"Neutral effects of pitavastatin and pravastatin on fasting plasma glucose over 12 weeks in elderly patients with primary hyperlipidemia or mixed dyslipidemia","volume":"37","author":"Sponseller","year":"2012","journal-title":"Minerva Endocrinol"},{"key":"10.1016\/j.clinthera.2014.06.009_bib20","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0021-9150(90)90185-L","article-title":"Efficacy and safety of pravastatin in patients with primary hypercholesterolemia. I. A dose-response study","volume":"85","author":"Hunninghake","year":"1990","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clinthera.2014.06.009_bib21","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0002-9149(03)00530-7","article-title":"Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR Trial)","volume":"92","author":"Jones","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.clinthera.2014.06.009_bib22","series-title":"Pravachol [prescribing information]","year":"2012"},{"key":"10.1016\/j.clinthera.2014.06.009_bib23","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1177\/2047487313480435","article-title":"Comparative benefits of statins in the primary and secondary prevention of major coronary events and all-cause mortality: a network meta-analysis of placebo-controlled and active-comparator trials","volume":"20","author":"Naci","year":"2013","journal-title":"Eur J Prev Cardiol"}],"container-title":["Clinical Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149291814003725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149291814003725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T06:35:50Z","timestamp":1565591750000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149291814003725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0149291814003725"],"URL":"https:\/\/doi.org\/10.1016\/j.clinthera.2014.06.009","relation":{},"ISSN":["0149-2918"],"issn-type":[{"value":"0149-2918","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}