{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:42:35Z","timestamp":1788864155980,"version":"build-2803163510"},"reference-count":148,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics in Laboratory Medicine"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.cll.2009.07.011","type":"journal-article","created":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T09:13:41Z","timestamp":1257326021000},"page":"741-755","source":"Crossref","is-referenced-by-count":22,"title":["Respiratory Viruses in Bronchiolitis and Their Link to Recurrent Wheezing and Asthma"],"prefix":"10.1016","volume":"29","author":[{"given":"Jonathan M.","family":"Mansbach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Carlos A.","family":"Camargo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0022-3476(71)80218-4","article-title":"Epidemiologic patterns of acute lower respiratory disease of children in a pediatric group practice","volume":"78","author":"Glezen","year":"1971","journal-title":"J Pediatr"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1542\/peds.2007-2087","article-title":"Increasing burden and risk factors for bronchiolitis-related medical visits in infants enrolled in a state health care insurance plan","volume":"122","author":"Carroll","year":"2008","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib3","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1164\/rccm.200603-435PP","article-title":"Bronchiolitis to asthma: a review and call for studies of gene-virus interactions in asthma causation","volume":"175","author":"Singh","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib4","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1183\/09031936.00002108","article-title":"Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach","volume":"32","author":"Brand","year":"2008","journal-title":"Eur Respir J"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib5","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1164\/ajrccm.161.5.9906076","article-title":"Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7","volume":"161","author":"Sigurs","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib6","doi-asserted-by":"crossref","first-page":"218","DOI":"10.5694\/j.1326-5377.1997.tb138856.x","article-title":"Asthma in children","volume":"167","author":"Wainwright","year":"1997","journal-title":"Med J Aust"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib7","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1164\/ajrccm\/146.4.888","article-title":"A community-based study of the epidemiology of asthma. Incidence rates, 1964\u20131983","volume":"146","author":"Yunginger","year":"1992","journal-title":"Am Rev Respir Dis"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1513\/pats.200607-144JG","article-title":"Gene-environment interactions in asthma: with apologies to William of Ockham","volume":"4","author":"Martinez","year":"2007","journal-title":"Proc Am Thorac Soc"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib9","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1542\/peds.2007-1392","article-title":"Infectious disease hospitalizations among infants in the United States","volume":"121","author":"Yorita","year":"2008","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib10","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1542\/peds.2006-2223","article-title":"Diagnosis and management of bronchiolitis","volume":"118","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.cll.2009.07.011_bib11","series-title":"Oski's pediatrics principles and practice","first-page":"1214","article-title":"Bronchiolitis","author":"Hanson","year":"1999"},{"key":"10.1016\/j.cll.2009.07.011_bib12","series-title":"Textbook of pediatric emergency medicine","first-page":"754","article-title":"Infectious disease emergencies","author":"Fleisher","year":"2000"},{"key":"10.1016\/j.cll.2009.07.011_bib13","series-title":"Textbook of pediatric infectious diseases","first-page":"273","article-title":"Bronchiolitis and infectious asthma","author":"Welliver","year":"2004"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib14","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jpeds.2007.05.041","article-title":"Acute viral bronchiolitis: to treat or not to treat-that is the question","volume":"151","author":"Calogero","year":"2007","journal-title":"J Pediatr"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib15","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1542\/peds.109.1.68","article-title":"Heliox therapy in infants with acute bronchiolitis","volume":"109","author":"Martinon-Torres","year":"2002","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib16","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jpeds.2007.04.010","article-title":"Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants","volume":"151","author":"Kuzik","year":"2007","journal-title":"J Pediatr"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib17","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1056\/NEJMoa071255","article-title":"A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis","volume":"357","author":"Corneli","year":"2007","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib18","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/INF.0b013e31818ee0c1","article-title":"Bronchiolitis: age and previous wheezing episodes are linked to viral etiology and atopic characteristics","volume":"28","author":"Jartti","year":"2009","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.cll.2009.07.011_bib19","doi-asserted-by":"crossref","first-page":"e573","DOI":"10.1542\/peds.2008-1675","article-title":"Variability in the diagnostic labeling of nonbacterial lower respiratory tract infections: a multicenter study of children who presented to the Emergency Department","volume":"123","author":"Mansbach","year":"2009","journal-title":"Pediatrics"},{"issue":"15","key":"10.1016\/j.cll.2009.07.011_bib20","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1001\/jama.282.15.1440","article-title":"Bronchiolitis-associated hospitalizations among US children, 1980\u20131996","volume":"282","author":"Shay","year":"1999","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.cll.2009.07.011_bib21","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/00006454-200207000-00005","article-title":"Respiratory syncytial virus-coded pediatric hospitalizations, 1997 to 1999","volume":"21","author":"Leader","year":"2002","journal-title":"Pediatr Infect Dis J"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib22","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1542\/peds.2006-1193","article-title":"Direct medical costs of bronchiolitis hospitalizations in the United States","volume":"118","author":"Pelletier","year":"2006","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib23","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1093\/infdis\/162.6.1283","article-title":"Occurrence of groups A and B of respiratory syncytial virus over 15 years: associated epidemiologic and clinical characteristics in hospitalized and ambulatory children","volume":"162","author":"Hall","year":"1990","journal-title":"J Infect Dis"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib24","first-page":"543","article-title":"Risk of primary infection and reinfection with respiratory syncytial virus","volume":"140","author":"Glezen","year":"1986","journal-title":"Am J Dis Child"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib25","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/jmv.1890130204","article-title":"Age-specific prevalence of complement-fixing antibodies to sixteen viral antigens: a computer analysis of 58,500 patients covering a period of eight years","volume":"13","author":"Ukkonen","year":"1984","journal-title":"J Med Virol"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib26","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1542\/peds.113.6.1728","article-title":"Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections","volume":"113","author":"Levine","year":"2004","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib27","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1067\/mpd.2000.110531","article-title":"Rates of hospitalization for respiratory syncytial virus infection among children in medicaid","volume":"137","author":"Boyce","year":"2000","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib28","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0022-3476(95)70547-3","article-title":"Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection","volume":"126","author":"Wang","year":"1995","journal-title":"J Pediatr"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib29","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1542\/peds.108.4.851","article-title":"Effect of practice variation on resource utilization in infants hospitalized for viral lower respiratory illness","volume":"108","author":"Willson","year":"2001","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib30","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/01.inf.0000069765.43405.3b","article-title":"Risk factors for bronchiolitis-associated deaths among infants in the United States","volume":"22","author":"Holman","year":"2003","journal-title":"Pediatr Infect Dis J"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib31","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1086\/317655","article-title":"Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979\u20131997","volume":"183","author":"Shay","year":"2001","journal-title":"J Infect Dis"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib32","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1086\/315513","article-title":"Rhinoviruses infect the lower airways","volume":"181","author":"Papadopoulos","year":"2000","journal-title":"J Infect Dis"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib33","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1097\/01.inf.0000143642.72480.53","article-title":"Rhinovirus-associated wheezing in infancy: comparison with respiratory syncytial virus bronchiolitis","volume":"23","author":"Korppi","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib34","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/89098","article-title":"A newly discovered human pneumovirus isolated from young children with respiratory tract disease","volume":"7","author":"van den Hoogen","year":"2001","journal-title":"Nat Med"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib35","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1001\/jama.292.11.1333","article-title":"Influenza-associated hospitalizations in the United States","volume":"292","author":"Thompson","year":"2004","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib36","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJM200001273420401","article-title":"The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children","volume":"342","author":"Neuzil","year":"2000","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib37","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1542\/peds.113.6.1758","article-title":"Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children","volume":"113","author":"Iwane","year":"2004","journal-title":"Pediatrics"},{"issue":"1 Pt 1","key":"10.1016\/j.cll.2009.07.011_bib38","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1542\/peds.113.1.e51","article-title":"Adenoviral infections in children: the impact of rapid diagnosis","volume":"113","author":"Rocholl","year":"2004","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib39","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1542\/peds.76.3.420","article-title":"Adenovirus infections in young children","volume":"76","author":"Edwards","year":"1985","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib40","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/oxfordjournals.aje.a121171","article-title":"Seroepidemiologic studies of coronavirus infection in adults and children","volume":"91","author":"McIntosh","year":"1970","journal-title":"Am J Epidemiol"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib41","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nm1024","article-title":"Identification of a new human coronavirus","volume":"10","author":"van der Hoek","year":"2004","journal-title":"Nat Med"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib42","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1086\/428138","article-title":"Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children","volume":"191","author":"Esper","year":"2005","journal-title":"J Infect Dis"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib43","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1128\/JVI.79.2.884-895.2005","article-title":"Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia","volume":"79","author":"Woo","year":"2005","journal-title":"J Virol"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib44","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/JCM.02614-05","article-title":"Coronavirus HKU1 and other coronavirus infections in Hong Kong","volume":"44","author":"Lau","year":"2006","journal-title":"J Clin Microbiol"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib45","doi-asserted-by":"crossref","first-page":"775","DOI":"10.3201\/eid1205.051316","article-title":"Coronavirus HKU1 infection in the United States","volume":"12","author":"Esper","year":"2006","journal-title":"Emerg Infect Dis"},{"issue":"36","key":"10.1016\/j.cll.2009.07.011_bib46","doi-asserted-by":"crossref","first-page":"12891","DOI":"10.1073\/pnas.0504666102","article-title":"Cloning of a human parvovirus by molecular screening of respiratory tract samples","volume":"102","author":"Allander","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib47","doi-asserted-by":"crossref","first-page":"862","DOI":"10.3201\/eid1205.051523","article-title":"Human bocavirus in children","volume":"12","author":"Foulongne","year":"2006","journal-title":"Emerg Infect Dis"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib48","doi-asserted-by":"crossref","first-page":"848","DOI":"10.3201\/eid1205.051424","article-title":"Human bocavirus infection, Canada","volume":"12","author":"Bastien","year":"2006","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib49","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1128\/JCM.44.3.1132-1134.2006","article-title":"Detection of human bocavirus in Japanese children with lower respiratory tract infections","volume":"44","author":"Ma","year":"2006","journal-title":"J Clin Microbiol"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib50","doi-asserted-by":"crossref","first-page":"e64","DOI":"10.1371\/journal.ppat.0030064","article-title":"Identification of a novel polyomavirus from patients with acute respiratory tract infections","volume":"3","author":"Gaynor","year":"2007","journal-title":"PLoS Pathog"},{"issue":"8","key":"10.1016\/j.cll.2009.07.011_bib51","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1128\/JVI.00028-07","article-title":"Identification of a third human polyomavirus","volume":"81","author":"Allander","year":"2007","journal-title":"J Virol"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib52","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.3201\/eid1411.080394","article-title":"Role of human polyomaviruses in respiratory tract disease in young children","volume":"14","author":"Wattier","year":"2008","journal-title":"Emerg Infect Dis"},{"issue":"12","key":"10.1016\/j.cll.2009.07.011_bib53","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1136\/adc.2004.049551","article-title":"Pulmonary and systemic bacterial co-infections in severe RSV bronchiolitis","volume":"89","author":"Duttweiler","year":"2004","journal-title":"Arch Dis Child"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib54","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0022-3476(88)80263-4","article-title":"Risk of secondary bacterial infection in infants hospitalized with respiratory syncytial viral infection","volume":"113","author":"Hall","year":"1988","journal-title":"J Pediatr"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib55","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1097\/01.inf.0000143647.88873.66","article-title":"Risk of bacterial infection in previously healthy respiratory syncytial virus-infected young children admitted to the intensive care unit","volume":"23","author":"Randolph","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"7","key":"10.1016\/j.cll.2009.07.011_bib56","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1136\/thx.2005.048397","article-title":"High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis","volume":"61","author":"Thorburn","year":"2006","journal-title":"Thorax"},{"issue":"1 Suppl","key":"10.1016\/j.cll.2009.07.011_bib57","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1097\/01.inf.0000108188.37237.48","article-title":"National disease burden of respiratory viruses detected in children by polymerase chain reaction","volume":"23","author":"Henrickson","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib58","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jaci.2004.04.006","article-title":"Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing","volume":"114","author":"Heymann","year":"2004","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib59","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1097\/01.inf.0000143648.04673.6c","article-title":"Viral etiology of acute respiratory tract infections in children presenting to hospital: role of polymerase chain reaction and demonstration of multiple infections","volume":"23","author":"Jennings","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib60","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/jmv.21108","article-title":"Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease","volume":"80","author":"Canducci","year":"2008","journal-title":"J Med Virol"},{"issue":"7","key":"10.1016\/j.cll.2009.07.011_bib61","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/01.inf.0000168741.59747.2d","article-title":"Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response","volume":"24","author":"Aberle","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib62","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1056\/NEJMoa025472","article-title":"Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children","volume":"350","author":"Williams","year":"2004","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib63","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.jaci.2005.06.024","article-title":"Rhinovirus illnesses during infancy predict subsequent childhood wheezing","volume":"116","author":"Lemanske","year":"2005","journal-title":"J Allergy Clin Immunol"},{"issue":"7","key":"10.1016\/j.cll.2009.07.011_bib64","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/01.inf.0000168747.94999.aa","article-title":"Frequency of detection of picornaviruses and seven other respiratory pathogens in infants","volume":"24","author":"Legg","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib65","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/INF.0b013e31815922c8","article-title":"Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study","volume":"27","author":"Regamey","year":"2008","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib66","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/01.inf.0000207395.80657.cf","article-title":"Comparison of human metapneumovirus, respiratory syncytial virus and influenza A virus lower respiratory tract infections in hospitalized young children","volume":"25","author":"Wolf","year":"2006","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib67","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1553-2712.2007.00034.x","article-title":"Prospective multicenter study of the viral etiology of bronchiolitis in the emergency department","volume":"15","author":"Mansbach","year":"2008","journal-title":"Acad Emerg Med"},{"issue":"8","key":"10.1016\/j.cll.2009.07.011_bib68","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1097\/01.inf.0000226912.88900.a3","article-title":"Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study","volume":"25","author":"Kusel","year":"2006","journal-title":"Pediatr Infect Dis J"},{"issue":"7705","key":"10.1016\/j.cll.2009.07.011_bib69","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0140-6736(71)92440-8","article-title":"Respiratory syncytial and other viruses associated with respiratory disease in infants","volume":"1","author":"Jacobs","year":"1971","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib70","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/S0022-3476(84)80943-9","article-title":"A simultaneous outbreak of respiratory syncytial virus and parainfluenza virus type 3 in a newborn nursery","volume":"104","author":"Meissner","year":"1984","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib71","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/oxfordjournals.aje.a121128","article-title":"Viruses, Mycoplasma pneumoniae and bacteria associated with lower respiratory tract disease among infants","volume":"91","author":"Mufson","year":"1970","journal-title":"Am J Epidemiol"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib72","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00006454-199301000-00005","article-title":"Respiratory syncytial virus-associated lower respiratory illnesses: possible influence of other agents. The Group Health Medical Associates","volume":"12","author":"Ray","year":"1993","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib73","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0022-3476(86)80993-3","article-title":"Isolation of viruses from specimens submitted for direct immunofluorescence test for respiratory syncytial virus","volume":"108","author":"Waner","year":"1986","journal-title":"J\u00a0Pediatr"},{"issue":"5952","key":"10.1016\/j.cll.2009.07.011_bib74","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1136\/bmj.1.5952.235","article-title":"Role of respiratory viruses in childhood mortality","volume":"1","author":"Downham","year":"1975","journal-title":"Br Med J"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib75","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1093\/oxfordjournals.aje.a120548","article-title":"Multiple respiratory virus infections in hospitalized children","volume":"82","author":"Portnoy","year":"1965","journal-title":"Am J Epidemiol"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib76","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0732-8893(89)90098-9","article-title":"Detection of multiple viral agents in nasopharyngeal specimens yielding respiratory syncytial virus (RSV). An assessment of diagnostic strategy and clinical significance","volume":"12","author":"Subbarao","year":"1989","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib77","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1086\/516137","article-title":"Dual respiratory virus infections","volume":"25","author":"Drews","year":"1997","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib78","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/01.inf.0000207480.55201.f6","article-title":"Human metapneumovirus infection in young children hospitalized with respiratory tract disease","volume":"25","author":"Foulongne","year":"2006","journal-title":"Pediatr Infect Dis J"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib79","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3201\/eid0903.020289","article-title":"Human metapneumovirus in severe respiratory syncytial virus bronchiolitis","volume":"9","author":"Greensill","year":"2003","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib80","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1086\/426457","article-title":"Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis","volume":"191","author":"Semple","year":"2005","journal-title":"J Infect Dis"},{"issue":"20","key":"10.1016\/j.cll.2009.07.011_bib81","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1056\/NEJMoa030634","article-title":"Identification of severe acute respiratory syndrome in Canada","volume":"348","author":"Poutanen","year":"2003","journal-title":"N Engl J Med"},{"issue":"23","key":"10.1016\/j.cll.2009.07.011_bib82","doi-asserted-by":"crossref","first-page":"14992","DOI":"10.1128\/JVI.79.23.14992-14997.2005","article-title":"Human metapneumovirus induces a profile of lung cytokines distinct from that of respiratory syncytial virus","volume":"79","author":"Guerrero-Plata","year":"2005","journal-title":"J Virol"},{"issue":"10","key":"10.1016\/j.cll.2009.07.011_bib83","doi-asserted-by":"crossref","first-page":"5971","DOI":"10.1128\/JVI.79.10.5971-5978.2005","article-title":"The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB\/c mice","volume":"79","author":"Alvarez","year":"2005","journal-title":"J\u00a0Virol"},{"issue":"10","key":"10.1016\/j.cll.2009.07.011_bib84","doi-asserted-by":"crossref","first-page":"5848","DOI":"10.4049\/jimmunol.176.10.5848","article-title":"Human metapneumovirus elicits weak IFN-\u03b3 memory Responses compared with respiratory syncytial virus","volume":"176","author":"Douville","year":"2006","journal-title":"J Immunol"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib85","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.micinf.2005.07.001","article-title":"Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?","volume":"8","author":"Mahalingam","year":"2006","journal-title":"Microbes Infect"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib86","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1165\/rcmb.2005-0287OC","article-title":"Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus","volume":"34","author":"Guerrero-Plata","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib87","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1086\/383350","article-title":"Differential production of inflammatory cytokines in primary infection with human metapneumovirus and with other common respiratory viruses of infancy","volume":"189","author":"Laham","year":"2004","journal-title":"J Infect Dis"},{"key":"10.1016\/j.cll.2009.07.011_bib88","series-title":"Prospective multicenter study of the etiology of bronchiolitis admissions 2007\u20132008","author":"Piedra","year":"2009"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib89","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0021-8707(59)90054-1","article-title":"The relationship between bronchiolitis and childhood asthma; a follow-up study of 100 cases of bronchiolitis","volume":"30","author":"Wittig","year":"1959","journal-title":"J Allergy"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib90","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/ppul.1950030308","article-title":"Acute bronchiolitis: predisposing factors and characterization of infants at risk","volume":"3","author":"Carlsen","year":"1987","journal-title":"Pediatr Pulmonol"},{"issue":"12","key":"10.1016\/j.cll.2009.07.011_bib91","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/BF01957225","article-title":"Recurrent wheezing in children with respiratory syncytial virus (RSV) bronchiolitis in Qatar","volume":"152","author":"Osundwa","year":"1993","journal-title":"Eur J Pediatr"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib92","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1542\/peds.95.4.500","article-title":"Asthma and immunoglobulin E\u00a0antibodies after respiratory syncytial virus bronchiolitis: a prospective cohort study with matched controls","volume":"95","author":"Sigurs","year":"1995","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib93","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1183\/09031936.00062907","article-title":"Do childhood respiratory infections continue to influence adult respiratory morbidity?","volume":"33","author":"Dharmage","year":"2009","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib94","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1164\/rccm.200406-730OC","article-title":"Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13","volume":"171","author":"Sigurs","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"9178","key":"10.1016\/j.cll.2009.07.011_bib95","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0140-6736(98)10321-5","article-title":"Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years","volume":"354","author":"Stein","year":"1999","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib96","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.jaci.2009.02.021","article-title":"The severity-dependent relationship of infant bronchiolitis on the risk and morbidity of early childhood asthma","volume":"123","author":"Carroll","year":"2009","journal-title":"J Allergy Clin Immunol"},{"issue":"20","key":"10.1016\/j.cll.2009.07.011_bib97","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1056\/NEJMe0902242","article-title":"The challenge of managing wheezing in infants","volume":"360","author":"Frey","year":"2009","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib98","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1081-1206(10)60826-5","article-title":"Asthma: a syndrome composed of heterogeneous diseases","volume":"101","author":"Borish","year":"2008","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib99","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jaci.2006.06.020","article-title":"The natural history of asthma","volume":"118","author":"Reed","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.cll.2009.07.011_bib100","doi-asserted-by":"crossref","DOI":"10.1111\/j.1398-9995.2009.02022.x","article-title":"Recurrent wheezing after respiratory syncytial virus or non-respiratory syncytial virus bronchiolitis in infancy: a 3-year follow-up","author":"Valkonen","year":"2009","journal-title":"Allergy"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib101","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/(SICI)1099-0496(199808)26:2<113::AID-PPUL7>3.0.CO;2-N","article-title":"One-year follow-up of young children hospitalized for wheezing: the influence of early anti-inflammatory therapy and risk factors for\u00a0subsequent wheezing and asthma","volume":"26","author":"Reijonen","year":"1998","journal-title":"Pediatr Pulmonol"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib102","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1542\/peds.106.6.1406","article-title":"Predictors of asthma three years after hospital admission for wheezing in infancy","volume":"106","author":"Reijonen","year":"2000","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib103","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/ppul.20578","article-title":"Relationship of early childhood viral exposures to respiratory symptoms, onset of possible asthma and atopy in high risk children: the Canadian asthma primary prevention study","volume":"42","author":"Lee","year":"2007","journal-title":"Pediatr Pulmonol"},{"issue":"8","key":"10.1016\/j.cll.2009.07.011_bib104","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1086\/368411","article-title":"Asthma exacerbations in children associated with rhinovirus but not human metapneumovirus infection","volume":"187","author":"Rawlinson","year":"2003","journal-title":"J\u00a0Infect Dis"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib105","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1086\/503809","article-title":"The relationship of rhinovirus-associated asthma hospitalizations with inhaled corticosteroids and smoking","volume":"193","author":"Venarske","year":"2006","journal-title":"J Infect Dis"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib106","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1164\/ajrccm.159.3.9801052","article-title":"Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses","volume":"159","author":"Rakes","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib107","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.jaci.2006.04.032","article-title":"Human rhinovirus in bronchial epithelium of infants with recurrent respiratory symptoms","volume":"118","author":"Malmstrom","year":"2006","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib108","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jaci.2006.11.555","article-title":"Wheezing severe rhinovirus illnesses during infancy predict childhood asthma at age 6 years","volume":"119","author":"Roberg","year":"2007","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib109","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1067\/mai.2003.33","article-title":"Rhinovirus-induced wheezing in infancy\u2014the first sign of childhood asthma?","volume":"111","author":"Kotaniemi-Syrjanen","year":"2003","journal-title":"J Allergy Clin Immunol"},{"issue":"7","key":"10.1016\/j.cll.2009.07.011_bib110","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1164\/rccm.200802-309OC","article-title":"Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children","volume":"178","author":"Jackson","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib111","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.jaci.2008.12.011","article-title":"Season of infant bronchiolitis and estimates of subsequent risk and burden of early childhood asthma","volume":"123","author":"Carroll","year":"2009","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib112","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/01.inf.0000215226.69696.0c","article-title":"Evaluation of the efficacy of prednisolone in early wheezing induced by rhinovirus or respiratory syncytial virus","volume":"25","author":"Jartti","year":"2006","journal-title":"Pediatr Infect Dis J"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib113","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.jaci.2006.11.003","article-title":"Prednisolone reduces recurrent wheezing after a first wheezing episode associated with rhinovirus infection or eczema","volume":"119","author":"Lehtinen","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"15","key":"10.1016\/j.cll.2009.07.011_bib114","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1056\/NEJMoa052632","article-title":"Childhood asthma after bacterial colonization of the airway in neonates","volume":"357","author":"Bisgaard","year":"2007","journal-title":"N Engl J Med"},{"issue":"5 Suppl","key":"10.1016\/j.cll.2009.07.011_bib115","doi-asserted-by":"crossref","first-page":"S118","DOI":"10.1067\/S0022-3476(03)00511-0","article-title":"Environmental and demographic risk factors for respiratory syncytial virus lower respiratory tract disease","volume":"143","author":"Simoes","year":"2003","journal-title":"J Pediatr."},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib116","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1056\/NEJM199501193320301","article-title":"Asthma and wheezing in the first six years of life. The Group Health Medical Associates","volume":"332","author":"Martinez","year":"1995","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib117","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.jaci.2004.09.020","article-title":"Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma","volume":"114","author":"Guilbert","year":"2004","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib118","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1164\/rccm.200804-579OC","article-title":"Evidence of a causal role of winter virus infection during infancy in early childhood asthma","volume":"178","author":"Wu","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib119","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1183\/09031936.00066307","article-title":"Wheezing in childhood: incidence, longitudinal patterns and factors predicting persistence","volume":"32","author":"Matricardi","year":"2008","journal-title":"Eur Respir J"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib120","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1542\/peds.2007-3323","article-title":"Bronchiolitis: lingering questions about its definition and the potential role of vitamin D","volume":"122","author":"Mansbach","year":"2008","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib121","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1210\/jcem-67-2-373","article-title":"Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin","volume":"67","author":"Webb","year":"1988","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib122","doi-asserted-by":"crossref","first-page":"62","DOI":"10.5694\/j.1326-5377.1990.tb124456.x","article-title":"The role of childhood exposure to sunlight in the development of solar keratoses and non-melanocytic skin cancer","volume":"152","author":"Marks","year":"1990","journal-title":"Med J Aust"},{"issue":"4","key":"10.1016\/j.cll.2009.07.011_bib123","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1002\/(SICI)1097-0215(19980812)77:4<533::AID-IJC10>3.0.CO;2-7","article-title":"Influence of sun exposures during childhood and during adulthood on melanoma risk. EPIMEL and EORTC Melanoma Cooperative Group. European Organisation for Research and Treatment of Cancer","volume":"77","author":"Autier","year":"1998","journal-title":"Int J Cancer"},{"issue":"17","key":"10.1016\/j.cll.2009.07.011_bib124","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJM199904293401707","article-title":"The pathogenesis of melanoma induced by ultraviolet radiation","volume":"340","author":"Gilchrest","year":"1999","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib125","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/00007611-200101000-00011","article-title":"Balancing cutaneous and systemic considerations","volume":"94","author":"Fuller","year":"2001","journal-title":"South Med J"},{"issue":"1","key":"10.1016\/j.cll.2009.07.011_bib126","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/0009922806289311","article-title":"Vitamin D deficiency in a healthy group of mothers and newborn infants","volume":"46","author":"Lee","year":"2007","journal-title":"Clin Pediatr (Phila)"},{"issue":"2","key":"10.1016\/j.cll.2009.07.011_bib127","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1542\/peds.2006-0108","article-title":"Vitamin D deficiency in breastfed infants in Iowa","volume":"118","author":"Ziegler","year":"2006","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.cll.2009.07.011_bib128","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1164\/rccm.200403-412OC","article-title":"Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy","volume":"170","author":"Poon","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"10.1016\/j.cll.2009.07.011_bib129","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1164\/rccm.200404-447OC","article-title":"Association of vitamin D receptor gene polymorphisms with childhood and adult asthma","volume":"170","author":"Raby","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.cll.2009.07.011_bib130","first-page":"526","article-title":"Low levels of dietary vitamin D intake and pulmonary function in adolescents","volume":"3","author":"Burns","year":"2006","journal-title":"Proc Am Thorac Soc"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib131","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1378\/chest.128.6.3792","article-title":"Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination survey","volume":"128","author":"Black","year":"2005","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib132","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1093\/ajcn\/85.3.788","article-title":"Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age","volume":"85","author":"Camargo","year":"2007","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib133","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/ajcn\/85.3.853","article-title":"Maternal vitamin D intake during pregnancy and early childhood wheezing","volume":"85","author":"Devereux","year":"2007","journal-title":"Am J Clin Nutr"},{"issue":"Suppl","key":"10.1016\/j.cll.2009.07.011_bib134","first-page":"A993","article-title":"Cord blood 25-hydroxyvitamin D levels and risk of childhood wheeze in New Zealand","volume":"177","author":"Camargo","year":"2008","journal-title":"Am J Respir Crit Care Med."},{"issue":"suppl","key":"10.1016\/j.cll.2009.07.011_bib135","first-page":"A993","article-title":"Low serum vitamin D levels are associated with greater risks for severe exacerbations in childhood asthmatics","volume":"177","author":"Litonjua","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"issue":"15","key":"10.1016\/j.cll.2009.07.011_bib136","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1056\/NEJM200010123431501","article-title":"Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group","volume":"343","year":"2000","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.cll.2009.07.011_bib137","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1164\/rccm.200808-1361OC","article-title":"Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica","volume":"179","author":"Brehm","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.cll.2009.07.011_bib138","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.4049\/jimmunol.173.5.2909","article-title":"Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression","volume":"173","author":"Wang","year":"2004","journal-title":"J Immunol"},{"issue":"3","key":"10.1016\/j.cll.2009.07.011_bib139","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1172\/JCI30142","article-title":"Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism","volume":"117","author":"Schauber","year":"2007","journal-title":"J\u00a0Clin Invest"},{"issue":"11","key":"10.1016\/j.cll.2009.07.011_bib140","doi-asserted-by":"crossref","first-page":"7190","DOI":"10.4049\/jimmunol.178.11.7190","article-title":"IFN-\u03b3- and TNF-independent vitamin D-inducible human suppression of Mycobacteria: the role of cathelicidin LL-37","volume":"178","author":"Martineau","year":"2007","journal-title":"J Immunol"},{"issue":"9","key":"10.1016\/j.cll.2009.07.011_bib141","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/nri1180","article-title":"Defensins: antimicrobial peptides of innate immunity","volume":"3","author":"Ganz","year":"2003","journal-title":"Nat Rev Immunol"},{"issue":"6862","key":"10.1016\/j.cll.2009.07.011_bib142","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/35106587","article-title":"Innate antimicrobial peptide protects the skin from invasive bacterial infection","volume":"414","author":"Nizet","year":"2001","journal-title":"Nature"},{"issue":"5595","key":"10.1016\/j.cll.2009.07.011_bib143","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1126\/science.1076185","article-title":"Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor","volume":"298","author":"Zhang","year":"2002","journal-title":"Science"},{"issue":"10","key":"10.1016\/j.cll.2009.07.011_bib144","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/ni1248","article-title":"Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins","volume":"6","author":"Leikina","year":"2005","journal-title":"Nat Immunol"},{"issue":"1\u20133","key":"10.1016\/j.cll.2009.07.011_bib145","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0167-0115(01)00282-8","article-title":"Human alpha-defensin 1 (HNP-1) inhibits adenoviral infection in vitro","volume":"101","author":"Bastian","year":"2001","journal-title":"Regul Pept"},{"issue":"5768","key":"10.1016\/j.cll.2009.07.011_bib146","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1126\/science.1123933","article-title":"Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response","volume":"311","author":"Liu","year":"2006","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.cll.2009.07.011_bib147","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1086\/520886","article-title":"Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes","volume":"196","author":"Janssen","year":"2007","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.cll.2009.07.011_bib148","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1086\/527488","article-title":"Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood","volume":"197","author":"Roth","year":"2008","journal-title":"J Infect Dis"}],"container-title":["Clinics in Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272271209000663?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272271209000663?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T11:36:54Z","timestamp":1685187414000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272271209000663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":148,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0272271209000663"],"URL":"https:\/\/doi.org\/10.1016\/j.cll.2009.07.011","relation":{},"ISSN":["0272-2712"],"issn-type":[{"value":"0272-2712","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}