{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:46:25Z","timestamp":1789757185792,"version":"4.0.1"},"reference-count":66,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","labmed.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Laboratory Medicine"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.cll.2015.07.005","type":"journal-article","created":{"date-parts":[[2015,8,31]],"date-time":"2015-08-31T21:04:18Z","timestamp":1441055058000},"page":"815-825","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Alternatives to Serologic Testing for Diagnosis of Lyme Disease"],"prefix":"10.1016","volume":"35","author":[{"given":"Kevin","family":"Alby","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald A.","family":"Capraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.cll.2015.07.005_bib1","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1172\/JCI21681","article-title":"The emergence of Lyme disease","volume":"113","author":"Steere","year":"2004","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.cll.2015.07.005_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.cll.2015.08.001","article-title":"Lyme disease diagnosis: serology","author":"Schriefer","year":"2015","journal-title":"Clin Lab Med"},{"issue":"13","key":"10.1016\/j.cll.2015.07.005_bib3","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1056\/NEJM198303313081302","article-title":"Spirochetes isolated from the blood of two patients with Lyme disease","volume":"308","author":"Benach","year":"1983","journal-title":"N\u00a0Engl J Med"},{"issue":"3995","key":"10.1016\/j.cll.2015.07.005_bib4","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1126\/science.173.3995.443","article-title":"Cultivation of Borrelia hermsi","volume":"173","author":"Kelly","year":"1971","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib5","first-page":"521","article-title":"Isolation and cultivation of Lyme disease spirochetes","volume":"57","author":"Barbour","year":"1984","journal-title":"Yale J Biol Med"},{"issue":"5","key":"10.1016\/j.cll.2015.07.005_bib6","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1128\/JCM.31.5.1251-1255.1993","article-title":"Standardization of medium for culturing Lyme disease spirochetes","volume":"31","author":"Pollack","year":"1993","journal-title":"J\u00a0Clin Microbiol"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1128\/JCM.28.2.363-365.1990","article-title":"Effects of bovine serum albumin on the ability of Barbour-Stoenner-Kelly medium to detect Borrelia burgdorferi","volume":"28","author":"Callister","year":"1990","journal-title":"J\u00a0Clin Microbiol"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib8","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.diagmicrobio.2012.03.026","article-title":"Comparison of five diagnostic modalities for direct detection of Borrelia burgdorferi in patients with early Lyme disease","volume":"73","author":"Liveris","year":"2012","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"12","key":"10.1016\/j.cll.2015.07.005_bib9","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1086\/324490","article-title":"Laboratory diagnostic techniques for patients with early Lyme disease associated with erythema migrans: a comparison of different techniques","volume":"33","author":"Nowakowski","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib10","doi-asserted-by":"crossref","first-page":"362","DOI":"10.7150\/ijms.5698","article-title":"Improved culture conditions for the growth\u00a0and detection of Borrelia from human serum","volume":"10","author":"Sapi","year":"2013","journal-title":"Int J Med Sci"},{"key":"10.1016\/j.cll.2015.07.005_bib11","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1128\/JCM.00252-14","article-title":"Reply to \u201cno evidence for contamination of Borrelia blood cultures: a review of facts\u201d","volume":"52","author":"Johnson","year":"2014","journal-title":"J\u00a0Clin Microbiol"},{"issue":"15","key":"10.1016\/j.cll.2015.07.005_bib12","first-page":"333","article-title":"Concerns regarding a new culture method for Borrelia burgdorferi not approved for the diagnosis of Lyme disease","volume":"63","author":"Nelson","year":"2014","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"6","key":"10.1016\/j.cll.2015.07.005_bib13","doi-asserted-by":"crossref","first-page":"3138","DOI":"10.1128\/IAI.72.6.3138-3146.2004","article-title":"Borrelia burgdorferi binds to, invades, and colonizes native type I collagen lattices","volume":"72","author":"Zambrano","year":"2004","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib14","doi-asserted-by":"crossref","first-page":"00037","DOI":"10.15406\/jmen.2015.02.00037","article-title":"Increased DNA yield following enzymatic release of Borrelia from a collagen matrix in culture","volume":"2","author":"Wood","year":"2015","journal-title":"Journal of Microbiology and Experimentation"},{"key":"10.1016\/j.cll.2015.07.005_bib15","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1128\/JCM.29.6.1162-1170.1991","article-title":"Immune capture and detection of Borrelia burgdorferi antigens in urine, blood, or tissues from infected ticks, mice, dogs, and humans","volume":"29","author":"Dorward","year":"1991","journal-title":"J\u00a0Clin Microbiol"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib16","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.biomaterials.2010.10.004","article-title":"The use of hydrogel microparticles to sequester and concentrate bacterial antigens in a urine test for Lyme disease","volume":"32","author":"Douglas","year":"2011","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib17","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10096-014-2217-5","article-title":"Evaluation of two commercially available rapid diagnostic tests for Lyme borreliosis","volume":"34","author":"Smit","year":"2015","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"7","key":"10.1016\/j.cll.2015.07.005_bib18","doi-asserted-by":"crossref","first-page":"533","DOI":"10.7326\/0003-4819-115-7-533","article-title":"The T-cell proliferative assay in the diagnosis of Lyme disease","volume":"115","author":"Dressler","year":"1991","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.cll.2015.07.005_bib19","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1001\/archderm.1995.01690180047008","article-title":"Lymphoproliferative responses to Borrelia burgdorferi in patients with erythema migrans, acrodermatitis chronica atrophicans, lymphadenosis benigna cutis, and morphea","volume":"131","author":"Buechner","year":"1995","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.cll.2015.07.005_bib20","doi-asserted-by":"crossref","first-page":"104","DOI":"10.2174\/1874205X01206010104","article-title":"The lymphocyte transformation test for Borrelia detects active Lyme borreliosis and verifies effective antibiotic treatment","volume":"6","author":"von Baehr","year":"2012","journal-title":"Open Neurol J"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib21","doi-asserted-by":"crossref","first-page":"285","DOI":"10.7326\/0003-4819-114-4-285","article-title":"Lymphoproliferative responses to Borrelia burgdorferi in Lyme disease","volume":"114","author":"Zoschke","year":"1991","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib22","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/eji.1830240207","article-title":"Prominent T lymphocyte response to Borrelia burgdorferi from peripheral blood of unexposed donors","volume":"24","author":"Roessner","year":"1994","journal-title":"Eur J Immunol"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-2478(00)00316-3","article-title":"Decreased CD57 lymphocyte subset in patients with chronic Lyme disease","volume":"76","author":"Stricker","year":"2001","journal-title":"Immunol Lett"},{"issue":"8","key":"10.1016\/j.cll.2015.07.005_bib24","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1128\/CVI.00167-09","article-title":"Natural killer cell counts are not different between patients with post-Lyme disease syndrome and controls","volume":"16","author":"Marques","year":"2009","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.cll.2015.07.005_bib25","series-title":"Manual of clinical microbiology","first-page":"1037","article-title":"Borrelia","author":"Schrieffer","year":"2015"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib26","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1128\/CMR.00011-06","article-title":"Coinfections acquired from ixodes ticks","volume":"19","author":"Swanson","year":"2006","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib27","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s15010-010-0062-8","article-title":"Isolation of Borrelia burgdorferi sensu lato from blood of adult patients with borrelial lymphocytoma, Lyme neuroborreliosis, Lyme arthritis and acrodermatitis chronica atrophicans","volume":"39","author":"Maraspin","year":"2011","journal-title":"Infection"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.diagmicrobio.2006.08.005","article-title":"A\u00a0LightCycler TaqMan assay for detection of Borrelia burgdorferi sensu lato in clinical samples","volume":"57","author":"Ivacic","year":"2007","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib29","first-page":"209","article-title":"Molecular and serological diagnosis of Borrelia burgdorferi infection among patients with diagnosed erythema migrans","volume":"14","author":"Kondrusik","year":"2007","journal-title":"Ann Agric Environ Med"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib30","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1128\/JCM.37.4.987-992.1999","article-title":"Rapid and sensitive quantification of Borrelia burgdorferi-infected mouse tissues by continuous fluorescent monitoring of PCR","volume":"37","author":"Morrison","year":"1999","journal-title":"J\u00a0Clin Microbiol"},{"issue":"6","key":"10.1016\/j.cll.2015.07.005_bib31","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1128\/JCM.37.6.1958-1963.1999","article-title":"Quantitative detection of Borrelia burgdorferi by real-time PCR","volume":"37","author":"Pahl","year":"1999","journal-title":"J\u00a0Clin Microbiol"},{"issue":"7","key":"10.1016\/j.cll.2015.07.005_bib32","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1128\/JCM.38.7.2756-2759.2000","article-title":"Rapid differentiation of Borrelia garinii from Borrelia afzelii and Borrelia burgdorferi sensu stricto by LightCycler fluorescence melting curve analysis of a PCR product of the recA gene","volume":"38","author":"Pietila","year":"2000","journal-title":"J\u00a0Clin Microbiol"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib33","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1128\/JCM.37.3.565-569.1999","article-title":"Genetic diversity of Borrelia burgdorferi in Lyme disease patients as determined by culture versus direct PCR with clinical specimens","volume":"37","author":"Liveris","year":"1999","journal-title":"J\u00a0Clin Microbiol"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib34","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1128\/CMR.12.4.633","article-title":"Molecular typing of Borrelia burgdorferi sensu lato: taxonomic, epidemiological, and clinical implications","volume":"12","author":"Wang","year":"1999","journal-title":"Clin Microbiol Rev"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib35","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1086\/314922","article-title":"Association of specific subtypes of Borrelia burgdorferi with hematogenous dissemination in early Lyme disease","volume":"180","author":"Wormser","year":"1999","journal-title":"J\u00a0Infect Dis"},{"issue":"7","key":"10.1016\/j.cll.2015.07.005_bib36","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1128\/IAI.67.7.3518-3524.1999","article-title":"Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans","volume":"67","author":"Seinost","year":"1999","journal-title":"Infect Immun"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib37","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1128\/IAI.68.3.1714-1718.2000","article-title":"Conservation and heterogeneity of vlsE among human and tick isolates of Borrelia burgdorferi","volume":"68","author":"Iyer","year":"2000","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.cll.2015.07.005_bib38","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1128\/JCM.38.7.2557-2562.2000","article-title":"Differentiation of Borrelia burgdorferi sensu lato on the basis of RNA polymerase gene (rpoB) sequences","volume":"38","author":"Lee","year":"2000","journal-title":"J\u00a0Clin Microbiol"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib39","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1128\/CMR.18.3.484-509.2005","article-title":"Diagnosis of Lyme borreliosis","volume":"18","author":"Aguero-Rosenfeld","year":"2005","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib40","first-page":"1","article-title":"Molecular diagnosis of Lyme disease: review and meta-analysis","volume":"6","author":"Dumler","year":"2001","journal-title":"Mol\u00a0Diagn"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib41","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1128\/CMR.10.1.185","article-title":"PCR in laboratory diagnosis of human Borrelia burgdorferi infections","volume":"10","author":"Schmidt","year":"1997","journal-title":"Clin Microbiol Rev"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib42","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1093\/infdis\/169.3.668","article-title":"Target imbalance: disparity of Borrelia burgdorferi genetic material in synovial fluid from Lyme arthritis patients","volume":"169","author":"Persing","year":"1994","journal-title":"J\u00a0Infect Dis"},{"issue":"13\u201314","key":"10.1016\/j.cll.2015.07.005_bib43","first-page":"606","article-title":"Sensitivity of culture and polymerase chain reaction for the etiologic diagnosis of erythema migrans","volume":"114","author":"Zore","year":"2002","journal-title":"Wien Klin Wochenschr"},{"issue":"12","key":"10.1016\/j.cll.2015.07.005_bib44","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1002\/1529-0131(199912)42:12<2705::AID-ANR29>3.0.CO;2-H","article-title":"Lack of Borrelia burgdorferi DNA in synovial samples from patients with antibiotic treatment-resistant Lyme arthritis","volume":"42","author":"Carlson","year":"1999","journal-title":"Arthritis Rheum"},{"issue":"12","key":"10.1016\/j.cll.2015.07.005_bib45","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1128\/JCM.30.12.3082-3088.1992","article-title":"Diagnosis of early Lyme disease by polymerase chain reaction amplification and culture of skin biopsies from erythema migrans lesions","volume":"30","author":"Schwartz","year":"1992","journal-title":"J\u00a0Clin Microbiol"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib46","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2165\/00066982-200005020-00007","article-title":"Diagnostic value of PCR for detection of Borrelia burgdorferi DNA in clinical specimens from patients with erythema migrans and Lyme neuroborreliosis","volume":"5","author":"Lebech","year":"2000","journal-title":"Mol Diagn"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib47","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3109\/07853899909115982","article-title":"Borrelia burgdorferi detected by culture and PCR in clinical relapse of disseminated Lyme borreliosis","volume":"31","author":"Oksi","year":"1999","journal-title":"Ann Med"},{"issue":"5","key":"10.1016\/j.cll.2015.07.005_bib48","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1128\/JCM.38.5.1895-1900.2000","article-title":"Direct molecular typing of Borrelia burgdorferi sensu lato species in synovial samples from patients with Lyme arthritis","volume":"38","author":"Jaulhac","year":"2000","journal-title":"J\u00a0Clin Microbiol"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib49","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1099\/00222615-35-2-98","article-title":"Detection of Borrelia burgdorferi in cerebrospinal fluid by the polymerase chain reaction","volume":"35","author":"Kruger","year":"1991","journal-title":"J\u00a0Med Microbiol"},{"issue":"7","key":"10.1016\/j.cll.2015.07.005_bib50","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1128\/JCM.30.7.1646-1653.1992","article-title":"Detection of Borrelia burgdorferi DNA in urine samples and cerebrospinal fluid samples from patients with early and late Lyme neuroborreliosis by polymerase chain reaction","volume":"30","author":"Lebech","year":"1992","journal-title":"J\u00a0Clin Microbiol"},{"issue":"105","key":"10.1016\/j.cll.2015.07.005_bib51","first-page":"1","article-title":"Polymerase chain reaction in diagnosis of Borrelia burgdorferi infections and studies on taxonomic classification","author":"Lebech","year":"2002","journal-title":"APMIS Suppl"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib52","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1469-0691.2010.03175.x","article-title":"Lyme borreliosis: clinical case definitions for diagnosis and management in Europe","volume":"17","author":"Stanek","year":"2011","journal-title":"Clin Microbiol Infect"},{"issue":"10","key":"10.1016\/j.cll.2015.07.005_bib53","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1128\/JCM.00410-08","article-title":"Validation of cultivation and PCR methods for diagnosis of Lyme neuroborreliosis","volume":"46","author":"Cerar","year":"2008","journal-title":"J\u00a0Clin Microbiol"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib54","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0002-9343(99)80097-7","article-title":"Bloodstream invasion in early Lyme disease: results from a prospective, controlled, blinded study using the polymerase chain reaction","volume":"99","author":"Goodman","year":"1995","journal-title":"Am J Med"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib55","first-page":"307","article-title":"Correlation of tests for detection of Borrelia burgdorferi sensu lato infection in patients with diagnosed borreliosis","volume":"13","author":"Chmielewska-Badora","year":"2006","journal-title":"Ann Agric Environ Med"},{"key":"10.1016\/j.cll.2015.07.005_bib56","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1086\/321911","article-title":"False-positive results of PCR testing for Lyme disease","volume":"33","author":"Molloy","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.cll.2015.07.005_bib57","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1128\/JCM.40.2.319-324.2002","article-title":"Laboratory testing for Lyme disease: possibilities and practicalities","volume":"40","author":"Reed","year":"2002","journal-title":"J\u00a0Clin Microbiol"},{"issue":"4","key":"10.1016\/j.cll.2015.07.005_bib58","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1056\/NEJM199401273300401","article-title":"Detection of Borrelia burgdorferi DNA\u00a0by polymerase chain reaction in synovial fluid from patients with Lyme arthritis","volume":"330","author":"Nocton","year":"1994","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.cll.2015.07.005_bib59","doi-asserted-by":"crossref","first-page":"487","DOI":"10.7326\/0003-4819-120-6-199403150-00007","article-title":"The persistence of spirochetal nucleic acids in active Lyme arthritis","volume":"120","author":"Bradley","year":"1994","journal-title":"Ann Intern Med"},{"issue":"3\u20134","key":"10.1016\/j.cll.2015.07.005_bib60","doi-asserted-by":"crossref","first-page":"205","DOI":"10.2119\/2007-00091.Rupprecht","article-title":"The pathogenesis of Lyme neuroborreliosis: from infection to inflammation","volume":"14","author":"Rupprecht","year":"2008","journal-title":"Mol Med"},{"issue":"9","key":"10.1016\/j.cll.2015.07.005_bib61","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1111\/j.1469-0691.2006.01509.x","article-title":"Evaluation of an internally controlled real-time PCR targeting the ospA gene for detection of Borrelia burgdorferi sensu lato DNA in cerebrospinal fluid","volume":"12","author":"Gooskens","year":"2006","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib62","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1574-695X.2006.00139.x","article-title":"Microbiological and serological diagnosis of Lyme borreliosis","volume":"49","author":"Wilske","year":"2007","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"3","key":"10.1016\/j.cll.2015.07.005_bib63","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1080\/00365549850160918","article-title":"Characterization of Borrelia burgdorferi strains in Lyme arthritis","volume":"30","author":"Eiffert","year":"1998","journal-title":"Scand J Infect Dis"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02112610","article-title":"Polymerase chain reaction for detection of Borrelia burgdorferi DNA in skin lesions of early and late Lyme borreliosis","volume":"14","author":"von Stedingk","year":"1995","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"10.1016\/j.cll.2015.07.005_bib65","first-page":"6","article-title":"Long term and repeated electron microscopy and PCR detection of Borrelia burgdorferi sensu lato after an antibiotic treatment","volume":"12","author":"Honegr","year":"2004","journal-title":"Cent Eur J Public Health"},{"issue":"10","key":"10.1016\/j.cll.2015.07.005_bib66","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1111\/j.1365-4632.2008.03709.x","article-title":"Examination of specific DNA by PCR in patients with different forms of Lyme borreliosis","volume":"47","author":"Picha","year":"2008","journal-title":"Int J Dermatol"}],"container-title":["Clinics in Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272271215000980?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272271215000980?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T20:22:01Z","timestamp":1599510121000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272271215000980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":66,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0272271215000980"],"URL":"https:\/\/doi.org\/10.1016\/j.cll.2015.07.005","relation":{},"ISSN":["0272-2712"],"issn-type":[{"value":"0272-2712","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alternatives to Serologic Testing for Diagnosis of Lyme Disease","name":"articletitle","label":"Article Title"},{"value":"Clinics in Laboratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cll.2015.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}