{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T23:43:34Z","timestamp":1780703014353,"version":"3.54.1"},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Laboratory Medicine"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.cll.2021.04.003","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T22:11:13Z","timestamp":1626991873000},"page":"405-416","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Update on Lymphoblastic Leukemia\/Lymphoma"],"prefix":"10.1016","volume":"41","author":[{"given":"Drago\u0219 C.","family":"Luca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cll.2021.04.003_bib1","series-title":"WHO classification of Tumours of haematopoietic and lymphoid tissues (revised 4th edition)","first-page":"199","article-title":"Precursor lymphoid neoplasms","author":"Borowitz","year":"2017"},{"key":"10.1016\/j.cll.2021.04.003_bib2","series-title":"Hematopathology","first-page":"761","article-title":"Precursor B- and T-cell neoplasms","author":"Duffield","year":"2017"},{"key":"10.1016\/j.cll.2021.04.003_bib3","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/S0140-6736(19)33018-1","article-title":"Acute lymphoblastic leukemia","volume":"395","author":"Malard","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.cll.2021.04.003_bib4","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.critrevonc.2017.03.020","article-title":"Lymphoblastic lymphoma","volume":"113","author":"Cortelazzo","year":"2017","journal-title":"Crit Rev Oncol Hematol"},{"issue":"2","key":"10.1016\/j.cll.2021.04.003_bib5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11899-020-00582-5","article-title":"MLL-rearranged acute lymphoblastic leukemia","volume":"15","author":"El Chaer","year":"2020","journal-title":"Curr Hematol Malig Rep"},{"issue":"19","key":"10.1016\/j.cll.2021.04.003_bib6","doi-asserted-by":"crossref","first-page":"3385","DOI":"10.1182\/blood-2013-08-524124","article-title":"GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL","volume":"122","author":"Walsh","year":"2013","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.cll.2021.04.003_bib7","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1182\/asheducation-2016.1.561","article-title":"Ph-like acute lymphoblastic leukemia","volume":"2016","author":"Tran","year":"2016","journal-title":"Hematol Am Soc Hematol Educ Program"},{"key":"10.1016\/j.cll.2021.04.003_bib8","doi-asserted-by":"crossref","first-page":"150","DOI":"10.5858\/arpa.2019-0194-RA","article-title":"BCR-ABL1-like B-acute lymphoblastic leukemia\/lymphoma: a comprehensive review","volume":"144","author":"Jain","year":"2020","journal-title":"Arch Pathol Lab Med"},{"issue":"11","key":"10.1016\/j.cll.2021.04.003_bib9","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJMoa1403088","article-title":"Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia","volume":"371","author":"Roberts","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"25","key":"10.1016\/j.cll.2021.04.003_bib10","doi-asserted-by":"crossref","first-page":"3352","DOI":"10.1182\/blood-2016-12-758979","article-title":"Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group","volume":"129","author":"Reshmi","year":"2017","journal-title":"Blood"},{"issue":"12","key":"10.1016\/j.cll.2021.04.003_bib11","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1182\/blood-2017-05-742643","article-title":"New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia","volume":"130","author":"Lilljebj\u00f6rn","year":"2017","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.cll.2021.04.003_bib12","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/s41588-018-0315-5","article-title":"PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia","volume":"51","author":"Gu","year":"2019","journal-title":"Nat Genet"},{"issue":"12","key":"10.1016\/j.cll.2021.04.003_bib13","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1200\/JCO.2017.74.3617","article-title":"IKZF1plus defines a new minimal residual disease-dependent very-poor prognostic profile in pediatric B-cell precursor acute lymphoblastic leukemia","volume":"36","author":"Stanulla","year":"2018","journal-title":"J\u00a0Clin Oncol"}],"container-title":["Clinics in Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272271221000214?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272271221000214?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T23:57:20Z","timestamp":1759449440000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272271221000214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S0272271221000214"],"URL":"https:\/\/doi.org\/10.1016\/j.cll.2021.04.003","relation":{},"ISSN":["0272-2712"],"issn-type":[{"value":"0272-2712","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Update on Lymphoblastic Leukemia\/Lymphoma","name":"articletitle","label":"Article Title"},{"value":"Clinics in Laboratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cll.2021.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}