{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T10:35:13Z","timestamp":1742380513060,"version":"3.28.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","clinical-lung-cancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Lung Cancer"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.cllc.2024.08.005","type":"journal-article","created":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T17:23:18Z","timestamp":1723569798000},"page":"690-698.e2","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Prophylactic Cranial Irradiation in Early to Mid-stage Small Cell Lung Cancer Patients in the Era of Magnetic Resonance Imaging"],"prefix":"10.1016","volume":"25","author":[{"given":"Jianjiang","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongru","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.cllc.2024.08.005_bib0001","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jtho.2016.09.133","article-title":"Prophylactic cranial irradiation for patients with surgically resected small cell lung cancer","volume":"12","author":"Xu","year":"2017","journal-title":"J Thorac Oncol"},{"issue":"1","key":"10.1016\/j.cllc.2024.08.005_bib0002","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.radonc.2017.07.019","article-title":"Patterns of failure in limited-stage small cell lung cancer: Implications of TNM stage for prophylactic cranial irradiation","volume":"125","author":"Wu","year":"2017","journal-title":"Radiother Oncol"},{"issue":"2","key":"10.1016\/j.cllc.2024.08.005_bib0003","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.cllc.2017.08.004","article-title":"Prophylactic cranial irradiation for resectable small-cell lung cancer","volume":"19","author":"Halthore","year":"2018","journal-title":"Clin Lung Cancer"},{"key":"10.1016\/j.cllc.2024.08.005_bib0004","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/1748-717X-9-216","article-title":"Risk factors for brain metastases in completely resected small cell lung cancer: a retrospective study to identify patients most likely to benefit from prophylactic cranial irradiation","volume":"9","author":"Zhu","year":"2014","journal-title":"Radiat Oncol"},{"issue":"1","key":"10.1016\/j.cllc.2024.08.005_bib0005","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.ijrobp.2012.03.038","article-title":"Factors affecting the risk of brain metastasis in small cell lung cancer with surgery: is prophylactic cranial irradiation necessary for stage I-III disease?","volume":"85","author":"Gong","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"6","key":"10.1016\/j.cllc.2024.08.005_bib0006","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1111\/1754-9485.13269","article-title":"Prophylactic cranial irradiation confers favourable prognosis for patients with limited-stage small cell lung cancer in the era of MRI: a propensity score-matched analysis","volume":"65","author":"Li","year":"2021","journal-title":"J Med Imaging Radiat Oncol"},{"issue":"7","key":"10.1016\/j.cllc.2024.08.005_bib0007","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJM199908123410703","article-title":"Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic cranial irradiation overview collaborative group","volume":"341","author":"Aup\u00e9rin","year":"1999","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1016\/j.cllc.2024.08.005_bib0008","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1093\/annonc\/mdq576","volume":"22","author":"Le P\u00e9choux","year":"2011","journal-title":"Ann Oncol"},{"issue":"28","key":"10.1016\/j.cllc.2024.08.005_bib0009","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1200\/JCO.21.00639","article-title":"Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer (PREMER): a GICOR-GOECP-SEOR study","volume":"39","author":"Rodr\u00edguez de Dios","year":"2021","journal-title":"J Clin Oncol"},{"issue":"5","key":"10.1016\/j.cllc.2024.08.005_bib0010","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.jtho.2020.12.024","article-title":"Phase 3 randomized trial of prophylactic cranial irradiation with or without hippocampus avoidance in SCLC (NCT01780675)","volume":"16","author":"Belderbos","year":"2021","journal-title":"J Thorac Oncol"},{"issue":"2","key":"10.1016\/j.cllc.2024.08.005_bib0011","doi-asserted-by":"crossref","first-page":"433","DOI":"10.7150\/jca.21465","article-title":"Prophylactic cranial irradiation in resected small cell lung cancer: a systematic review with meta-analysis","volume":"9","author":"Yang","year":"2018","journal-title":"J Cancer"},{"issue":"446","key":"10.1016\/j.cllc.2024.08.005_bib0012","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"Proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"Publications of the American Statistical Association"},{"key":"10.1016\/j.cllc.2024.08.005_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.833478","article-title":"Benefits of prophylactic cranial irradiation in the MRI era for patients with limited stage small cell lung cancer","volume":"12","author":"Qi","year":"2022","journal-title":"Front Oncol"},{"issue":"4","key":"10.1016\/j.cllc.2024.08.005_bib0014","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.1929","article-title":"Rates of overall survival and intracranial control in the magnetic resonance imaging era for patients with limited-stage small cell lung cancer with and without prophylactic cranial irradiation","volume":"3","author":"Pezzi","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"3","key":"10.1016\/j.cllc.2024.08.005_bib0015","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/0284186X.2023.2196368","article-title":"Survival benefit of prophylactic cranial irradiation in limited-stage small-cell lung cancer in modern magnetic resonance imaging staging: a systematic review and meta-analysis","volume":"62","author":"Liu","year":"2023","journal-title":"Acta Oncol"},{"issue":"8","key":"10.1016\/j.cllc.2024.08.005_bib0016","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s00066-023-02073-x","article-title":"A nomogram to predict the cumulative risk for brain metastases in patients with limited-stage small cell lung cancer without prophylactic cranial irradiation","volume":"199","author":"Liu","year":"2023","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.cllc.2024.08.005_bib0017","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.2147\/CMAR.S175043","article-title":"Clinical value of carcinoembryonic antigen for predicting the incidence of brain metastases and survival in small cell lung cancer patients treated with prophylactic cranial irradiation","volume":"10","author":"Guo","year":"2018","journal-title":"Cancer Manag Res"},{"issue":"19","key":"10.1016\/j.cllc.2024.08.005_bib0018","doi-asserted-by":"crossref","first-page":"4906","DOI":"10.3390\/cancers14194906","article-title":"Construction of brain metastasis prediction model and optimization of prophylactic cranial irradiation selection for limited-stage small-cell lung cancer","volume":"14","author":"Hou","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"2","key":"10.1016\/j.cllc.2024.08.005_bib0019","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.cllc.2018.11.013","article-title":"Prognostic significance of total lymphocyte count, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio in limited-stage small-cell lung cancer","volume":"20","author":"Suzuki","year":"2019","journal-title":"Clin Lung Cancer"},{"issue":"5","key":"10.1016\/j.cllc.2024.08.005_bib0020","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/crj.13615","article-title":"Development and validation of a nomogram for the prediction of brain metastases in small cell lung cancer","volume":"17","author":"Li","year":"2023","journal-title":"Clin Respir J"},{"issue":"12","key":"10.1016\/j.cllc.2024.08.005_bib0021","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1007\/s00066-018-1362-7","article-title":"Risk factors for brain metastasis in patients with small cell lung cancer without prophylactic cranial irradiation","volume":"194","author":"Zheng","year":"2018","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.cllc.2024.08.005_bib0022","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.radonc.2020.01.009","article-title":"Risk stratification of symptomatic brain metastases by clinical and FDG PET parameters for selective use of prophylactic cranial irradiation in patients with extensive disease of small cell lung cancer","volume":"143","author":"Chung","year":"2020","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.cllc.2024.08.005_bib0023","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.882744","article-title":"A New nomogram and risk stratification of brain metastasis by clinical and inflammatory parameters in stage III small cell lung cancer without prophylactic cranial irradiation","volume":"12","author":"Qiu","year":"2022","journal-title":"Front Oncol"},{"key":"10.1016\/j.cllc.2024.08.005_bib0024","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.2147\/CMAR.S347449","article-title":"Factors affecting the risk of brain metastasis in limited-stage small cell lung cancer after prophylactic cranial irradiation","volume":"14","author":"Chen","year":"2022","journal-title":"Cancer Manag Res"},{"issue":"5","key":"10.1016\/j.cllc.2024.08.005_bib0025","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.0103","article-title":"Association of twice-daily radiotherapy with subsequent brain metastases in adults with small cell lung cancer","volume":"2","author":"Zeng","year":"2019","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.cllc.2024.08.005_bib0026","doi-asserted-by":"crossref","first-page":"10131","DOI":"10.2147\/IJGM.S342009","article-title":"Brain metastasis in patients with small cell lung cancer","volume":"14","author":"Li","year":"2021","journal-title":"Int J Gen Med"},{"issue":"4","key":"10.1016\/j.cllc.2024.08.005_bib0027","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1097\/JTO.0b013e31820d782d","article-title":"Selecting patients with extensive-stage small cell lung cancer for prophylactic cranial irradiation by predicting brain metastases","volume":"6","author":"Greenspoon","year":"2011","journal-title":"J Thorac Oncol"},{"issue":"3","key":"10.1016\/j.cllc.2024.08.005_bib0028","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.radonc.2018.05.026","article-title":"Hematologic variables associated with brain failure in patients with small-cell lung cancer","volume":"128","author":"Suzuki","year":"2018","journal-title":"Radiother Oncol"},{"issue":"1","key":"10.1016\/j.cllc.2024.08.005_bib0029","doi-asserted-by":"crossref","first-page":"e13730","DOI":"10.1111\/crj.13730","article-title":"Construction of brain metastasis prediction model in limited stage small cell lung cancer patients without prophylactic cranial irradiation","volume":"18","author":"Guo","year":"2024","journal-title":"Clin Respir J"},{"issue":"5","key":"10.1016\/j.cllc.2024.08.005_bib0030","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S1470-2045(17)30230-9","article-title":"Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial","volume":"18","author":"Takahashi","year":"2017","journal-title":"Lancet Oncol"}],"container-title":["Clinical Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525730424001608?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525730424001608?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T23:47:13Z","timestamp":1732319233000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525730424001608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S1525730424001608"],"URL":"https:\/\/doi.org\/10.1016\/j.cllc.2024.08.005","relation":{},"ISSN":["1525-7304"],"issn-type":[{"type":"print","value":"1525-7304"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of Prophylactic Cranial Irradiation in Early to Mid-stage Small Cell Lung Cancer Patients in the Era of Magnetic Resonance Imaging","name":"articletitle","label":"Article Title"},{"value":"Clinical Lung Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cllc.2024.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}