{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:08:54Z","timestamp":1791950934769,"version":"4.3.4"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinical-lymphoma-myeloma-leukemia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Lymphoma Myeloma and Leukemia"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.clml.2016.09.003","type":"journal-article","created":{"date-parts":[[2016,9,17]],"date-time":"2016-09-17T18:45:31Z","timestamp":1474137931000},"page":"46-51","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Acute Leukemia Characteristics are Different Around the World: the Mexican Perspective"],"prefix":"10.1016","volume":"17","author":[{"given":"David","family":"G\u00f3mez-Almaguer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edson Ren\u00e9","family":"Marcos-Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efreen Horacio","family":"Monta\u00f1o-Figueroa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo J.","family":"Ruiz-Arg\u00fcelles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Roberto","family":"Best-Aguilera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda del Carmen","family":"L\u00f3pez-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esperanza","family":"Barrera-Chairez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"L\u00f3pez-Arrollo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Omar","family":"Ramos-Pe\u00f1afiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"Le\u00f3n-Pe\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u00edas Eugenio","family":"Gonz\u00e1lez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perla Edith","family":"Rivas-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto","family":"Tellez-Hinojosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"G\u00f3mez-De Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos","family":"Jaime-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clml.2016.09.003_bib1","first-page":"109","article-title":"Epidemiolog\u00eda de las neoplasias hemato-oncol\u00f3gicas","volume":"2","author":"Tirado","year":"2007","journal-title":"Cancerolog\u00eda"},{"key":"10.1016\/j.clml.2016.09.003_bib2","first-page":"252","article-title":"Cancer treatment and survivorship statistics, 2014","volume":"64","author":"DeSantis","year":"2014","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.clml.2016.09.003_bib3","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1586\/14737140.3.3.311","article-title":"The burden and outcomes associated with four leukemias: AML, ALL, CLL and CML","volume":"3","author":"Redaelli","year":"2003","journal-title":"Expert Rev Anticancer Ther"},{"key":"10.1016\/j.clml.2016.09.003_bib4","series-title":"Cancer Facts & Statistics","year":"2016"},{"key":"10.1016\/j.clml.2016.09.003_bib5","series-title":"Sistema Nacional de Informaci\u00f3n en Salud (SINAIS): Defunction database system","author":"Direcci\u00f3n General de Informaci\u00f3n en Salud (DGIS)","year":"2012"},{"key":"10.1016\/j.clml.2016.09.003_bib6","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1182\/blood-2011-04-347872","article-title":"Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007","volume":"119","author":"Dores","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib7","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1182\/blood-2012-06-437343","article-title":"Race and ethnicity in decisions about unrelated hematopoietic stem cell donation","volume":"121","author":"Switzer","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib8","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1046\/j.1365-2141.2003.04480.x","article-title":"Acute promyelocytic leukaemia in patients originating in Latin America is associated with an increased frequency of the bcr1 subtype of the PML\/RARa fusion gene","volume":"122","author":"Douer","year":"2003","journal-title":"Br J Haematol"},{"key":"10.1016\/j.clml.2016.09.003_bib9","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.blre.2010.10.002","article-title":"Independent prognostic variables in acute myeloid leukaemia","volume":"25","author":"Smith","year":"2011","journal-title":"Blood Rev"},{"key":"10.1016\/j.clml.2016.09.003_bib10","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1054\/bjoc.2000.1504","volume":"83","author":"Donadieu","year":"2000","journal-title":"Br J Cancer"},{"key":"10.1016\/j.clml.2016.09.003_bib11","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1182\/blood.V75.1.174.174","article-title":"Heterogeneity of presenting features and their relation to treatment outcome in 120 children with T-cell acute lymphoblastic leukemia","volume":"75","author":"Pui","year":"1990","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib12","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/tropej\/46.6.338","article-title":"Age, sex, haemoglobin level, and white cell count at diagnosis are important prognostic factors in children with acute lymphoblastic leukemia treated with BFM-type protocol","volume":"46","author":"Ng","year":"2000","journal-title":"J\u00a0Trop Pediatr"},{"key":"10.1016\/j.clml.2016.09.003_bib13","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1182\/blood.V60.3.677.677","article-title":"Adolescent and adult acute lymphoblastic leukemia: prognostic features and outcome of therapy. A study of 293 patients","volume":"60","author":"Baccarani","year":"1982","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib14","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/cyto.b.20083","article-title":"Meeting report on the second Latin American consensus conference for flow cytometric immunophenotyping of hematological malignancies","volume":"70","author":"Ruiz-Arg\u00fcelles","year":"2006","journal-title":"Cytometry B Clin Cytom"},{"key":"10.1016\/j.clml.2016.09.003_bib15","first-page":"167","article-title":"Frecuencia de leucemias agudas en un hospital de referencia","volume":"50","author":"Gonz\u00e1lez-Salas","year":"2012","journal-title":"Rev Med Inst Mex Seguro Soc"},{"key":"10.1016\/j.clml.2016.09.003_bib16","first-page":"9","article-title":"Epidemiolog\u00eda de las leucemias en Bolivia: 1473 casos Enero 1999 a Mayo de 2012","volume":"18","author":"Amaru","year":"2012","journal-title":"Rev M\u00e9d La Paz"},{"key":"10.1016\/j.clml.2016.09.003_bib17","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1002\/cncr.11316","article-title":"Trends in leukemia incidence and survival in the United States (1973-1998)","volume":"97","author":"Xie","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2016.09.003_bib18","article-title":"Acute leukemia in adult Hispanic Americans: differences in incidence rates by nativity","volume":"1","author":"Pollyea","year":"2014","journal-title":"J\u00a0Cancer Prev Curr Res"},{"key":"10.1016\/j.clml.2016.09.003_bib19","doi-asserted-by":"crossref","first-page":"5312","DOI":"10.1182\/blood-2009-09-245944","article-title":"Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic\/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia","volume":"115","author":"Harvey","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1182\/blood.V71.1.123.123","article-title":"Prognostic factors in a multicenter study for treatment of acute lymphoblastic leukemia in adults","volume":"71","author":"Hoelzer","year":"1988","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib21","doi-asserted-by":"crossref","first-page":"3189","DOI":"10.1182\/blood-2006-10-051912","article-title":"Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII\/Eastern Cooperative Oncology Group (ECOG) 2993 trial","volume":"109","author":"Moorman","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib22","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1038\/leu.2012.26","article-title":"Newly diagnosed acute lymphoblastic leukemia in China (I): abnormal genetic patterns in 1346 childhood and adult cases and their comparison with the reports from Western countries","volume":"26","author":"Chen","year":"2012","journal-title":"Leukemia"},{"key":"10.1016\/j.clml.2016.09.003_bib23","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3324\/haematol.2012.063602","article-title":"Recent trends in survival of adult patients with acute leukemia: overall improvements, but persistent and partly increasing disparity in survival of patients from minority groups","volume":"98","author":"Pulte","year":"2013","journal-title":"Haematologica"},{"key":"10.1016\/j.clml.2016.09.003_bib24","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/bjh.13406","article-title":"Acute myeloid leukaemia: challenges and real world data from India","volume":"170","author":"Philip","year":"2015","journal-title":"Br J Haematol"},{"key":"10.1016\/j.clml.2016.09.003_bib25","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/annonc\/mdg169","article-title":"Cancer prevalence in the UK: results from the EUROPREVAL study","volume":"14","author":"Forman","year":"2003","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clml.2016.09.003_bib26","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1600-0609.1998.tb01096.x","article-title":"Acute promyelocytic leukaemia: epidemiology and risk factors. A report of the GIMEMA Italian archive of adult acute leukaemia","volume":"61","author":"Pulsoni","year":"1998","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.clml.2016.09.003_bib27","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.bjhh.2014.11.008","article-title":"Acute myeloid leukemia: survival analysis of patients at a university hospital of Paran\u00e1","volume":"37","author":"Lunardon-Padilha","year":"2014","journal-title":"Rev Bras Hematol Hemoter"},{"key":"10.1016\/j.clml.2016.09.003_bib28","first-page":"100","article-title":"Experiencia del INCMNSZ en pacientes adultos con leucemia mieloide aguda. Cohorte 2003-2008","volume":"62","author":"Buitr\u00f3n-Santiago","year":"2010","journal-title":"Rev Invest Clin"},{"key":"10.1016\/j.clml.2016.09.003_bib29","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1159\/000356794","article-title":"Characteristics and clinical evolution of patients with acute myeloblastic leukemia in northeast Mexico: an eight-year experience at a university hospital","volume":"132","author":"Jaime-P\u00e9rez","year":"2014","journal-title":"Acta Haematol"},{"key":"10.1016\/j.clml.2016.09.003_bib30","doi-asserted-by":"crossref","first-page":"26","DOI":"10.59566\/IJBS.2013.9026","article-title":"Cytogenetic profile of de novo acute myeloid leukemia patients in Malaysia","volume":"9","author":"Meng","year":"2013","journal-title":"Int J Biomed Sci"},{"key":"10.1016\/j.clml.2016.09.003_bib31","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1002\/cncr.22233","article-title":"Acute myeloid leukemia: epidemiology and etiology","volume":"107","author":"Deschler","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2016.09.003_bib32","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1590\/S0100-879X2003000300007","article-title":"Acute leukemias in Piau\u00ed: comparison with features observed in other regions of Brazil","volume":"36","author":"Rego","year":"2003","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.clml.2016.09.003_bib33","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/ajh.23858","article-title":"Improving outcomes for patients with acute myeloid leukemia in first relapse: a single center experience","volume":"90","author":"Pemajaru","year":"2015","journal-title":"Am J Hematol"},{"key":"10.1016\/j.clml.2016.09.003_bib34","doi-asserted-by":"crossref","first-page":"4162","DOI":"10.1002\/cncr.28342","article-title":"Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent\/young adult and younger patients: a report from the Children\u2019s Oncology Group","volume":"119","author":"Canner","year":"2013","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2016.09.003_bib35","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.clml.2015.12.010","article-title":"Patient characteristics and outcomes in adolescents and young adults (AYA) with acute myeloid leukemia (AML)","volume":"16","author":"Pemmaraju","year":"2016","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"10.1016\/j.clml.2016.09.003_bib36","doi-asserted-by":"crossref","first-page":"4170","DOI":"10.1002\/cncr.28344","article-title":"Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials","volume":"119","author":"Woods","year":"2013","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2016.09.003_bib37","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1002\/cncr.30129","article-title":"Childhood leukemia incidence in California: high and rising in the Hispanic population","volume":"122","author":"Giddings","year":"2016","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2016.09.003_bib38","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/S1470-2045(15)00218-1","article-title":"Progress and remaining challenges for cancer control in Latin America and the Caribbean","volume":"16","author":"Strasser-Weippl","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clml.2016.09.003_bib39","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/COC.0b013e31828d7536","article-title":"Age and genetics: how do prognostic factors explain disparities in acute myeloid leukemia?","volume":"38","author":"Patel","year":"2015","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.clml.2016.09.003_bib40","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1182\/blood.V89.1.348","article-title":"Promyelocytic leukemia in Mexican Mestizos","volume":"89","author":"Ruiz-Arg\u00fcelles","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib41","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1182\/blood.V87.1.308.308","article-title":"High frequency of acute promyelocytic leukemia among Latinos with acute myeloid leukemia","volume":"87","author":"Douer","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib42","doi-asserted-by":"crossref","first-page":"437","DOI":"10.4103\/0377-4929.42555","article-title":"Does acute promyelocytic leukemia in Indian patients have biology different from the West?","volume":"51","author":"Dutta","year":"2008","journal-title":"Indian J Pathol Microbiol"},{"issue":"Suppl 2","key":"10.1016\/j.clml.2016.09.003_bib43","doi-asserted-by":"crossref","first-page":"S151","DOI":"10.21149\/spm.v55s2.5111","article-title":"Prevalence of obesity in Mexican adults, 2000-2012","volume":"55","author":"Barquera","year":"2013","journal-title":"Salud Publica Mex"},{"key":"10.1016\/j.clml.2016.09.003_bib44","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1038\/sj.leu.2400783","article-title":"Association between increased body mass index and a diagnosis of acute promyelocytic leukemia in patients with acute myeloid leukemia","volume":"11","author":"Estey","year":"1997","journal-title":"Leukemia"},{"key":"10.1016\/j.clml.2016.09.003_bib45","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/2040620711408490","article-title":"High prevalence of obesity in acute promyelocytic leukemia (APL): implications for differentiating agents in APL and metabolic syndrome","volume":"2","author":"Tedesco","year":"2011","journal-title":"Ther Adv Hematol"},{"key":"10.1016\/j.clml.2016.09.003_bib46","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1200\/JCO.1987.5.9.1364","article-title":"Hyperleukocytosis in adult acute nonlymphocytic leukemia: impact on remission rate and duration, and survival","volume":"5","author":"Dutcher","year":"1987","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clml.2016.09.003_bib47","first-page":"1247","article-title":"Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups","volume":"96","author":"Sanz","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.clml.2016.09.003_bib48","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.3324\/haematol.2011.040592","article-title":"Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: relevance of mutated NPM1 and FLT3-ITD","volume":"96","author":"De Jonge","year":"2011","journal-title":"Haematologica"}],"container-title":["Clinical Lymphoma Myeloma and Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265016305596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265016305596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:27:55Z","timestamp":1761870475000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2152265016305596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S2152265016305596"],"URL":"https:\/\/doi.org\/10.1016\/j.clml.2016.09.003","relation":{},"ISSN":["2152-2650"],"issn-type":[{"value":"2152-2650","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute Leukemia Characteristics are Different Around the World: the Mexican Perspective","name":"articletitle","label":"Article Title"},{"value":"Clinical Lymphoma Myeloma and Leukemia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clml.2016.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}