{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:19:43Z","timestamp":1791584383513,"version":"4.3.4"},"reference-count":50,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinical-lymphoma-myeloma-leukemia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Lymphoma Myeloma and Leukemia"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.clml.2017.02.027","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T07:17:32Z","timestamp":1488871052000},"page":"263-267","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":226,"title":["Myeloid Sarcoma: Presentation, Diagnosis, and Treatment"],"prefix":"10.1016","volume":"17","author":[{"given":"L. Max","family":"Almond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Charalampakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel J.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Gourevitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anant","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clml.2017.02.027_bib1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1309\/AJCPO58YWIBUBESX","article-title":"Extramedullary manifestations of myeloid neoplasms","volume":"144","author":"Wilson","year":"2015","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib2","doi-asserted-by":"crossref","first-page":"5019","DOI":"10.1182\/blood-2011-01-293050","article-title":"The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications","volume":"117","author":"Campo","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.clml.2017.02.027_bib3","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1002\/1097-0142(19810915)48:6<1426::AID-CNCR2820480626>3.0.CO;2-G","article-title":"Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases","volume":"48","author":"Neiman","year":"1981","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2017.02.027_bib4","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1309\/AJCP1ZA7HYZKAZHS","article-title":"Myeloid sarcoma: extramedullary manifestation of myeloid disorders","volume":"132","author":"Campidelli","year":"2009","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib5","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1097\/PAS.0000000000000727","article-title":"Clinicopathological, cytogenetic, and prognostic analysis of 131 myeloid sarcoma patients","volume":"40","author":"Kawamoto","year":"2016","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib6","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/1097-0142(197304)31:4<948::AID-CNCR2820310428>3.0.CO;2-N","article-title":"Autopsy study of granulocytic sarcoma (chloroma) in patients with myelogenous leukemia, Hiroshima-Nagasaki 1949-1969","volume":"31","author":"Liu","year":"1973","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2017.02.027_bib7","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s13238-013-3057-2","article-title":"The evolving landscape in the therapy of acute myeloid leukemia","volume":"4","author":"Peloquin","year":"2013","journal-title":"Protein Cell"},{"key":"10.1016\/j.clml.2017.02.027_bib8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s11899-014-0199-0","article-title":"Novel therapeutics in acute myeloid leukemia","volume":"9","author":"Sweet","year":"2014","journal-title":"Curr Hematol Malig Rep"},{"key":"10.1016\/j.clml.2017.02.027_bib9","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1148\/radiology.190.3.8115614","article-title":"Granulocytic sarcoma in childhood leukemia: imaging features","volume":"190","author":"Pui","year":"1994","journal-title":"Radiology"},{"key":"10.1016\/j.clml.2017.02.027_bib10","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.3324\/haematol.2011.045047","article-title":"(1)(8)F-FDG-PET\/CT for detection of extramedullary acute myeloid leukemia","volume":"96","author":"Stolzel","year":"2011","journal-title":"Haematologica"},{"key":"10.1016\/j.clml.2017.02.027_bib11","doi-asserted-by":"crossref","first-page":"3785","DOI":"10.1182\/blood-2011-04-347229","article-title":"How I treat extramedullary acute myeloid leukemia","volume":"118","author":"Bakst","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.clml.2017.02.027_bib12","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1111\/cup.12231","article-title":"Aleukemic cutaneous myeloid sarcoma","volume":"40","author":"Aboutalebi","year":"2013","journal-title":"J\u00a0Cutan Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib13","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1002\/1097-0142(19861215)58:12<2697::AID-CNCR2820581225>3.0.CO;2-R","article-title":"Granulocytic sarcoma in nonleukemic patients","volume":"58","author":"Meis","year":"1986","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2017.02.027_bib14","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.biopha.2012.10.014","article-title":"Is there a \u201cgold\u201d standard treatment for patients with isolated myeloid sarcoma?","volume":"67","author":"Antic","year":"2013","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.clml.2017.02.027_bib15","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1002\/cncr.10399","article-title":"Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature","volume":"94","author":"Yamauchi","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2017.02.027_bib16","first-page":"790","article-title":"Extramedullary myeloid cell tumors. An immunohistochemical study of 29 cases using routinely fixed and processed paraffin-embedded tissue sections","volume":"119","author":"Roth","year":"1995","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.clml.2017.02.027_bib17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.anndiagpath.2014.06.001","article-title":"A\u00a0practical approach to diagnose soft tissue myeloid sarcoma preceding or coinciding with acute myeloid leukemia","volume":"18","author":"Seifert","year":"2014","journal-title":"Ann Diagn Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib18","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1080\/10428190600881231","article-title":"Megakaryoblastic differentiation of myeloid sarcoma in a patient with essential thrombocythemia","volume":"47","author":"Famoso","year":"2006","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.clml.2017.02.027_bib19","doi-asserted-by":"crossref","first-page":"287","DOI":"10.5144\/0256-4947.2001.287","article-title":"The value of CD34, myeloperoxidase and chloroacetate esterase (Leder) stain in the diagnosis of granulocytic sarcoma","volume":"21","author":"Mourad","year":"2001","journal-title":"Ann Saudi Med"},{"key":"10.1016\/j.clml.2017.02.027_bib20","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1111\/j.1600-0560.2011.01809.x","article-title":"Use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma","volume":"38","author":"Amador-Ortiz","year":"2011","journal-title":"J\u00a0Cutan Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib21","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/sj.leu.2404491","article-title":"Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients","volume":"21","author":"Pileri","year":"2007","journal-title":"Leukemia"},{"key":"10.1016\/j.clml.2017.02.027_bib22","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1097\/00000478-199310000-00006","article-title":"Extramedullary myeloid cell tumors. An immunohistochemical and morphologic study of 28 cases","volume":"17","author":"Traweek","year":"1993","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.clml.2017.02.027_bib23","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1755-7682-4-3","article-title":"Granulocytic sarcoma of the small bowel, greater omentum and peritoneum associated with a CBFbeta\/MYH11 fusion and inv(16) (p13q22): a case report","volume":"4","author":"Alvarez","year":"2011","journal-title":"Int Arch Med"},{"key":"10.1016\/j.clml.2017.02.027_bib24","first-page":"342","article-title":"Granulocytic sarcoma of abdomen in an acute myeloid leukemia patient with inv(16) and t(6;17) chromosome abnormalities: a case report and literature review","volume":"32","author":"Li","year":"2011","journal-title":"Zhonghua Xue Ye Xue Za Zhi"},{"key":"10.1016\/j.clml.2017.02.027_bib25","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.leukres.2010.01.009","article-title":"Granulocytic sarcoma of abdomen in acute myeloid leukemia patient with inv(16) and t(6;17) abnormal chromosome: case report and review of literature","volume":"34","author":"Zhang","year":"2010","journal-title":"Leuk Res"},{"key":"10.1016\/j.clml.2017.02.027_bib26","doi-asserted-by":"crossref","first-page":"e217","DOI":"10.1016\/j.clml.2014.06.027","article-title":"Isolated mesenteric CD20-positive myeloid sarcoma","volume":"14","author":"Ohanian","year":"2014","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"10.1016\/j.clml.2017.02.027_bib27","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.3109\/10428194.2014.963080","article-title":"Presentation and outcomes among patients with isolated myeloid sarcoma: a Surveillance, Epidemiology, and End Results database analysis","volume":"56","author":"Movassaghian","year":"2015","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.clml.2017.02.027_bib28","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1172\/JCI7615","article-title":"The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow","volume":"104","author":"Peled","year":"1999","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.clml.2017.02.027_bib29","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1084\/jem.187.5.753","article-title":"B\u00a0lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement","volume":"187","author":"Bleul","year":"1998","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.clml.2017.02.027_bib30","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1093\/annonc\/mdh268","article-title":"CD56+ hematological neoplasms presenting in the skin: a retrospective analysis of 23 new cases and 130 cases from the literature","volume":"15","author":"Bekkenk","year":"2004","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clml.2017.02.027_bib31","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000253592","article-title":"Prognostic factors of treatment outcomes in patients with granulocytic sarcoma","volume":"122","author":"Lan","year":"2009","journal-title":"Acta Haematol"},{"key":"10.1016\/j.clml.2017.02.027_bib32","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1097\/00043426-200310000-00004","article-title":"Extramedullary leukemia in children with newly diagnosed acute myeloid leukemia: a report from the Children's Cancer Group","volume":"25","author":"Dusenbery","year":"2003","journal-title":"J\u00a0Pediatr Hematol Oncol"},{"key":"10.1016\/j.clml.2017.02.027_bib33","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1002\/cncr.23691","article-title":"Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia","volume":"113","author":"Tsimberidou","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.clml.2017.02.027_bib34","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/hon.994","article-title":"Clinical implications of acute myeloid leukemia presenting as myeloid sarcoma","volume":"30","author":"Avni","year":"2012","journal-title":"Hematol Oncol"},{"key":"10.1016\/j.clml.2017.02.027_bib35","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00280-003-0671-3","article-title":"Mylotarg, fludarabine, cytarabine (ara-C), and cyclosporine (MFAC) regimen as post-remission therapy in acute myelogenous leukemia","volume":"52","author":"Tsimberidou","year":"2003","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1016\/j.clml.2017.02.027_bib36","doi-asserted-by":"crossref","first-page":"351","DOI":"10.7326\/0003-4819-123-5-199509010-00005","article-title":"Isolated chloroma: the effect of early antileukemic therapy","volume":"123","author":"Imrie","year":"1995","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.clml.2017.02.027_bib37","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1080\/10428190290012056","article-title":"Isolated myelosarcoma in children\u2014update and review","volume":"43","author":"Reinhardt","year":"2002","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.clml.2017.02.027_bib38","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1016\/j.ijrobp.2011.02.057","article-title":"Radiation therapy for chloroma (granulocytic sarcoma)","volume":"82","author":"Bakst","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clml.2017.02.027_bib39","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1084\/jem.184.3.1101","article-title":"A\u00a0highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)","volume":"184","author":"Bleul","year":"1996","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.clml.2017.02.027_bib40","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1101\/gad.13.22.2905","article-title":"Cellular survival: a play in three Akts","volume":"13","author":"Datta","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/j.clml.2017.02.027_bib41","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.286.5443.1309","article-title":"Perspectives: signal transduction. Cell survival demands some Rsk","volume":"286","author":"Nebreda","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.clml.2017.02.027_bib42","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1046\/j.1365-2141.2001.03164.x","article-title":"High expression of the chemokine receptor CXCR4 predicts extramedullary organ infiltration in childhood acute lymphoblastic leukaemia","volume":"115","author":"Crazzolara","year":"2001","journal-title":"Br J Haematol"},{"key":"10.1016\/j.clml.2017.02.027_bib43","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1084\/jem.185.1.111","article-title":"The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood","volume":"185","author":"Aiuti","year":"1997","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.clml.2017.02.027_bib44","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/MAJ.0b013e31829ca859","article-title":"Clinical characteristics and prognosis of nonleukemic myeloid sarcoma","volume":"347","author":"He","year":"2014","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.clml.2017.02.027_bib45","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.3324\/haematol.2011.041418","article-title":"Allogeneic hematopoietic stem cell transplantation for isolated and leukemic myeloid sarcoma in adults: a report from the Acute Leukemia Working Party of the European group for Blood and Marrow Transplantation","volume":"96","author":"Chevallier","year":"2011","journal-title":"Haematologica"},{"key":"10.1016\/j.clml.2017.02.027_bib46","doi-asserted-by":"crossref","first-page":"4940","DOI":"10.1200\/JCO.2007.15.6315","article-title":"Allogeneic hematopoietic stem-cell transplantation for myeloid sarcoma: a retrospective study from the SFGM-TC","volume":"26","author":"Chevallier","year":"2008","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clml.2017.02.027_bib47","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1038\/leu.2012.156","article-title":"Allogeneic hematopoietic stem cell transplantation for adult AML patients with granulocytic sarcoma","volume":"26","author":"Shimizu","year":"2012","journal-title":"Leukemia"},{"key":"10.1016\/j.clml.2017.02.027_bib48","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1177\/2040620711410774","article-title":"Myeloid sarcoma: current approach and therapeutic options","volume":"2","author":"Avni","year":"2011","journal-title":"Ther Adv Hematol"},{"key":"10.1016\/j.clml.2017.02.027_bib49","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1080\/1042819042000219485","article-title":"Gemtuzumab ozogamicin for relapsed and refractory acute myeloid leukemia and myeloid sarcomas","volume":"45","author":"Piccaluga","year":"2004","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.clml.2017.02.027_bib50","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1200\/JCO.2009.23.6976","article-title":"Acute myeloid leukemia with myeloid sarcoma and eosinophilia: prolonged remission and molecular response to imatinib","volume":"28","author":"Vedy","year":"2010","journal-title":"J\u00a0Clin Oncol"}],"container-title":["Clinical Lymphoma Myeloma and Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265016306309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265016306309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:29:11Z","timestamp":1761870551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2152265016306309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S2152265016306309"],"URL":"https:\/\/doi.org\/10.1016\/j.clml.2017.02.027","relation":{},"ISSN":["2152-2650"],"issn-type":[{"value":"2152-2650","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myeloid Sarcoma: Presentation, Diagnosis, and Treatment","name":"articletitle","label":"Article Title"},{"value":"Clinical Lymphoma Myeloma and Leukemia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clml.2017.02.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2017 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}